<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation V77I
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 36
Isolates 39
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG8181_w56 NFV55D30NN88DI13V, R41K, L63P, A71T, V77ID
Montes (2004)MB_patMOL00_MOLL719AJ577953SQV, RTV, IDV, NFV143D30N Q7E, E35D, M36I, P39Q, R41K, I62V, L63P, I64L, A71V, I72V, V77I, I93LD
Non-B Workgroup (2005)TK1003TK1003 IDV, SQV, RTV100  I13V, I15V, R41K, I62IV, I64V, E65D, V77ID
  TK1003a IDV, SQV, RTV100  I13V, I15V, R41K, I62V, I64V, E65D, V77ID
 TK1028TK1028 RTV, IDV, NFV207M46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028a RTV, IDV, NFV231M46I, I54V, V82TL24IP1PS, L10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028b RTV, IDV, NFV308M46L, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 TK2014TK2014 SQV, RTV, IDV, NFV307M46L, I54V, V82A L10V, R41K, D60E, L63P, I66IF, A71V, T74S, V77ID
 TK3013TK3013 SQV, NFV205L90MG73SL10V, R41K, L63P, A71I, V77I, L89M, I93LD
 TK4014TK4014 SQV, RTV, NFV98  T12TP, I13V, I15IV, K20R, M36MI, R41K, L63H, I64V, I72IV, V77ID
 TK5006TK5006 SQV, RTV, NFV79L90MQ58EL10I, R41K, L63A, I64V, I72V, V77I, I93LD
Weber (2005)F43587F43587AY677390NFV27 Q58EI15V, E35D, N37D, R41K, I62V, L63A, A71T, V77ID
 F75744F75744AY677393NFV76  I13V, R41K, D60E, L63LP, I64V, H69HY, V77ID
 F55140F55140AY677472RTV, NFV197M46I, L90MQ58QEI13V, R41K, I62IV, L63Q, I64V, T74K, V77ID
Baxter (2006)48-12251225-30417DQ877757PINAI84V, L90LM Q7E, L10I, G16GE, P39S, R41K, D60E, L63P, I64V, V77I, I85IVD
 48-14291429-30424DQ877819PINAM46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 48-60286028-30409DQ878627PINAI54V, V82F, L90MV11VI, L33LF, F53LL10V, I13IV, R41K, K45V, I62V, L63P, H69K, A71V, I72V, T74A, V77ID
Waleria-Aleixo (2008)08RJ06051308RJ060513FJ591705PINA  E35D, M36I, R41K, L63P, A71V, V77I, I93LD
Kouri (2012)CU691-09CU691-09JQ585261PINAD30N, V32I, M46I, I47V, I54L, V82AL10LF, L33F, F53FL, Q58E, N88DI13V, I15V, L19I, K20R, E35D, M36L, N37T, R41T, K45R, D60E, L63P, H69Q, K70R, I72V, V77I, L89FD
 CU1270-09CU1270-09JQ585285PINA  I15V, G16E, K20M, P39S, R41K, K43R, Q61N, L63P, V77ID
 CU116-10CU116-10JQ585365PINA  E35D, M36I, R41K, K43R, R57K, I62V, L63P, I64V, H69Q, A71T, V77I, I93LD
 CU163-10CU163-10JQ585454PINA  Q2H, L10V, I13V, E35D, M36I, R41K, K45R, R57K, D60E, L63P, H69Q, V77ID
 CU645-09CU645-09JQ585259PINA  L19I, E35D, M36I, R41K, L63P, V77ID
 CU90-10CU90-10JQ585361PINAI50V, I54L, L90ML10F, L33F, K43T, F53L, L89VQ2P, L5F, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37G, R41K, D60E, L63P, H69HY, A71IV, V77I, V82I, I93ILD
 CU54-11CU54-11JQ585475PINA  R8RL, I13V, L19T, R41K, R57K, D60E, Q61E, L63P, V77ID
 CU311-10CU311-10JQ585381PINAI50V, I54L, L90ML33F, K43T, F53L, L89VV11L, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37D, R41K, D60E, L63P, H69Y, A71I, V77I, V82ID
Reynolds (2012)G0715G0715-2JN652208LPV   L10V, I13V, R41K, R57K, I64V, T74S, V77ID
Diaz (2015)RenG17128RenG17128KT748156PINAM46I, I50V, L76V, V82AL23LI, V32A, L33F, Q58ET12K, I13V, I15V, L19V, K20T, E34A, E35D, M36I, N37E, R41K, I62IV, I64V, K70R, V77I, L89LIMD
 RenG16632RenG16632KT747660PINAD30N, L90LML23I, L33F, F53L, N88DI13V, K14KR, I15V, K20V, E35G, R41K, D60E, L63P, A71I, T74S, V77I, L89I, I93LD
 RenG15468RenG15468KT746496PINA  Q7E, L10I, K14R, E35D, M36I, R41K, L63S, I64V, I72V, V77I, I93LD
 RenG14314RenG14314KT745342PINA G73GSQ7E, L10I, R41K, D60DE, I62V, L63P, I72V, V77I, I93LD
 RenG13110RenG13110KT744138PINA  R41K, L63P, E65D, V77I, I93LD
 RenG10992RenG10992KT742020PINA  Q7E, T12TP, K14R, E35D, M36I, N37D, R41K, L63P, I64L, A71V, I72IV, V77I, I93LD
 RenG10884RenG10884KT741912PINAD30N, I54V, V82A, L90ML10F, L33F, F53L, N88DI13V, I15V, G17D, L19I, K20T, E35N, M36I, N37E, R41T, K45V, D60E, Q61N, L63P, K70R, V77I, L89FD
 RenG10974RenG10974KT742002PINA  I15V, G16E, M36I, R41K, V77ID
 RenG10528RenG10528KT741556PINA  Q7E, R41K, L63P, I72IV, V77I, I93LD
Neogi (2016)61613.ZA.EC689KT592845LPV   I13IV, K14KR, N37S, R41K, R57K, L63Q, I64V, H69HY, V77ID
Svard (2017)2nd_20332nd_2033KX775278LPV142  I13V, R41K, Y59H, Q61N, I64V, V77ID
 2nd_50192nd_5019KX775288LPV328  T12P, K14R, L19S, R41K, A71T, I72V, V77ID