<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation M36L
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 19
Isolates 19
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Machado (2004)CS172proCS172proAY502095Unknown, NFV>21M46LN83DG16E, M36L, N37K, R41K, R57K, Q61D, I72R, L89IF
de Sa Filho (2005)BREPM275BREPM275AY771592PINAD30NL33F, N88DL10V, T12K, I13V, I15V, K20T, E35D, M36L, N37E, K55R, R57K, D60E, Q61N, L63S, L89MF
Rodrigues (2005)BLF_Pat19BR02SP234AY643143SQV, IDV223  I15V, E35D, M36L, R41K, R57K, Q61N, L63S, E65D, I72VF
Baxter (2006)48-32663266-30729DQ878171PINAM46I, I54V, V82AV11VI, L24I, L33F, L89VL10I, I15V, K20A, E35DN, M36L, N37Q, R41K, K55R, R57RK, D60E, Q61E, I62V, L63P, I64L, A71V, I72M, V77I, T91S, I93LF
Sanabani (2010)81007BR_FPS810HM026459PINAD30N, I50L, V82AL33F, N88DL10V, I13V, I15V, K20R, E35D, M36L, R41K, K45Q, R57K, Q61N, L63P, I64L, A71V, I93LF
Jones (2012)181732181732JN670583PINAM46L, I54V, V82AL24I, L33F, G73CL10I, E35D, M36L, N37ND, R41K, K55R, R57K, Q61N, L63P, Q92KF
Diaz (2015)RenG17077RenG17077KT748105PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41PQ, R57K, Q61N, I62V, L63P, A71I, V77I, L89TF
 RenG16459RenG16459KT747487PINAM46I, I54V, V82F, L90ML33I, K43TL10V, I13V, K20T, E35D, M36L, N37D, R41K, F53Y, R57K, Q61N, I62V, L63P, T74S, V77I, L89I, I93LF
 RenG16792RenG16792KT747820PINA  E35D, M36L, N37E, R41K, R57K, D60E, Q61N, L63P, C67E, K70RF
 RenG15740RenG15740KT746768PINAM46I, V82AV32A, L33F, F53LL10I, I13V, G16E, K20R, E35D, M36L, R41K, Q61N, L63T, I66F, I72T, T74A, L89MF
 RenG15411RenG15411KT746439PINA F53FLL10V, I15V, E35D, M36L, L38W, R41K, K45KR, R57K, Q61D, I62V, L63LP, I64M, T74A, L89MF
 RenG14349RenG14349KT745377PINAM46I, I54V, V82AL24I, L33FL10V, T12A, I13V, G16E, Q18E, L19LP, K20T, E35D, M36L, R41K, R57K, Q61N, I64V, H69Q, A71V, I72R, I93LF
 RenG13655RenG13655KT744683PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41P, K55KR, R57K, Q61N, I62V, L63P, A71I, I72IV, V77I, L89TF
 RenG14774RenG14774KT745802PINA  T12A, I15V, L19I, E35D, M36L, R41K, R57K, Q61N, L63SF
 RenG12665RenG12665KT743693PINAG48QR, I84V, L90ML33F, N83DL10V, K20R, E35D, M36L, R41K, R57K, Q61D, I62V, L63P, T74S, L89IF
 RenG13505RenG13505KT744533PINAL90M L10V, I13V, K20R, E35D, M36L, R41K, R57K, Q61N, I62V, L63P, T74S, L89I, I93LF
 RenG11793RenG11793KT742821PINAG48A, I54V, V82AL24I, L33F, K43T, T74P, N83DL10I, I13V, K20R, E35D, M36L, R57K, Q61D, I62V, I72R, L89MF
 RenG10018RenG10018KT741046PINAD30N, I54V, V82A, L90ML33F, N88DT12I, I13V, K14R, I15V, K20R, E35D, M36L, N37D, R41K, K45I, R57K, Q61N, I62V, L63P, G68E, H69R, I72IV, L89IF
 RenG11057RenG11057KT742085PINA  I13V, I15V, E35D_IN, M36L, P39Q, R41K, R57K, Q61N, K70R, L89MF