<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation M36V
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 38
Isolates 38
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Dumans (2004)RG046RG046AY390209RTV, NFV189M46ML, I54V, L90M L10V, I15IV, K20R, E35D, M36V, N37E, R57K, D60E, Q61DN, I62V, L63LP, A71V, I72T, V77I, I93LF
Gomez-Carrillo (2004)101510101510AY365641PINAD30NN88DI15V, K20R, E35D, M36V, R57K, Q61D, I62V, L63P, I93LF
 103182103182AY365670PINAM46I, I54V, V82A I15V, K20R, E35D, M36V, R41K, K45R, R57K, Q61D, T74SF
 107858107858AY365777PINAM46I, I54V, V82AL24IL10I, I15V, K20M, E35D, M36V, P39T, R41K, K55R, R57K, Q61DN, L63PRST, A71V, I93LF
Rodrigues (2005)BLF_Pat16BR03SP111AY643159SQV, IDV, NFV293D30NN88DL10I, I13V, I15V, K20R, E35D, M36V, N37NS, R41K, R57K, Q61N, I62IV, L63LP, E65D, A71I, I72TF
Baxter (2006)48-10891089-30716DQ877344PINAM46L, I54V, L90M T12N, I15V, G16GE, K20RT, E35D, M36V, P39S, R41K, R57K, Q61N, I62V, L63V, A71I, I72T, V77VI, I93LF
 48-10551055-30707DQ877421PINAM46I, I47V, I54V, V82F, L90MF53FLL10I, K20I, E35D, M36V, R41K, R57K, Q61N, I62IV, L63Q, I64IV, A71V, T74S, I93LF
 48-30433043-30305DQ877955PINAM46I, G48M, I54V, L76V, V82A, L90MK43T, F53LT4S, L10V, K14Q, I15V, G16E, L19I, K20R, E35D, M36V, P39S, K55R, R57K, Q61N, I62V, L63T, E65H, H69R, I72V, T74S, L89M, C95CSF
Sanabani (2006)02BR03402BR034DQ358812PINAL90M G16E, K20M, E35D, M36V, R41K, K43R, R57K, Q61N, L89MF
Cardoso (2009)3131BRGO3131FJ638460PINAM46L, I54V, L76V, V82M, L90M L10V, I15V, K20R, E35D, M36V, N37E, R41K, K55R, R57K, Q61N, L63P, A71V, T74TS, I93LF
Dumans (2009)RENA654RENA654FJ405122RTV, NFV, LPV356M46L, I54V, V82A, L90M L10V, I15V, K20R, E35D, M36V, N37E, R57K, D60E, Q61D, I62V, A71V, I72T, V77I, I93LF
Aulicino (2011)ARM640RCAARM640RCAFJ525835PINAD30NN88DL10V, T12I, I15V, G16E, E35D, M36V, N37E, R41K, K45R, R57K, Q61N, L63T, I72T, V77I, I93LF
Jones (2012)145844145844JN669665PINAI54V, V82A, L90MF53L, Q58EL10I, I15V, G16E, K20R, E35D, M36V, R41K, K55R, R57K, Q61N, L63T, A71V, I72IATV, I93LF
 157578157578JN669892PINAD30N, I54VN88DK14R, G17E, K20R, E35D, M36V, N37E, R41K, K43R, R57K, Q61N, L63T, E65D, H69Y, I72T, T74S, L89MF
 159110159110JN669944PINAI54V, V82ML24I, K43TL10I, I15V, L19Q, K20R, E35D, M36V, R41K, R57K, Q61N, I62V, L63P, T74S, L89M, Q92KF
 176630176630JN670406PINAL90M I15V, K20M, E35D, M36V, R41K, R57K, Q61N, I62IV, L63A, I93LF
 196419196419JN671023PINAD30NN88DL10I, I13V, I15V, K20KR, E35D, M36V, R41K, R57K, Q61DN, L63AV, I93LF
Diaz (2015)RenG17425RenG17425KT748453PINAD30N, I54VN88DL10Y, T12TA, I15V, G16E, K20R, E35D, M36V, P39Q, R41RK, R57K, D60E, Q61D, L63T, A71V, I72T, L89T, I93LF
 RenG16849RenG16849KT747877PINAM46IF53L, N88TL10V, I15IV, G16E, L19I, K20T, E35D, M36V, N37T, P39T, R41I, K45Q, R57K, D60DE, Q61N, I62V, L63A, E65D, V77I, L89MF
