<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation T74S
Rx PI-naive
IncludeMixtures No
References 8
Patients 13
Isolates 14
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Hattori (2010)C08-2069156C08-2069156AB868303None   L10T, E35D, M36I, Q61E, L63P, H69K, T74S, V77ID
Florea (2011)105_2008105_2008JQ083016None   L10V, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, L63T, E65D, I72T, T74S, L89MD
 4638_20084638_2008JQ083062None   L10V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, T74S, L89MD
Hamers (2011)CP076303180CP076303180HQ994196None   K14G, I15V, K20R, M36I, R41K, I62V, L63V, E65D, H69K, I72V, T74S, L89MD
Reynolds (2012)G0715G0715-0JN652158None   L10V, I13V, R41K, R57RK, L63LV, I64V, I72IV, T74S, V77ID
  G0715-1JN652194None   L10V, I13V, Q18QR, R41K, R57K, I64V, T74S, V77ID
Bila (2013)MZ10-262HIV-1KF927351None   L19I, M36I, R41K, K43KR, L63V, H69K, T74S, L89M, I93LD
Frentz (2013)EHR-20296EHR-20296JX299872None   L10V, I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, T74S, L89MD
 EHR-49656EHR-49656JX300366None   T12N, I15V, L19I, K20R, E35D, M36I, R41K, R57K, L63T, I72T, T74S, L89MD
 EHR-64659EHR-64659JX300626None   L10V, I15V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, L63T, E65D, I72T, T74S, L89MD
Kiptoo (2013)KAP066KAP066KC516924None   L10V, I13V, R41K, T74SD
Temereanca (2013)SR6SR6JX966526None   L10I, T12K, I13V, I15V, K20I, E35D, M36I, R41K, R57K, L63T, E65D, I72V, T74S, L89MD
 SR60SR60JX966527None   L10V, I13V, I15V, G16E, K20R, M36I, R41K, R57K, L63T, E65D, T74S, V82I, L89MD
 SR66SR66JX966532None   L10V, I15V, E35D, M36I, R41K, V56G, R57K, L63T, E65D, A71N, I72T, T74S, L89MD