<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation V82A
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 45
Isolates 45
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M39M39AY010402NFV M46I, I54V, V82A G16E, K20M, M36I, P39Q, R41K, L63R, I64VD
Gomez-Carrillo (2004)101028101028AY365623PINAI54V, L76V, V82A L10I, I13V, I15V, K20M, E35D, M36I, R41K, Q61N, L63P, A71V, I72T, L89I, I93LD
 103136103136AY365669PINAD30N, V82AN83D, N88DL10I, I13V, A22V, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, A71VD
 113381113381AY365875PINAI54L, V82A, L90ML33F, K43T, F53LT12M, I13V, I15V, Q18H, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71I, I72LD
Non-B Workgroup (2005)TK1009TK1009a IDV, NFV, RTV, LPV239M46I, I54V, V82AL24IL10I, M36I, N37D, R41K, L63P, I64V, A71AV, I72VD
 TK2014TK2014 SQV, RTV, IDV, NFV307M46L, I54V, V82A L10V, R41K, D60E, L63P, I66IF, A71V, T74S, V77ID
 TK3023TK3023 RTV221I54V, V82AL33FI13V, L19T, K20R, E35ED, M36I, R41K, L63V, I64VD
 TK3037TK3037 RTV196I54V, V82A L10V, T12TA, I13V, K14R, G16A, R41K, K43R, I62V, L63P, A71TD
Baxter (2006)12-22582258-30721DQ876701PINAI54V, V82AL10FI13V, G16E, K20I, E35D, M36I, P39S, R41K, K45A, R57KT, I62V, L63C, I64VD
 48-12121212-30812DQ877754PINAM46L, I54V, V82AL24I, L33FL10V, I15V, E35D, M36I, N37ND, R41K, I62V, L63PD
 48-14391439-30929DQ877829PINAM46I, I54V, L76LV, V82A, L90ML10FII13V, K20I, E34EK, M36I, R41K, I62V, L63P, I64IV, A71T, L89LI, I93LD
 48-22442244-30722DQ877883PINAV32I, M46I, I54V, V82A, L90MK43T, G73TL10V, I15V, K20R, M36I, R41N, K55R, D60E, L63P, H69HR, K70R, A71V, I93L, C95VD
 48-33733373-30620DQ878231PINAM46L, G48V, I54V, V82A L10V, I15V, L19I, R41K, I62V, L63S, I64L, V77ID
 48-50145014-30514DQ878549PINAM46I, I54V, V82A, L90LML10F, Q58EI13V, K20I, E35D, M36I, R41K, D60E, I62V, L63P, I64V, N83SD
 48-50525052-30515DQ878573PINAM46MI, G48M, I54V, V82A, L90MF53L, L89IVT4S, L10IV, I13V, K14R, G17DE, K20I, L33L_L, M36V, R41K, L63P, H69K, K70R, A71T, T74S, Q92KD
Cardoso (2009)3117BRGO3117FJ638454PINAM46I, I54V, L76V, V82A, L90ML33FL10V, I13V, I15V, K20R, E35D, M36I, K55R, R57K, D60E, I62V, L63P, A71V, I72V, I93LD
Koyalta (2009)8TCHAD-8FJ688175IDV26V82A L10I, T12S, I15V, L19I, E35D, M36I, R41K, L63P, K70E, A71T, I93LD
Dau (2010)07059A07059AGU581816PINAM46MI, I54V, V82A, L90LM L10I, I13V, I15V, K20V, M36I, R41K, I62V, L63Q, I64V, E65D, I72V, T74SD
Aulicino (2011)ARL636VSQARL636VSQFJ525813PINAM46I, I47V, I54V, V82AL24I, L33F, K43T, F53L, Q58EL10V, G16A, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71V, I93LD
 ARM522BCEARM522BCEFJ525832PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, K20R, E35N, M36I, K55R, R57K, Q61N, I62V, L63P, L89ID
 ARN394FGLARN394FGLFJ525858PINAI54V, V82A, L90M L10V, K20R, E35D, M36I, N37D, R41K, R57K, Q61D, I62V, L63V, A71V, I72V, T74SD
El Annaz (2012)1365013650.PRJN185268IDV52M46L, I54A, V82A L10I, K20R, E35D, M36I, N37D, R57K, L63P, I64V, K70T, A71V, I93LD
