<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L33F
Rx >= 1 PI
IncludeMixtures No
References 15
Patients 170
Isolates 170
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)9629696296AY365523PINAI54V, V82AG, I84V, L90ML33F, Q58EQ7QH, L10I, T12TP, I13IV, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, A71V, I72RF
 9889798897AY365588PINAI54V, V82A, L90ML33F, K43KTL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, I62V, L63I, A71V, I72Q, I93LF
 103183103183AY365671PINAD30N, M46L, I54V, V82A, L90ML33F, N88DI13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63H, A71V, T74S, I93LF
de Sa Filho (2005)BREPM275BREPM275AY771592PINAD30NL33F, N88DL10V, T12K, I13V, I15V, K20T, E35D, M36L, N37E, K55R, R57K, D60E, Q61N, L63S, L89MF
Non-B Workgroup (2005)PL23900101500 Unknown, LPV>58I54V, V82AL33F, N83DL10V, I13V, K20R, E35D, M36I, R41K, R57K, I62V, T74S, L89IF
 PL36995591 Unknown, LPV>112M46L, G48V, I54V, V82A, L90ML33F, K43TL10V, I15V, G16E, K20M, E35N, M36I, N37ND, R57K, Q61D, G68E, H69R, A71T, I72R, L89I, I93LF
 PL4840688662 APV104M46MI, I50IV, V82AL33FL10I, T12I, I13V, I15IV, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, G68E, I72R, L89MF
Baxter (2006)48-12061206-30604DQ877750PINAM46L, I50V, I54V, V82AL24I, L33F, Q58EL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, H69Y, L89MF
 48-12711271-30923DQ877792PINAG48V, I54V, V82SL24I, L33F, Q58EL10I, I15V, G16E, K20R, E34Q, E35D, M36I, P39PT, R41K, R57K, I62V, L63T, E65D, I72T, L89MF
 48-26142614-30624DQ877904PINAM46L, I54V, V82AL33F, F53LL10V, T12I, I15V, G16E, L19V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, I85V, L89MF
 48-32663266-30729DQ878171PINAM46I, I54V, V82AV11VI, L24I, L33F, L89VL10I, I15V, K20A, E35DN, M36L, N37Q, R41K, K55R, R57RK, D60E, Q61E, I62V, L63P, I64L, A71V, I72M, V77I, T91S, I93LF
 48-42864286-30910DQ878509PINAI54AV, V82F, L90ML33F, K43T, F53LL10IV, G16E, L19I, K20R, E35D, M36I, N37T, P39T, R41K, D60E, Q61E, I62V, L63P, I64V, H69Q, A71V, I93LF
 48-61786178-30731DQ878750PINAM46MI, G48GV, I50V, I54V, V82TL33FL10V, I15V, K20R, E35D, M36I, P39PQ, R41K, R57K, Q61N, L63P, T74S, L89M, I93ILF
 48-90719071-30901DQ877285PINAM46I, I47V, I54V, V82A, L90ML33F, F53L, Q58E, N83DL10V, G16A, K20R, E35D, M36I, N37D, R57K, D60E, Q61N, L63P, L89IF
 48-93499349-30923DQ877289PINAV32I, M46I, I47V, G48M, I54M, V82AL33F, F53LL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I72T, T74S, L89IF
 48-91869186-30901DQ877291PINAM46L, I54V, V82AL24I, L33F, K43T, F53L, T74PL10I, I13V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I64L, A71V, I72T, L89I, I93LF
 48-90259025-30825DQ877501PINAM46I, I54S, V82AL33FL10I, I13V, I15V, K20M, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, T74S, L89IF
 48-92509250-30908DQ877602PINAM46L, I54V, V82AV11VI, L24I, L33F, T74PL10I, I13V, G17E, L19I, K20R, E35D, M36I, R41K, R57K, Q61DN, I62V, L63T, E65D, I72T, L89MF
 48-91499149-30826DQ877714PINAM46L, I54V, V82AL24I, L33F, K43T, F53LR8P, L10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, K70R, L89LM, Q92KF
Santos (2006)118118PRAY275778SQV, IDV, RTV, APV, LPV287G48V, I50V, I54S, V82AL33F, Q58EL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37D, Q61N, L63T, I85V, L89MF
