<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation I84V
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 31
Isolates 32
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Monno (2003)ML_Pat89ML_Pat89 PINAI54IV, I84V, L90MG73TL10I, I15V, G16E, L19Q, K20M, I62V, L63N, A71V, I72T, P79D, I93LD
Gomez-Carrillo (2004)9827298272AY365573PINAI54V, I84V, L90ML33F, T74PL10I, L19V, I62V, L63P, H69Q, A71V, T91SD
Machado (2004)cs232cs232AY502101Unknown, NFVNAI84V, L90MG73SL10I, E35D, M36I, R41K, L63P, A71VD
Montes (2004)MB_patESTU01_ESTU702AJ577887SQV, RTV, NFV, IDV309M46I, I84V, L90MV11I, G73SL10V, I13V, K20I, L33V, I62V, L63PD
Non-B Workgroup (2005)TK2001TK2001 SQV, RTV, NFV94M46I, I84VN83DL10I, I13V, A22V, E35G, M36I, I62V, L63P, I64V, A71V, I93LD
 TK3008TK3008 SQV, NFV344I84VN83DL10I, I13V, A22V, M36I, R41K, I62V, L63P, I64V, H69HYD
Rhee (2005)CA1556CA20616AY796778IDV, NFV, SQV, RTV, APV, LPV228V32VI, I54V, I84V, L90ML10F, V11I, L33LF, G73GS, L89VT12P, I13V, I15V, L19LP, K20T, E35G, M36I, I62V, L63LP, A71X, P79AD
 ASRU017ASRU017 SQV, IDV, RTV91I84V, L90M L10I, T12S, I15V, K20T, E35G, M36I, R41K, I64V, A71T, I85V, I93LD
Baxter (2006)12-11341134-30326DQ876024PINAV32I, M46I, I47V, I54M, I84V, L90ML10F, L33F, L89VI13V, I15V, K20T, M36I, N37S, R41K, L63P, A71V, G73D, I93LD
 12-10121012-30717DQ876218PINAV32I, M46I, I47V, I54M, I84V, L90ML10F, L33F, G73S, L89VI13V, I15V, L19I, K20T, E35D, M36I, R41N, F53Y, K55N, D60E, L63P, I64L, I66F, H69K, A71V, V77I, Q92K, T96SD
 12-30313031-30303DQ877211PINAM46MI, I54V, I84V, L90ML10F, V11I, G73ST4TP, I13V, I15V, K20I, E35NS, M36I, R41K, D60DE, I62V, L63P, A71T, I72LD
  3031-30825DQ876734PI, RTV, TPV>25M46I, I54V, I84V, L90ML10F, V11I, G73SI13V, I15V, K20I, E35NS, M36I, R41K, D60DE, I62V, L63P, A71T, I72LD
 48-12251225-30417DQ877757PINAI84V, L90LM Q7E, L10I, G16GE, P39S, R41K, D60E, L63P, I64V, V77I, I85IVD
 48-40244024-30630DQ878258PINAV32I, M46I, I47V, I54L, I84V, L90ML10F, V11I, L33F, L89VK14R, I15V, K20V, E35H, M36IL, R41K, L63P, C67CY, A71I, I85V, Q92KD
 48-41454145-30530DQ878377PINAV32I, M46I, I54M, I84V, L90ML33F, K43T, G73S, L89VL10V, I13V, G16A, K20L, F53Y, D60E, L63P, I66F, A71V, I72L, P79ND
 48-50225022-30606DQ878556PINAM46I, I54V, L76V, I84V, L90ML10F, V11I, Q58E, G73A, L89VI13V, K20I, L33V, E35K, M36I, K55R, D60E, I62V, L63P, I64V, A71V, T91S, I93LD
 48-61576157-30704DQ878733PINAG48A, I54V, V82A, I84V, L90ML33F, Q58E, G73GS, L89LVT4S, L10I, K20R, E35D, M36L, R57RK, I62V, L63P, A71V, I72ILM, Q92KD
 48-71027102-40225DQ878956PI, RTV, TPV>30M46I, I47A, I84V L10V, I13V, K20T, L33V, M36I, N37C, R57K, L63P, I64VD
Waleria-Aleixo (2008)08RJ06060708RJ060607FJ591767PINAM46I, I54V, I84V, L90ML10F, L33F, T74PK20I, E35N, M36I, N37DE, I62V, L63P, I64M, C67F, H69K, A71V, I72V, T91TS, Q92KD
Jones (2012)133389133389JN669521PINAI54L, I84VL33FL10I, K14R, E35D, M36I, R41K, D60E, L63P, A71V, I93LD
 163239163239JN670057PINAM46I, V82T, I84VL10FT12K, I13V, G16E, L19P, K20R, M36I, L63T, I64V, E65D, I72T, T74SD
 187443187443JN670732PINAG48A, I54V, V82A, I84VL33F, N83ND, L89VL10I, K14R, K20KR, E35D, M36I, R41K, D60E, L63P, A71V, T91S, Q92QR, I93LD
 200084200084JN671190PINAM46I, I54IV, I84V, L90ML33F, K43KT, T74PL10I, I13V, K20KR, M36I, R41RK, K55KR, I62V, L63P, H69K, K70KT, A71V, T91SD
Kouri (2012)CU749-09CU749-09JQ585263PINAM46L, I84VN83DL10I, I15V, G16E, K20R, M36I, R41K, D60E, I62IV, L63T, V82I, L89LFD
 CU1627-09CU1627-09JQ585302PINAI54V, V82A, I84V, L90M L10I, K20I, E35G, M36I, R41K, D60E, I62V, L63P, H69HQ, A71VD
 CU1316-09CU1316-09JQ585291PINAI84V, L90M E35D, M36I, R41K, L63P, H69K, L89M, I93LD
Diaz (2015)RenG15645RenG15645KT746673PINAM46I, I54V, I84V, L90ML10F, F53L, T74PI13V, K20R, E35D, M36I, R41K, K55H, R57K, L63P, H69R, A71V, L89I, T91S, Q92KD
 RenG15641RenG15641KT746669PINAM46I, I54L, L76V, I84VL10F, V11VII13V, I15V, L19LQ, K20I, E35NS, M36I, R41K, K55KR, R57RK, D60E, Q61N, I62V, L63P, I64IV, A71V, I72V, N83NH, T91SD
 RenG16766RenG16766KT747794PINAV32I, M46I, I54L, I84V, L90ML10F, V11I, L33F, G73T, L89VI13V, K20M, M36I, I62V, L63P, I66V, A71T, I72V, C95ID
 RenG16023RenG16023KT747051PINAV32I, M46L, I47V, I50L, V82A, I84VL33F, Q58ET12N, I13V, I15V, K20R, E35D, M36I, N37E, Q61QH, L63T, I64V, A71V, I72V, G78GV, R87RI, L89MD
 RenG12426RenG12426KT743454PINAM46I, I54V, V82S, I84VK43T, L89VL10I, I15V, L19IV, K20R, M36I, I62IV, L63P, K70R, A71V, I72M, Q92KD
 RenG13261RenG13261KT744289PINAM46I, I54V, I84V, L90MV11I, G73CL10I, I13AV, K14KI, I15IV, Q18H, K20I, E35D, M36I, N37ND, I62V, L63P, I64V, C67Y, I72L, T74S, T91TCSD