<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation L24I
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 95
Isolates 96
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Apetrei (2003)AC_Pat1RO.00.IS.01AY333462IDV, UnknownNAM46I, I54V, V82AL24I, K43TL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
  RO.01.IS.01AY333463IDV, Unknown, SQV, NFVNAM46I, I54V, V82A, I84VL24I, K43T, G48W, F53LL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89MF
de Sa Filho (2003)BREPM020BREPM020AY182788IDV M46I, I54V, V82AL24IL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L89MF
Soares (2003)BR60BR60AY275750IDV154M46I, I54V, V82TL24I, T74PL10I, T12E, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L89MF
Dumans (2004)RG070RG070AY390210IDV, RTV, Unknown>178M46I, I54V, V82SL24I, F53FL, Q58EL10I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, L63P, A71V, L89M, I93LF
Gomez-Carrillo (2004)9389593895AY365494PINAI54V, V82AL24IQ7QH, L10I, T12TN, K14I, I15V, G16GR, L19Q, K20R, T26TP, T31TP, E35D, M36I, R41K, K43KN, R57KN, Q61N, L63PF
 9480594805AY365504PINAI54V, V82AGL24IQ7QH, L10V, T12TP, K14R, I15V, K20R, E35D, M36I, R41K, K43KN, R57K, Q61D, A71VF
 9732297322AY365545PINAI54V, V82AL24I, K43T, F53LL10I, T12K, I15V, G16E, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72V, T74SF
 9746897468AY365549PINAM46L, I54V, V82AL24IQ7QH, L10V, T12E, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, T74SF
 9764497644AY365553PINAV32I, M46I, I47V, V82AL24I, L89VL10I, T12N, I15V, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, A71T, V77I, I93LF
 9824098240AY365571PINAM46I, I54V, V82AL24I, L33LF, K43T, F53L, N83DL10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, A71V, I93ILF
 9858898588AY365578PINAM46L, V82AL24IL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, E65D, I72T, T74S, L89MF
 9901099010AY365591PINAM46L, I54V, V82AL24IL10I, T12I, I15V, K20IMR, E35D, M36I, N37D, R41K, Q61D, L63P, I64V, H69Y, A71T, I72TF
 102704102704AY365658PINAM46I, I54V, V82TL24IL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, I72T, T74S, I93LF
 103279103279AY365676PINAM46I, I54S, V82AL24I, K43TL10I, T12P, I15V, L19I, K20M, E34K, E35D, M36I, R57K, Q61N, L63V, I64V, I72T, T74S, I85VF
 103828103828AY365686PINAM46L, I54V, V82AL24I, L33FL10V, T12S, I15V, L19IV, K20M, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, G73V, T74SF
 107559107559AY365770PINAM46L, I54V, V82A, I84VL24IL10I, I15V, G17E, E35D, M36I, N37D, R41K, R57K, D60E, Q61N, I62V, L63P, I64V, A71VF
 107858107858AY365777PINAM46I, I54V, V82AL24IL10I, I15V, K20M, E35D, M36V, P39T, R41K, K55R, R57K, Q61DN, L63PRST, A71V, I93LF
 114753114753AY365913PINAI54V, V82AL24IL10I, I15V, K20I, E35D, M36I, R41K, R57K, Q61D, A71V, I72RF
 116850116850AY365934PINAM46L, I54V, V82AL10F, L24I, L33F, G73CI15V, G16A, L19P, K20I, E35D, M36I, N37D, R41K, R57K, Q61N, L63PF
 120763120763AY365988PINAG48A, I54V, V82AL24I, F53LL10I, T12S, I15V, K20R, E35D, M36I, R41K, R57K, Q61D, T74S, L89MF
 120835120835AY365991PINAM46L, V82AL24IK14R, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, H69QF
 120879120879AY365992PINAM46I, I54V, V82AL24IL10V, T12E, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63V, T74SF
 120891120891AY365993PINAM46I, I50V, I54V, V82AL24I, L33FL10V, I15V, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, A71V, I72TF