Waleria-Aleixo (2008)08RJ06060808RJ060608FJ591768PINA L33F, Q58EI13IV, G17E, E35D, N37K, P39S, R41K, R57K, D60E, Q61D, L63P, V77I, L89MF
 08RJ04011108RJ040111FJ591595PINAI54LV, I84V, L90ML33F, G73SL10I, K14R, G16E, K20R, E35D, M36I, P39S, R41K, K45R, R57K, Q61N, I62V, L63P, C67F, A71V, I72T, I85V, Q92KF
 08RJ06061808RJ060618FJ591778PINAM46I, I50V, L76V, V82AL24I, L33F, Q58EL10I, I13V, I15V, G16E, K20R, E35D, M36I, K55KR, R57K, Q61N, L63T, C67E, L89MF
 08RJ06057908RJ060579FJ591739PINAM46I, I50V, I54V, V82AL24I, L33F, K43T, T74PL10I, I13V, G16Q, K20R, E35D, M36I, P39A, R41K, K55R, R57K, D60E, Q61N, I62V, K70R, I72V, L89MF
 08PR05031308PR050313FJ591341PINAM46L, L90ML33F, G73GAL10V, I13IV, I15V, K20T, E35D, M36I, R41K, K55KR, R57K, Q61N, L63P, E65ED, C67CY, A71T, I72T, I85VF
Dumans (2009)RENA578RENA578FJ405042IDV, SQV, RTV, NFV, LPV335M46I, I54A, V82AL24I, L33F, Q58EL10I, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63A, L89MF
 RENA555RENA555FJ405127SQV, NFV, RTV, IDV, Unknown>191I54V, V82A, L90ML33F, K43T, F53L, T74PL10V, I13V, K14R, G16E, K20R, E35D, M36I, P39T, R41K, R57K, D60E, Q61N, I62V, L63H, A71I, I72V, I93LF
 RES28_02RES28_02FJ405158IDV, NFV, RTV, APV139M46L, I54V, V82AL33FL10I, G17D, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, E65D, L89MF
Charpentier (2010)T076006T076006HQ717826PI, DRV, RTVNAG48M, I54T, V82A, L90ML33F, Q58EL10I, T12M, I13V, G16E, K20R, E35D, M36I, R41K, L63T, E65D, I72T, T74A, L89MF
 T128002T128002HQ717825PI, DRV, RTVNAI54V, N88S, L90ML33FL10V, I13IV, K14R, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N, L63V, A71I, I72V, V77I, L89I, Q92K, I93LF
Sanabani (2010)81007BR_FPS810HM026459PINAD30N, I50L, V82AL33F, N88DL10V, I13V, I15V, K20R, E35D, M36L, R41K, K45Q, R57K, Q61N, L63P, I64L, A71V, I93LF
Aulicino (2011)ARK916CJARK916CJFJ525802PINAV82F, L90ML33FT12E, I13V, K14IV, I15V, K20Q, E35N, M36I, R41K, R57K, Q61N, I62IV, I64V, H69RF
 ARM522BCEARM522BCEFJ525832PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, K20R, E35N, M36I, K55R, R57K, Q61N, I62V, L63P, L89IF
 ARN156RJEARN156RJEFJ525852PINAD30N, M46I, I54V, V82AL24I, L33F, N83D, N88DL10I, K20R, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63D, A71V, I72PT, T74SF
Charpentier (2011)CR-51CR-51FJ688257PINAM46I, I54V, L76V, V82AL24I, L33F, Q58EL10I, I13V, K14R, I15IV, G16E, K20R, E35D, M36I, P39Q, R41K, K55R, I62V, L63ST, H69K, L89MF
Jones (2012)142103142103JN669613PINAM46L, V82A, L90ML33F, F53LL10V, I15V, G16E, K20R, E35D, M36I, P39S, R41EKQ, R57K, Q61D, L63T, E65D, A71V, I72T, I93LF
 146046146046JN669668PINAM46L, I54L, V82A, L90ML33FL10I, T12EQ, I15V, G16E, K20R, E34V, E35D, M36I, P39S, R41K, K55R, R57K, Q61N, I62V, L63T, A71V, I72T, T74S, L89M, I93LF
 157709157709JN669896PINAM46I, I54V, L76V, V82AL33F, K43KTL10I, I15IV, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63T, H69Y, I72T, L89M, I93LF
 164777164777JN670081PINAI54V, V82A, L90ML33F, G73SL10I, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, A71T, I72RF
 167774167774JN670161PINAV32I, I47V, I54M, N88S, L90LML33F, G73S, L89VT12I, I13V, I15V, G16E, K20R, E35ED, M36I, R41K, R57K, Q61N, G68GE, A71IV, I72T, V77VEF
 178038178038JN670468PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, K20R, E35N, M36I, N37NI, K55R, R57K, Q61N, I62V, L63P, L89IF
 181732181732JN670583PINAM46L, I54V, V82AL24I, L33F, G73CL10I, E35D, M36L, N37ND, R41K, K55R, R57K, Q61N, L63P, Q92KF
