<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L89V
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 7
Isolates 7
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)TK4015TK4016a NFV31 G73S, L89VT12E, K14R, I15V, L19I, R41KD
 TK4016TK4016a IDV, RTV275 G73S, L89VT12E, K14R, I15V, L19I, R41KD
Baxter (2006)48-30563056-30318DQ877968PINAM46I, I54V, L76V, V82TL10F, L89VI13V, K20M, M36I, R41K, I62V, L63P, A71V, I72V, I93LD
Dau (2010)07867A07867AGU581877PINAV32I, M46I, I47A, L90ML10F, L89VT4A, I13V, K20T, L33V, I62V, L63P, H69Y, A71V, I93LD
 09705A09705AGU581977PINAM46L, I54V, V82AT, I84V, L90ML33F, F53L, L89VL10I, I13V, I15V, K20T, E35D, M36I, N37D, K55R, D60E, I62V, L63P, I66F, K70E, A71V, Q92KD
Jones (2012)187220187220JN670729PINAM46L, I54V, I84V, L90MG48E, L89VL10I, I13V, K20MT, E35D, M36I, R57K, Q61N, I62V, L63P, C67Y, G68E, H69Y, A71V, Q92K, I93LD
 187443187443JN670732PINAG48A, I54V, V82A, I84VL33F, N83ND, L89VL10I, K14R, K20KR, E35D, M36I, R41K, D60E, L63P, A71V, T91S, Q92QR, I93LD

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