 122494122494AY366012PINAM46I, I54V, V82AL24I, F53LL10I, I15V, G16E, K20R, E35D, M36I, R41K, K43I, K55R, R57K, Q61N, L63C, L89LMF
 124797124797AY366034PINAM46L, I54V, V82AL24I, L33F, G73CL10V, I15V, K20M, E35N, M36I, N37D, R41K, K55R, R57K, Q61D, A71V, I72TF
 126743126743AY366057PINAV32I, M46I, I47V, I54V, V82AL24I, L33F, F53LL10V, I15V, K20R, E34V, E35D, M36I, R41K, Q61N, I62V, L63P, T74S, L89M, Q92KF
Machado (2004)cs199cs199AY313361RTV75M46L, I54V, V82AL24IL10V, I15V, G16E, L19I, K20R, E35D, M36I, R57K, Q61D, L63V, E65DF
 cs133cs133AY313342RTV155M46L, I54V, V82AL24IL10I, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, L89MF
Non-B Workgroup (2005)PL882265161 SQV, IDV, LPV270G48M, I54V, V82AL24I, F53LL10I, T12I, I15V, G17E, K20M, E35D, M36IV, N37K, L38M, K43R, R57K, Q61N, L63PF
Rodrigues (2005)BR0274502AY643151IDV202I54V, V82AL24IL10I, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, T74S, L89MF
 BLF_Pat8BR03SP01AY643156Unknown, RTV, IDV>51M46L, I54A, V82AL24I, K43TL10I, I15V, L19I, K20R, E35D, M36I, K55R, R57K, Q61N, L63P, A71V, I85V, L89IF
 BLF_Pat22BR03SP87AY643178RTV, NFV, APV217M46L, I54V, V82AL24I, Q58EL10I, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, L63P, T74A, L89MF
Baxter (2006)48-10151015-30618DQ877259PINAM46MI, I54IV, V82AL24I, L33F, G73GCL10I, I15V, K20T, E35DN, M36I, R41K, K55R, R57K, Q61N, L63P, I93LF
 48-10161016-30617DQ877322PINAM46I, I54V, V82AL24I, F53LL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, H69Y, A71V, I93LF
 48-10081008-30625DQ877332PINAM46I, I50V, I54V, V82AL24I, L33FL10V, T12TN, I15V, E35D, M36I, R41K, R57K, Q61N, I62IV, L63P, A71V, I72TF
 48-10741074-30626DQ877334PINAV32I, M46I, I47V, I54V, V82A, L90LML24I, L33F, T74PSL10I, I13IV, I15IV, G16E, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63S, E65D, A71AV, V77I, L89M, Q92QK, I93LF
 48-10271027-30707DQ877408PINAV32I, M46I, I47V, I54V, V82AL24I, L33F, F53LL10V, I15V, K20R, E34V, E35D, M36I, R41K, Q61N, I62V, L63P, T74S, L89M, Q92KF
 48-12061206-30604DQ877750PINAM46L, I50V, I54V, V82AL24I, L33F, Q58EL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, I62V, L63Q, H69Y, L89MF
 48-12711271-30923DQ877792PINAG48V, I54V, V82SL24I, L33F, Q58EL10I, I15V, G16E, K20R, E34Q, E35D, M36I, P39PT, R41K, R57K, I62V, L63T, E65D, I72T, L89MF
 48-22512251-30925DQ877885PINAG48M, I54V, V82AL24I, F53L, G73GCFVL10I, T12I, I15V, G17E, K20M, E35D, M36I, K43R, R57K, Q61N, I62IV, L63P, T91TSF
 48-31113111-30725DQ878019PINAM46L, I54V, V82AL24I, L33FL10V, I15V, L19V, K20M, E35N, M36IL, R41K, R57K, Q61N, I62V, L63P, C67Y, G73V, T74SF
 48-32663266-30729DQ878171PINAM46I, I54V, V82AV11VI, L24I, L33F, L89VL10I, I15V, K20A, E35DN, M36L, N37Q, R41K, K55R, R57RK, D60E, Q61E, I62V, L63P, I64L, A71V, I72M, V77I, T91S, I93LF
 48-60236023-30403DQ878622PINAG48M, I54V, V82AL24I, K43KT, F53LL10I, I15V, Q18E, K20R, E35D, M36I, N37NK, R41K, R57K, Q61N, E65D, T74S, L89MF
 48-61196119-30924DQ878705PINAM46L, I54V, V82AL24IL10V, T12P, G17D, K20R, E35D, M36I, R57K, Q61N, L63S, I72T, L89MF
 48-91869186-30901DQ877291PINAM46L, I54V, V82AL24I, L33F, K43T, F53L, T74PL10I, I13V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I64L, A71V, I72T, L89I, I93LF
 48-92899289-30930DQ877308PINAM46L, I54V, V82A, I84IVL24I, L33LFL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63LP, A71V, L89M, Q92K, I93LF