 184144184144JN670673PINAM46I, I50IL, I54AV, V82AL24I, L33F, Q58EL10I, T12N, I13V, G16GE, K20I, E35N, M36I, N37E, R41K, R57K, D60E, Q61N, L63T, I72T, L89MF
 188212188212JN670748PINAI54LL33FI15V, G16E, K20Q, E34A, E35D, M36I, P39S, R41K, R57K, D60E, Q61N, I62V, I72TF
 191048191048JN670808PINAM46I, I50V, I54V, V82AL33FL10V, K14KR, I15V, G16GE, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, I72V, T74S, L89MF
 195817195817JN671002PINAI54V, V82AL24I, L33F, K43T, N83DL10I, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63C, L89IF
 203943203943JN671324PINAV32I, M46I, I54V, V82AL24I, L33F, K43T, F53LL10I, I13V, G16E, K20R, E35D, M36I, N37D, P39PS, R57K, Q61N, L63S, E65D, K70Q, A71V, T74S, V77I, L89TF
 204754204754JN671350PINAM46I, I50V, I54V, V82AL33F, Q58EL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, L89MF
 207305207305JN671429PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, K20T, E35D, M36I, R41K, D60E, Q61N, I62V, L63T, I64L, C67D, A71V, I72T, I93LF
Kouri (2012)CU263-10CU263-10JQ585374PINAV32I, I54M, I84VV11I, L33F, F53FLQ2L, L5LF, L10V, I13V, K14E, I15V, G17D, K20R, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, L63P, I64V, A71V, T74E, V82IF
 CU772-10CU772-10JQ585416PINAM46L, I54AV, V82AL33F, T74AP, N83NDL10I, I13V, I15IV, G16E, K20R, E35D, M36I, N37D, R41K, R57K, L63T, E65D, L89MF
Grossman (2014)2727 LPV, SQV257G48M, I54V, V82AL24I, L33F, F53LL10I, I15V, Q18E, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, I72V, V75IF
Diaz (2015)RenG15609RenG15609KT746637PINAI50L, N88SL33FT12N, I13IV, I15V, L19I, K20I, E35N, M36I, N37D, R41K, R57K, Q61N, L63V, I64V, I72V, T74TA, V77VI, L89MF
 RenG17206RenG17206KT748234PINAM46I, I47V, I54V, V82A, L90ML33F, F53L, Q58EL10I, I13V, Q18IL, L19V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I66F, A71T, I72IM, L89I, Q92KF
 RenG16848RenG16848KT747876PINAM46I, I54V, L76V, V82AL33F, K43T, N83DL10V, I13V, L19V, K20R, E35D, M36I, N37NT, R41K, R57K, Q61N, I62V, I72R, T74S, L89MF
 RenG17082RenG17082KT748110PINAM46I, I50L, V82A, L90ML10LF, L33F, F53L, L89VI13V, I15V, K20T, E35N, M36I, N37D, R41K, K43R, K55KR, R57K, Q61N, L63P, A71IV, Q92KF
 RenG15726RenG15726KT746754PINAM46L, I54V, V82A, I84V, L90ML33F, K43KPQT, F53FL, T74PSL10V, I13V, I15V, K20R, E35D, M36I, N37D, P39PT, R41RK, K55KR, R57K, Q61N, I62V, L63P, I64L, H69HR, A71IT, L89MT, Q92KF
 RenG16059RenG16059KT747087PINAM46I, I54V, V82A, N88SL33F, K43KTL10I, I13V, I15V, K20T, E35D, M36I, R41N, R57K, Q61N, I62V, I64V, I72R, T74S, L89I, I93LF
 RenG17077RenG17077KT748105PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41PQ, R57K, Q61N, I62V, L63P, A71I, V77I, L89TF
 RenG17165RenG17165KT748193PINAV32I, M46L, I47IV, I54LV, V82A, I84VL24I, L33FL10I, I13V, G17D, L19I, K20R, E35D, M36I, K43I, R57K, Q61N, L63V, E65D, I72T, T74S, V77IL, L89MF
 RenG15889RenG15889KT746917PINAM46I, I54V, L76V, V82AL10F, L24I, L33FI13V, K20R, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, I72V, L89IF
 RenG17291RenG17291KT748319PINAM46I, I50L, V82A, N88SL33F, K43TL10V, I13V, K20R, E35D, M36I, R41KN, D60E, Q61D, L63P, V77VI, L89MF
 RenG16492RenG16492KT747520PINAM46L, I54V, V82AL24I, L33F, K43T, T74PL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, H69R, Q92KF
