<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype F
Gene PR
Mutation K20I
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 42
Isolates 42
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)105680105680AY365734PINAI54V, V82A, L90MV11I, F53LL10I, I15V, L19I, K20I, E35D, M36I, N37D, R41K, K55R, R57K, D60E, Q61N, L63P, A71VF
 113771113771AY365884PINAI47V, I54M, L90M L10I, I13IV, I15V, K20I, E35DN, M36I, R41K, R57K, Q61N, L63P, T74S, V82VI, I85VF
 114753114753AY365913PINAI54V, V82AL24IL10I, I15V, K20I, E35D, M36I, R41K, R57K, Q61D, A71V, I72RF
Rodrigues (2005)BLF_Pat5BR03SP147AY643162Unknown, IDV>256I54V, V82A L10I, I13V, I15V, G17E, K20I, E35D, M36I, R41K, R57K, Q61N, L63R, E65D, T74S, L89IF
 BLF_Pat12BR03SP110AY643158IDV, NFV271L90M L10I, I15L, L19I, K20I, E35D, M36I, N37S, R41K, R57K, Q61N, L63P, I64V, A71T, I72T, I93LF
Baxter (2006)48-10551055-30707DQ877421PINAM46I, I47V, I54V, V82F, L90MF53FLL10I, K20I, E35D, M36V, R41K, R57K, Q61N, I62IV, L63Q, I64IV, A71V, T74S, I93LF
Waleria-Aleixo (2008)08PR04018508PR040185FJ591216PINAG48V, I54V, V82A, L90MK43TL10V, G17E, K20I, E35D, M36I, N37E, R41K, R57K, Q61D, I62V, A71V, I72R, T74S, L89I, I93LF
 08RJ06048808RJ060488FJ591681PINAM46I, L90M L10I, T12S, K20I, E35D, M36I, R41K, R57K, Q61N, I62V, L63P, T74S, V77IF
Dumans (2009)RENA395RENA395FJ405051IDV, RTV200L76VL89VK20I, E35D, M36I, R41K, R57K, Q61N, I62V, A71V, I93LF
Aulicino (2011)ARM144EJAARM144EJAFJ525825PINAM46L K14KR, I15V, K20I, E35D, M36I, R41K, R57K, Q61DN, L63P, E65D, T74S, L89MF
 2133-L458JCD2133-L458JCDHQ158169PINAI54V, V82A, L90M L10I, T12E, I15V, K20I, E35N, M36I, R41K, R57K, D60E, Q61N, I62V, L63P, A71TF
Jones (2012)148792148792JN669724PINAG48GV, I54V, V82AL24I, F53FL, G73GSL10I, I15V, G16GE, K20I, E35D, M36I, R41K, R57K, Q61D, A71V, I72RF
 173669173669JN670342PINAM46I, I47V, I54V, I84V, L90MV11I, G73SL10I, I15V, G17E, K20I, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, I72R, I85VF
 184144184144JN670673PINAM46I, I50IL, I54AV, V82AL24I, L33F, Q58EL10I, T12N, I13V, G16GE, K20I, E35N, M36I, N37E, R41K, R57K, D60E, Q61N, L63T, I72T, L89MF
 193037193037JN670877PINAM46I, V82AG73SL10I, G17D, K20I, E35D, M36I, R41K, R57K, Q61N, L63P, I72T, I93LF
 193453193453JN670899PINAM46I, I47V, I54V, V82AL10F, K43T, N88DI15V, L19IT, K20I, E35N, M36I, R41RK, R57K, D60E, Q61N, I62IV, L63P, A71V, I85IVF
Diaz (2015)RenG15609RenG15609KT746637PINAI50L, N88SL33FT12N, I13IV, I15V, L19I, K20I, E35N, M36I, N37D, R41K, R57K, Q61N, L63V, I64V, I72V, T74TA, V77VI, L89MF
 RenG15620RenG15620KT746648PINAM46I, I54V, L76V, V82A, L90M L10I, I13V, I15IV, G16E, K20I, E35N, M36I, N37NS, R41RK, K55R, R57K, Q61N, L63H, A71T, I72V, L89I, T91SF
 RenG16649RenG16649KT747677PINAM46L, I54V, V82A, L90MK43T, T74PL10IV, T12K, I13V, K14KR, I15V, K20I, E35N, M36I, R41K, Q61N, L63T, E65D, I72T, L89MF
 RenG16988RenG16988KT748016PINAM46I, I50L, V82CFLR, L90MF53LL10I, I13L, K20I, E34Q, E35D, M36I, N37T, R41K, K55KN, R57K, Q61N, L63C, I64L, A71V, I72T, T74S, L89M, I93LF
