<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation K20M
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 102
Isolates 102
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)9138591385AY365471PINAI54V, V82A L10I, I15V, G16E, K20M, E35N, M36I, R41K, R57K, D60E, Q61D, I72RF
 100161100161AY365609PINA  I15V, G16GE, K20M, E35D, M36I, R41K, R57K, D60E, Q61D, L63S, K70KR, I72TF
 101490101490AY365638PINAM46I, I54V, V82VA, L90M L10I, I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I72T, V77VI, I93LF
 103279103279AY365676PINAM46I, I54S, V82AL24I, K43TL10I, T12P, I15V, L19I, K20M, E34K, E35D, M36I, R57K, Q61N, L63V, I64V, I72T, T74S, I85VF
 103828103828AY365686PINAM46L, I54V, V82AL24I, L33FL10V, T12S, I15V, L19IV, K20M, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, G73V, T74SF
 106151106151AY365743PINAI84V, L90MG73SI15V, K20M, E35D, M36I, R41K, R57K, Q61D, A71V, I72R, I93LF
 107858107858AY365777PINAM46I, I54V, V82AL24IL10I, I15V, K20M, E35D, M36V, P39T, R41K, K55R, R57K, Q61DN, L63PRST, A71V, I93LF
 109559109559AY365823PINA  L10I, I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63A, V82I, L89M, I93LF
 109902109902AY365826PINA  I15V, G16E, K20M, E35D, M36I, R41K, K43R, R57K, Q61N, I72TF
 110439110439AY365837PINAI54V, V82AG73SL10I, I15V, K20M, E35D, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, I93LF
 111896111896AY365854PINA  I15V, K20M, E35D, M36I, R41K, R57K, D60E, Q61D, I62IV, I93LF
 116065116065AY365927PINAI54V, V82A, L90ML33FI13V, I15V, K20M, E35N, M36I, R41K, R57K, Q61N, I62V, L63P, H69R, A71V, T74SF
 116066116066AY365928PINAV82A, L90M L10I, T12A, I15V, G17D, K20M, E35D, M36I, R41K, R57K, D60E, Q61D, L63P, A71V, I93LF
 119804119804AY365974PINAM46L, G48V, I54V, L76V, V82A, L90ML33F, K43TL10I, I15V, G16E, K20M, E35H, M36L, R41K, K55R, R57K, Q61N, L63S, E65D, A71V, T74S, I93LF
 122345122345AY366009PINAG48V, V82AF53LL10V, I15V, G16E, K20M, E35D, M36I, P39Q, R41K, K55R, R57K, Q61N, L63T, T74AF
 124797124797AY366034PINAM46L, I54V, V82AL24I, L33F, G73CL10V, I15V, K20M, E35N, M36I, N37D, R41K, K55R, R57K, Q61D, A71V, I72TF
 125545125545AY366048PINAI54IV, L90M T4TA, Q7QH, I15V, K20M, E35D, M36IV, R41K, R57K, Q61N, L63A, I93LF
Non-B Workgroup (2005)PL36995591 Unknown, LPV>112M46L, G48V, I54V, V82A, L90ML33F, K43TL10V, I15V, G16E, K20M, E35N, M36I, N37ND, R57K, Q61D, G68E, H69R, A71T, I72R, L89I, I93LF
 PL3749895930 IDV, LPV197  I15V, G17D, K20M, E35D, M36I, R57K, Q61H, L89MF
 PL882265161 SQV, IDV, LPV270G48M, I54V, V82AL24I, F53LL10I, T12I, I15V, G17E, K20M, E35D, M36IV, N37K, L38M, K43R, R57K, Q61N, L63PF
Baxter (2006)48-10381038-30619DQ877393PINAI54V, V82A L10LI, T12S, I15V, L19LF, K20M, E35D, M36I, R41K, Q61N, L63A, A71AITVF
 48-11031103-30708DQ877410PINAM46L, I54V, L76V, V82A, L90ML33F, K43TL10I, I13V, I15V, G16E, K20M, E35H, M36L, R41K_K, K55R, R57K, Q61N, L63S, E65D, A71V, T74S, L89LM, I93LF
 48-22512251-30925DQ877885PINAG48M, I54V, V82AL24I, F53L, G73GCFVL10I, T12I, I15V, G17E, K20M, E35D, M36I, K43R, R57K, Q61N, I62IV, L63P, T91TSF
