<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation A71V
Rx >= 1 PI
IncludeMixtures No
References 12
Patients 101
Isolates 103
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Monno (2003)ML_Pat89ML_Pat89 PINAI54IV, I84V, L90MG73TL10I, I15V, G16E, L19Q, K20M, I62V, L63N, A71V, I72T, P79D, I93LD
Gomez-Carrillo (2004)101028101028AY365623PINAI54V, L76V, V82A L10I, I13V, I15V, K20M, E35D, M36I, R41K, Q61N, L63P, A71V, I72T, L89I, I93LD
 103136103136AY365669PINAD30N, V82AN83D, N88DL10I, I13V, A22V, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, A71VD
 113575113575AY365879PINAD30N E35D, M36I, N37T, R41RK, L63C, I64V, A71V, I93LD
Montes (2004)MB_patMOL00_MOLL719AJ577953SQV, RTV, IDV, NFV143D30N Q7E, E35D, M36I, P39Q, R41K, I62V, L63P, I64L, A71V, I72V, V77I, I93LD
Non-B Workgroup (2005)TK1028TK1028 RTV, IDV, NFV207M46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028a RTV, IDV, NFV231M46I, I54V, V82TL24IP1PS, L10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028b RTV, IDV, NFV308M46L, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 TK2001TK2001 SQV, RTV, NFV94M46I, I84VN83DL10I, I13V, A22V, E35G, M36I, I62V, L63P, I64V, A71V, I93LD
 TK2014TK2014 SQV, RTV, IDV, NFV307M46L, I54V, V82A L10V, R41K, D60E, L63P, I66IF, A71V, T74S, V77ID
Baxter (2006)48-14291429-30424DQ877819PINAM46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 48-22442244-30722DQ877883PINAV32I, M46I, I54V, V82A, L90MK43T, G73TL10V, I15V, K20R, M36I, R41N, K55R, D60E, L63P, H69HR, K70R, A71V, I93L, C95VD
 48-30563056-30318DQ877968PINAM46I, I54V, L76V, V82TL10F, L89VI13V, K20M, M36I, R41K, I62V, L63P, A71V, I72V, I93LD
 48-41654165-30410DQ878398PINAM46MI, I54V, V82SL24IL10I, I13V, L19I, K20IM, M36I, R41K, L63P, A71VD
Cardoso (2009)3117BRGO3117FJ638454PINAM46I, I54V, L76V, V82A, L90ML33FL10V, I13V, I15V, K20R, E35D, M36I, K55R, R57K, D60E, I62V, L63P, A71V, I72V, I93LD
Dau (2010)07867A07867AGU581877PINAV32I, M46I, I47A, L90ML10F, L89VT4A, I13V, K20T, L33V, I62V, L63P, H69Y, A71V, I93LD
 09705A09705AGU581977PINAM46L, I54V, V82AT, I84V, L90ML33F, F53L, L89VL10I, I13V, I15V, K20T, E35D, M36I, N37D, K55R, D60E, I62V, L63P, I66F, K70E, A71V, Q92KD
Aulicino (2011)ARL636VSQARL636VSQFJ525813PINAM46I, I47V, I54V, V82AL24I, L33F, K43T, F53L, Q58EL10V, G16A, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71V, I93LD
 ARN394FGLARN394FGLFJ525858PINAI54V, V82A, L90M L10V, K20R, E35D, M36I, N37D, R41K, R57K, Q61D, I62V, L63V, A71V, I72V, T74SD
 476-O345RMS476-O345RMSHQ158190PINA  G16E, E35D, M36I, R41K, R57K, Q61N, I62T, L63T, A71V, I72M, I93LD
El Annaz (2012)1365013650.PRJN185268IDV52M46L, I54A, V82A L10I, K20R, E35D, M36I, N37D, R57K, L63P, I64V, K70T, A71V, I93LD
Jones (2012)129393129393JN669468PINAV82A, L90MN88DL10I, I13A, A22V, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, A71VD
