<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation G73S
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 28
Isolates 28
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Rousseau (2000)MNR18MNRMP1263AJ405965SQV, NFV69I84V, L90MG73SL10I, L19T, K20R, E35D, M36I, N37D, I62V, L63P, H69Y, A71T, I72TD
Montes (2004)MB_patESTU01_ESTU702AJ577887SQV, RTV, NFV, IDV309M46I, I84V, L90MV11I, G73SL10V, I13V, K20I, L33V, I62V, L63PD
Non-B Workgroup (2005)TK4015TK4016a NFV31 G73S, L89VT12E, K14R, I15V, L19I, R41KD
 TK4016TK4016a IDV, RTV275 G73S, L89VT12E, K14R, I15V, L19I, R41KD
Jones (2012)127508127508JN669438PINAI54V, V82A, L90ML33I, F53L, G73SL10I, I13V, K20R, E35D, M36I, R41K, K43KE, K55R, R57K, D60EK, Q61N, I62IV, L63P, A71IV, I72V, G94GD, C95LD
 187807187807JN670741PINAM46L, I54V, V82A, L90ML33F, K43T, G73SQ7QH, L10V, I13V, K20R, E35D, M36I, L38LS, R41K, I62V, L63P, H69R, A71T, I72T, V77ID
 193544193544JN670904PINAI54LK43T, F53FL, G73ST12K, I13V, I15V, K20T, E35D, M36I, N37S, R41K, R57K, Q61D, I62V, L63P, E65ED, H69HY, A71T, I72R, T74S, V77I, I93IMD
 194025194025JN670920PINAM46L, I54V, V82A, L90ML33F, K43T, G73SL10I, I13L, Q18E, K20R, E34Q, E35D, M36I, K55R, R57K, Q61N, I62V, L63P, A71V, I72T, I93LD
Kouri (2012)CU25-10CU25-10JQ585358PINAM46L, I54V, V82A, L90ML33F, K43T, F53L, G73SL10V, I13V, L19LI, K20R, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71I, I93LD
Diaz (2015)RenG16786RenG16786KT747814PINAI54V, L90MF53L, G73SL10I, K14KE, I15V, K20R, E34EAD, E35D, M36I, R41K, L63P, A71VD
 RenG17129RenG17129KT748157PINAM46I, I54V, V82A, L90ML33F, K43T, F53L, G73SL10V, L19I, K20R, E35D, M36I, R41K, K55R, R57RK, I62V, L63P, C67L, H69Q, A71V, I72LD
 RenG16303RenG16303KT747331PINAL90ML33I, F53L, G73ST12I, I15V, Q18H, K20V, E35G, M36I, N37D, R41K, L63P, A71I, T74S, I85V, I93LD
 RenG17296RenG17296KT748324PINAV32I, M46I, I54V, L90ML33I, G73S, N83DL10I, I15IV, Q18E, K20R, E35N, M36I, R41K, R57K, Q61D, L63P, C67Y, G68E, H69Y, A71V, I72RD
 RenG17066RenG17066KT748094PINAI54L, L90MG73SI15IV, K20T, E35D, M36I, R41K, K45KR, L63P, A71VD
 RenG15928RenG15928KT746956PINAM46L, I54V, V82AL24I, Q58E, G73SL10I, T12N, I15V, L19P, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, L63P, A71V, I72LD
 RenG16495RenG16495KT747523PINAM46I, I50L, V82AQ58E, G73SL10V, L33V, E35D, M36I, N37S, R41K, K45R, D60E, I62V, L63P, I64V, I72L, I85VD
 RenG16182RenG16182KT747210PINAM46I, I54V, I84V, L90MV11I, G73SL10I, I13IV, I15V, K20KIM, E21Q, E35D, M36I, N37D, R57RK, D60DE, Q61N, L63P, H69HR, A71V, I72M, I85IV, I93LD
 RenG14273RenG14273KT745301PINAI50L, V82AL33F, K43KT, G73SL10V, I13V, I15V, K20M, E35G, M36I, R41K, K55KN, R57K, D60E, Q61N, I62V, L63P, A71AITV, I93LD
 RenG14584RenG14584KT745612PINAI54L, V82A, L90MV11I, L33F, K43T, F53L, G73SI13V, I15V, G16GCW, L19V, K20R, E21G, L24F, E35D, M36I, N37T, R41K, K55R, R57K, D60E, Q61H, I62V, L63P, A71V, I72FD
 RenG14898RenG14898KT745926PINAM46I, I54V, I84V, L90MV11I, G73SL10IM, T12P, K14*, I15V, L19P, K20I, E35D, M36I, N37D, D60DE, Q61N, L63P, H69HR, A71V, I72M, I85V, I93LD
 RenG13674RenG13674KT744702PINAV82A, L90ML33F, K43T, G73SL10V, I13V, I15V, L19I, K20T, E35D, M36I, R41K, L63P, A71V, T74S, V77I, I93LD
 RenG12682RenG12682KT743710PINA F53L, G73SL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57RK, I62IV, L63LP, I64IV, A71AVD
 RenG12015RenG12015KT743043PINAG48A, I54V, V82A, L90MG73SL10I, K14R, I15V, E35ED, R41K, L63P, I64IV, A71V, I85VD
 RenG12872RenG12872KT743900PINAM46L, I54V, I84V, L90ML10F, V11VI, Q58E, G73SI15V, K20KM, M36I, N37E, R41K, K55R, R57RK, I62V, L63P, A71V, N83SD
 RenG12091RenG12091KT743119PINAM46I, I54V, V82A, L90MG73S, L89VL10V, I13V, K20T, L33L_L, M36I, R41K, K55R, I62IV, L63P, I64IL, A71V, I93L, N98ID
 RenG10617RenG10617KT741645PINAV32I, M46I, I47V, I54V, V82A, L90MV11I, L33F, G73S, L89VL10V, I13V, I15V, L19P, K20R, M36I, N37D, K55R, R57K, I62V, L63P, I64L, A71V, I72VD
 RenG11414RenG11414KT742442PINAL90ML23I, F53L, G73SL10V, T12S, I15V, K20R, E35D, M36IV, N37NT, R41K, K45R, I62V, L63P, C67F, A71I, I72LD
 RenG10051RenG10051KT741079PINAL90ML23I, F53L, G73SL10LI, K14KN, I15V, K20T, E34EQ, E35D, M36I, R41K, K45R, I62IV, L63P, I66IV, A71IL, I72T, V77I, I93LD