<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation M36L
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 31
Isolates 31
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)106671106671AY365754PINAM46I, I50V, V82A, L90ML33F, K43TL10I, I13V, I15V, G16E, K20R, E35D, M36L, R41K, R57K, Q61N, L63S, E65D, A71V, T74S, I93LF
 119804119804AY365974PINAM46L, G48V, I54V, L76V, V82A, L90ML33F, K43TL10I, I15V, G16E, K20M, E35H, M36L, R41K, K55R, R57K, Q61N, L63S, E65D, A71V, T74S, I93LF
Machado (2004)CS172proCS172proAY502095Unknown, NFV>21M46LN83DG16E, M36L, N37K, R41K, R57K, Q61D, I72R, L89IF
de Sa Filho (2005)BREPM275BREPM275AY771592PINAD30NL33F, N88DL10V, T12K, I13V, I15V, K20T, E35D, M36L, N37E, K55R, R57K, D60E, Q61N, L63S, L89MF
Rodrigues (2005)BLF_Pat19BR02SP234AY643143SQV, IDV223  I15V, E35D, M36L, R41K, R57K, Q61N, L63S, E65D, I72VF
Baxter (2006)48-11031103-30708DQ877410PINAM46L, I54V, L76V, V82A, L90ML33F, K43TL10I, I13V, I15V, G16E, K20M, E35H, M36L, R41K_K, K55R, R57K, Q61N, L63S, E65D, A71V, T74S, L89LM, I93LF
 48-32663266-30729DQ878171PINAM46I, I54V, V82AV11VI, L24I, L33F, L89VL10I, I15V, K20A, E35DN, M36L, N37Q, R41K, K55R, R57RK, D60E, Q61E, I62V, L63P, I64L, A71V, I72M, V77I, T91S, I93LF
 48-91269126-30918DQ877726PINA  T12S, I15V, L19I, M36L, R57K, D60DE, Q61QHKN, I62IV, L63PS, I64IV, A71AT, I93LF
Sanabani (2010)81007BR_FPS810HM026459PINAD30N, I50L, V82AL33F, N88DL10V, I13V, I15V, K20R, E35D, M36L, R41K, K45Q, R57K, Q61N, L63P, I64L, A71V, I93LF
Aulicino (2011)ARL550FANARL550FANFJ525810PINAI54V, V82A, L90MI50T, Q58EL10I, I15V, Q18E, E35D, M36L, L38W, R41K, R57K, Q61N, I62V, L63P, A71V, I93LF
 ARN272RLDARN272RLDFJ525856PINAM46L, I54V, V82TL33F, N83DL10I, T12E, E35D, M36L, R41K, K55R, R57K, Q61N, L63P, I64M, K70T, A71V, I72T, Q92KF
Jones (2012)128987128987JN669458PINA  L10V, I15V, E35D, M36L, N37D, R41K, R57K, D60E, Q61N, I93LF
 181732181732JN670583PINAM46L, I54V, V82AL24I, L33F, G73CL10I, E35D, M36L, N37ND, R41K, K55R, R57K, Q61N, L63P, Q92KF
 182465182465JN670612PINA  T12N, I15V, M36L, R41K, R57K, D60E, Q61D, L63LPF
 183504183504JN670649PINAM46I, I54V, V82A, L90ML33F, K43KT, F53L, T74PL10V, I15V, K20M, E35N, M36L, N37ND, L38W, R41K, K55R, R57K, Q61N, I62V, L63P, H69R, A71V, I72V, I93LF
 193364193364JN670895PINAM46L, I54V, V82AL24LI, L33F, G73CL10I, I13V, I15V, K20R, E35D, M36L, N37E, R41K, K55R, R57K, Q61N, I62V, L63P, I72T, T74S, V77VI, I93LF
 202645202645JN671283PINAM46ML, L76LV, V82VAF53FLL10V, I15V, M36L, L38LW, R41K, K55KR, R57K, D60DE, Q61N, I62IV, L63LP, A71AV, I93LF
Diaz (2015)RenG17077RenG17077KT748105PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41PQ, R57K, Q61N, I62V, L63P, A71I, V77I, L89TF
 RenG17490RenG17490KT748518PINAD30N, M46L, I54V, V82AL24I, L33F, N88DL10V, I13V, I15V, L19I, K20R, E35D, M36L, N37E, K45R, K55N, R57K, Q61G, V77VI, L89F, Q92RF
 RenG16459RenG16459KT747487PINAM46I, I54V, V82F, L90ML33I, K43TL10V, I13V, K20T, E35D, M36L, N37D, R41K, F53Y, R57K, Q61N, I62V, L63P, T74S, V77I, L89I, I93LF
 RenG15740RenG15740KT746768PINAM46I, V82AV32A, L33F, F53LL10I, I13V, G16E, K20R, E35D, M36L, R41K, Q61N, L63T, I66F, I72T, T74A, L89MF
 RenG15411RenG15411KT746439PINA F53FLL10V, I15V, E35D, M36L, L38W, R41K, K45KR, R57K, Q61D, I62V, L63LP, I64M, T74A, L89MF
 RenG14349RenG14349KT745377PINAM46I, I54V, V82AL24I, L33FL10V, T12A, I13V, G16E, Q18E, L19LP, K20T, E35D, M36L, R41K, R57K, Q61N, I64V, H69Q, A71V, I72R, I93LF
 RenG13655RenG13655KT744683PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41P, K55KR, R57K, Q61N, I62V, L63P, A71I, I72IV, V77I, L89TF
 RenG13680RenG13680KT744708PINAD30N, G48V, I54V, V82A, L90ML33F, N88DQ7D, L10V, I13IV, I15V, K20KR, L24LF, E35D, M36L, N37E, R57K, D60E, Q61D, I62V, L63P, C67S, A71V, I72IT, T74S, I93LF
 RenG14774RenG14774KT745802PINA  T12A, I15V, L19I, E35D, M36L, R41K, R57K, Q61N, L63SF
 RenG12665RenG12665KT743693PINAG48QR, I84V, L90ML33F, N83DL10V, K20R, E35D, M36L, R41K, R57K, Q61D, I62V, L63P, T74S, L89IF
 RenG13505RenG13505KT744533PINAL90M L10V, I13V, K20R, E35D, M36L, R41K, R57K, Q61N, I62V, L63P, T74S, L89I, I93LF
 RenG11793RenG11793KT742821PINAG48A, I54V, V82AL24I, L33F, K43T, T74P, N83DL10I, I13V, K20R, E35D, M36L, R57K, Q61D, I62V, I72R, L89MF
 RenG10018RenG10018KT741046PINAD30N, I54V, V82A, L90ML33F, N88DT12I, I13V, K14R, I15V, K20R, E35D, M36L, N37D, R41K, K45I, R57K, Q61N, I62V, L63P, G68E, H69R, I72IV, L89IF
 RenG11057RenG11057KT742085PINA  I13V, I15V, E35D_IN, M36L, P39Q, R41K, R57K, Q61N, K70R, L89MF