 RenG17232RenG17232KT748260PINAM46I, I47V, I50V, L76V, V82AV11I, L33F, F53LL10V, I13V, I15V, Q18L, L19Q, K20R, E34KNRS, E35D, M36I, N37D, R41K, R57K, Q61N, I66F, A71V, L89I, T91AF
 RenG16754RenG16754KT747782PINAV32I, M46I, I47V, I54M, V82VA, I84V, L90MV11I, L33F, K43TL10IV, I13V, E34K, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, I85IV, L89M, Q92QRF
 RenG17309RenG17309KT748337PINAM46I, I50V, V82A, L90ML33F, K43T, F53LL10V, G16E, K20R, E34N, E35D, M36I, P39S, R41K, K55R, R57K, D60E, Q61D, L63HP, A71I, V77I, L89M, I93LF
 RenG17021RenG17021KT748049PINAV32I, I47V, I50V, I54L, V82ML33F, K43T, T74PL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37S, R57K, Q61N, L63T, E65D, I72V, L89FF
 RenG15968RenG15968KT746996PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG15742RenG15742KT746770PINAG48V, I50V, I54V, V82A, L90ML33FL10IV, L19I, K20R, E34Q, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I72V, T74S, L89M, I93LF
 RenG15542RenG15542KT746570PINAI50L, N88SL33FI13V, K20R, E35D, M36I, N37D, R41K, K45R, R57K, D60E, Q61D, K70R, A71V, L89M, Q92KF
 RenG16517RenG16517KT747545PINAM46IV32A, L33FL10V, E35D, M36I, R41K, K45R, R57K, Q61N, L63T, E65D, I72T, T74A, L89MF
 RenG16229RenG16229KT747257PINAM46I, I54IV, L76LV, V82AL24LI, L33FW6WL, L10V, I13V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, I72T, T91TSF
 RenG17487RenG17487KT748515PINAI54V, V82A, L90ML33FL10I, I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, L63A, I64M, C67S, T74S, L89M, I93LF
 RenG15729RenG15729KT746757PINAM46L, I54V, L76V, V82AL33FL5LF, W6L, L10V, I13V, K14R, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, G68D, L89IF
 RenG16739RenG16739KT747767PINAM46L, I54V, V82AL24I, L33F, T74PL10IV, I13V, K20R, E35D, M36I, N37D, R41K, K55T, R57K, Q61N, I64L, L89MF
 RenG16322RenG16322KT747350PINAI50L, L90ML33F, F53L, T74APL10V, T12TA, I13IV, I15S, G16R, K20R, E34N, E35D, M36I, P39T, R41K, K55KR, R57K, Q61N, L63T, A71AITV, I72T, V77VI, L89MF
 RenG17358RenG17358KT748386PINAM46L, I50V, I54IV, V82VAL33F, Q58EL10V, I13IV, I15V, L19I, K20R, E35D, M36I, R41K, K55R, R57K, I62V, L63P, T74S, L89MF
 RenG17240RenG17240KT748268PINAV32I, M46I, I47V, I54M, L90ML33F, F53L, L89VL10I, I13V, I15V, L19V, K20R, E35D, M36I, N37DE, R41K, G51A, R57K, Q61N, I66F, A71V, G73N, V77I, V82IF
 RenG16201RenG16201KT747229PINAM46L, I54V, V82A, L90ML33F, F53L, T74TPSL10IV, G16GA, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, Q61N, I62IV, L63A, I64M, A71V, Q92KF
 RenG16095RenG16095KT747123PINAM46L, I54V, V82AL33FL10E, L24K, M36I, N37D, R41K, R57K, Q61N, I62IV, L63P, H69Y, I72TF
 RenG17315RenG17315KT748343PINAM46I, I50L, V82A, N88NSL33F, F53LL10V, I13V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, H69Y, A71V, I72T, T74S, L89TF
 RenG17344RenG17344KT748372PINAM46I, I54V, L76V, V82A, L90ML33FL10V, T12I, I13V, G16E, K20R, E35D, M36I, N37T, R41K, R57K, D60E, Q61D, I62V, I72R, L89IF
 RenG15740RenG15740KT746768PINAM46I, V82AV32A, L33F, F53LL10I, I13V, G16E, K20R, E35D, M36L, R41K, Q61N, L63T, I66F, I72T, T74A, L89MF
 RenG14526RenG14526KT745554PINAD30N, M46I, I47V, I54V, V82A, L90ML33F, F53L, Q58E, N88DL10V, T12K, I15V, G16Q, K20T, E35S, M36I, P39S, R41K, K45R, R57K, D60E, Q61D, L63P, A71I, L89IF