 48-31113111-30725DQ878019PINAM46L, I54V, V82AL24I, L33FL10V, I15V, L19V, K20M, E35N, M36IL, R41K, R57K, Q61N, I62V, L63P, C67Y, G73V, T74SF
 48-90259025-30825DQ877501PINAM46I, I54S, V82AL33FL10I, I13V, I15V, K20M, E35N, M36I, N37D, R41K, K55R, R57K, Q61N, T74S, L89IF
Sanabani (2006)02BR03402BR034DQ358812PINAL90M G16E, K20M, E35D, M36V, R41K, K43R, R57K, Q61N, L89MF
Dumans (2009)12SP04076012SP040760FJ405044IDV, RTV318M46L, V82A T12Q, I15V, Q18L, L19P, K20M, E35D, M36I, R57K, Q61N, L63P, I64V, T74S, I93LF
Aulicino (2011)ARM512NYNARM512NYNFJ525831PINA  T12A, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, I72TF
 ARM674VJARM674VJFJ525837PINA  I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63P, C67H, H69C, I93LF
 59-O184CME59-O184CMEHQ158162PINA  I15V, K20M, E35D, M36I, R41K, R57K, Q61D, A71T, I72T, I93LF
 3121-O269FJN3121-O269FJNHQ158163PINA  T12E, K14R, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, I72S, L89MF
 4390-L8394390-L839HQ158238PINA  T12N, I15V, K20M, E35D, M36I, R41K, R57K, Q61S, I93LF
Jones (2012)108395108395JN669427PINA  K14R, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, I93LF
 141434141434JN669601PINA  T12TA, K14R, I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63G, I93LF
 142194142194JN669614PINAD30NK43KT, N88NDI15V, G16GE, K20M, E35G, M36I, R41K, R57K, Q61N, L63G, I93LF
 143569143569JN669642PINAM46I, I84V, L90ML10LFI, G73ST12M, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61D, I62V, I72K, I93LF
 145632145632JN669660PINA  I15V, K20M, E35D, M36I, R41K, R57K, Q61N, I93LF
 146813146813JN669682PINAI54V, V82A, L90M L10I, T12TP, I15V, Q18K, K20M, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, T74A, V75VA, L89MF
 153757153757JN669806PINAM46L, I54V, V82AK43TL10I, I15V, G17E, K20M, E35D, M36I, N37K, R57K, Q61D, L63P, I72R, I85V, I93LF
 154695154695JN669824PINA  T12E, K14R, I15V, K20M, E35D, M36I, R57K, Q61N, I72TF
 155316155316JN669839PINA  I15V, K20M, E35N, M36I, R41RK, R57K, Q61D, L63LP, I72T, T74TS, Q92QRF
 158327158327JN669910PINA  I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63Q, E65D, H69Y, I72TF
 159510159510JN669955PINAI54V, V82A, L90MK43TL10I, I15V, G16E, K20M, E35D, M36I, R41R_R, R57K, Q61N, I62L, L63C, A71T, I72T, T74S, I85VF
 163316163316JN670061PINAM46L, I54V, V82A, L90ML33F, G73SL10I, I15V, G16E, K20M, E35N, M36I, R41K, K55R, R57K, Q61N, A71I, I72T, I93LF
 164777164777JN670081PINAI54V, V82A, L90ML33F, G73SL10I, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, A71T, I72RF
 166909166909JN670138PINAI54IV, V82VA, L90MG73GSL10I, T12TA, I13IL, K14R, I15V, G16A, K20M, E35D, M36I, R41K, W42W*, R57K, Q61N, L63P, A71AITV, I72T, I93LF
 171375171375JN670258PINAI54V, V82AL24LIL10V, I15V, K20M, E35D, M36I, N37D, R41K, K43R, K45KR, R57K, Q61N, H69Y, A71AV, I72TF
 172335172335JN670285PINAG48V, I54V, V82AT, L90MF53FL, G73GSL10V, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61DN, A71V, I72R, I93LF
 173324173324JN670324PINA  V11VL, I15V, G16GE, K20M, A22AT, D25DV, T26TA, E35D, M36I, R41K, R57K, Q61N, L63A, I93ILF
