<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation A71T
Rx PI-naive
IncludeMixtures No
References 36
Patients 49
Isolates 50
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Eshleman (2001)SE33SE33AF388065None  I50IF, L76II13V, M36I, R41K, L63P, I64V, A71T, I72IV, V77ID
Cuevas (2002)CU65CU65AF425446None   E35D, M36I, N37D, R41K, K43R, L63P, I64L, H69Q, K70R, A71T, I72VD
 CU30CU30AF425411None   R41K, K43R, R57K, I62V, L63P, H69Q, A71T, V77I, I93LD
Hierholzer (2002)SU488SU488AY102484None   I13V, I15V, G16E, N37T, P39S, R41K, D60E, L63P, A71T, I93LD
 SU053SU053AY102493None   G16E, M36I, P39T, R41K, I62V, L63H, A71TD
Jorgensen (2003)JLB_Pat36HIM419462AJ419462None   T12K, R41K, A71TD
Vidal (2006)NV_KS01702.KS017AM041044None   L10V, I13V, G16A, M36I, R41K, I62V, H69K, A71TD
Church (2007)033-109176I033EF611998None   I13IV, M36I, R41K, L63LP, I64V, A71T, V77ID
Vidal (2007)U192902BU.U1929AM260231None   I13V, R41K, L63P, H69K, A71T, V77ID
Delgado (2008)GH_056GH_056EU177926None   T12A, R41K, Q61N, L63A, A71T, I72IM, V77ID
Nyombi (2008)TMS201TMS201EU251838None   L10I, I13V, L19Q, M36MI, R41K, I64V, K70R, A71TD
 TMS220TMS220EU251853None   L10V, I13V, E35D, P39Q, R41K, D60E, L63P, I64V, H69K, A71T, V77ID
Somi (2008)BG-05-896BG-05-896JQ616953None   M36I, P39T, R41K, I62V, L63P, I64L, A71TD
Eshleman (2009)H20818W208-101503FJ389107None   I13V, K14R, K20R, M36I, N37D, R41K, A71TD
Djoko (2010)662CD2996FR666662None   K14KR, R41K, L63P, H69Q, A71T, V77VID
Soares (2010)CM04_050CM04_050GU366145None   L19I, E35D, M36I, R41K, R57K, I62V, L63S, A71T, I72V, V77ID
Towler (2010)8418316-GHM037887None   L10V, G17E, R41K, L63P, A71T, I72V, F99LD
  505503-GHM037899None   L10V, G17DE, R41K, L63P, A71T, I72VD
 378415-M378415-MHM037864None   E35D, R41K, L63P, I64L, A71T, V77ID
Hamers (2011)CP076303053CP076303053HQ995235None   I13V, R41K, L63P, I64L, A71TD
De Gascun (2012)IRL32980IRL32980JN622307None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
 IRL32981IRL32981JN622308None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
Delwart (2012)479-2547-7479-2547-7JN215097None   I15V, E35D, M36I, N37D, R41K, K43R, Q61E, L63P, H69Q, A71T, I72V, I93LD
Karlsson (2012)SE_259SE_259JQ698846None   E35D, N37D, R41K, K43R, L63P, A71T, Q92RD
Machado (2012)CUPL0941CUPL0941HQ655374None   T12P, L19I, K20R, E35D, M36I, R41K, L63P, H69Q, K70E, A71T, I93LD
 CUPL1043CUPL1043JN000015None   T12K, I13V, L19I, E35D, R41K, L63P, H69Q, A71TD
 CUPL1080CUPL1080JN000052None   E35D, M36I, R41K, K43R, I62V, L63P, H69Q, K70Q, A71T, I93LD
 CUPL1084CUPL1084JN000056None   I13V, L19I, R41K, L63P, H69Q, A71TD
 CUPL1118CUPL1118JX194197None   I13V, L19I, E35D, R41K, L63P, H69Q, A71TD
Nazziwa (2012)50691025069102JX499003None   I3L, L10I, I13V, R41K, K45R, L63AD, A71T, I72E, V77ID
Serrano (2012)20106934362010693436JQ616878None   L10I, I13V, I15V, K20I, E35D, M36I, R41K, Q61H, K70R, A71T, I72ED
 20106934532010693453JQ616908None   L10I, I13V, I15V, K20I, E35D, M36I, R41K, H69L, K70R, A71T, I72ED
Bila (2013)MZAng38HIV-1KF927401None   T12A, L19I, R41K, I62V, L63P, I64L, A71T, I72E, V75I, V77ID
Frentz (2013)EHR-25464EHR-25464JX299982None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
 EHR-92753EHR-92753JX301085None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
Hassan (2013)RS11000306RS11000306JQ698391None   I13V, R57K, L63P, A71T, I72V, V77ID
Lee (2014)MBA1360MBA1360KJ907046None   I13V, Q18QP, L23LP, R41K, L63P, A71T, I72V, V77ID
 MBA1407MBA1407KJ907092None   L10I, I13V, L19I, K20KR, M36I, R41K, R57K, I62V, I64V, A71T, I72MD
Ross (2014)12151215KF263130None   E35ED, N37NS, R41K, R57K, D60E, I62V, L63P, I64L, A71TD
Velasco-de-Castro (2014)07BRRJRS11107BRRJRS111KF922198None   I15V, Q18A, E35D, R41K, R57K, D60E, I62V, L63P, H69Q, A71T, V77I, I93LD
Wallis (2014)4123041230KM458598None   R41K, K43R, L63S, H69K, A71T, V77ID
Budambula (2015)MK107MK107KP792101None  L33II13V, R41K, H69K, A71T, I93MD
Dauwe (2015)i5_06004i5_06004KT863881None   L10V, M36MI, R41K, I62IV, L63PS, H69Q, A71T, I72V, V77I, I85IVD
Kouri (2015)AIDS-RP28AIDS-RP28KP688103None   I13V, L19I, E35D, N37S, R41K, L63P, H69Q, A71TD
 AIDS-RP2AIDS-RP2KP688094None   I15V, E35D, M36I, R41K, K43R, I62IV, L63PS, H69K, K70Q, A71T, I93LD
Meini (2015)112327112327KM438301None   T12S, E35D, N37S, R41K, L63P, A71T, V77ID
Onsongo (2016)3939KM376169None   R41K, K45R, R57K, L63A, I64V, A71T, I72V, V77I, I93LD
Otecko (2016)412952412952KX306465None   L19I, E35D, P39Q, R41K, L63P, A71T, V77ID
Reynolds (2016)H105957R16H105957R16KX944679None   I13V, R41K, L63S, H69K, A71TD
Steegen (2016)GFECA005GFECA005KT893249None   I13V, E35D, N37H, R41K, R57K, L63P, A71T, I72IEKV, V77ID