<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation K20I
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 41
Isolates 41
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)100837100837AY365622PINAI54V, V82A, L90M L10I, T12K, I15V, L19I, K20I, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, T74SF
 105247105247AY365720PINAI54V, V82A, L90M L10I, T12N, I15V, K20I, E35D, M36I, R41K, K45R, R57K, Q61N, L63A, E65D, A71V, I85V, I93LF
 109072109072AY365802PINAM46I, I84V, L90M L10I, I13V, I15V, Q18H, L19I, K20I, E35D, M36I, N37K, R41K, R57K, D60DE, Q61N, L63P, G68E, A71T, I72EF
 113771113771AY365884PINAI47V, I54M, L90M L10I, I13IV, I15V, K20I, E35DN, M36I, R41K, R57K, Q61N, L63P, T74S, V82VI, I85VF
 114753114753AY365913PINAI54V, V82AL24IL10I, I15V, K20I, E35D, M36I, R41K, R57K, Q61D, A71V, I72RF
 116850116850AY365934PINAM46L, I54V, V82AL10F, L24I, L33F, G73CI15V, G16A, L19P, K20I, E35D, M36I, N37D, R41K, R57K, Q61N, L63PF
 118746118746AY365953PINAM46I, I54V, I84V, L90MV11I, G73SL10I, I15V, L19P, K20I, E35D, M36I, R57K, Q61H, L63P, A71V, I72T, I85V, I93LF
Rodrigues (2005)BLF_Pat5BR03SP147AY643162Unknown, IDV>256I54V, V82A L10I, I13V, I15V, G17E, K20I, E35D, M36I, R41K, R57K, Q61N, L63R, E65D, T74S, L89IF
 BLF_Pat12BR03SP110AY643158IDV, NFV271L90M L10I, I15L, L19I, K20I, E35D, M36I, N37S, R41K, R57K, Q61N, L63P, I64V, A71T, I72T, I93LF
Baxter (2006)48-10551055-30707DQ877421PINAM46I, I47V, I54V, V82F, L90MF53FLL10I, K20I, E35D, M36V, R41K, R57K, Q61N, I62IV, L63Q, I64IV, A71V, T74S, I93LF
 48-11801180-30922DQ877428PINAV32I, M46I, I47V, I54M, L90MF53LL10I, I15V, K20I, E35N, M36I, R41K, R57K, Q61N, L63P, I72IV, T74S, V82I, I85V, L89LIF
Dumans (2009)RENA395RENA395FJ405051IDV, RTV200L76VL89VK20I, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, I93LF
Aulicino (2011)ARL162MJMARL162MJMFJ525806PINAM46L, I54V, V82A, L90M L10I, I15V, K20I, E35D, M36I, N37D, R41K, W42W*, K55R, R57K, Q61N, L63P, A71V, I72T, T74S, I85V, I93LF
Jones (2012)166236166236JN670122PINAN88SL10LFII15V, Q18QH, K20I, E35D, M36MI, R41K, K45R, R57K, Q61N, L63LP, I85IV, I93LF
 176698176698JN670410PINAM46I, I54V, L76V, V82F L10I, T12I, I13V, I15V, K20I, E35N, M36I, N37D, R41K, R57K, Q61N, L63P, I64VF
 179798179798JN670526PINAM46I, I54V, V82A, L90MG73SL10I, I13V, I15V, K20I, L33L_L, E35N, M36I, R41K, R57K, Q61N, L63P, A71V, I93LF
 191242191242JN670817PINAL90M I15IV, K20I, E35N, M36I, R41K, R57K, D60E, Q61D, I62IV, L63P, A71V, T74S, I93LF
 193037193037JN670877PINAM46I, V82AG73SL10I, G17D, K20I, E35D, M36I, R41K, R57K, Q61N, L63P, I72T, I93LF
 194437194437JN670934PINAM46L, I54V, V82A, L90MK43T, G73SL10I, T12K, I15V, L19Q, K20I, E21ED, L24F, E35D, M36I, N37D, K55R, R57K, D60E, Q61N, L63P, A71V, I72RF
 205464205464JN671362PINAM46I, I54V, V82T, L90MV11I, G73SL10I, K14R, I15V, L19P, K20I, E21D, E35NS, M36I, N37D, R41K, K55R, R57K, Q61N, I62V, L63P, A71V, T74S, I85V, I93LF
Diaz (2015)RenG15609RenG15609KT746637PINAI50L, N88SL33FT12N, I13IV, I15V, L19I, K20I, E35N, M36I, N37D, R41K, R57K, Q61N, L63V, I64V, I72V, T74TA, V77VI, L89MF