 133389133389JN669521PINAI54L, I84VL33FL10I, K14R, E35D, M36I, R41K, D60E, L63P, A71V, I93LD
 147583147583JN669693PINAI54V, V82T, L90M L10I, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, L63A, E65D, A71V, T74S, I93LD
 159279159279JN669946PINAI47V, I54V, V82A, L90ML33F, G48W, F53L, Q58EL10V, I13V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, C67E, A71V, I93LD
 159787159787JN669960PINAI54V L10V, I13V, K20R, E35D, M36I, R41K, R57K, Q61N, I64IV, A71V, I72T, T74S, Q92R, I93LD
 162069162069JN670025PINAL90M L10V, I13V, I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, L63P, A71V, T74S, I93LD
 166308166308JN670124PINAM46I, I54V, V82TL33F, L76IL10V, T12Q, I13V, I15V, L19I, K20KR, E35D, M36IL, R41K, K55R, R57K, Q61N, L63P, I64V, A71V, T74SD
 171784171784JN670271PINAI54IV, V82A, L90ML33LFL10V, I13V, K20KR, E35D, M36I, R41K, R57K, Q61D, I62V, L63PT, A71V, I72T, T74S, I93LD
 172862172862JN670305PINAM46L, I54V, V82A, L90ML33FL10V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63P, I64L, A71V, Q92K, I93LD
 175531175531JN670363PINAM46L, I54IV, V82AL24I, L33LFL10V, I15V, K20M, E35DN, M36I, N37D, R41K, K55KR, R57K, Q61D, A71V, I72TD
 176324176324JN670393PINAD30N K20T, E35D, M36I, N37D, K45Q, R57K, D60E, Q61D, L63A, A71V, I93LD
 178114178114JN670471PINAI54V, V82A, L90M L10V, K20R, M36I, R41K, R57K, Q61N, L63A, A71V, T74S, I93LD
 178433178433JN670483PINAM46I, I54V, L76V, V82F, L90MQ58EL10I, K20R, E35D, M36I, D60E, Q61E, I62V, L63P, I64V, A71V, I72V, I93LD
 184334184334JN670676PINAG48V, L90M L10I, L19Q, K20R, E35D, M36I, N37NT, R41K, R57K, D60E, Q61D, I62V, L63P, A71V, I72T, V82I, I85V, I93LD
 185641185641JN670705PINAI54LV, V82T, L90ML33F, F53FL, T74PSL10I, I13V, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, L63AT, E65D, A71V, I72V, T80TI, L89LM, I93LD
 187220187220JN670729PINAM46L, I54V, I84V, L90MG48E, L89VL10I, I13V, K20MT, E35D, M36I, R57K, Q61N, I62V, L63P, C67Y, G68E, H69Y, A71V, Q92K, I93LD
 187443187443JN670732PINAG48A, I54V, V82A, I84VL33F, N83ND, L89VL10I, K14R, K20KR, E35D, M36I, R41K, D60E, L63P, A71V, T91S, Q92QR, I93LD
 194025194025JN670920PINAM46L, I54V, V82A, L90ML33F, K43T, G73SL10I, I13L, Q18E, K20R, E34Q, E35D, M36I, K55R, R57K, Q61N, I62V, L63P, A71V, I72T, I93LD
 194683194683JN670947PINAM46I, I54V, L76V, V82A, L90M L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I72T, I93LD
 198096198096JN671100PINAM46L, I54V, V82A, L90MF53L, Q58E, T74PL10I, I15V, G16A, K20R, E35D, M36I, R41K, I62V, L63P, A71V, I85V, I93LD
 200084200084JN671190PINAM46I, I54IV, I84V, L90ML33F, K43KT, T74PL10I, I13V, K20KR, M36I, R41RK, K55KR, I62V, L63P, H69K, K70KT, A71V, T91SD
 201210201210JN671216PINAI54V, V82T, I84VL33F, F53LL10I, I15V, K20R, E35D, M36I, N37D, R41K, Q61N, L63S, I64L, A71V, I72T, T74S, I85V, L89M, I93LD
 203943203943JN671324PINAV32I, M46I, I54V, V82AL24I, L33F, K43T, F53LL10I, I13V, G16E, K20R, E35D, M36I, N37D, P39PS, R57K, Q61N, L63S, E65D, K70Q, A71V, T74S, V77I, L89TD