 48-92509250-30908DQ877602PINAM46L, I54V, V82AV11VI, L24I, L33F, T74PL10I, I13V, G17E, L19I, K20R, E35D, M36I, R41K, R57K, Q61DN, I62V, L63T, E65D, I72T, L89MF
 48-91499149-30826DQ877714PINAM46L, I54V, V82AL24I, L33F, K43T, F53LR8P, L10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, K70R, L89LM, Q92KF
Dumans (2009)RENA578RENA578FJ405042IDV, SQV, RTV, NFV, LPV335M46I, I54A, V82AL24I, L33F, Q58EL10I, E35D, M36I, R41K, K55R, R57K, D60E, Q61N, I62V, L63A, L89MF
 RENA686RENA686FJ405043IDV, NFV326M46I, I54V, V82AL24I, K43T, T74PL10I, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63C, E65D, L89MF
 RES304_03RES304_03FJ405159IDV, NFV, LPV295M46L, I54V, V82AL24IL10I, K20R, A22AV, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, A71V, Q92KF
 59PR59PRFJ405165Unknown, NFV>27M46L, I54V, V82AL24IL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, I85V, L89MF
 RENA181RENA181FJ405173IDV213M46L, I54V, V82AL24IL10I, I15V, E35D, M36I, P39T, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71V, L89I, I93LF
Aulicino (2011)ARL449AMAARL449AMAFJ525809PINAM46I, I54V, V82SL24I, K43TL10I, I15V, K20R, E35D, M36I, R41RK, K55R, Q61N, L63P, T74S, Q92KF
 ARM36WMRARM36WMRFJ525826PINAM46I, I47V, I54V, V82AL24I, K43T, F53LL10V, G16X, K20R, E35D, M36I, K55R, R57K, Q61N, L63T, H69R, T74S, L89MF
 ARM616GGWARM616GGWFJ525834PINAM46L, I54V, V82AL24I, Q58ET4TA, L10V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61N, I64VF
 ARM730WDARM730WDFJ525838PINAI54V, V82AL24I, F53L, Q58E, N83DL10I, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, A71VF
 ARM896DNGARM896DNGFJ525845PINAM46I, I54L, L76V, V82AL24I, K43TL10I, T12P, I15V, G16E, L19P, K20R, E35D, M36I, N37D, K55R, R57K, Q61D, A71V, I72R, I93LF
 ARN156RJEARN156RJEFJ525852PINAD30N, M46I, I54V, V82AL24I, L33F, N83D, N88DL10I, K20R, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63D, A71V, I72PT, T74SF
 4460-L6744460-L674HQ158242PINAM46I, I54V, L76V, V82AL24I, K43TL10I, T12P, I15V, G16E, L19P, K20R, E35D, M36I, N37D, K55R, R57K, D60E, Q61D, A71V, I72R, I93LF
Jones (2012)128782128782JN669454PINAI54V, V82AL24I, K43TL10I, L19I, K20R, E35D, M36I, N37NH, R41K, R57K, Q61N, L63P, E65ED, A71V, I72T, T74S, V77VI, I93LF
 129410129410JN669469PINAM46L, I54V, V82AL24IL10I, I15V, L19I, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, A71V, I93LF
 131016131016JN669499PINAM46L, I54V, V82SL24IL10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, A71V, I72T, I93LF
 143027143027JN669634PINAG48A, I54V, V82AL24I, F53LL10I, T12S, K14R, I15V, K20R, E35D, M36I, N37D, R41K, R57K, Q61D, T74S, L89MF
 144353144353JN669648PINAV32I, M46MIV, I47IV, V82ML24I, K43KT, F53FLL10LI, I15V, G17D, K20R, E35D, M36I, R41K, R57K, Q61N, L63LP, I64IV, E65D, T74TAF
 151368151368JN669761PINAM46L, I54V, V82ML24I, K43TL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, E65D, I72T, I93IFF
 153756153756JN669805PINAM46L, G48GEQR, I54V, V82AL24I, F53LL10I, I15V, G17E, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71AVF
 153987153987JN669809PINAM46I, I54V, L76LV, V82AL24IL10I, I13IM, K20R, E35D, M36I, N37ND, R41K, K55KR, R57K, Q61N, L63P, I64L, A71V, L89IM, Q92K, I93LF
 155565155565JN669843PINAM46MI, I54V, V82ASL24I, G48GRL10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, L63LDHV, I72T, T74S, L89MF
 156299156299JN669858PINAM46L, I54V, V82SL24IL10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, A71V, I72T, I93LF
