<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L89V
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 21
Isolates 21
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Rhee (2005)CA1556CA20616AY796778IDV, NFV, SQV, RTV, APV, LPV228V32VI, I54V, I84V, L90ML10F, V11I, L33LF, G73GS, L89VT12P, I13V, I15V, L19LP, K20T, E35G, M36I, I62V, L63LP, A71X, P79AD
Baxter (2006)12-11341134-30326DQ876024PINAV32I, M46I, I47V, I54M, I84V, L90ML10F, L33F, L89VI13V, I15V, K20T, M36I, N37S, R41K, L63P, A71V, G73D, I93LD
 12-10121012-30717DQ876218PINAV32I, M46I, I47V, I54M, I84V, L90ML10F, L33F, G73S, L89VI13V, I15V, L19I, K20T, E35D, M36I, R41N, F53Y, K55N, D60E, L63P, I64L, I66F, H69K, A71V, V77I, Q92K, T96SD
 48-30563056-30318DQ877968PINAM46I, I54V, L76V, V82TL10F, L89VI13V, K20M, M36I, R41K, I62V, L63P, A71V, I72V, I93LD
 48-30833083-30313DQ877992PINAV32I, M46I, I47V, I54V, V82A, L90MK43T, F53L, G73S, L89VL10V, T12I, I13V, G16A, K20I, M36I, K55R, L63P, A71VD
 48-40244024-30630DQ878258PINAV32I, M46I, I47V, I54L, I84V, L90ML10F, V11I, L33F, L89VK14R, I15V, K20V, E35H, M36IL, R41K, L63P, C67CY, A71I, I85V, Q92KD
 48-41454145-30530DQ878377PINAV32I, M46I, I54M, I84V, L90ML33F, K43T, G73S, L89VL10V, I13V, G16A, K20L, F53Y, D60E, L63P, I66F, A71V, I72L, P79ND
 48-50225022-30606DQ878556PINAM46I, I54V, L76V, I84V, L90ML10F, V11I, Q58E, G73A, L89VI13V, K20I, L33V, E35K, M36I, K55R, D60E, I62V, L63P, I64V, A71V, T91S, I93LD
 48-71347134-30729DQ878972PINAV32I, M46L, V82A, L90MK43T, L89VI13V, K20R, M36I, I62V, L63P, A71VD
 48-90069006-30923DQ877670PINAI54A, V82AL24I, Q58E, L89VL10Y, I13IMV, I15V, K20I, E34KQ, E35D, M36I, N37NS, R41K, R57K, D60E, I62IV, L63P, A71V, I93LD
Jones (2012)187443187443JN670732PINAG48A, I54V, V82A, I84VL33F, N83ND, L89VL10I, K14R, K20KR, E35D, M36I, R41K, D60E, L63P, A71V, T91S, Q92QR, I93LD
Kouri (2012)CU1373-09CU1373-09JQ585294PINAV32I, M46L, L76V, V82AL10F, L33F, L89VI13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92KD
 CU1288-09CU1288-09JQ585288PINAV32I, M46L, L76V, V82AL33LF, L89VL10I, I13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92KD
 CU90-10CU90-10JQ585361PINAI50V, I54L, L90ML10F, L33F, K43T, F53L, L89VQ2P, L5F, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37G, R41K, D60E, L63P, H69HY, A71IV, V77I, V82I, I93ILD
 CU311-10CU311-10JQ585381PINAI50V, I54L, L90ML33F, K43T, F53L, L89VV11L, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37D, R41K, D60E, L63P, H69Y, A71I, V77I, V82ID
Diaz (2015)RenG16766RenG16766KT747794PINAV32I, M46I, I54L, I84V, L90ML10F, V11I, L33F, G73T, L89VI13V, K20M, M36I, I62V, L63P, I66V, A71T, I72V, C95ID
 RenG16895RenG16895KT747923PINAM46I, I47V, I54V, V82A, L90MV11I, F53L, G73S, L89VL10IV, I13V, I15V, L19LAPV, K20I, E35G, M36I, L63P, A71V, I72L, Q92KD
 RenG12426RenG12426KT743454PINAM46I, I54V, V82S, I84VK43T, L89VL10I, I15V, L19IV, K20R, M36I, I62IV, L63P, K70R, A71V, I72M, Q92KD
 RenG13053RenG13053KT744081PINAV32I, M46L, G48GV, I50IL, V82A, L90ML33F, G73GS, L89VL10I, I13V, L19I, L24LF, E34EQ, E35ED, M36I, N37S, R41K, K55HQ, I62IV, L63A, I64L, A71VD
 RenG12091RenG12091KT743119PINAM46I, I54V, V82A, L90MG73S, L89VL10V, I13V, K20T, L33L_L, M36I, R41K, K55R, I62IV, L63P, I64IL, A71V, I93L, N98ID
 RenG10617RenG10617KT741645PINAV32I, M46I, I47V, I54V, V82A, L90MV11I, L33F, G73S, L89VL10V, I13V, I15V, L19P, K20R, M36I, N37D, K55R, R57K, I62V, L63P, I64L, A71V, I72VD