<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation K43R
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 57
Isolates 57
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Belec (2000)r31r31_m12AF204352IDV52G48V L10V, I15V, Q18E, E35D, M36I, R41K, K43R, R57K, I62V, L63AF
Masciotra (2000)SM40SM40AF221046PINA  L10I, I15V, E35D, M36I, R41K, K43R, R57K, Q61D, I64L, T96SF
de Sa Filho (2003)BREPM022BREPM022AY182789IDV D30N, I84V L10I, G16E, P39S, K43R, R57K, Q61N, I64V, V77I, G86R, L89M, I93LF
Gomez-Carrillo (2004)109902109902AY365826PINA  I15V, G16E, K20M, E35D, M36I, R41K, K43R, R57K, Q61N, I72TF
 120606120606AY365983PINA  L10V, I15V, E35D, M36I, R41K, K43R, R57K, Q61N, Q92R, I93LF
Non-B Workgroup (2005)PL882265161 SQV, IDV, LPV270G48M, I54V, V82AL24I, F53LL10I, T12I, I15V, G17E, K20M, E35D, M36IV, N37K, L38M, K43R, R57K, Q61N, L63PF
Baxter (2006)48-10071007-30609DQ877312PINAM46I, I47V, I54V, V82A, L90MF53LL10V, L19LI, K20R, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, I62V, L63LP, A71V, I85V, I93LF
 48-22512251-30925DQ877885PINAG48M, I54V, V82AL24I, F53L, G73GCFVL10I, T12I, I15V, G17E, K20M, E35D, M36I, K43R, R57K, Q61N, I62IV, L63P, T91TSF
 48-92179217-30908DQ877511PINAM46FL, I54V, V82A, L90ML33IL10I, I15V, K20R, E35D, M36I, N37E, R41K, K43R, R57K, Q61N, L63A, A71V, Q92K, I93LF
Sanabani (2006)02BR03402BR034DQ358812PINAL90M G16E, K20M, E35D, M36V, R41K, K43R, R57K, Q61N, L89MF
Aulicino (2011)3006-M668AS3006-M668ASHQ158167PINAM46L T12Q, K14R, I15V, M36I, R41K, K43R, Q61N, L63P, I72V, Q92TF
Jones (2012)137292137292JN669563PINA  I15V, E35D, M36I, N37D, R41K, K43R, R57K, D60E, Q61NF
 148547148547JN669716PINA  I15V, G16E, E35ED, M36I, P39PS, R41K, K43R, R57K, Q61N, L63T, E65D, I72ITF
 149933149933JN669741PINAL90M L10V, T12K, I15V, K20R, E35D, M36I, N37D, K43R, R57K, Q61DF
 152881152881JN669789PINA  L10I, T12K, I15V, E35ED, M36I, R41K, K43R, R57K, Q61N, L63T, I93LF
 154204154204JN669811PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61N, I93LF
 154303154303JN669816PINAD30N, L90MN88DI13V, I15V, K20T, E35N, M36I, R41K, K43R, K55N, R57K, Q61N, L63P, A71V, Q92KF
 157578157578JN669892PINAD30N, I54VN88DK14R, G17E, K20R, E35D, M36V, N37E, R41K, K43R, R57K, Q61N, L63T, E65D, H69Y, I72T, T74S, L89MF
 157841157841JN669901PINA  I15V, E35D, M36I, R41K, K43R, R57K, D60E, Q61D, L63V, I72TF
 158405158405JN669916PINA  T12E, I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, I62IV, H69RF
 163240163240JN670058PINAI54V, V82A, L90MQ58EL10V, I15V, G16A, K20R, E35D, M36I, N37D, R41K, K43R, R57K, Q61D, L63P, I72V, I93IVF
 164791164791JN670083PINA  I15V, G16E, K20R, E35D, M36I, P39S, R41K, K43R, R57K, Q61N, L63S, I72TF
 171375171375JN670258PINAI54V, V82AL24LIL10V, I15V, K20M, E35D, M36I, N37D, R41K, K43R, K45KR, R57K, Q61N, H69Y, A71AV, I72TF
 178684178684JN670487PINA  T12N, I15V, L19I, M36I, R41K, K43R, R57K, D60E, Q61D, L63AF
 179078179078JN670500PINAD30N, I54V, L90ML33I, N88DL10V, I15V, E35D, M36I, N37D, R41K, K43R, K45R, R57K, Q61N, I62V, L63P, I93LF
 185011185011JN670694PINAV82VA I15V, E35D, M36I, N37D, R41K, K43R, R57K, Q61D, I93LF
 190338190338JN670794PINA  I15V, G17E, K20M, E35D, M36I, R41K, K43R, R57K, Q61NF