 159110159110JN669944PINAI54V, V82ML24I, K43TL10I, I15V, L19Q, K20R, E35D, M36V, R41K, R57K, Q61N, I62V, L63P, T74S, L89M, Q92KF
 161994161994JN670024PINAM46L, I54V, V82AL24I, K43KTL10V, I15V, G16E, L19I, K20R, M36I, K55R, R57K, Q61N, L63N, A71T, I72T, T91SF
 164492164492JN670077PINAM46L, I54V, V82AL24I, L33LF, K43KT, F53L, G73SL10V, K14R, I15V, L19LI, K20R, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, L63P, A71VF
 171023171023JN670243PINAM46L, I54V, V82AL24IL10V, I15V, E35D, M36I, R41K, K55R, R57K, Q61D, A71V, T74SF
 173500173500JN670335PINAM46L, I54V, V82AL24IL10V, I15V, G16E, L19I, K20R, M36I, K55R, R57K, Q61N, L63N, A71AT, I72IT, T91TSF
 178718178718JN670488PINAM46L, I54V, V82AL24I, F53LL10V, I15V, K20R, E35D, M36I, N37T, R41K, R57K, Q61N, L63P, C67EF
 181732181732JN670583PINAM46L, I54V, V82AL24I, L33F, G73CL10I, E35D, M36L, N37ND, R41K, K55R, R57K, Q61N, L63P, Q92KF
 181788181788JN670587PINAM46L, I54V, V82AL24IL10I, T12N, I15V, L19I, E35D, M36I, R41K, K55KR, Q61N, L63S, A71VF
 190134190134JN670789PINAI54V, V82SL24I, F53LL10I, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, A71VF
 191236191236JN670816PINAM46L, I54V, V82A, I84IVL24I, K43T, F53FLL10IV, I15V, G16E, L19I, K20R, E35D, M36I, K55R, R57K, Q61N, L63N, I64IV, A71T, I72T, T74TA, T91SF
 193837193837JN670913PINAM46L, I54V, V82AL24I, G73CL10I, I15V, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, I66IV, I93LF
 193990193990JN670919PINAM46L, I54V, V82A, I84VL24I, L33FL10I, I13V, I15V, K20M, E35D, M36I, R57K, Q61N, L63P, A71V, I72T, I93LF
 195789195789JN671000PINAM46I, I54V, V82AL24I, Q58EL10V, I15V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61DN, I62V, L63P, A71IV, I72IM, L89TF
 198666198666JN671128PINAM46I, I54V, V82AL24I, L89VI15V, G16E, K20M, E35D, M36I, R41K, K45R, R57K, Q61N, I72TF
 198678198678JN671129PINAM46L, G48Q, I54V, V82AL24I, F53LL10I, I15V, G17E, K20R, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61D, I62V, L63PF
 199882199882JN671185PINAM46L, I54V, V82AL24I, Q58EL10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, V77IF
 202293202293JN671265PINAM46L, I54V, V82AL24IL10I, I15V, K20R, E35D, M36I, N37E, R41K, R57K, Q61D, I62IV, L63T, T74TS, L89MF
 204162204162JN671328PINAG48MV, I54V, V82AL24I, K43T, F53FLL10V, I15V, K20R, E35D, M36I, N37D, R57K, Q61D, L63P, I72T, T91TAF
 204182204182JN671332PINAM46I, I50V, I54V, V82AL24I, L33FL10V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, C67CG, A71V, I72TF
 206165206165JN671393PINAM46L, I54V, I84VL24I, K43T, F53LL10I, I15V, G17D, K20T, E35N, M36I, K55R, Q61N, L63T, E65D, A71V, I72T, T74E, V82I, L89M, I93LF
 206166206166JN671394PINAM46L, I54V, V82AL24IL10I, I15V, A22V, E35D, M36I, R41K, K43R, R57K, Q61N, L63P, A71VF
 206318206318JN671397PINAM46L, I54V, V82A, I84VV11I, L24I, L33LF, K43TL10I, I15V, G16E, L19I, K20R, E35D, M36IV, K55R, R57K, Q61N, L63N, A71T, I72T, T91SF
 207306207306JN671430PINAM46L, I54V, V82AL24I, G48E, F53L, L89VL10I, I13IV, K20R, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, I64L, H69Y, A71V, Q92K, I93LF
 207640207640JN671442PINAM46L, G48AEKT, I54V, V82M, I84VL24I, L33I, K43T, F53FLL10I, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63IT, E65D, I72T, T74S, P79PS, L89MF
Grossman (2014)2727 LPV, SQV257G48M, I54V, V82AL24I, L33F, F53LL10I, I15V, Q18E, K20R, E35D, M36I, R41K, R57K, D60E, Q61D, I62V, L63P, I72V, V75IF