<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation I84V
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 35
Isolates 35
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Rousseau (2000)MNR18MNRMP1263AJ405965SQV, NFV69I84V, L90MG73SL10I, L19T, K20R, E35D, M36I, N37D, I62V, L63P, H69Y, A71T, I72TD
Monno (2003)ML_Pat89ML_Pat89 PINAI54IV, I84V, L90MG73TL10I, I15V, G16E, L19Q, K20M, I62V, L63N, A71V, I72T, P79D, I93LD
Montes (2004)MB_patESTU01_ESTU702AJ577887SQV, RTV, NFV, IDV309M46I, I84V, L90MV11I, G73SL10V, I13V, K20I, L33V, I62V, L63PD
Non-B Workgroup (2005)TK2001TK2001 SQV, RTV, NFV94M46I, I84VN83DL10I, I13V, A22V, E35G, M36I, I62V, L63P, I64V, A71V, I93LD
 TK3008TK3008 SQV, NFV344I84VN83DL10I, I13V, A22V, M36I, R41K, I62V, L63P, I64V, H69HYD
Rhee (2005)ASRU017ASRU017 SQV, IDV, RTV91I84V, L90M L10I, T12S, I15V, K20T, E35G, M36I, R41K, I64V, A71T, I85V, I93LD
Baxter (2006)48-12251225-30417DQ877757PINAI84V, L90LM Q7E, L10I, G16GE, P39S, R41K, D60E, L63P, I64V, V77I, I85IVD
Dau (2010)09705A09705AGU581977PINAM46L, I54V, V82AT, I84V, L90ML33F, F53L, L89VL10I, I13V, I15V, K20T, E35D, M36I, N37D, K55R, D60E, I62V, L63P, I66F, K70E, A71V, Q92KD
 13578A13578AGU582074PINAV32I, M46I, I54V, L76V, I84V, L90ML10F, L33F, K43TI13V, K20R, E35D, M36I, R41RK, K55KR, D60E, L63P, I64V, L89ID
Aulicino (2011)ARN397RLRARN397RLRFJ525859PINAM46L, I54L, V82T, I84VL24I, L33F, K43TE35D, M36I, N37E, R41K, R57K, D60N, Q61N, L63T, I64L, A71I, I72T, L89M, I93LD
Jones (2012)133389133389JN669521PINAI54L, I84VL33FL10I, K14R, E35D, M36I, R41K, D60E, L63P, A71V, I93LD
 163239163239JN670057PINAM46I, V82T, I84VL10FT12K, I13V, G16E, L19P, K20R, M36I, L63T, I64V, E65D, I72T, T74SD
 187220187220JN670729PINAM46L, I54V, I84V, L90MG48E, L89VL10I, I13V, K20MT, E35D, M36I, R57K, Q61N, I62V, L63P, C67Y, G68E, H69Y, A71V, Q92K, I93LD
 187443187443JN670732PINAG48A, I54V, V82A, I84VL33F, N83ND, L89VL10I, K14R, K20KR, E35D, M36I, R41K, D60E, L63P, A71V, T91S, Q92QR, I93LD
 200084200084JN671190PINAM46I, I54IV, I84V, L90ML33F, K43KT, T74PL10I, I13V, K20KR, M36I, R41RK, K55KR, I62V, L63P, H69K, K70KT, A71V, T91SD
 201210201210JN671216PINAI54V, V82T, I84VL33F, F53LL10I, I15V, K20R, E35D, M36I, N37D, R41K, Q61N, L63S, I64L, A71V, I72T, T74S, I85V, L89M, I93LD
 201919201919JN671244PINAI84V, L90MF53LL10I, T12I, I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, A71I, I72TD
Kouri (2012)CU749-09CU749-09JQ585263PINAM46L, I84VN83DL10I, I15V, G16E, K20R, M36I, R41K, D60E, I62IV, L63T, V82I, L89LFD
