<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation N88D
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 34
Isolates 34
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG8181_w56 NFV55D30NN88DI13V, R41K, L63P, A71T, V77ID
Vergne (2003)VL01SN160HALD01SN160AJ583742IDV  N88DQ7L, T12S, I15V, E35D, M36I, R41K, Q61N, I62V, L63P, A71TD
Gomez-Carrillo (2004)103136103136AY365669PINAD30N, V82AN83D, N88DL10I, I13V, A22V, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, A71VD
Montes (2004)MB_patDER02_DER736AJ577878NFV179D30NN88DL10Y, I13V, E35D, M36I, I62V, L63P, I64V, T74S, V77ID
Non-B Workgroup (2005)UK1557UK1557AY900679NFV, SQV104D30NN88DL10V, I13V, E35D, M36I, R41K, L63PD
 TK3011TK3011 SQV, NFV231D30NN88DI13V, I15V, K20T, E35D, M36I, N37NY, R41K, I64V, T74SD
Baxter (2006)12-30773077-30403DQ877151PINAD30NL10F, N88DI13V, K14R, E35D, M36I, R41K, I62IV, L63Q, I64VD
Aulicino (2011)ARL411LCOARL411LCOFJ525808PINAD30NN88DL10Y, I13V, I15V, K20T, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63H, I72V, V75ID
 ARM856HJMARM856HJMFJ525843PINAD30N, M46L, I54V, L90MN88DL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, I62V, L63P, A71T, I72V, I93LD
 444-O288CCR444-O288CCRHQ158164PINAD30NN88DL10I, I13V, I15V, K20T, E35N, M36I, R41K, Q61N, L63P, I72T, T74M, V77I, I93LD
Jones (2012)129393129393JN669468PINAV82A, L90MN88DL10I, I13A, A22V, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, A71VD
 171752171752JN670267PINAD30NN88DL10V, I13V, I15IV, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, V75I, I93LD
 172708172708JN670297PINAD30NN88DI13V, I15V, E35D, M36I, R41K, R57K, Q61N, L63P, A71T, I72TD
 177590177590JN670450PINAD30NN88DL10V, I13V, I15V, K20R, E35D, M36I, R41K, Q61D, L63P, V75I, I93LD
 188898188898JN670762PINAD30NN88DL10V, I13V, K14R, G16E, K20M, E35G, M36I, R41K, R57K, Q61N, L63SD
 195199195199JN670968PINAD30NL33F, N88DL10M, I13V, I15IV, E35D, M36L, R41K, R57K, Q61N, L63A, I93LD
 204389204389JN671339PINAD30N, M46IN88DL10I, I15V, G17E, K20T, M36I, N37K, R41K, R57K, Q61D, L63P, I72R, I93LD
Kouri (2012)CU845-09CU845-09JQ585267PINA L33F, I50IS, N88DM36I, R41K, D60E, I62V, L63P, H69Q, A71TD
 CU691-09CU691-09JQ585261PINAD30N, V32I, M46I, I47V, I54L, V82AL10LF, L33F, F53FL, Q58E, N88DI13V, I15V, L19I, K20R, E35D, M36L, N37T, R41T, K45R, D60E, L63P, H69Q, K70R, I72V, V77I, L89FD
Diaz (2015)RenG17196RenG17196KT748224PINAD30N, L90LML10F, Q58E, N88DI13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63HQ, I64VD
 RenG15602RenG15602KT746630PINAD30N, M46I, V82AL33I, F53L, N88DL10V, I13IV, G17GDE, K20R, E35D, M36I, N37D, D60E, I62V, L63P, I64IV, A71T, I72IT, V75VID
 RenG16451RenG16451KT747479PINAD30NL10F, L33I, N88DQ7E, K20T, E35DN, M36I, R41K, R57K, D60E, Q61E, L63P, I72VD
 RenG17289RenG17289KT748317PINAD30N, M46I, I54IV, V82A, L90ML10F, L33F, F53FL, N88DI13V, R41K, I62V, L63P, H69Y, A71T, I72T, V77ID
 RenG16117RenG16117KT747145PINAD30NN88DL10I, T12I, I13V, I15V, E35D, M36I, N37D, R41K, I62V, L63P, K70KR, A71T, I72T, V75ID
 RenG14787RenG14787KT745815PINAM46I, I47IV, I54V, V82AL10F, L33F, N88DI13V, I15V, E35D, M36I, N37ND, R57K, Q61N, L63P, I64LD
 RenG14682RenG14682KT745710PINAM46I, I54V, V82AN88DL10V, I13V, I15V, G16E, K20I, E35N, M36I, R41K, K45R, K55KR, R57K, Q61N, L63Q, I64V, T74SD
 RenG13532RenG13532KT744560PINAD30N, M46L, I54IV, V82A, L90ML33F, F53L, N88DL10V, T12Q, I13V, I15V, G16GE, K20R, E35D, M36I, R41K, K55KN, Q61N, L63S, I93ILD
 RenG13073RenG13073KT744101PINAD30N, I50L, V82AL33F, N88DL10I, I13V, K20R, E35D, M36I, N37E, K45I, I62IV, L63T, I64V, A71AITV, T74S, I93LD
 RenG13474RenG13474KT744502PINAD30NN88DL10I, I13V, K14KR, E35D, M36I, R57K, Q61N, L63P, I72IT, L89LMD
 RenG13314RenG13314KT744342PINAV82A, L90MN88DL10I, I13IV, G16A, K20R, E35D, M36I, N37ND, R41K, K43KR, R57K, Q61N, L63P, I64IV, K70KN, A71V, I72V, I93IMD
 RenG11212RenG11212KT742240PINAD30N, I54LL10F, L33I, N83D, N88DI13V, K14R, A22V, E34N, M36I, N37D, L63P, H69K, A71V, I72V, T74SD
 RenG11672RenG11672KT742700PINAD30N, M46L, I54V, V82ACGS, L90ML33LF, F53L, N88DI15V, K20T, E35N, M36I, N37NT, R41K, Q61H, I62V, L63P, I64L, A71F, V77IL, I93LD
 RenG11284RenG11284KT742312PINAD30N, M46L, I54V, V82ACGS, L90ML33LF, F53L, N88DI15V, K20T, E35N, M36I, N37NT, R41K, Q61H, I62V, L63P, I64L, A71F, V77IL, I93LD
 RenG10136RenG10136KT741164PINAD30N, I50V, I54V, V82A, L90LML33F, N88DL10V, I13V, K20R, E35D, M36I, N37E, R41Y, K45Q, R57K, Q61N, L63ST, E65D, A71L, L89LM, I93LD