<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation K43R
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 54
Isolates 54
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
de Sa Filho (2003)BREPM022BREPM022AY182789IDV D30N, I84V L10I, G16E, P39S, K43R, R57K, Q61N, I64V, V77I, G86R, L89M, I93LF
Gomez-Carrillo (2004)109902109902AY365826PINA  I15V, G16E, K20M, E35D, M36I, R41K, K43R, R57K, Q61N, I72TF
Baxter (2006)48-11391139-30814DQ877399PINAM46L, G48V, I54T, V82AL24IL10I, K20R, E35D, M36I, N37DE, R41K, K43R, R57K, Q61N, L63C, T74S, L89MF
Sanabani (2006)02BR03402BR034DQ358812PINAL90M G16E, K20M, E35D, M36V, R41K, K43R, R57K, Q61N, L89MF
Waleria-Aleixo (2008)08RJ06060408RJ060604FJ591764PINAD30N, M46IN88DL10V, G16Q, E35D, M36V, P39T, R41K, K43R, R57K, D60E, Q61N, T74S, L89MF
 RG4RG4FJ592023PINA  T12A, E35D, M36I, R41K, K43R, R57K, Q61N, L63A, I72VF
Aulicino (2011)ARL411LCOARL411LCOFJ525808PINAD30NN88DL10Y, I13V, I15V, K20T, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63H, I72V, V75IF
 3006-M668AS3006-M668ASHQ158167PINAM46L T12Q, K14R, I15V, M36I, R41K, K43R, Q61N, L63P, I72V, Q92TF
Aulicino (2012)PE02PCR0155PCR0155EU581828PINA  E35D, M36I, R41K, K43R, R57K, Q61N, L63P, I72V, Q92MF
 AR02ARG2233ARG2233EU581826PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61N, L63TF
 PY02PSP0073PSP0073EU581824PINA  K14R, I15V, E35D, M36I, R41K, K43R, R57K, Q61DF
 BO02BOL119BOL119EU581827PINA  I15V, G16E, E35D, M36I, P39S, R41K, K43R, R57K, Q61N, L63CF
Jones (2012)137292137292JN669563PINA  I15V, E35D, M36I, N37D, R41K, K43R, R57K, D60E, Q61NF
 148547148547JN669716PINA  I15V, G16E, E35ED, M36I, P39PS, R41K, K43R, R57K, Q61N, L63T, E65D, I72ITF
 149933149933JN669741PINAL90M L10V, T12K, I15V, K20R, E35D, M36I, N37D, K43R, R57K, Q61DF
 157578157578JN669892PINAD30N, I54VN88DK14R, G17E, K20R, E35D, M36V, N37E, R41K, K43R, R57K, Q61N, L63T, E65D, H69Y, I72T, T74S, L89MF
 157841157841JN669901PINA  I15V, E35D, M36I, R41K, K43R, R57K, D60E, Q61D, L63V, I72TF
 158405158405JN669916PINA  T12E, I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, I62IV, H69RF
 163240163240JN670058PINAI54V, V82A, L90MQ58EL10V, I15V, G16A, K20R, E35D, M36I, N37D, R41K, K43R, R57K, Q61D, L63P, I72V, I93IVF
 164791164791JN670083PINA  I15V, G16E, K20R, E35D, M36I, P39S, R41K, K43R, R57K, Q61N, L63S, I72TF
 169379169379JN670198PINAI50L, V82AQ58QEI15V, K20R, E34K, M36I, R41K, K43R, Q61D, L63T, E65D, I72T, T74SF
 175787175787JN670374PINA  T12N, L19I, E35D, M36I, R41K, K43R, R57K, Q61N, L63LP, I72IATVF
 178684178684JN670487PINA  T12N, I15V, L19I, M36I, R41K, K43R, R57K, D60E, Q61D, L63AF
 183778183778JN670660PINAL90M L10I, I15V, K20V, E35D, M36I, R41K, K43R, R57K, Q61N, I62V, L63P, T74S, I85V, Q92KF
 190338190338JN670794PINA  I15V, G17E, K20M, E35D, M36I, R41K, K43R, R57K, Q61NF
 194537194537JN670939PINA  I15V, G17E, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, K70KR, I72VF
 198926198926JN671140PINA  L10I, T12I, I15V, G16E, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, I93LF