 RenG14668RenG14668KT745696PINAD30N, I50L, V82A, L90ML33F, N88DI13V, I15V, K20R, E35D, M36I, R41K, K55N, R57K, Q61N, L63P, A71V, I72M, V77I, Q92QRF
 RenG14530RenG14530KT745558PINAI50L, V82AL33F, F53LL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, D60E, Q61DN, T74TA, V77I, L89MF
 RenG14639RenG14639KT745667PINAM46IL, G48A, I54A, V82AL24I, L33F, Q58EL10I, I13V, K20M, E35N, M36I, N37ND, F53FY, R57K, Q61N, I62IV, L63LP, L89M, Q92QKF
 RenG13828RenG13828KT744856PINAM46I, I47V, I54V, V82T, I84VL33F, K43T, F53L, T74PL10I, I13IV, K20R, E35D, M36I, N37ND, R41K, D60DE, Q61N, I62IV, L63P, A71V, Q92QRF
 RenG13750RenG13750KT744778PINAM46I, G48V, I50V, I54T, V82AL33FL10I, I15V, K20R, E34N, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, I85V, L89I, I93LF
 RenG14104RenG14104KT745132PINAG48M, V82S, I84VL24I, L33F, K43T, F53LL10V, I15IV, G16A, L19LV, K20R, E35D, M36I, N37K, R41K, R57K, D60E, Q61N, I62V, L63P, T74S, L89MF
 RenG13783RenG13783KT744811PINAM46I, I54V, V82A, L90ML33F, G73TL10I, I15V, K20R, E35D, M36I, N37ND, R41K, K55R, R57K, Q61N, L63P, V75IF
 RenG15499RenG15499KT746527PINAM46L, I50L, V82AL33FT12TS, I13IV, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, L89MF
 RenG13764RenG13764KT744792PINAM46I, I54V, V82AL24I, L33F, K43T, T74PL10V, T12P, I13V, I15V, Q18QL, L19P, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, I64L, H69R, I72R, L89M, Q92KF
 RenG14943RenG14943KT745971PINAG48V, I54V, V82A, L90ML33FL10IV, I13V, K14R, I15V, K20M, E35D, M36I, N37I, R41K, R57K, Q61N, T74S, L89I, Q92K, I93L, C95FF
 RenG13602RenG13602KT744630PINAI50L, V82A, L90ML33F, F53LL10V, I13V, I15V, K20R, E35D, M36I, N37D, R57K, Q61N, I62V, G68E, H69HY, A71V, I72T, L89IF
 RenG15231RenG15231KT746259PINAM46L, I50L, V82AL33F, K43TL10V, I15V, G16E, K20R, E35N, M36I, N37NT, P39S, R41K, I62V, L63T, I64V, E65D, A71V, I72T, T74S, I93LF
 RenG14761RenG14761KT745789PINAD30N, G48V, I54V, V82AL24I, L33F, F53LL10I, I13V, K14R, I15V, K20M, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, L89I, T91TS, Q92KF
 RenG14349RenG14349KT745377PINAM46I, I54V, V82AL24I, L33FL10V, T12A, I13V, G16E, Q18E, L19LP, K20T, E35D, M36L, R41K, R57K, Q61N, I64V, H69Q, A71V, I72R, I93LF
 RenG15319RenG15319KT746347PINAM46L, I54V, L76LV, V82AV11VI, L24I, L33F, F53FL, T74TPL10V, I13V, G16E, L19I, K20R, E35D, M36I, N37X, P39PS, R41K, K55R, R57K, Q61D, L63E, E65D, I72IR, L89MF
 RenG14684RenG14684KT745712PINAM46L, I54V, L76V, V82AL33FL10V, T12I, I13V, I15V, G16E, E35D, M36I, N37D, R57K, Q61N, L63T, E65D, I72T, T91SF
 RenG15176RenG15176KT746204PINAD30N, M46L, I50L, V82AL33FL10V, T12TM, I15V, G16E, K20R, E35D, M36V, P39S, R41K, K43Q, R57K, Q61N, L63T, I64V, E65D, A71V, I72T, V77I, I93LF
 RenG13655RenG13655KT744683PINAG48M, I54V, V82A, L90ML33F, F53L, T74PL10I, T12K, I13V, K14R, I15V, K20T, E35D, M36L, R41P, K55KR, R57K, Q61N, I62V, L63P, A71I, I72IV, V77I, L89TF
 RenG15255RenG15255KT746283PINAM46I, I47IV, I54IM, L90ML33F, F53FL, Q58EL10V, I15V, G16E, K20T, E35D, M36IV, P39S, K55R, R57K, Q61N, I62IV, L63T, I72T, T74S, L89MF
 RenG15172RenG15172KT746200PINAV32I, M46I, I47V, I54M, V82A, L90ML33F, F53L, T74PL10I, I13V, G16GDE, K20R, E34A, E35D, M36I, R41K, K45KR, K55R, R57K, Q61N, L63S, C67E, I72V, V77IF
 RenG14989RenG14989KT746017PINAI50L, V82AL33F, F53LI13V, I15V, K20R, E35D, M36I, N37IS, R41K, R57K, Q61N, L63T, I64L, K70Q, I72T, T74A, L89MF