 176204176204JN670389PINA  K14R, I15V, G17D, K20M, E35D, M36I, R41K, R57K, Q61N, I72IM, I93LF
 176630176630JN670406PINAL90M I15V, K20M, E35D, M36V, R41K, R57K, Q61N, I62IV, L63A, I93LF
 180983180983JN670563PINA  I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63H, I93LF
 183130183130JN670639PINA  I15V, K20M, E35D, M36I, R41K, R57K, D60E, Q61D, I72TF
 183349183349JN670642PINAM46L, I54V, L76V, V82A L10I, T12I, I15V, G16E, L19I, K20M, E35DN, M36I, R41RK, R57K, Q61N, L63LH, I85V, L89IF
 183430183430JN670647PINA  T12TA, I15V, K20M, E35D, M36I, N37D, R41K, R57K, Q61N, L63A, I93LF
 183504183504JN670649PINAM46I, I54V, V82A, L90ML33F, K43KT, F53L, T74PL10V, I15V, K20M, E35N, M36L, N37ND, L38W, R41K, K55R, R57K, Q61N, I62V, L63P, H69R, A71V, I72V, I93LF
 189562189562JN670776PINAI54V, V82A, L90M L10I, T12P, K14R, I15V, G16E, K20M, E35N, M36I, N37E, P39Q, R41K, R57K, D60E, Q61D, I62V, A71V, I72T, I93LF
 189917189917JN670784PINA  T12E, K14R, I15V, K20M, E35D, M36I, R41K, K43KR, R57K, Q61N, L63GF
 190055190055JN670787PINAL90M I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, I93LF
 190338190338JN670794PINA  I15V, G17E, K20M, E35D, M36I, R41K, K43R, R57K, Q61NF
 191506191506JN670828PINA  K14R, I15V, K20M, E35D, M36I, R41K, G49R, R57K, Q61DNF
 191810191810JN670836PINA  L19LP, K20M, E35D, M36I, R41K, R57K, Q61N, I93LF
 193358193358JN670894PINAL90M L10LI, T12N, I15V, K20M, E35D, M36I, R41K, R57K, D60E, Q61D, L63T, I72T, T74AF
 193990193990JN670919PINAM46L, I54V, V82A, I84VL24I, L33FL10I, I13V, I15V, K20M, E35D, M36I, R57K, Q61N, L63P, A71V, I72T, I93LF
 195689195689JN670995PINA  I15V, G16E, Q18K, K20M, E35D, M36I, R41K, R57K, Q61S, T74A, L89MF
 196051196051JN671009PINA  I15V, K20M, E35D, M36I, R41K, R57K, Q61N, I72EF
 196312196312JN671019PINA  T12AE, K14R, I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63G, I93ILF
 197265197265JN671068PINA  T12A, K14R, I15V, G16E, Q18L, K20M, E35D, M36I, R41K, R57K, Q61N, I72T, L89MF
 198666198666JN671128PINAM46I, I54V, V82AL24I, L89VI15V, G16E, K20M, E35D, M36I, R41K, K45R, R57K, Q61N, I72TF
 198783198783JN671134PINAV82A L10LV, K14KR, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, I72TF
 199262199262JN671157PINA  K14R, I15V, Q18E, K20M, E35D, M36I, R41K, R57RK, Q61N, L63LP, I93ILF
 199593199593JN671177PINA  L10V, T12E, I13V, K14R, I15V, G16E, K20M, E35D, M36I, R41K, R57RK, Q61N, I72TF
 205495205495JN671363PINAI54V, V82A L10I, I15V, K20M, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, I93LF
 205530205530JN671366PINAI54V, V82T L10I, I15V, K20M, E35D, M36I, R41K, K45R, R57K, Q61N, L63P, T74S, I85V, I93LF
 205791205791JN671372PINAI54V, I84V, L90M L10I, I13IV, I15V, Q18K, K20M, E35D, M36I, R41K, Q61N, I62V, L63P, I66IV, T74A, L89IF
 207465207465JN671433PINA  I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, E65D, I72TF
Diaz (2015)RenG17098RenG17098KT748126PINA  I15V, K20M, E35D, M36I, R41K, R57K, Q61N, I64M, I93LF
 RenG15561RenG15561KT746589PINAI50L, N88NS, L90LML33LF, T74TPL10V, K20M, E35G, M36I, R41K, R57K, Q61N, L63P, K70R, A71IV, L89M, I93LF
