<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation A71V
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 67
Isolates 70
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Monno (2003)ML_Pat89ML_Pat89 PINAI54IV, I84V, L90MG73TL10I, I15V, G16E, L19Q, K20M, I62V, L63N, A71V, I72T, P79D, I93LD
Gomez-Carrillo (2004)9827298272AY365573PINAI54V, I84V, L90ML33F, T74PL10I, L19V, I62V, L63P, H69Q, A71V, T91SD
Machado (2004)cs232cs232AY502101Unknown, NFVNAI84V, L90MG73SL10I, E35D, M36I, R41K, L63P, A71VD
Montes (2004)MB_patMOL00_MOLL719AJ577953SQV, RTV, IDV, NFV143D30N Q7E, E35D, M36I, P39Q, R41K, I62V, L63P, I64L, A71V, I72V, V77I, I93LD
Garcia-Bujalance (2005)GBS_40GBS_40AY872321NFV D30NL10F, N88DV11F, I13V, I15V, K20T, M36I, R41K, I62V, L63P, I64L, C67W, A71V, V77ID
Non-B Workgroup (2005)TK1028TK1028 RTV, IDV, NFV207M46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028a RTV, IDV, NFV231M46I, I54V, V82TL24IP1PS, L10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028b RTV, IDV, NFV308M46L, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 TK2001TK2001 SQV, RTV, NFV94M46I, I84VN83DL10I, I13V, A22V, E35G, M36I, I62V, L63P, I64V, A71V, I93LD
 TK2014TK2014 SQV, RTV, IDV, NFV307M46L, I54V, V82A L10V, R41K, D60E, L63P, I66IF, A71V, T74S, V77ID
 TK3005TK3005 SQV, IDV, NFV262L90MG73SL10I, G16A, R41K, K45R, Q61N, G68E, H69Q, A71V, V77I, I93LD
  TK3005a SQV, IDV, NFV262L90MG73SL10I, G16A, R41K, K45R, Q61N, G68E, H69Q, A71V, V77I, I93LD
Baxter (2006)12-11341134-30326DQ876024PINAV32I, M46I, I47V, I54M, I84V, L90ML10F, L33F, L89VI13V, I15V, K20T, M36I, N37S, R41K, L63P, A71V, G73D, I93LD
 12-10121012-30717DQ876218PINAV32I, M46I, I47V, I54M, I84V, L90ML10F, L33F, G73S, L89VI13V, I15V, L19I, K20T, E35D, M36I, R41N, F53Y, K55N, D60E, L63P, I64L, I66F, H69K, A71V, V77I, Q92K, T96SD
 12-17561756-30527DQ876870PINAI54V, V82A, L90MK43T, G73SL10I, I15V, K20R, E35D, M36I, I62V, L63P, H69R, A71VD
 48-14291429-30424DQ877819PINAM46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 48-22442244-30722DQ877883PINAV32I, M46I, I54V, V82A, L90MK43T, G73TL10V, I15V, K20R, M36I, R41N, K55R, D60E, L63P, H69HR, K70R, A71V, I93L, C95VD
 48-30563056-30318DQ877968PINAM46I, I54V, L76V, V82TL10F, L89VI13V, K20M, M36I, R41K, I62V, L63P, A71V, I72V, I93LD
 48-30833083-30313DQ877992PINAV32I, M46I, I47V, I54V, V82A, L90MK43T, F53L, G73S, L89VL10V, T12I, I13V, G16A, K20I, M36I, K55R, L63P, A71VD
 48-32573257-30710DQ878161PINAI54V, V82A, L90ML10F, V11I, Q58E, G73SI13V, I15V, K20I, M36I, D60E, Q61E, I62V, L63P, A71V, I72TD
 48-41454145-30530DQ878377PINAV32I, M46I, I54M, I84V, L90ML33F, K43T, G73S, L89VL10V, I13V, G16A, K20L, F53Y, D60E, L63P, I66F, A71V, I72L, P79ND
 48-41654165-30410DQ878398PINAM46MI, I54V, V82SL24IL10I, I13V, L19I, K20IM, M36I, R41K, L63P, A71VD
 48-50225022-30606DQ878556PINAM46I, I54V, L76V, I84V, L90ML10F, V11I, Q58E, G73A, L89VI13V, K20I, L33V, E35K, M36I, K55R, D60E, I62V, L63P, I64V, A71V, T91S, I93LD
 48-60286028-30409DQ878627PINAI54V, V82F, L90MV11VI, L33LF, F53LL10V, I13IV, R41K, K45V, I62V, L63P, H69K, A71V, I72V, T74A, V77ID