 RenG14903RenG14903KT745931PINAM46I, I47V, I54V, V82AF53LL10I, I15V, G16E, K20M, E35D, M36V, R57K, Q61N, E65D, A71V, I72T, I93LF
 RenG15083RenG15083KT746111PINAM46L, N88S L10V, I15V, G16E, K20R, E35D, M36V, R41K, R57K, Q61N, L63T, E65D, I72TF
 RenG14415RenG14415KT745443PINAM46ML, I54L, L90ML23LI, F53LL10IV, I15V, G16E, K20T, E35D, M36V, P39PS, R41K, R57K, Q61N, L63T, A71AV, I72T, T74S, I85V, L89IM, I93LF
 RenG13858RenG13858KT744886PINAM46L, G48GS, I54V, V82A, L90ML33LF, K43T, T74PL10V, G16E, L19I, K20R, E35D, M36V, P39T, R41K, R57K, Q61D, I62V, A71V, I72R, I93LF
 RenG13942RenG13942KT744970PINAN88S L10V, G16E, K20R, E35D, M36V, P39S, K45R, R57K, Q61D, L63V, E65D, I72V, L89MF
 RenG15176RenG15176KT746204PINAD30N, M46L, I50L, V82AL33FL10V, T12TM, I15V, G16E, K20R, E35D, M36V, P39S, R41K, K43Q, R57K, Q61N, L63T, I64V, E65D, A71V, I72T, V77I, I93LF
 RenG14280RenG14280KT745308PINAI54V, L90ML23I, F53LL10I, K20I, E35N, M36V, R41K, K55KR, R57K, D60E, Q61N, I62IV, L63D, I64IV, E65ED, I66IF, K70R, A71V, I72T, L89M, Q92QK, I93ILF
 RenG14546RenG14546KT745574PINAL90M L10V, I15V, G16E, K20R, E35D, M36V, R41K, R57K, Q61N, I62V, L63T, I72T, V77I, L89M, I93LF
 RenG14069RenG14069KT745097PINAD30N, M46L, V82AL24I, L33F, K43TL10I, I15IV, G16E, K20R, E35D, M36V, N37T, P39S, R41K, R57K, Q61N, I62V, L63P, A71V, V75I, V77I, I93LF
 RenG13251RenG13251KT744279PINAM46I, L76V, V82A I15V, K20T, E34K, E35D, M36V, P39S, R41K, R57K, D60E, Q61N, I62V, L63P, T74S, L89MF
 RenG12449RenG12449KT743477PINAM46I, I54A, V82L, L90MQ58EL10I, K14R, I15V, G16Q, K20T, E35N, M36V, N37S, P39S, R41K, F53FY, R57K, D60E, Q61N, L63T, C67E, H69Y, A71V, I72T, V77I, I93LF
 RenG12174RenG12174KT743202PINAD30N, M46L, I54V, V82AL24I, L33FL10IV, I15V, G16E, K20R, E35D, M36V, P39S, R41K, K43Q, R57K, Q61N, L63T, I64V, E65D, A71V, I72T, V77I, Q92K, I93LF
 RenG12893RenG12893KT743921PINAM46I, I50V, I54V, V82A, L90MQ58EL10V, I15V, G16E, K20R, E35D, M36V, P39S, R41K, K55R, R57K, D60E, Q61N, L63T, E65D, A71V, I72T, V77VI, L89M, I93LF
 RenG13021RenG13021KT744049PINAN88SF53L, Q58EL10I, G16E, K20T, E35D, M36V, N37H, P39S, R41K, R57K, D60E, Q61D, L63C, A71V, V77IL, L89M, I93LF
 RenG11513RenG11513KT742541PINA  K14R, I15V, E35D, M36V, R41K, R57RK, Q61D, I64IL, L89MF
 RenG10656RenG10656KT741684PINAD30N, M46LL23I, F53L, Q58E, N88DL10I, T12I, I13V, I15V, G16E, K20T, E35D, M36V, P39S, R41K, R57K, Q61N, I62V, A71T, I72R, V77I, L89TF
 RenG10389RenG10389KT741417PINA  G16E, E35D, M36V, R41K, R57K, Q61N, L63S, E65D, I72T, L89MF
 RenG11532RenG11532KT742560PINAG48A, I54A, V82A W6W*, L10V, T12I, I13V, I15V, G16E, K20R, E35D, M36V, N37K, R41K, R57K, Q61N, L63T, I72T, T74S, L89MF
 RenG11703RenG11703KT742731PINAM46L, I54V, V82F, L90MF53LL10V, K20R, E35D, M36V, N37NT, R41K, K55R, R57K, D60E, Q61N, I62V, L63P, I64IV, A71AITV, I72IV, V77I, I85IV, L89IM, I93LF