 CU263-10CU263-10JQ585374PINAV32I, I54M, I84VV11I, L33F, F53FLQ2L, L5LF, L10V, I13V, K14E, I15V, G17D, K20R, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, L63P, I64V, A71V, T74E, V82ID
 CU1627-09CU1627-09JQ585302PINAI54V, V82A, I84V, L90M L10I, K20I, E35G, M36I, R41K, D60E, I62V, L63P, H69HQ, A71VD
Diaz (2015)RenG15645RenG15645KT746673PINAM46I, I54V, I84V, L90ML10F, F53L, T74PI13V, K20R, E35D, M36I, R41K, K55H, R57K, L63P, H69R, A71V, L89I, T91S, Q92KD
 RenG15734RenG15734KT746762PINAM46I, I54V, V82F, I84V L10V, I15V, K20T, E35N, M36I, R41K, I62V, L63P, I64IV, T74AD
 RenG15641RenG15641KT746669PINAM46I, I54L, L76V, I84VL10F, V11VII13V, I15V, L19LQ, K20I, E35NS, M36I, R41K, K55KR, R57RK, D60E, Q61N, I62V, L63P, I64IV, A71V, I72V, N83NH, T91SD
 RenG16766RenG16766KT747794PINAV32I, M46I, I54L, I84V, L90ML10F, V11I, L33F, G73T, L89VI13V, K20M, M36I, I62V, L63P, I66V, A71T, I72V, C95ID
 RenG16023RenG16023KT747051PINAV32I, M46L, I47V, I50L, V82A, I84VL33F, Q58ET12N, I13V, I15V, K20R, E35D, M36I, N37E, Q61QH, L63T, I64V, A71V, I72V, G78GV, R87RI, L89MD
 RenG17355RenG17355KT748383PINAM46I, I84V, L90ML10F, G73CSTK20R, E35D, M36I, N37ND, R41K, I62V, L63P, H69K, A71AV, T74S, V77I, I85V, I93LD
 RenG16182RenG16182KT747210PINAM46I, I54V, I84V, L90MV11I, G73SL10I, I13IV, I15V, K20KIM, E21Q, E35D, M36I, N37D, R57RK, D60DE, Q61N, L63P, H69HR, A71V, I72M, I85IV, I93LD
 RenG14385RenG14385KT745413PINAM46L, G48Q, I54V, L76V, I84VL24IL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57RK, Q61N, L63T, I64L, I72T, V82VI, L89M, Q92QKD
 RenG14898RenG14898KT745926PINAM46I, I54V, I84V, L90MV11I, G73SL10IM, T12P, K14*, I15V, L19P, K20I, E35D, M36I, N37D, D60DE, Q61N, L63P, H69HR, A71V, I72M, I85V, I93LD
 RenG12432RenG12432KT743460PINAM46L, I54V, I84VL24I, G48EL10I, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, I64L, I72T, V82VI, L89M, Q92KD
 RenG12426RenG12426KT743454PINAM46I, I54V, V82S, I84VK43T, L89VL10I, I15V, L19IV, K20R, M36I, I62IV, L63P, K70R, A71V, I72M, Q92KD
 RenG12984RenG12984KT744012PINAM46I, I54V, V82A, I84V, L90ML33F, K43T, G73TL10V, L19V, K20R, E35D, M36I, R41N, D60E, Q61D, I62V, L63P, H69Y, A71T, I72TD
 RenG12872RenG12872KT743900PINAM46L, I54V, I84V, L90ML10F, V11VI, Q58E, G73SI15V, K20KM, M36I, N37E, R41K, K55R, R57RK, I62V, L63P, A71V, N83SD
 RenG10088RenG10088KT741116PINAM46I, I54V, I84V, L90MQ58EL10I, I13A, K14IM, L19Q, K20R, A22V, E35D, M36I, K55R, R57K, I62V, L63P, I64V, I66V, V82I, Q92K, I93L, C95FD
 RenG11215RenG11215KT742243PINAM46L, I54V, V82F, I84V, L90ML33F, Q58EL10IV, I15V, K20KR, E35N, M36IV, N37E, R41K, R57RK, I62V, I64V, A71V, I93LD