<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation K20M
Rx PI-naive
IncludeMixtures No
References 14
Patients 17
Isolates 17
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Servais (2001)JS97287JS97287AJ012427None   L10I, T12N, I15V, K20M, E35D, M36I, P39Q, R41K, R57K, Q61N, L63I, I72T, L89M, I93LF
Thomson (2002)A027A027AF332867None   I13V, I15V, L19I, K20M, E35D, M36I, R41K, R57K, Q61N, I72T, I93LF
Espinosa (2004)11AY140108None   I15A, K20M, E35D, M36I, R41K, R57K, Q61D, L63P, I93LF
 5353AY140147None   Q7P, I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63Q, E65D, I93LF
Petroni (2006)AP_ARRP013AP_ARRP013DQ206652None   T12E, K14R, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, L63GF
Dilernia (2007)F069F069EF120119None   I15V, G17E, K20M, E35D, M36I, R41K, R57K, Q61N, I93LF
 F143F143EF120145None   T12P, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, E65D, I72T, L97IF
 F376F376EF120252None   I15V, G16E, K20M, E35D, M36I, P39T, R41K, R57K, Q61N, I93LF
Paraschiv (2007)36103610_2003JQ083000None   T12S, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61H, L63T, E65D, L89MF
Cardoso (2009)BRGO3140BRGO3140FJ594174None   I13V, I15V, K20M, E35D, M36I, N37K, P39T, R41K, K45R, R57K, D60E, Q61D, L63P, V82VI, L89MF
Castillo (2009)6868PROTGQ202940None  L33LIT12A, I13V, K14R, K20M, E35D, M36I, R41RK, R57RK, L63LP, H69HKNQ, L89MF
Yebra (2010)17381604SP0173816FJ481671None   I15V, K20M, E35D, M36I, R41K, R57K, Q61N, I93LF
Ferreira (2011)BRMT323BRMT323HQ638751None   L10V, I13V, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, E65D, I72T, L89MF
Florea (2011)502_2007502_2007JQ083076None   I13V, I15V, G16E, K20M, E35DN, M36I, N37ND, R41K, R57K, L63N, E65D, L89MF
Graf (2011)SC37SC37JF774004None   I13V, I15V, G17E, L19I, K20M, E35D, M36I, R57K, Q61N, L63A, I64M, I93LF
da Silveira (2012)BRMS04_10BRMS04_10JF342315None   K14R, I15V, G17E, L19I, K20M, E35D, M36I, R41K, R57K, Q61N, L63LF, E65D, I72IATVF
Alencar (2013)PE2-0087PE2-0087JQ238226None   T12A, I13V, K14R, I15V, K20M, E35D, M36I, P39Q, R57K, D60E, Q61D, L63P, L89MF

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