 199278199278JN671158PINA  T12K, I15V, L19I, E35D, M36I, R41K, K43R, R57K, Q61E, I62V, L63P, T74AF
 200571200571JN671203PINAI54IV I15V, E35D, M36I, N37D, R41K, K43R, R57K, Q61DF
 201750201750JN671235PINA  I13V, E35D, M36I, R41K, K43R, R57K, D60E, Q61D, I62V, L63C, T91VF
 203089203089JN671296PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61N, I72TF
 205762205762JN671371PINA  E35D, M36I, R41K, K43R, K55KE, R57K, Q61D, L63P, L89LPF
Diaz (2015)RenG17082RenG17082KT748110PINAM46I, I50L, V82A, L90ML10LF, L33F, F53L, L89VI13V, I15V, K20T, E35N, M36I, N37D, R41K, K43R, K55KR, R57K, Q61N, L63P, A71IV, Q92KF
 RenG16929RenG16929KT747957PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61NF
 RenG15778RenG15778KT746806PINA  L10V, G17E, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63A, E65DF
 RenG16838RenG16838KT747866PINA  L10P, V11G, I15V, G16E, E21K, M36I, R41K, K43R, R57K, Q61N, E65D, I72T, L89MF
 RenG16557RenG16557KT747585PINA  K14R, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, V82I, L89MF
 RenG15251RenG15251KT746279PINA  L10M, Q18H, E35D, M36I, R41K, K43R, R57K, Q61N, L63DV, C67DF
 RenG14425RenG14425KT745453PINAV32I, I47A, L90M L10I, I13V, L19I, E35D, M36I, N37E, K43R, R57K, Q61N, L63P, V82I, L89IF
 RenG15076RenG15076KT746104PINAM46I, V82FF53L, N83DW6V, L10V, I13A, A22V, E35D, M36I, R41K, K43R, R57K, Q61N, I62V, L63P, H69R, T74S, L89I, I93LF
 RenG14494RenG14494KT745522PINA  W6G, L10V, T12I, I13V, I15V, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63LP, I72T, L89MF
 RenG13651RenG13651KT744679PINA  E35D, M36I, R41K, K43R, R57K, Q61N, L63A, I64LF
 RenG15423RenG15423KT746451PINA  T12V, I15V, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63S, I64L, L89MF
 RenG12314RenG12314KT743342PINAD30N, I54LL33F, Q58QE, N88DR8P, L10V, I13V, I15V, K20T, T31A, E35D, M36I, K43R, R57K, Q61N, L63C, T74S, L89IMF
 RenG12957RenG12957KT743985PINA  T12TI, K14KR, I15V, G16GE, K20R, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63A, L89M, Q92KF
 RenG12367RenG12367KT743395PINA  T12Q, E35D, M36I, R41K, K43R, R57K, Q61N, L63H, E65ED, K70RF
 RenG12505RenG12505KT743533PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61N, L89M, I93ILF
 RenG12160RenG12160KT743188PINA  K14R, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, I72T, L89MF
 RenG11995RenG11995KT743023PINAV32I, M46I, I47V, I54A, V82A L10I, T12A, I15V, L19P, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, I64V, A71V, Q92KF
 RenG12768RenG12768KT743796PINA  K20I, E35D, M36I, R41K, K43R, R57K, Q61N, T74S, L89I, I93LF
 RenG11617RenG11617KT742645PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, K70R, L89MF
 RenG10501RenG10501KT741529PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61NF
 RenG11761RenG11761KT742789PINA  T12Q, M36I, R41K, K43R, R57K, Q61N, L63H, K70RF
 RenG11119RenG11119KT742147PINAI50LL33LF, F53LG17E, K20R, E35D, M36I, N37DE, R41K, K43R, K45N, R57K, D60N, Q61N, L63T, I72T, V82VI, L89MF