<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation V82I
Rx PI-naive
IncludeMixtures No
References 28
Patients 38
Isolates 38
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Holguin (2000)AHHC18HolgHC19AF188350None   I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, I64M, C67E, H69K, V82I, I85M, L89MD
Eshleman (2001)SE851SE851AF388165None   I13V, K14KR, I15IV, R41K, I64V, V82ID
Cuevas (2002)CU57CU57AF425438None   I13V, L19I, K20I, E35D, M36I, R41K, H69K, V82I, L89MD
Eshleman (2004)ESH_Pat71ESH61AY435237None   I13V, R41K, H69HY, K70KR, V82ID
Niama (2006)ARV32ARV32FM164886None  L33IT12N, L19I, M36I, R41K, Q61H, H69Q, V82I, L89FD
Church (2007)061-111500X061EF612008None   I13V, R41K, H69HY, K70KR, V82ID
 851-146773u851EF612169None   T12TA, I13V, K14KR, R41K, I64V, H69HY, V82ID
Church (2008)368341X368341XEU380736None   I13V, K14R, I15V, R41K, L63Q, I64V, V82ID
Nyombi (2008)TBK080TBK080EU251767None   I13V, K14KR, I15V, G16E, K20M, P39S, G40K, I62IV, L63LF, I64V, V82ID
 TBK093TBK093EU251775None   T12S, I13V, I15V, L19I, E35D, R41K, L63T, H69KQ, A71T, V82I, I93LD
Florea (2011)3160_20073160_2007JQ083051None   T12TKPQ, I15IV, G16GE, L19LI, E35D, M36I, R41K, K45KR, R57K, I62V, L63T, E65D, I72IT, V82I, L89MD
Hamers (2011)CP076302943CP076302943HQ995042None   N37NS, R41K, I64V, V82ID
 CP076302958CP076302958HQ995046None   R41K, I64V, V82ID
Kasang (2011)2873328733HM572334None   I13V, R41K, L63T, I64L, V82ID
 1719517195HM572359None   I13V, R41K, L63T, I64L, V82ID
Chen (2012)YN10DH0062YN10DH0062JQ658685None   T12TA, K14R, L19I, M36L, R41K, R57K, I62IV, L63P, V82I, I93LD
Delwart (2012)480-0722-4480-0722-4JN214951None   I15V, G16E, K20R, M36I, N37K, R41K, Q61E, I62V, L63T, E65D, I72T, V82ID
Karlsson (2012)SE_82SE_82JQ698720None  Q58EI13V, R41K, D60E, I62V, L63T, I64V, E65D, V77I, V82ID
Machado (2012)CUPL1007CUPL1007HQ655384None   M36I, R41K, K43R, I62V, L63P, H69Q, K70R, I72M, V82I, I93LD
 CUPL1048CUPL1048JN000020None   I15V, E35D, M36I, R41K, K43R, L63P, H69Q, V82ID
Nazziwa (2012)63214306321430JX499013None   I13V, M36I, R41K, I64V, K70R, V82ID
Bila (2013)MzJun186HIV-1KF927382None   I3N, I13V, R41K, D60E, L63A, I64V, H69Q, V77I, V82ID
Hassan (2013)RS11000315RS11000315JQ698394None   I15V, E35D, R41K, L63P, I72IV, V82ID
Heipertz (2013)306347_RT306347_RTJX863949None   I15V, G16E, M36I, N37K, R41K, Q61E, I62V, L63T, E65D, I72T, V82ID
Kiptoo (2013)KAP049KAP049KC516898None   E35D, R41K, D60EG, I64V, V77I, V82I, T96TPD
Nzeyimana (2013)102_1137102_1137HG780835None   I13V, L33V, R41K, I64V, V75I, V82ID
Sigaloff (2013)JCR101_0JCR101_0JX182000None   I3N, I13V, K14R, I15V, R41K, L63Q, I64V, V82ID
Temereanca (2013)SR60SR60JX966527None   L10V, I13V, I15V, G16E, K20R, M36I, R41K, R57K, L63T, E65D, T74S, V82I, L89MD
Lee (2014)AMU064AMU064KJ906682None   I13V, M36I, R41K, I64V, V82ID
 MBA1292MBA1292KJ906983None   I13IV, L19I, M36I, R41K, R57RK, I64V, V82ID
 MBA1059MBA1059KJ906760None   I13V, L33LV, E35ED, N37ST, P39PS, R41K, L63PQ, I64V, I72V, V82ID
 MBA1311MBA1311KJ907000None   I13V, K20R, M36I, R41K, D60E, Q61E, I62V, L63A, I64V, V82ID
 MBA1381MBA1381KJ907067None   I13V, M36I, R41K, L63C, I64V, V82ID
Niculescu (2014)DU3890DU3890KJ194732None   L10V, T12TS, I13IV, L19Q, L33V, M36I, R41K, L63S, I64V, E65D, V82ID
Mulu (2015)ETH-G-5768ETH-G-5768KF026185None   G16E, M36I, R41K, I62V, L63S, E65D, I72T, V82ID
Hoenigl (2016)M1104666M1104666KU574293None   I13V, R41K, L63S, I64V, H69Y, V82ID
 M1116295M1116295KU574311None   I13V, R41K, L63S, H69Y, V77I, V82ID
Zeh (2016)0515680_040515680_04KU248503None   M36I, N37K, R41N, I62V, L63A, H69K, V82I, L89M, I93LD