<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation A71V
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 39
Isolates 41
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Monno (2003)ML_Pat89ML_Pat89 PINAI54IV, I84V, L90MG73TL10I, I15V, G16E, L19Q, K20M, I62V, L63N, A71V, I72T, P79D, I93LD
Montes (2004)MB_patMOL00_MOLL719AJ577953SQV, RTV, IDV, NFV143D30N Q7E, E35D, M36I, P39Q, R41K, I62V, L63P, I64L, A71V, I72V, V77I, I93LD
Non-B Workgroup (2005)TK1028TK1028 RTV, IDV, NFV207M46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028a RTV, IDV, NFV231M46I, I54V, V82TL24IP1PS, L10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028b RTV, IDV, NFV308M46L, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 TK2001TK2001 SQV, RTV, NFV94M46I, I84VN83DL10I, I13V, A22V, E35G, M36I, I62V, L63P, I64V, A71V, I93LD
 TK2014TK2014 SQV, RTV, IDV, NFV307M46L, I54V, V82A L10V, R41K, D60E, L63P, I66IF, A71V, T74S, V77ID
Baxter (2006)12-11341134-30326DQ876024PINAV32I, M46I, I47V, I54M, I84V, L90ML10F, L33F, L89VI13V, I15V, K20T, M36I, N37S, R41K, L63P, A71V, G73D, I93LD
 12-17561756-30527DQ876870PINAI54V, V82A, L90MK43T, G73SL10I, I15V, K20R, E35D, M36I, I62V, L63P, H69R, A71VD
 48-14291429-30424DQ877819PINAM46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 48-22442244-30722DQ877883PINAV32I, M46I, I54V, V82A, L90MK43T, G73TL10V, I15V, K20R, M36I, R41N, K55R, D60E, L63P, H69HR, K70R, A71V, I93L, C95VD
 48-30563056-30318DQ877968PINAM46I, I54V, L76V, V82TL10F, L89VI13V, K20M, M36I, R41K, I62V, L63P, A71V, I72V, I93LD
 48-30833083-30313DQ877992PINAV32I, M46I, I47V, I54V, V82A, L90MK43T, F53L, G73S, L89VL10V, T12I, I13V, G16A, K20I, M36I, K55R, L63P, A71VD
 48-41654165-30410DQ878398PINAM46MI, I54V, V82SL24IL10I, I13V, L19I, K20IM, M36I, R41K, L63P, A71VD
 48-60286028-30409DQ878627PINAI54V, V82F, L90MV11VI, L33LF, F53LL10V, I13IV, R41K, K45V, I62V, L63P, H69K, A71V, I72V, T74A, V77ID
 48-61576157-30704DQ878733PINAG48A, I54V, V82A, I84V, L90ML33F, Q58E, G73GS, L89LVT4S, L10I, K20R, E35D, M36L, R57RK, I62V, L63P, A71V, I72ILM, Q92KD
 48-71347134-30729DQ878972PINAV32I, M46L, V82A, L90MK43T, L89VI13V, K20R, M36I, I62V, L63P, A71VD
 48-90069006-30923DQ877670PINAI54A, V82AL24I, Q58E, L89VL10Y, I13IMV, I15V, K20I, E34KQ, E35D, M36I, N37NS, R41K, R57K, D60E, I62IV, L63P, A71V, I93LD
Waleria-Aleixo (2008)08PR06072008PR060720FJ591542PINAI54V, V82TL24I, F53LL10V, I13V, K20R, E35D, M36V, N37T, R41K, R57K, I62V, L63P, I64V, A71V, T74SD
 08PR06075308PR060753FJ591549PINAV32I, M46MI, I54V, L90ML33I, K43T, F53LL10V, I13V, G16E, L19LI, K20M, E35EG, M36I, L63R, I66F, H69R, A71V, I72IVD
