<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation V77I
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 22
Isolates 25
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG8181_w56 NFV55D30NN88DI13V, R41K, L63P, A71T, V77ID
Dumans (2004)268268AY390063SQV, RTV, NFV239  I13V, K55R, L63P, V77I, T91I, I93LD
Gomez-Carrillo (2004)9881798817AY365582PINAD30N N37A, R41K, L63C, V77ID
Montes (2004)MB_patMOL00_MOLL719AJ577953SQV, RTV, IDV, NFV143D30N Q7E, E35D, M36I, P39Q, R41K, I62V, L63P, I64L, A71V, I72V, V77I, I93LD
 MB_patDER02_DER736AJ577878NFV179D30NN88DL10Y, I13V, E35D, M36I, I62V, L63P, I64V, T74S, V77ID
Non-B Workgroup (2005)TK1003TK1003 IDV, SQV, RTV100  I13V, I15V, R41K, I62IV, I64V, E65D, V77ID
  TK1003a IDV, SQV, RTV100  I13V, I15V, R41K, I62V, I64V, E65D, V77ID
 TK1028TK1028 RTV, IDV, NFV207M46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028a RTV, IDV, NFV231M46I, I54V, V82TL24IP1PS, L10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028b RTV, IDV, NFV308M46L, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 TK2014TK2014 SQV, RTV, IDV, NFV307M46L, I54V, V82A L10V, R41K, D60E, L63P, I66IF, A71V, T74S, V77ID
 TK4014TK4014 SQV, RTV, NFV98  T12TP, I13V, I15IV, K20R, M36MI, R41K, L63H, I64V, I72IV, V77ID
 TK5006TK5006 SQV, RTV, NFV79L90MQ58EL10I, R41K, L63A, I64V, I72V, V77I, I93LD
Weber (2005)F75744F75744AY677393NFV76  I13V, R41K, D60E, L63LP, I64V, H69HY, V77ID
Baxter (2006)48-12251225-30417DQ877757PINAI84V, L90LM Q7E, L10I, G16GE, P39S, R41K, D60E, L63P, I64V, V77I, I85IVD
 48-14291429-30424DQ877819PINAM46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 48-33733373-30620DQ878231PINAM46L, G48V, I54V, V82A L10V, I15V, L19I, R41K, I62V, L63S, I64L, V77ID
Dau (2010)07823A07823AGU581871PINAM46I, L90M L10V, I13V, N37A, K55R, R57K, I62V, L63P, I64IV, I72IT, T74S, V77I, L89LM, I93LD
Aulicino (2011)444-O288CCR444-O288CCRHQ158164PINAD30NN88DL10I, I13V, I15V, K20T, E35N, M36I, R41K, Q61N, L63P, I72T, T74M, V77I, I93LD
Jones (2012)159280159280JN669947PINA  L10V, T12I, E35D, M36I, R41K, R57K, Q61N, I72M, V77ID
 187807187807JN670741PINAM46L, I54V, V82A, L90ML33F, K43T, G73SQ7QH, L10V, I13V, K20R, E35D, M36I, L38LS, R41K, I62V, L63P, H69R, A71T, I72T, V77ID
 193544193544JN670904PINAI54LK43T, F53FL, G73ST12K, I13V, I15V, K20T, E35D, M36I, N37S, R41K, R57K, Q61D, I62V, L63P, E65ED, H69HY, A71T, I72R, T74S, V77I, I93IMD
 195598195598JN670988PINAM46I, V82A L10V, E35D, M36I, R41K, R57K, Q61D, L63T, E65D, I72T, V77ID
 203943203943JN671324PINAV32I, M46I, I54V, V82AL24I, L33F, K43T, F53LL10I, I13V, G16E, K20R, E35D, M36I, N37D, P39PS, R57K, Q61N, L63S, E65D, K70Q, A71V, T74S, V77I, L89TD
Reynolds (2012)G0715G0715-2JN652208LPV   L10V, I13V, R41K, R57K, I64V, T74S, V77ID