Jones (2012)127508127508JN669438PINAI54V, V82A, L90ML33I, F53L, G73SL10I, I13V, K20R, E35D, M36I, R41K, K43KE, K55R, R57K, D60EK, Q61N, I62IV, L63P, A71IV, I72V, G94GD, C95LD
 129393129393JN669468PINAV82A, L90MN88DL10I, I13A, A22V, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, A71VD
 159279159279JN669946PINAI47V, I54V, V82A, L90ML33F, G48W, F53L, Q58EL10V, I13V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, C67E, A71V, I93LD
 159575159575JN669956PINAI54V, V82A L10V, I15V, G16GE, K20M, E35D, M36I, R41K, K45R, R57K, L63PS, A71TD
 166915166915JN670139PINAM46I, I54V, V82A L10I, I13A, K20R, A22V, E35ED, M36I, N37D, K55R, R57K, Q61DN, I62IV, L63P, A71T, I72T, T74S, N83S, Q92QK, I93LD
 170719170719JN670232PINAI54V, V82A, L90ML33IL10I, I13V, K14R, K20M, E35D, M36I, N37D, R41K, Q61N, L63P, A71T, I72TD
 171784171784JN670271PINAI54IV, V82A, L90ML33LFL10V, I13V, K20KR, E35D, M36I, R41K, R57K, Q61D, I62V, L63PT, A71V, I72T, T74S, I93LD
 172862172862JN670305PINAM46L, I54V, V82A, L90ML33FL10V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63P, I64L, A71V, Q92K, I93LD
 175531175531JN670363PINAM46L, I54IV, V82AL24I, L33LFL10V, I15V, K20M, E35DN, M36I, N37D, R41K, K55KR, R57K, Q61D, A71V, I72TD
 178114178114JN670471PINAI54V, V82A, L90M L10V, K20R, M36I, R41K, R57K, Q61N, L63A, A71V, T74S, I93LD
 187443187443JN670732PINAG48A, I54V, V82A, I84VL33F, N83ND, L89VL10I, K14R, K20KR, E35D, M36I, R41K, D60E, L63P, A71V, T91S, Q92QR, I93LD
 187807187807JN670741PINAM46L, I54V, V82A, L90ML33F, K43T, G73SQ7QH, L10V, I13V, K20R, E35D, M36I, L38LS, R41K, I62V, L63P, H69R, A71T, I72T, V77ID
 193836193836JN670912PINAM46I, I54V, V82A L10I, I13A, K20R, A22V, E35D, M36I, N37D, K55R, R57K, Q61D, I62V, L63P, A71T, I72T, T74S, N83S, Q92K, I93LD
 194025194025JN670920PINAM46L, I54V, V82A, L90ML33F, K43T, G73SL10I, I13L, Q18E, K20R, E34Q, E35D, M36I, K55R, R57K, Q61N, I62V, L63P, A71V, I72T, I93LD
 194683194683JN670947PINAM46I, I54V, L76V, V82A, L90M L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I72T, I93LD
 195176195176JN670967PINAI54V, V82A, L90ML33LI, L89LVL10I, I13V, K14R, K20IM, E35D, M36I, N37D, R41K, Q61N, L63P, A71T, I72TD
 195598195598JN670988PINAM46I, V82A L10V, E35D, M36I, R41K, R57K, Q61D, L63T, E65D, I72T, V77ID
 195946195946JN671004PINAI54V, V82A L10V, I15V, K20R, E35D, M36I, N37D, R41K, Q61D, L63P, I93LD
 196487196487JN671026PINAM46I, I54V, L76V, V82AQ58EL10V, I15V, L19LI, K20R, M36I, R41K, D60DE, I62V, L63LP, I64IV, L89MD
 198096198096JN671100PINAM46L, I54V, V82A, L90MF53L, Q58E, T74PL10I, I15V, G16A, K20R, E35D, M36I, R41K, I62V, L63P, A71V, I85V, I93LD
 199016199016JN671148PINAG48V, I54V, V82A L10I, I15V, K20R, E35D, M36I, R41K, R57K, D60E, Q61E, L63P, I72TD
 203943203943JN671324PINAV32I, M46I, I54V, V82AL24I, L33F, K43T, F53LL10I, I13V, G16E, K20R, E35D, M36I, N37D, P39PS, R57K, Q61N, L63S, E65D, K70Q, A71V, T74S, V77I, L89TD
Van Zyl (2013)4782100KC423617LPV156M46I, I54V, L76LV, V82AQ58EL10V, T12P, I13V, G16GE, K20R, M36I, R41K, Q61QR, I64V, P79PHD