 205418205418JN671361PINAD30N K20T, E35DN, M36I, N37D, K45Q, R57K, D60E, Q61DN, L63A, A71V, I93IL, F99FSD
 207305207305JN671429PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, K20T, E35D, M36I, R41K, D60E, Q61N, I62V, L63T, I64L, C67D, A71V, I72T, I93LD
 207507207507JN671437PINA  I15V, E35D, M36I, R41K, I62V, L63P, H69Y, A71V, I93LD
Kouri (2012)CU1373-09CU1373-09JQ585294PINAV32I, M46L, L76V, V82AL10F, L33F, L89VI13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92KD
 CU373-10CU373-10JQ585388PINAM46I, I54V, L76V, V82AL24I, L33FL10I, I13V, K20R, E35D, M36I, N37D, R41K, D60E, I62V, L63P, A71V, I93LD
 CU263-10CU263-10JQ585374PINAV32I, I54M, I84VV11I, L33F, F53FLQ2L, L5LF, L10V, I13V, K14E, I15V, G17D, K20R, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, L63P, I64V, A71V, T74E, V82ID
 CU1627-09CU1627-09JQ585302PINAI54V, V82A, I84V, L90M L10I, K20I, E35G, M36I, R41K, D60E, I62V, L63P, H69HQ, A71VD
 CU1805-09CU1805-09JQ585313PINAM46I, I54V, V82A, L90M L10I, K20I, M36I, N37D, R41K, K43KR, Q61N, L63P, I64L, H69Q, A71V, I72IV, I93LD
 CU1209-09CU1209-09JQ585279PINAM46L, I54M, V82AL10F, L24I, L33F, Q58EI13V, K20R, M36I, R41K, K43KR, I62V, L63P, E65ED, A71VD
 CU1959-09CU1959-09JQ585326PINAM46L, I54L, V82T, L90ML33F, T74PL10I, I13V, E35D, M36I, R41K, K43R, K55R, L63P, H69Q, A71V, I93LD
Diaz (2015)RenG16786RenG16786KT747814PINAI54V, L90MF53L, G73SL10I, K14KE, I15V, K20R, E34EAD, E35D, M36I, R41K, L63P, A71VD
 RenG16175RenG16175KT747203PINAM46I, I54V, V82S, L90MV11I, G73STL10I, T12P, I15V, G16A, L19Q, K20I, M36I, K45R, K55R, L63P, C67G, A71V, I72L, I85VD
 RenG16031RenG16031KT747059PINAL90MV11IL10I, I15V, L19Q, K20T, E35G, M36I, P39S, R41K, I62V, L63P, H69Y, A71V, I72L, T74SD
 RenG17129RenG17129KT748157PINAM46I, I54V, V82A, L90ML33F, K43T, F53L, G73SL10V, L19I, K20R, E35D, M36I, R41K, K55R, R57RK, I62V, L63P, C67L, H69Q, A71V, I72LD
 RenG15645RenG15645KT746673PINAM46I, I54V, I84V, L90ML10F, F53L, T74PI13V, K20R, E35D, M36I, R41K, K55H, R57K, L63P, H69R, A71V, L89I, T91S, Q92KD
 RenG17296RenG17296KT748324PINAV32I, M46I, I54V, L90ML33I, G73S, N83DL10I, I15IV, Q18E, K20R, E35N, M36I, R41K, R57K, Q61D, L63P, C67Y, G68E, H69Y, A71V, I72RD
 RenG15993RenG15993KT747021PINAM46L, I47V, L76V, V82TF53L, L89VL10V, I13V, I15V, Q18H, K20I, E34EK, E35EK, M36I, N37E, K55R, I62V, L63P, K70KT, A71V, V77ID
 RenG16880RenG16880KT747908PINAM46L, I54V, V82ML24I, F53LL10V, T12P, K20R, E35D, M36I, N37Q, R41K, L63P, A71V, V77I, I93LD
 RenG17066RenG17066KT748094PINAI54L, L90MG73SI15IV, K20T, E35D, M36I, R41K, K45KR, L63P, A71VD
 RenG15641RenG15641KT746669PINAM46I, I54L, L76V, I84VL10F, V11VII13V, I15V, L19LQ, K20I, E35NS, M36I, R41K, K55KR, R57RK, D60E, Q61N, I62V, L63P, I64IV, A71V, I72V, N83NH, T91SD