 192524192524JN670856PINA  I15V, L19IMV, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63LVF
 194537194537JN670939PINA  I15V, G17E, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, K70KR, I72VF
 195206195206JN670972PINA  L10I, T12K, I15V, M36I, R41K, K43R, R57K, Q61N, L63T, I93LF
 196326196326JN671020PINA  T12E, I15V, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63V, I72TF
 200571200571JN671203PINAI54IV I15V, E35D, M36I, N37D, R41K, K43R, R57K, Q61DF
 201993201993JN671248PINA  I15V, K20R, E35ED, M36I, R41K, K43R, R57K, Q61N, L63Q, E65ED, I72ITF
 202340202340JN671267PINA  T12N, I15V, L19I, E35D, M36I, R41K, K43R, R57K, Q61D, I64IVF
 203089203089JN671296PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61N, I72TF
 206166206166JN671394PINAM46L, I54V, V82AL24IL10I, I15V, A22V, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, A71VF
Diaz (2015)RenG16929RenG16929KT747957PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61NF
 RenG15778RenG15778KT746806PINA  L10V, G17E, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63A, E65DF
 RenG16838RenG16838KT747866PINA  L10P, V11G, I15V, G16E, E21K, M36I, R41K, K43R, R57K, Q61N, E65D, I72T, L89MF
 RenG16557RenG16557KT747585PINA  K14R, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, V82I, L89MF
 RenG14710RenG14710KT745738PINA  L10I, I15V, L19Q, E35D, M36I, R41K, K43R, R57K, Q61N, L63V, E65ED, I72T, V82I, I93LF
 RenG14494RenG14494KT745522PINA  W6G, L10V, T12I, I13V, I15V, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63LP, I72T, L89MF
 RenG13651RenG13651KT744679PINA  E35D, M36I, R41K, K43R, R57K, Q61N, L63A, I64LF
 RenG14706RenG14706KT745734PINAM46MI I15V, E35D, M36I, R41K, K43R, R57K, Q61N, L63PF
 RenG15423RenG15423KT746451PINA  T12V, I15V, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63S, I64L, L89MF
 RenG12314RenG12314KT743342PINAD30N, I54LL33F, Q58QE, N88DR8P, L10V, I13V, I15V, K20T, T31A, E35D, M36I, K43R, R57K, Q61N, L63C, T74S, L89IMF
 RenG12957RenG12957KT743985PINA  T12TI, K14KR, I15V, G16GE, K20R, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63A, L89M, Q92KF
 RenG12367RenG12367KT743395PINA  T12Q, E35D, M36I, R41K, K43R, R57K, Q61N, L63H, E65ED, K70RF
 RenG12505RenG12505KT743533PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61N, L89M, I93ILF
 RenG12924RenG12924KT743952PINA  L10I, T12N, I15V, K20R, M36I, R41K, K43R, R57K, Q61D, L63T, E65D, I72T, I93LF
 RenG12160RenG12160KT743188PINA  K14R, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, I72T, L89MF
 RenG11995RenG11995KT743023PINAV32I, M46I, I47V, I54A, V82A L10I, T12A, I15V, L19P, K20R, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, I64V, A71V, Q92KF
 RenG12768RenG12768KT743796PINA  K20I, E35D, M36I, R41K, K43R, R57K, Q61N, T74S, L89I, I93LF
 RenG11617RenG11617KT742645PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, K70R, L89MF
 RenG10501RenG10501KT741529PINA  I15V, E35D, M36I, R41K, K43R, R57K, Q61NF
 RenG11761RenG11761KT742789PINA  T12Q, M36I, R41K, K43R, R57K, Q61N, L63H, K70RF
 RenG10211RenG10211KT741239PINA  T12K, I15V, L19T, E35D, M36I, R41K, K43R, R57RK, Q61N, L63CS, E65DF