 RenG14293RenG14293KT745321PINAM46L, I54V, L76V, V82AL33FL10V, I13V, G16E, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63V, E65D, I72T, T74A, L89MF
 RenG13694RenG13694KT744722PINAV32I, I47V, G48V, I54V, V82A, L90ML33F, F53L, Q58E, L89VL10I, I13V, K14E, I15V, K20R, E34Q, E35D, M36I, N37D, R41K, K55R, V56I, R57K, D60E, I62V, L63P, A71V, I85V, Q92KF
 RenG14011RenG14011KT745039PINAI54L, L76V, V82FL33F, Q58EL10V, T12I, I13V, I15V, G16E, K20R, E35D, M36I, P39T, R41K, R57K, Q61N, A71V, I72R, V77I, L89IM, I93LF
 RenG13850RenG13850KT744878PINAM46I, I54V, L76V, V82SL24I, L33F, Q58EL10I, I13V, L19I, K20M, E35N, M36I, N37E, K55R, R57K, D60E, Q61N, L63P, C67Q, K70R, I72V, L89MF
 RenG14160RenG14160KT745188PINAM46L, I54V, V82AL24I, L33F, Q58EL10I, K14T, L19Q, K20R, E35D, M36I, K55R, R57K, D60E, Q61N, I62V, L63P, E65D, I72IM, L89I, Q92KF
 RenG13721RenG13721KT744749PINAM46L, I50L, V82AL24I, L33FL10V, I13V, I15V, K20R, E35D, M36I, R41K, V56VA, R57K, Q61N, L63LP, E65ED, K70KR, L89MF
 RenG15368RenG15368KT746396PINAV32I, I47V, I50LL33F, G73SL10I, T12N, I15V, L19I, E35D, M36I, N37E, R57K, Q61N, I62V, L63A, I66L, Q92HF
 RenG15100RenG15100KT746128PINAM46I, I50V, I54V, V82AL33F, K43T, T74P, N83DL10I, I13V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, L89IF
 RenG15068RenG15068KT746096PINAI50L, V82AL33F, F53FLT12I, I13V, K14R, I15V, K20T, E35N, M36I, R41K, K55KR, R57K, Q61N, L63T, A71V, T74SF
 RenG15021RenG15021KT746049PINAM46L, I54LV, L76V, V82AL33FL10V, I13IV, G16E, L19V, K20R, E35D, M36I, N37DE, P39PQ, K55R, R57K, Q61N, L63T, E65D, I72V, T74S, L89MF
 RenG14069RenG14069KT745097PINAD30N, M46L, V82AL24I, L33F, K43TL10I, I15IV, G16E, K20R, E35D, M36V, N37T, P39S, R41K, R57K, Q61N, I62V, L63P, A71V, V75I, V77I, I93LF
 RenG15019RenG15019KT746047PINAI50L, V82L, N88SL33FI13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, I72T, T74A, L89MF
 RenG15072RenG15072KT746100PINAM46L, I54V, L76V, V82A, L90ML33F, Q58EL10V, I13V, K14R, G16E, K20R, E35D, M36I, N37E, P39S, R41RK, K55R, R57K, D60DE, Q61N, I62V, L63T, I64V, K70KT, V77IF
 RenG14428RenG14428KT745456PINAM46L, I54V, V82AL24I, L33F, T74PL10V, I13V, K20KR, E35D, M36I, N37D, R41K, R57K, Q61N, L89MF
 RenG14753RenG14753KT745781PINAM46I, I47V, I54V, V82AL24I, L33F, K43T, F53LL10I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63AV, I64IL, T74S, L89MF
 RenG14896RenG14896KT745924PINAM46I, I47V, I54V, V82FL33F, K43ITL10V, I13V, K20R, E35D, M36I, R41X, D60DE, Q61D, E65D, I72T, I85V, L89MF
 RenG14313RenG14313KT745341PINAM46L, I54V, V82AL10F, L33F, T74PI13V, K20I, E35D, M36I, R41K, K55R, R57K, Q61N, E65D, L89MF
 RenG12366RenG12366KT743394PINAM46I, I54V, V82AL24I, L33F, Q58EL10V, I13V, K20R, M36I, R41K, K55R, R57K, Q61N, L63P, A71T, I72T, T91SF
 RenG13393RenG13393KT744421PINAD30NL33F, F53L, N88DI15V, L19Q, K20T, E35D, M36I, N37NT, R41K, K45I, R57K, D60E, Q61E, I62V, L63P, I66F, A71V, T74S, V77I, V82I, L89T, Q92RF
 RenG12139RenG12139KT743167PINAV32VI, I47V, I54L, I84V, L90ML33F, K43KT, F53L, T74PL10I, I13V, K14KR, I15V, Q18QL, K20R, E35D, M36I, R41RK, R57RK, Q61QHKN, I62V, A71V, L89LFF
 RenG11893RenG11893KT742921PINAM46L, I50L, V82AL33FL10I, I13IV, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, L63P, C67D, A71AT, I72RF
