<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation K20M
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 41
Isolates 41
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)109902109902AY365826PINA  I15V, G16E, K20M, E35D, M36I, R41K, K43R, R57K, Q61N, I72TF
Non-B Workgroup (2005)PL36995591 Unknown, LPV>112M46L, G48V, I54V, V82A, L90ML33F, K43TL10V, I15V, G16E, K20M, E35N, M36I, N37ND, R57K, Q61D, G68E, H69R, A71T, I72R, L89I, I93LF
 PL3749895930 IDV, LPV197  I15V, G17D, K20M, E35D, M36I, R57K, Q61H, L89MF
Baxter (2006)48-90259025-30825DQ877501PINAM46I, I54S, V82AL33FL10I, I13V, I15V, K20M, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, T74S, L89IF
 48-92789278-30924DQ877616PINAM46I, I47V, I54L, V82A, L90MK43T, F53L, G73C, L89VL10V, I15V, G16E, Q18H, K20M, E34Q, M36I, P39S, K55R, D60E, I62V, L63P, I85VF
Sanabani (2006)02BR03402BR034DQ358812PINAL90M G16E, K20M, E35D, M36V, R41K, K43R, R57K, Q61N, L89MF
Waleria-Aleixo (2008)08PR06054608PR060546FJ591462PINAI54V, V82A, L90MF53LL10V, T12I, I15V, G16E, K20M, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, I66M, K70KR, A71T, I72T, I85V, L89I, Q92K, C95VF
 08RJ06048508RJ060485FJ591678PINA  I15V, K20M, E35D, M36I, R41K, L63PF
Jones (2012)146813146813JN669682PINAI54V, V82A, L90M L10I, T12TP, I15V, Q18K, K20M, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, T74A, V75VA, L89MF
 155316155316JN669839PINA  I15V, K20M, E35N, M36I, R41RK, R57K, Q61D, L63LP, I72T, T74TS, Q92QRF
 157610157610JN669893PINA  L10I, T12K, I15V, K20M, E35D, M36I, R41K, R57K, Q61D, I62V, L63H, I93LF
 164777164777JN670081PINAI54V, V82A, L90ML33F, G73SL10I, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, A71T, I72RF
 170719170719JN670232PINAI54V, V82A, L90ML33IL10I, I13V, K14R, K20M, E35D, M36I, N37D, R41K, Q61N, L63P, A71T, I72TF
 183130183130JN670639PINA  I15V, K20M, E35D, M36I, R41K, R57K, D60E, Q61D, I72TF
 183349183349JN670642PINAM46L, I54V, L76V, V82A L10I, T12I, I15V, G16E, L19I, K20M, E35DN, M36I, R41RK, R57K, Q61N, L63LH, I85V, L89IF
 190338190338JN670794PINA  I15V, G17E, K20M, E35D, M36I, R41K, K43R, R57K, Q61NF
 195689195689JN670995PINA  I15V, G16E, Q18K, K20M, E35D, M36I, R41K, R57K, Q61S, T74A, L89MF
 197265197265JN671068PINA  T12A, K14R, I15V, G16E, Q18L, K20M, E35D, M36I, R41K, R57K, Q61N, I72T, L89MF
 198666198666JN671128PINAM46I, I54V, V82AL24I, L89VI15V, G16E, K20M, E35D, M36I, R41K, K45R, R57K, Q61N, I72TF
 205791205791JN671372PINAI54V, I84V, L90M L10I, I13IV, I15V, Q18K, K20M, E35D, M36I, R41K, Q61N, I62V, L63P, I66IV, T74A, L89IF
Diaz (2015)RenG15561RenG15561KT746589PINAI50L, N88NS, L90LML33LF, T74TPL10V, K20M, E35G, M36I, R41K, R57K, Q61N, L63P, K70R, A71IV, L89M, I93LF
