<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation K43R
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 36
Isolates 36
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Belec (2000)r31r31_m12AF204352IDV52G48V L10V, I15V, Q18E, E35D, M36I, R41K, K43R, R57K, I62V, L63AF
Masciotra (2000)SM40SM40AF221046PINA  L10I, I15V, E35D, M36I, R41K, K43R, R57K, Q61D, I64L, T96SF
de Sa Filho (2003)BREPM022BREPM022AY182789IDV D30N, I84V L10I, G16E, P39S, K43R, R57K, Q61N, I64V, V77I, G86R, L89M, I93LF
Gomez-Carrillo (2004)109902109902AY365826PINA  I15V, G16E, K20M, E35D, M36I, R41K, K43R, R57K, Q61N, I72TF
 120606120606AY365983PINA  L10V, I15V, E35D, M36I, R41K, K43R, R57K, Q61N, Q92R, I93LF
Non-B Workgroup (2005)PL882265161 SQV, IDV, LPV270G48M, I54V, V82AL24I, F53LL10I, T12I, I15V, G17E, K20M, E35D, M36IV, N37K, L38M, K43R, R57K, Q61N, L63PF
Baxter (2006)48-10071007-30609DQ877312PINAM46I, I47V, I54V, V82A, L90MF53LL10V, L19LI, K20R, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, I62V, L63LP, A71V, I85V, I93LF
 48-22512251-30925DQ877885PINAG48M, I54V, V82AL24I, F53L, G73GCFVL10I, T12I, I15V, G17E, K20M, E35D, M36I, K43R, R57K, Q61N, I62IV, L63P, T91TSF
 48-92179217-30908DQ877511PINAM46FL, I54V, V82A, L90ML33IL10I, I15V, K20R, E35D, M36I, N37E, R41K, K43R, R57K, Q61N, L63A, A71V, Q92K, I93LF
Sanabani (2006)02BR03402BR034DQ358812PINAL90M G16E, K20M, E35D, M36V, R41K, K43R, R57K, Q61N, L89MF
Aulicino (2011)3006-M668AS3006-M668ASHQ158167PINAM46L T12Q, K14R, I15V, M36I, R41K, K43R, Q61N, L63P, I72V, Q92TF
Jones (2012)137292137292JN669563PINA  I15V, E35D, M36I, N37D, R41K, K43R, R57K, D60E, Q61NF
 148547148547JN669716PINA  I15V, G16E, E35ED, M36I, P39PS, R41K, K43R, R57K, Q61N, L63T, E65D, I72ITF
 149933149933JN669741PINAL90M L10V, T12K, I15V, K20R, E35D, M36I, N37D, K43R, R57K, Q61DF
 152881152881JN669789PINA  L10I, T12K, I15V, E35ED, M36I, R41K, K43R, R57K, Q61N, L63T, I93LF
 154204154204JN669811PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61N, I93LF
 154303154303JN669816PINAD30N, L90MN88DI13V, I15V, K20T, E35N, M36I, R41K, K43R, K55N, R57K, Q61N, L63P, A71V, Q92KF
 157578157578JN669892PINAD30N, I54VN88DK14R, G17E, K20R, E35D, M36V, N37E, R41K, K43R, R57K, Q61N, L63T, E65D, H69Y, I72T, T74S, L89MF
 157841157841JN669901PINA  I15V, E35D, M36I, R41K, K43R, R57K, D60E, Q61D, L63V, I72TF
 158405158405JN669916PINA  T12E, I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, I62IV, H69RF
 163240163240JN670058PINAI54V, V82A, L90MQ58EL10V, I15V, G16A, K20R, E35D, M36I, N37D, R41K, K43R, R57K, Q61D, L63P, I72V, I93IVF
 164791164791JN670083PINA  I15V, G16E, K20R, E35D, M36I, P39S, R41K, K43R, R57K, Q61N, L63S, I72TF
 171375171375JN670258PINAI54V, V82AL24LIL10V, I15V, K20M, E35D, M36I, N37D, R41K, K43R, K45KR, R57K, Q61N, H69Y, A71AV, I72TF
 178684178684JN670487PINA  T12N, I15V, L19I, M36I, R41K, K43R, R57K, D60E, Q61D, L63AF
 179078179078JN670500PINAD30N, I54V, L90ML33I, N88DL10V, I15V, E35D, M36I, N37D, R41K, K43R, K45R, R57K, Q61N, I62V, L63P, I93LF
 185011185011JN670694PINAV82VA I15V, E35D, M36I, N37D, R41K, K43R, R57K, Q61D, I93LF
 190338190338JN670794PINA  I15V, G17E, K20M, E35D, M36I, R41K, K43R, R57K, Q61NF
 192524192524JN670856PINA  I15V, L19IMV, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63LVF
 194537194537JN670939PINA  I15V, G17E, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, K70KR, I72VF
 195206195206JN670972PINA  L10I, T12K, I15V, M36I, R41K, K43R, R57K, Q61N, L63T, I93LF
 196326196326JN671020PINA  T12E, I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63V, I72TF
 200571200571JN671203PINAI54IV I15V, E35D, M36I, N37D, R41K, K43R, R57K, Q61DF
 201993201993JN671248PINA  I15V, K20R, E35ED, M36I, R41K, K43R, R57K, Q61N, L63Q, E65ED, I72ITF
 202340202340JN671267PINA  T12N, I15V, L19I, E35D, M36I, R41K, K43R, R57K, Q61D, I64IVF
 203089203089JN671296PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61N, I72TF
 206166206166JN671394PINAM46L, I54V, V82AL24IL10I, I15V, A22V, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, A71VF