 RenG11912RenG11912KT742940PINAI54L, I84V, L90ML33F, G73GCL10V, I13V, Q18H, L19I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, I72V, V77IF
 RenG13058RenG13058KT744086PINAM46I, I54A, V82M, L90ML33F, T74PL10I, I13V, K14R, I15V, K20R, E35D, M36I, N37DE, R41K, R57K, Q61N, L63T, I64V, H69S, L89MF
 RenG13456RenG13456KT744484PINAI50L, V82AL33F, F53LL10I, I13V, I15V, K20V, E35N, M36I, R41K, K43S, K55R, R57K, Q61N, L63P, H69HY, A71LV, T74SF
 RenG13532RenG13532KT744560PINAD30N, M46L, I54IV, V82A, L90ML33F, F53L, N88DL10V, T12Q, I13V, I15V, G16GE, K20R, E35D, M36I, R41K, K55KN, Q61N, L63S, I93ILF
 RenG12914RenG12914KT743942PINAI50L, V82VA, N88SL33FL10I, T12AE, I13V, K14KT, I15IV, K20V, E35N, M36I, N37E, K45R, R57K, Q61N, L63P, I64V, K70T, A71V, V77I, L89M, Q92QKF
 RenG13144RenG13144KT744172PINAM46L, I50L, V82AL33FK20R, E35D, M36I, N37I, R41K, K55KR, R57K, Q61D, T74S, L89M, I93ISF
 RenG12314RenG12314KT743342PINAD30N, I54LL33F, Q58QE, N88DR8P, L10V, I13V, I15V, K20T, T31A, E35D, M36I, K43R, R57K, Q61N, L63C, T74S, L89IMF
 RenG12665RenG12665KT743693PINAG48QR, I84V, L90ML33F, N83DL10V, K20R, E35D, M36L, R41K, R57K, Q61D, I62V, L63P, T74S, L89IF
 RenG12901RenG12901KT743929PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG12457RenG12457KT743485PINAV32I, M46I, I47V, I54ML33F, F53L, G73GSW6V, L10RT, I13IV, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, D60E, Q61D, L63P, A71V, I72IT, V77VI, L89TF
 RenG11965RenG11965KT742993PINAM46L, V82AL24I, L33F, K43T, I50M, G73ST12N, I13V, I15V, E35D, M36IL, R41K, R57K, Q61D, I62V, L63P, A71VF
 RenG12915RenG12915KT743943PINAM46I, I50L, V82AL33F, F53LK20R, E34N, E35D, M36I, R41K, K55R, R57K, Q61D, L63P, E65D, A71TF
 RenG12984RenG12984KT744012PINAM46I, I54V, V82A, I84V, L90ML33F, K43T, G73TL10V, L19V, K20R, E35D, M36I, R41N, D60E, Q61D, I62V, L63P, H69Y, A71T, I72TF
 RenG13420RenG13420KT744448PINAV82AV32A, L33FL10V, I13V, I15V, Q18E, K20R, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, E65D, A71V, I72V, L89I, I93LF
 RenG11967RenG11967KT742995PINAM46L, I54V, L76V, V82A, L90ML33F, Q58E, N83DL10I, I13V, G16E, K20R, E35N, M36I, R41K, K55R, R57K, Q61N, L63T, I72T, L89MF
 RenG12340RenG12340KT743368PINAM46L, I50L, V82VA, N88SL33FL10V, I13V, I15IV, G16E, K20R, E35D, M36I, N37S, P39P*QS, R41K, K45R, R57K, Q61N, L63S, I64IV, I72TF
 RenG12524RenG12524KT743552PINAG48A, I54V, L76V, V82A, I84VV11VI, L24I, L33F, K43T, M46V, F53L, N83DL10Y, L19I, K20R, E35N, M36I, N37D, K55R, R57K, D60E, Q61N, I62V, L63P, H69Y, A71V, I72K, L89I, T91A, Q92KF
 RenG12577RenG12577KT743605PINAM46MI, I47IV, I54V, V82A, L90ML33F, K43KT, F53LL10V, K20R, E35D, M36I, R57K, D60E, Q61N, I62V, L63P, I64V, A71V, I72T, V77I, I93LF
 RenG12374RenG12374KT743402PINAV32I, M46I, I54L, I84V, L90ML33F, L89VL10V, L19I, K20R, E35D, M36I, N37D, R41K, K55N, R57K, Q61N, A71V, Q92KF
 RenG12608RenG12608KT743636PINAI54V, V82A, L90ML33FL10V, I13V, I15V, K20T, E35D, M36IL, R41K, R57K, Q61N, I62IV, L63DE, A71T, I72T, L89IF
 RenG12550RenG12550KT743578PINAM46L, I54V, V82AL24I, L33F, K43T, F53LL10V, L19I, K20R, E35D, M36I, K55R, R57K, D60E, Q61E, I62V, L63P, A71V, I93LF
 RenG13387RenG13387KT744415PINAI50LL33F, F53LK20R, E34N, E35D, M36I, P39Q, R41K, R57K, Q61N, E65D, I72T, T74A, L89IMF
 RenG12493RenG12493KT743521PINAM46L, I54V, V82A, I84VL24I, L33F, K43KTL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, I64L, E65D, A71L, I72T, T91S, I93LF