 RenG16639RenG16639KT747667PINAM46I, I54LV, I84V, L90ML33LFL10I, T12E, I13V, K20M, M36I, R57K, Q61N, L63P, I66F, C67Y, A71T, Q92R, I93L, C95FF
 RenG16017RenG16017KT747045PINA T74PI13V, K14R, I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63PF
 RenG16257RenG16257KT747285PINAM46I, I54V, L76V, V82AL24IL10I, I13V, K20M, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63P, A71T, I72T, T74S, L89IF
 RenG16325RenG16325KT747353PINA  K14KR, I15L, Q18QK, K20M, E35D, M36I, R41K, R57K, Q61N, V77IF
 RenG14503RenG14503KT745531PINAM46I, I50V, I54V, V82A L10I, T12K, I13V, K14R, L19P, K20M, E35D, M36I, R41K, R57K, Q61N, I62IV, I64IV, T74S, L89IF
 RenG14639RenG14639KT745667PINAM46IL, G48A, I54A, V82AL24I, L33F, Q58EL10I, I13V, K20M, E35N, M36I, N37ND, F53FY, R57K, Q61N, I62IV, L63LP, L89M, Q92QKF
 RenG14943RenG14943KT745971PINAG48V, I54V, V82A, L90ML33FL10IV, I13V, K14R, I15V, K20M, E35D, M36I, N37I, R41K, R57K, Q61N, T74S, L89I, Q92K, I93L, C95FF
 RenG14761RenG14761KT745789PINAD30N, G48V, I54V, V82AL24I, L33F, F53LL10I, I13V, K14R, I15V, K20M, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, L89I, T91TS, Q92KF
 RenG15104RenG15104KT746132PINAG48V, I54V, V82A, L90ML33LFL10I, I13V, K14R, I15V, K20M, E35D, M36I, N37NIK, R41K, R57K, Q61N, T74S, L89I, Q92K, I93L, C95FF
 RenG14867RenG14867KT745895PINAM46I, I47AL10F, L33LI, F53LT12I, I13V, I15V, Q18E, K20M, E35N, M36I, R41K, K45R, R57K, Q61N, L89IF
 RenG13850RenG13850KT744878PINAM46I, I54V, L76V, V82SL24I, L33F, Q58EL10I, I13V, L19I, K20M, E35N, M36I, N37E, K55R, R57K, D60E, Q61N, L63P, C67Q, K70R, I72V, L89MF
 RenG13889RenG13889KT744917PINAG48V, I54T, V82AK43KTL10I, T12S, I13V, K20M, E35D, M36I, R41K, R57K, Q61N, T74S, L89I, N98K, F99FLF
 RenG14675RenG14675KT745703PINAM46L, I50IL, I54V, V82AV11I, L24I, F53FL, L89LMVL10I, I15V, L19LAPV, K20M, E35N, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, A71IV, I72T, Q92KF
 RenG11988RenG11988KT743016PINAI54V, V82A L10V, T12I, I13V, I15IV, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, I72T, L89IF
 RenG12756RenG12756KT743784PINA  T12TK, I15V, G16E, K20M, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, L63X, I72E, V77I, L89M, I93LF
 RenG12196RenG12196KT743224PINAI54IV, V82A, L90M I15V, G16E, K20M, E35N, M36I, N37D, G40R, R41K, R57K, Q61N, K70R, L89I, L97*F
 RenG11642RenG11642KT742670PINA  G16E, K20M, E35D, M36I, R57K, Q61N, L63A, I72TF
 RenG11470RenG11470KT742498PINAI54V, V82A, L90M L10I, I13V, K20M, L33L_L, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, A71T, L89I, Q92KF
 RenG11198RenG11198KT742226PINA Q58EL10I, K20M, E35D, M36I, R41K, R57K, Q61N, L63T, I72V, L89M, I93LF
 RenG11711RenG11711KT742739PINAM46L, I54V, V82AL24I, L33F, K43T, G48E, F53LL10I, I15V, K20M, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, T74S, L89I, Q92KF