 RenG17301RenG17301KT748329PINAI50LV32A, L33F, Q58EL10V, I13V, L19I, K20T, E34N, E35D, M36I, L63P, I64IL, A71V, I72T, V77IL, I93LD
 RenG15928RenG15928KT746956PINAM46L, I54V, V82AL24I, Q58E, G73SL10I, T12N, I15V, L19P, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, L63P, A71V, I72LD
 RenG16020RenG16020KT747048PINAM46I, I54A, V82AL24I, K43TL10I, I15IV, K20R, E35D, M36I, N37H, R41K, I62V, L63E, I64V, A71V, I72V, V77I, I93LD
 RenG16023RenG16023KT747051PINAV32I, M46L, I47V, I50L, V82A, I84VL33F, Q58ET12N, I13V, I15V, K20R, E35D, M36I, N37E, Q61QH, L63T, I64V, A71V, I72V, G78GV, R87RI, L89MD
 RenG16876RenG16876KT747904PINAI50L, V82AL33FI13V, K20KT, E35D, M36I, R41K, L63A, A71V, T91SD
 RenG16182RenG16182KT747210PINAM46I, I54V, I84V, L90MV11I, G73SL10I, I13IV, I15V, K20KIM, E21Q, E35D, M36I, N37D, R57RK, D60DE, Q61N, L63P, H69HR, A71V, I72M, I85IV, I93LD
 RenG14914RenG14914KT745942PINAM46L, I54V, V82A, L90M L10V, I13V, G17E, Q18H, K20I, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63AT, E65D, A71V, I72IV, T74S, I93LD
 RenG15014RenG15014KT746042PINAM46I, I54A, V82AL33I, Q58E, N83DL10V, I13A, K14R, K20R, A22V, E35N, M36I, N37D, I62V, L63P, I64V, H69K, A71V, Q92KD
 RenG15415RenG15415KT746443PINAM46I, N88SQ58EL10V, I13IV, I15V, K20T, K55KR, L63P, A71V, V77I, T91SD
 RenG14584RenG14584KT745612PINAI54L, V82A, L90MV11I, L33F, K43T, F53L, G73SI13V, I15V, G16GCW, L19V, K20R, E21G, L24F, E35D, M36I, N37T, R41K, K55R, R57K, D60E, Q61H, I62V, L63P, A71V, I72FD
 RenG14846RenG14846KT745874PINAM46L, I54V, V82A, L90ML33FL10V, I15V, G16E, K20M, E35N, M36I, L38LF, R41K, K55R, R57K, Q61D, I62V, L63C, I64IL, E65ED, A71V, I72IT, T74S, T91A, I93LD
 RenG14898RenG14898KT745926PINAM46I, I54V, I84V, L90MV11I, G73SL10IM, T12P, K14*, I15V, L19P, K20I, E35D, M36I, N37D, D60DE, Q61N, L63P, H69HR, A71V, I72M, I85V, I93LD
 RenG13694RenG13694KT744722PINAV32I, I47V, G48V, I54V, V82A, L90ML33F, F53L, Q58E, L89VL10I, I13V, K14E, I15V, K20R, E34Q, E35D, M36I, N37D, R41K, K55R, V56I, R57K, D60E, I62V, L63P, A71V, I85V, Q92KD
 RenG13674RenG13674KT744702PINAV82A, L90ML33F, K43T, G73SL10V, I13V, I15V, L19I, K20T, E35D, M36I, R41K, L63P, A71V, T74S, V77I, I93LD
 RenG13686RenG13686KT744714PINAM46I, I47V, I54V, V82F, L90MQ58EL10V, I13V, K20I, E35D, M36I, R41K, I62V, L63P, I64V, A71V, I93LD
 RenG14154RenG14154KT745182PINAM46MIL, I54V, V82FL33LIL10V, I13IV, I15V, K20RT, E35DN, M36I, R41K, Y59YH, D60DE, I62V, L63PS, I64IL, A71V, I72T, T74AS, V77VI, I93LD
 RenG12426RenG12426KT743454PINAM46I, I54V, V82S, I84VK43T, L89VL10I, I15V, L19IV, K20R, M36I, I62IV, L63P, K70R, A71V, I72M, Q92KD
 RenG12015RenG12015KT743043PINAG48A, I54V, V82A, L90MG73SL10I, K14R, I15V, E35ED, R41K, L63P, I64IV, A71V, I85VD
 RenG12108RenG12108KT743136PINAM46L, I54V, L76V, V82AL33FL10V, K20KR, E35D, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, I64L, A71V, I93LD