 RenG15620RenG15620KT746648PINAM46I, I54V, L76V, V82A, L90M L10I, I13V, I15IV, G16E, K20I, E35N, M36I, N37NS, R41RK, K55R, R57K, Q61N, L63H, A71T, I72V, L89I, T91SF
 RenG16649RenG16649KT747677PINAM46L, I54V, V82A, L90MK43T, T74PL10IV, T12K, I13V, K14KR, I15V, K20I, E35N, M36I, R41K, Q61N, L63T, E65D, I72T, L89MF
 RenG16988RenG16988KT748016PINAM46I, I50L, V82CFLR, L90MF53LL10I, I13L, K20I, E34Q, E35D, M36I, N37T, R41K, K55KN, R57K, Q61N, L63C, I64L, A71V, I72T, T74S, L89M, I93LF
 RenG16531RenG16531KT747559PINAM46L, I54V, I84V, L90MG73SL10I, K20I, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I85V, L89T, Q92KF
 RenG16248RenG16248KT747276PINAM46L, I54V, L76V, V82A, L90ML23IL10I, I13V, I15V, K20I, E35N, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I64L, A71V, I72V, T74S, I93LF
 RenG16813RenG16813KT747841PINAI54V, I84VG73SL10I, K20I, E35N, M36I, R41K, K45R, R57K, Q61N, A71V, I72V, I85V, L89T, Q92QRF
 RenG15985RenG15985KT747013PINAI84C I13V, I15V, G17E, K20I, E35D, M36I, R57K, D60E, Q61N, L63P, L89I, N98IF
 RenG16634RenG16634KT747662PINAI54AV, V82AG73GA, L89VL10I, I13AV, K14KR, K20I, A22AV, E35D, M36I, N37DE, R41RK, R57K, Q61N, L63LP, A71V, I72T, T74S, I93LF
 RenG15696RenG15696KT746724PINAI54V, V82A, L90ML33LFL10I, I13V, K20I, E35D, M36I, R41K, R57K, Q61N, E65D, I72IT, L89MF
 RenG14185RenG14185KT745213PINAG48V, I54V, V82S L10IV, I15V, G16E, K20I, E35D, M36I, N37DE, R41K, R57K, Q61N, I62L, L63N, A71IT, T74S, I85V, Q92KF
 RenG13961RenG13961KT744989PINAL90ML89IMVL10I, K14KNT, I15V, K20I, E35D, M36I, R41K, K45R, K55R, R57K, Q61N, L63P, A71AT, I85IVF
 RenG14280RenG14280KT745308PINAI54V, L90ML23I, F53LL10I, K20I, E35N, M36V, R41K, K55KR, R57K, D60E, Q61N, I62IV, L63D, I64IV, E65ED, I66IF, K70R, A71V, I72T, L89M, Q92QK, I93ILF
 RenG12768RenG12768KT743796PINA  K20I, E35D, M36I, R41K, K43R, R57K, Q61N, T74S, L89I, I93LF
 RenG12683RenG12683KT743711PINAI54V, V82TL24IL10I, T12TK, I13V, K20I, E35D, M36I, R41K, R57K, Q61N, L63A, T74S, L89IF
 RenG12250RenG12250KT743278PINAI54V, V82AV11VI, L33LI, F53LL5LF, W6C, Q7K, T12I, I13V, G16E, K20I, E35D, M36I, R41K, R57K, Q61D, I62V, A71V, I72R, T74A, L89I, T96XF
 RenG12149RenG12149KT743177PINAM46I, I50L, I54V, V82A, L90M L10V, I15V, G16E, K20I, E34A, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, A71V, I72R, T74A, I93LF
 RenG13129RenG13129KT744157PINAM46L, I54V, V82A, L90MN88DL10V, I13K, I15G, K20I, E35N, M36I, L38F, R41K, R57K, Q61H, L63I, A71T, T74S, L89I, Q92KF
 RenG10926RenG10926KT741954PINAM46L, I54V, V82A, L90MV11VI, K43KT, F53FL, G73SL10I, T12N, I15V, L19IMT, K20I, E35N, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, H69Y, A71T, I72T, I85IVF
 RenG11176RenG11176KT742204PINAM46I, I47V, I54V, V82AF53LL10I, T12S, I13V, K20I, M36D, N37I_D, R41K, R57K, Q61N, T74S, L89MF
 RenG10005RenG10005KT741033PINAM46I, I54IL, V82AL24II15V, K20I, E35N, M36I, R41K, K45R, K55KR, R57K, Q61N, L63P, A71AT, I72IT, L89TF