 48-61576157-30704DQ878733PINAG48A, I54V, V82A, I84V, L90ML33F, Q58E, G73GS, L89LVT4S, L10I, K20R, E35D, M36L, R57RK, I62V, L63P, A71V, I72ILM, Q92KD
 48-61816181-30721DQ878753PINAG48M, I50V, I54A, V82A L10I, L19I, K20R, M36I, N37D, I62V, L63P, I64M, A71V, I72V, Q92KD
 48-63726372-30930DQ878882PINAI54V, V82A, L90M L10V, I15V, K20R, M36I, R41K, I62V, L63P, A71V, I93LD
 48-71347134-30729DQ878972PINAV32I, M46L, V82A, L90MK43T, L89VI13V, K20R, M36I, I62V, L63P, A71VD
 48-90069006-30923DQ877670PINAI54A, V82AL24I, Q58E, L89VL10Y, I13IMV, I15V, K20I, E34KQ, E35D, M36I, N37NS, R41K, R57K, D60E, I62IV, L63P, A71V, I93LD
Waleria-Aleixo (2008)08PR06072008PR060720FJ591542PINAI54V, V82TL24I, F53LL10V, I13V, K20R, E35D, M36V, N37T, R41K, R57K, I62V, L63P, I64V, A71V, T74SD
 08PR05026608PR050266FJ591295PINAI50L T12Q, K14T, I15V, K20R, E35D, M36I, R41K, R57K, A71VD
 08PR06075308PR060753FJ591549PINAV32I, M46MI, I54V, L90ML33I, K43T, F53LL10V, I13V, G16E, L19LI, K20M, E35EG, M36I, L63R, I66F, H69R, A71V, I72IVD
 08RJ06060708RJ060607FJ591767PINAM46I, I54V, I84V, L90ML10F, L33F, T74PK20I, E35N, M36I, N37DE, I62V, L63P, I64M, C67F, H69K, A71V, I72V, T91TS, Q92KD
 08RJ06051308RJ060513FJ591705PINA  E35D, M36I, R41K, L63P, A71V, V77I, I93LD
Jones (2012)133389133389JN669521PINAI54L, I84VL33FL10I, K14R, E35D, M36I, R41K, D60E, L63P, A71V, I93LD
 178433178433JN670483PINAM46I, I54V, L76V, V82F, L90MQ58EL10I, K20R, E35D, M36I, D60E, Q61E, I62V, L63P, I64V, A71V, I72V, I93LD
 187443187443JN670732PINAG48A, I54V, V82A, I84VL33F, N83ND, L89VL10I, K14R, K20KR, E35D, M36I, R41K, D60E, L63P, A71V, T91S, Q92QR, I93LD
 191520191520JN670829PINA  T12E, I15V, L19I, E35D, R41K, L63P, H69HNPT, A71V, I85IT, I93LD
 200084200084JN671190PINAM46I, I54IV, I84V, L90ML33F, K43KT, T74PL10I, I13V, K20KR, M36I, R41RK, K55KR, I62V, L63P, H69K, K70KT, A71V, T91SD
Kouri (2012)CU1373-09CU1373-09JQ585294PINAV32I, M46L, L76V, V82AL10F, L33F, L89VI13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92KD
 CU373-10CU373-10JQ585388PINAM46I, I54V, L76V, V82AL24I, L33FL10I, I13V, K20R, E35D, M36I, N37D, R41K, D60E, I62V, L63P, A71V, I93LD
 CU1627-09CU1627-09JQ585302PINAI54V, V82A, I84V, L90M L10I, K20I, E35G, M36I, R41K, D60E, I62V, L63P, H69HQ, A71VD
 CU1805-09CU1805-09JQ585313PINAM46I, I54V, V82A, L90M L10I, K20I, M36I, N37D, R41K, K43KR, Q61N, L63P, I64L, H69Q, A71V, I72IV, I93LD
 CU461-09CU461-09JQ585253PINAI54V, L90MG73SL10I, K20R, E35D, M36I, R41K, I62V, L63P, H69Q, A71V, I93LD
 CU1288-09CU1288-09JQ585288PINAV32I, M46L, L76V, V82AL33LF, L89VL10I, I13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92KD
 CU1209-09CU1209-09JQ585279PINAM46L, I54M, V82AL10F, L24I, L33F, Q58EI13V, K20R, M36I, R41K, K43KR, I62V, L63P, E65ED, A71VD
 CU1959-09CU1959-09JQ585326PINAM46L, I54L, V82T, L90ML33F, T74PL10I, I13V, E35D, M36I, R41K, K43R, K55R, L63P, H69Q, A71V, I93LD
Diaz (2015)RenG16786RenG16786KT747814PINAI54V, L90MF53L, G73SL10I, K14KE, I15V, K20R, E34EAD, E35D, M36I, R41K, L63P, A71VD