 RenG13216RenG13216KT744244PINAI50L I13V, I15V, K20R, E35D, M36I, N37NT, R41K, K45R, I62V, L63P, A71VD
 RenG12729RenG12729KT743757PINAG48M, I54V, V82VA, L90ML33I, F53L, N83DL10V, T12I, I13A, A22V, E35H, M36I, N37NS, R41K, K43KQ, R57K, Q61N, I62V, L63P, H69Y, A71V, I72T, L89I, I93LD
 RenG13053RenG13053KT744081PINAV32I, M46L, G48GV, I50IL, V82A, L90ML33F, G73GS, L89VL10I, I13V, L19I, L24LF, E34EQ, E35ED, M36I, N37S, R41K, K55HQ, I62IV, L63A, I64L, A71VD
 RenG13314RenG13314KT744342PINAV82A, L90MN88DL10I, I13IV, G16A, K20R, E35D, M36I, N37ND, R41K, K43KR, R57K, Q61N, L63P, I64IV, K70KN, A71V, I72V, I93IMD
 RenG12872RenG12872KT743900PINAM46L, I54V, I84V, L90ML10F, V11VI, Q58E, G73SI15V, K20KM, M36I, N37E, R41K, K55R, R57RK, I62V, L63P, A71V, N83SD
 RenG12091RenG12091KT743119PINAM46I, I54V, V82A, L90MG73S, L89VL10V, I13V, K20T, L33L_L, M36I, R41K, K55R, I62IV, L63P, I64IL, A71V, I93L, N98ID
 RenG10992RenG10992KT742020PINA  Q7E, T12TP, K14R, E35D, M36I, N37D, R41K, L63P, I64L, A71V, I72IV, V77I, I93LD
 RenG11212RenG11212KT742240PINAD30N, I54LL10F, L33I, N83D, N88DI13V, K14R, A22V, E34N, M36I, N37D, L63P, H69K, A71V, I72V, T74SD
 RenG11287RenG11287KT742315PINAM46I, I54V, V82A, L90ML10F, K43T, G73TQ7DE, P9PL, I13M, I15V, K20I, E21EQ, E35N, M36I, R41RK, K55R, R57RK, I62IV, L63P, I64V, A71V, I72T, I85V, I93LD
 RenG11503RenG11503KT742531PINAM46I, I50V, I54V, V82AK43T, F53LL10V, I15V, K20T, E35D, M36I, N37D, R41K, L63LP, I64V, A71V, V77ID
 RenG11491RenG11491KT742519PINAM46L, I54V, V82A, L90MG73TL10I, I15V, G16E, K20R, E35D, M36I, R41K, K55R, R57K, Q61D, A71V, I72R, I93LD
 RenG11079RenG11079KT742107PINAM46L, V82AL24IL10I, I15V, L19V, K20KR, E35D, M36I, P39S, R41K, K55R, R57K, I62V, L63P, A71V, L89LM, I93LD
 RenG11099RenG11099KT742127PINAM46L, I54V, L76V, V82A, L90M L10V, I15V, K20R, M36I, N37D, R41K, I62V, L63P, I64V, H69R, A71V, I72V, I85V, I93LD
 RenG10591RenG10591KT741619PINAL90ML23I, F53LL10I, T12K, I13L, I15V, L19Q, K20T, E35D, M36I, N37NADT, R41K, K55R, R57K, I62V, L63P, I66IV, A71V, T74S, V75ID
 RenG11575RenG11575KT742603PINAM46L, G48A, I50L, V82A L10I, T12K, I15V, G16A, K20R, L24R, E35D, M36I, R41K, K55R, R57K, Q61N, L63P, E65D, H69Y, A71V, I72T, I93LD
 RenG11171RenG11171KT742199PINAI54V, L90M L10V, I15V, K20T, E35G, M36I, N37D, R41K, I62V, L63P, A71V, T74S, I85IV, I93LD
 RenG10904RenG10904KT741932PINAI54L L10V, I15V, G16E, K20A, E35N, M36I, P39S, R41K, R57K, D60E, I62V, L63T, I64L, E65ED, A71V, I72T, I93LD
 RenG10437RenG10437KT741465PINAI54V, V82A, L90M L10V, T12E, I15V, L19I, K20T, E35N, M36I, R41K, I62V, L63P, I64M, A71V, T74S, I93LD
 RenG10617RenG10617KT741645PINAV32I, M46I, I47V, I54V, V82A, L90MV11I, L33F, G73S, L89VL10V, I13V, I15V, L19P, K20R, M36I, N37D, K55R, R57K, I62V, L63P, I64L, A71V, I72VD
 RenG11215RenG11215KT742243PINAM46L, I54V, V82F, I84V, L90ML33F, Q58EL10IV, I15V, K20KR, E35N, M36IV, N37E, R41K, R57RK, I62V, I64V, A71V, I93LD