 08RJ06060708RJ060607FJ591767PINAM46I, I54V, I84V, L90ML10F, L33F, T74PK20I, E35N, M36I, N37DE, I62V, L63P, I64M, C67F, H69K, A71V, I72V, T91TS, Q92KD
 08RJ06051308RJ060513FJ591705PINA  E35D, M36I, R41K, L63P, A71V, V77I, I93LD
Jones (2012)200084200084JN671190PINAM46I, I54IV, I84V, L90ML33F, K43KT, T74PL10I, I13V, K20KR, M36I, R41RK, K55KR, I62V, L63P, H69K, K70KT, A71V, T91SD
Kouri (2012)CU1373-09CU1373-09JQ585294PINAV32I, M46L, L76V, V82AL10F, L33F, L89VI13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92KD
 CU373-10CU373-10JQ585388PINAM46I, I54V, L76V, V82AL24I, L33FL10I, I13V, K20R, E35D, M36I, N37D, R41K, D60E, I62V, L63P, A71V, I93LD
 CU1627-09CU1627-09JQ585302PINAI54V, V82A, I84V, L90M L10I, K20I, E35G, M36I, R41K, D60E, I62V, L63P, H69HQ, A71VD
 CU1805-09CU1805-09JQ585313PINAM46I, I54V, V82A, L90M L10I, K20I, M36I, N37D, R41K, K43KR, Q61N, L63P, I64L, H69Q, A71V, I72IV, I93LD
 CU461-09CU461-09JQ585253PINAI54V, L90MG73SL10I, K20R, E35D, M36I, R41K, I62V, L63P, H69Q, A71V, I93LD
 CU1288-09CU1288-09JQ585288PINAV32I, M46L, L76V, V82AL33LF, L89VL10I, I13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92KD
 CU1209-09CU1209-09JQ585279PINAM46L, I54M, V82AL10F, L24I, L33F, Q58EI13V, K20R, M36I, R41K, K43KR, I62V, L63P, E65ED, A71VD
 CU1959-09CU1959-09JQ585326PINAM46L, I54L, V82T, L90ML33F, T74PL10I, I13V, E35D, M36I, R41K, K43R, K55R, L63P, H69Q, A71V, I93LD
Diaz (2015)RenG15645RenG15645KT746673PINAM46I, I54V, I84V, L90ML10F, F53L, T74PI13V, K20R, E35D, M36I, R41K, K55H, R57K, L63P, H69R, A71V, L89I, T91S, Q92KD
 RenG16432RenG16432KT747460PINAI50L, N88SQ58EL10V, G16E, K20R, E35D, M36I, N37T, L63T, E65ED, H69K, A71V, I72T, L89M, I93LD
 RenG16876RenG16876KT747904PINAI50L, V82AL33FI13V, K20KT, E35D, M36I, R41K, L63A, A71V, T91SD
 RenG15295RenG15295KT746323PINAV32I, M46I, I47V, I50V, I54L, L90MK43T, L89VT12K, I15V, L19I, K20T, E35D, M36I, N37E, R57K, A71V, I85VD
 RenG12426RenG12426KT743454PINAM46I, I54V, V82S, I84VK43T, L89VL10I, I15V, L19IV, K20R, M36I, I62IV, L63P, K70R, A71V, I72M, Q92KD
 RenG12659RenG12659KT743687PINAI50L, L90MG73SK14R, I15V, G17D, K20T, E35DN, M36I, R41K, K45R, R57K, Q61N, L63P, A71VD
 RenG12091RenG12091KT743119PINAM46I, I54V, V82A, L90MG73S, L89VL10V, I13V, K20T, L33L_L, M36I, R41K, K55R, I62IV, L63P, I64IL, A71V, I93L, N98ID
 RenG10992RenG10992KT742020PINA  Q7E, T12TP, K14R, E35D, M36I, N37D, R41K, L63P, I64L, A71V, I72IV, V77I, I93LD
 RenG11099RenG11099KT742127PINAM46L, I54V, L76V, V82A, L90M L10V, I15V, K20R, M36I, N37D, R41K, I62V, L63P, I64V, H69R, A71V, I72V, I85V, I93LD
 RenG11511RenG11511KT742539PINAI54V, V82AL10F, N88DT12K, I15V, L19I, K20T, E35D, M36I, N37EK, R41N, R57RK, D60E, L63P, A71VD