<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L89I
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 11
Isolates 11
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)101028101028AY365623PINAI54V, L76V, V82A L10I, I13V, I15V, K20M, E35D, M36I, R41K, Q61N, L63P, A71V, I72T, L89I, I93LD
Baxter (2006)48-14321432-30818DQ877822PINAM46I, I54V, L76V, V82TL24IL10I, I13A, K20I, E35D, M36I, R41K, Q61H, L63P, H69K, T74S, L89ID
Dau (2010)13578A13578AGU582074PINAV32I, M46I, I54V, L76V, I84V, L90ML10F, L33F, K43TI13V, K20R, E35D, M36I, R41RK, K55KR, D60E, L63P, I64V, L89ID
Aulicino (2011)ARM522BCEARM522BCEFJ525832PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, K20R, E35N, M36I, K55R, R57K, Q61N, I62V, L63P, L89ID
Diaz (2015)RenG15889RenG15889KT746917PINAM46I, I54V, L76V, V82AL10F, L24I, L33FI13V, K20R, M36I, N37D, R41K, K55R, R57K, Q61N, L63P, I72V, L89ID
 RenG15645RenG15645KT746673PINAM46I, I54V, I84V, L90ML10F, F53L, T74PI13V, K20R, E35D, M36I, R41K, K55H, R57K, L63P, H69R, A71V, L89I, T91S, Q92KD
 RenG15716RenG15716KT746744PINAI50V, I54V, V82AL33FL10V, I13V, G16A, L19I, K20R, M36I, N37D, L63P, A71T, I72V, L89I, L97F, N98KD
 RenG17271RenG17271KT748299PINAM46L, G48Q, I54V, L76V, V82AL33I, F53LL10V, I13V, K14KR, L19V, K20M, M36I, D60E, Q61N, I62IV, L63P, T74S, L89I, T91SD
 RenG17344RenG17344KT748372PINAM46I, I54V, L76V, V82A, L90ML33FL10V, T12I, I13V, G16E, K20R, E35D, M36I, N37T, R41K, R57K, D60E, Q61D, I62V, I72R, L89ID
 RenG12217RenG12217KT743245PINAM46I, I54V, V82F, L90M L10I, I15V, K20T, E35N, M36I, R41KT, K43Q, R57K, D60N, Q61D, I62V, L63P, I64L, V77I, L89I, I93LD
 RenG12729RenG12729KT743757PINAG48M, I54V, V82VA, L90ML33I, F53L, N83DL10V, T12I, I13A, A22V, E35H, M36I, N37NS, R41K, K43KQ, R57K, Q61N, I62V, L63P, H69Y, A71V, I72T, L89I, I93LD