 RenG16017RenG16017KT747045PINA T74PI13V, K14R, I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63PF
 RenG16136RenG16136KT747164PINAL90M L10V, I15V, K20M, E35D, M36I, R41K, R57K, Q61N, I62IV, L63S, I64V, C67S, I72TF
 RenG15577RenG15577KT746605PINA  I15V, K20M, E35D, M36I, R41K, R57K, Q61N, I93LF
 RenG16325RenG16325KT747353PINA  K14KR, I15L, Q18QK, K20M, E35D, M36I, R41K, R57K, Q61N, V77IF
 RenG14903RenG14903KT745931PINAM46I, I47V, I54V, V82AF53LL10I, I15V, G16E, K20M, E35D, M36V, R57K, Q61N, E65D, A71V, I72T, I93LF
 RenG14503RenG14503KT745531PINAM46I, I50V, I54V, V82A L10I, T12K, I13V, K14R, L19P, K20M, E35D, M36I, R41K, R57K, Q61N, I62IV, I64IV, T74S, L89IF
 RenG13788RenG13788KT744816PINA  T12P, K14R, I15V, G16E, K20M, E35D, M36I, R41K, K45R, Q61N, I64IV, I72T, I93LF
 RenG14943RenG14943KT745971PINAG48V, I54V, V82A, L90ML33FL10IV, I13V, K14R, I15V, K20M, E35D, M36I, N37I, R41K, R57K, Q61N, T74S, L89I, Q92K, I93L, C95FF
 RenG14761RenG14761KT745789PINAD30N, G48V, I54V, V82AL24I, L33F, F53LL10I, I13V, K14R, I15V, K20M, E35D, M36I, N37D, R41K, R57K, Q61N, T74S, L89I, T91TS, Q92KF
 RenG15104RenG15104KT746132PINAG48V, I54V, V82A, L90ML33LFL10I, I13V, K14R, I15V, K20M, E35D, M36I, N37NIK, R41K, R57K, Q61N, T74S, L89I, Q92K, I93L, C95FF
 RenG14867RenG14867KT745895PINAM46I, I47AL10F, L33LI, F53LT12I, I13V, I15V, Q18E, K20M, E35N, M36I, R41K, K45R, R57K, Q61N, L89IF
 RenG13850RenG13850KT744878PINAM46I, I54V, L76V, V82SL24I, L33F, Q58EL10I, I13V, L19I, K20M, E35N, M36I, N37E, K55R, R57K, D60E, Q61N, L63P, C67Q, K70R, I72V, L89MF
 RenG13883RenG13883KT744911PINA  I15V, G17D, Q18QR, L19X, K20M, E35D, M36I, R57K, Q61N, L63A, I64IV, I93ILF
 RenG11988RenG11988KT743016PINAI54V, V82A L10V, T12I, I13V, I15IV, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, I72T, L89IF
 RenG12469RenG12469KT743497PINA  I15V, K20M, E35D, M36I, R41K, R57K, Q61N, I64M, I93LF
 RenG13246RenG13246KT744274PINAD30N, M46MI, V82VAL33LF, N88DL10V, T12S, I15V, G16E, K20M, E35DN, M36I, R57K, Q61N, L63S, E65DF
 RenG12756RenG12756KT743784PINA  T12TK, I15V, G16E, K20M, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, L63X, I72E, V77I, L89M, I93LF
 RenG12196RenG12196KT743224PINAI54IV, V82A, L90M I15V, G16E, K20M, E35N, M36I, N37D, G40R, R41K, R57K, Q61N, K70R, L89I, L97*F
 RenG11642RenG11642KT742670PINA  G16E, K20M, E35D, M36I, R57K, Q61N, L63A, I72TF
 RenG10843RenG10843KT741871PINA  T12S, I15V, G16E, K20M, E35D, M36I, R57K, Q61N, L63S, E65D, I72ITF
 RenG11470RenG11470KT742498PINAI54V, V82A, L90M L10I, I13V, K20M, L33L_L, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, A71T, L89I, Q92KF
 RenG11198RenG11198KT742226PINA Q58EL10I, K20M, E35D, M36I, R41K, R57K, Q61N, L63T, I72V, L89M, I93LF
 RenG11711RenG11711KT742739PINAM46L, I54V, V82AL24I, L33F, K43T, G48E, F53LL10I, I15V, K20M, E35D, M36I, R41K, K55R, R57K, Q61N, I62V, T74S, L89I, Q92KF
 RenG11444RenG11444KT742472PINA  T12S, I15V, G16E, K20M, E35D, M36I, R57K, Q61N, L63S, E65DF