 RenG16175RenG16175KT747203PINAM46I, I54V, V82S, L90MV11I, G73STL10I, T12P, I15V, G16A, L19Q, K20I, M36I, K45R, K55R, L63P, C67G, A71V, I72L, I85VD
 RenG16031RenG16031KT747059PINAL90MV11IL10I, I15V, L19Q, K20T, E35G, M36I, P39S, R41K, I62V, L63P, H69Y, A71V, I72L, T74SD
 RenG15645RenG15645KT746673PINAM46I, I54V, I84V, L90ML10F, F53L, T74PI13V, K20R, E35D, M36I, R41K, K55H, R57K, L63P, H69R, A71V, L89I, T91S, Q92KD
 RenG16880RenG16880KT747908PINAM46L, I54V, V82ML24I, F53LL10V, T12P, K20R, E35D, M36I, N37Q, R41K, L63P, A71V, V77I, I93LD
 RenG17066RenG17066KT748094PINAI54L, L90MG73SI15IV, K20T, E35D, M36I, R41K, K45KR, L63P, A71VD
 RenG16432RenG16432KT747460PINAI50L, N88SQ58EL10V, G16E, K20R, E35D, M36I, N37T, L63T, E65ED, H69K, A71V, I72T, L89M, I93LD
 RenG15641RenG15641KT746669PINAM46I, I54L, L76V, I84VL10F, V11VII13V, I15V, L19LQ, K20I, E35NS, M36I, R41K, K55KR, R57RK, D60E, Q61N, I62V, L63P, I64IV, A71V, I72V, N83NH, T91SD
 RenG16023RenG16023KT747051PINAV32I, M46L, I47V, I50L, V82A, I84VL33F, Q58ET12N, I13V, I15V, K20R, E35D, M36I, N37E, Q61QH, L63T, I64V, A71V, I72V, G78GV, R87RI, L89MD
 RenG16876RenG16876KT747904PINAI50L, V82AL33FI13V, K20KT, E35D, M36I, R41K, L63A, A71V, T91SD
 RenG16895RenG16895KT747923PINAM46I, I47V, I54V, V82A, L90MV11I, F53L, G73S, L89VL10IV, I13V, I15V, L19LAPV, K20I, E35G, M36I, L63P, A71V, I72L, Q92KD
 RenG15415RenG15415KT746443PINAM46I, N88SQ58EL10V, I13IV, I15V, K20T, K55KR, L63P, A71V, V77I, T91SD
 RenG13686RenG13686KT744714PINAM46I, I47V, I54V, V82F, L90MQ58EL10V, I13V, K20I, E35D, M36I, R41K, I62V, L63P, I64V, A71V, I93LD
 RenG14154RenG14154KT745182PINAM46MIL, I54V, V82FL33LIL10V, I13IV, I15V, K20RT, E35DN, M36I, R41K, Y59YH, D60DE, I62V, L63PS, I64IL, A71V, I72T, T74AS, V77VI, I93LD
 RenG12426RenG12426KT743454PINAM46I, I54V, V82S, I84VK43T, L89VL10I, I15V, L19IV, K20R, M36I, I62IV, L63P, K70R, A71V, I72M, Q92KD
 RenG12659RenG12659KT743687PINAI50L, L90MG73SK14R, I15V, G17D, K20T, E35DN, M36I, R41K, K45R, R57K, Q61N, L63P, A71VD
 RenG13053RenG13053KT744081PINAV32I, M46L, G48GV, I50IL, V82A, L90ML33F, G73GS, L89VL10I, I13V, L19I, L24LF, E34EQ, E35ED, M36I, N37S, R41K, K55HQ, I62IV, L63A, I64L, A71VD
 RenG12091RenG12091KT743119PINAM46I, I54V, V82A, L90MG73S, L89VL10V, I13V, K20T, L33L_L, M36I, R41K, K55R, I62IV, L63P, I64IL, A71V, I93L, N98ID
 RenG10992RenG10992KT742020PINA  Q7E, T12TP, K14R, E35D, M36I, N37D, R41K, L63P, I64L, A71V, I72IV, V77I, I93LD
 RenG11212RenG11212KT742240PINAD30N, I54LL10F, L33I, N83D, N88DI13V, K14R, A22V, E34N, M36I, N37D, L63P, H69K, A71V, I72V, T74SD
 RenG11287RenG11287KT742315PINAM46I, I54V, V82A, L90ML10F, K43T, G73TQ7DE, P9PL, I13M, I15V, K20I, E21EQ, E35N, M36I, R41RK, K55R, R57RK, I62IV, L63P, I64V, A71V, I72T, I85V, I93LD
 RenG10591RenG10591KT741619PINAL90ML23I, F53LL10I, T12K, I13L, I15V, L19Q, K20T, E35D, M36I, N37NADT, R41K, K55R, R57K, I62V, L63P, I66IV, A71V, T74S, V75ID
 RenG10617RenG10617KT741645PINAV32I, M46I, I47V, I54V, V82A, L90MV11I, L33F, G73S, L89VL10V, I13V, I15V, L19P, K20R, M36I, N37D, K55R, R57K, I62V, L63P, I64L, A71V, I72VD