 RenG12499RenG12499KT743527PINAM46I, I54V, L76V, V82AL33FL10I, T12I, I13V, I15V, G16E, K20*, D29V, E35D, M36I, N37DE, R41K, K55R, R57K, Q61N, I62R, L63V, E65ED, L89MF
 RenG12638RenG12638KT743666PINAI54V, V82A, L90ML33F, T74PL10V, I13V, K20R, E35D, M36I, R41K, R57K, Q61D, I72T, L89MF
 RenG11793RenG11793KT742821PINAG48A, I54V, V82AL24I, L33F, K43T, T74P, N83DL10I, I13V, K20R, E35D, M36L, R57K, Q61D, I62V, I72R, L89MF
 RenG11600RenG11600KT742628PINAM46I, I54L, V82A, I84VL24I, L33FL10I, I13V, I15V, K20R, E35D, M36I, R41K, K43I, R57K, Q61N, I62V, I72T, I85V, L89M, T91SF
 RenG10941RenG10941KT741969PINAM46L, I54V, V82AL24I, L33F, T74PL10I, I13IV, I15IK, K20R, E35D, M36I, R41RK, K43S, R57K, Q61N, I62V, L63P, I64M, A71V, L89LIM, I93LF
 RenG10140RenG10140KT741168PINAL90LML33F, F53L, N88TI13V, I15V, K20T, E35D, M36I, N37NT, R41K, K55R, R57K, Q61N, A71V, V77I, L89TF
 RenG10810RenG10810KT741838PINAM46L, I54V, V82AL24I, L33F, K43T, T74PW6L, L10V, I13V, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, I62V, I72T, L89MF
 RenG10406RenG10406KT741434PINAV32I, M46I, I54V, V82A, I84V, L90ML33F, G73CL10V, T12N, I13V, G16A, L19P, K20R, E34Q, E35D, M36I, R41K, F53I, K55R, R57K, Q61N, L63P, A71T, Q92KF
 RenG10321RenG10321KT741349PINAM46L, I50V, V82AV11I, L24I, L33F, K43T, F53FL, T74P, L89EIKVL10I, I13V, I15V, K20R, E35D, M36I, N37DE, R41K, R57K, Q61N, I62V, L63LP, G68GE, A71V, I93LF
 RenG10050RenG10050KT741078PINAM46I, I54V, L76V, V82AL33FL10V, I13V, K14R, K20KR, E35D, M36I, R41K, R57K, Q61N, L63P, E65D, K70R, L89MF
 RenG10018RenG10018KT741046PINAD30N, I54V, V82A, L90ML33F, N88DT12I, I13V, K14R, I15V, K20R, E35D, M36L, N37D, R41K, K45I, R57K, Q61N, I62V, L63P, G68E, H69R, I72IV, L89IF
 RenG10888RenG10888KT741916PINAM46I, I50V, I54V, V82AL24I, L33FL10V, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63P, T74A, L89MF
 RenG10261RenG10261KT741289PINAM46L, I50L, V82AL33FK20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I93LF
 RenG10136RenG10136KT741164PINAD30N, I50V, I54V, V82A, L90LML33F, N88DL10V, I13V, K20R, E35D, M36I, N37E, R41Y, K45Q, R57K, Q61N, L63ST, E65D, A71L, L89LM, I93LF
 RenG10230RenG10230KT741258PINAM46I, I50IVL33FI13IL, I15V, K20T, E35D, M36I, N37NHKQ, R41K, R57K, D60E, Q61NS, I62V, L63P, V82I, L89MF
 RenG11770RenG11770KT742798PINAM46I, V82F, L90ML33F, K43T, N88GL10IV, I13V, I15V, K20T, E35N, M36I, R57K, Q61D, L63P, A71L, I72T, V77I, L89I, I93LF
 RenG10032RenG10032KT741060PINAM46I, I54V, V82A, N88S, L90ML10F, L33F, Q58EI13V, G16E, K20T, E35D, M36I, P39PQ, R41K, R57K, Q61N, I62V, L63H, A71T, I72V, V77I, L89IF
 RenG10824RenG10824KT741852PINAV32I, M46I, I47V, I54M, V82A, L90MV11I, L33F, K43T, F53FLL10V, I13V, E34R, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, L89M, Q92RF
 RenG10083RenG10083KT741111PINAM46I, I50IL, V82AV32VA, L33F, N83NDL10V, T12E, I13V, I15IV, Q18QH, L19I, K20R, E35D, M36I, N37E, R41K, K55KN, R57K, Q61N, I62V, L63P, K70R, A71AV, T74S, V75IF
 RenG11711RenG11711KT742739PINAM46L, I54V, V82AL24I, L33F, K43T, G48E, F53LL10I, I15V, K20M, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, T74S, L89I, Q92KF
 RenG11573RenG11573KT742601PINAM46I, I50L, V82AL33F, F53LK20R, E34N, E35D, M36I, R41K, K55R, R57K, Q61D, L63P, E65D, A71TF