 RenG16531RenG16531KT747559PINAM46L, I54V, I84V, L90MG73SL10I, K20I, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I85V, L89T, Q92KF
 RenG16518RenG16518KT747546PINAM46I, I47V, I54V, V82A, L90MV11I, K43T, F53L, G73C, T74P, L89VL10V, T12K, I13A, I15V, L19I, K20I, E34Q, E35D, M36I, N37E, K55R, I62V, L63T, I72VF
 RenG16248RenG16248KT747276PINAM46L, I54V, L76V, V82A, L90ML23IL10I, I13V, I15V, K20I, E35N, M36I, R41K, K55R, R57K, Q61N, I62V, L63P, I64L, A71V, I72V, T74S, I93LF
 RenG16813RenG16813KT747841PINAI54V, I84VG73SL10I, K20I, E35N, M36I, R41K, K45R, R57K, Q61N, A71V, I72V, I85V, L89T, Q92QRF
 RenG15985RenG15985KT747013PINAI84C I13V, I15V, G17E, K20I, E35D, M36I, R57K, D60E, Q61N, L63P, L89I, N98IF
 RenG16634RenG16634KT747662PINAI54AV, V82AG73GA, L89VL10I, I13AV, K14KR, K20I, A22AV, E35D, M36I, N37DE, R41RK, R57K, Q61N, L63LP, A71V, I72T, T74S, I93LF
 RenG16262RenG16262KT747290PINAM46L, I54V, V82AL10F, L24I, K43TI13M, K20I, E35D, M36I, N37E, K55R, R57K, D60E, Q61N, L63P, I72V, L89IF
 RenG15696RenG15696KT746724PINAI54V, V82A, L90ML33LFL10I, I13V, K20I, E35D, M36I, R41K, R57K, Q61N, E65D, I72IT, L89MF
 RenG15167RenG15167KT746195PINAG48M, I54V, V82A, L90MK43T, F53LL10IV, V11L, T12P, I13V, K20I, E35D, M36I, N37K, R41K, R57K, Q61N, L63P, T74S, L89I, Q92KF
 RenG13961RenG13961KT744989PINAL90ML89IMVL10I, K14KNT, I15V, K20I, E35D, M36I, R41K, K45R, K55R, R57K, Q61N, L63P, A71AT, I85IVF
 RenG14280RenG14280KT745308PINAI54V, L90ML23I, F53LL10I, K20I, E35N, M36V, R41K, K55KR, R57K, D60E, Q61N, I62IV, L63D, I64IV, E65ED, I66IF, K70R, A71V, I72T, L89M, Q92QK, I93ILF
 RenG13624RenG13624KT744652PINAM46L, V82VA L10I, T12K, K14I, I15V, K20I, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, E65D, T74S, L89MF
 RenG14313RenG14313KT745341PINAM46L, I54V, V82AL10F, L33F, T74PI13V, K20I, E35D, M36I, R41K, K55R, R57K, Q61N, E65D, L89MF
 RenG12768RenG12768KT743796PINA  K20I, E35D, M36I, R41K, K43R, R57K, Q61N, T74S, L89I, I93LF
 RenG12683RenG12683KT743711PINAI54V, V82TL24IL10I, T12TK, I13V, K20I, E35D, M36I, R41K, R57K, Q61N, L63A, T74S, L89IF
 RenG12250RenG12250KT743278PINAI54V, V82AV11VI, L33LI, F53LL5LF, W6C, Q7K, T12I, I13V, G16E, K20I, E35D, M36I, R41K, R57K, Q61D, I62V, A71V, I72R, T74A, L89I, T96XF
 RenG13129RenG13129KT744157PINAM46L, I54V, V82A, L90MN88DL10V, I13K, I15G, K20I, E35N, M36I, L38F, R41K, R57K, Q61H, L63I, A71T, T74S, L89I, Q92KF
 RenG10926RenG10926KT741954PINAM46L, I54V, V82A, L90MV11VI, K43KT, F53FL, G73SL10I, T12N, I15V, L19IMT, K20I, E35N, M36I, R41K, K55R, R57K, Q61D, I62V, L63P, H69Y, A71T, I72T, I85IVF
 RenG11176RenG11176KT742204PINAM46I, I47V, I54V, V82AF53LL10I, T12S, I13V, K20I, M36D, N37I_D, R41K, R57K, Q61N, T74S, L89MF
 RenG10005RenG10005KT741033PINAM46I, I54IL, V82AL24II15V, K20I, E35N, M36I, R41K, K45R, K55KR, R57K, Q61N, L63P, A71AT, I72IT, L89TF
 RenG10914RenG10914KT741942PINAM46I, I47V, I54V, L76V, V82TL24I, K43TL10IV, T12TP, I13V, I15V, G16E, K20I, M36I, N37E, I62V, L63N, A71V, L89IF
Jenabian (2015)DR26DR26KF735832PINA  I13V, K14R, G17E, K20I, M36I, N37S, R41K, H69K, K70R, L89MF