<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation A71T
Rx PI-naive
IncludeMixtures No
References 30
Patients 46
Isolates 47
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Eshleman (2001)SE33SE33AF388065None  I50IF, L76II13V, M36I, R41K, L63P, I64V, A71T, I72IV, V77ID
Cuevas (2002)CU65CU65AF425446None   E35D, M36I, N37D, R41K, K43R, L63P, I64L, H69Q, K70R, A71T, I72VD
 CU30CU30AF425411None   R41K, K43R, R57K, I62V, L63P, H69Q, A71T, V77I, I93LD
Hierholzer (2002)SU488SU488AY102484None   I13V, I15V, G16E, N37T, P39S, R41K, D60E, L63P, A71T, I93LD
 SU053SU053AY102493None   G16E, M36I, P39T, R41K, I62V, L63H, A71TD
Jorgensen (2003)JLB_Pat36HIM419462AJ419462None   T12K, R41K, A71TD
Eshleman (2004)ESH_Pat82ESH783AY435367None   L10I, I13V, R41K, L63V, H69Q, A71T, V77VID
Niama (2006)CHU31CHU31FM164913None   L10I, R41K, I62V, L63C, H69Q, A71T, V77ID
Church (2007)033-109176I033EF611998None   I13IV, M36I, R41K, L63LP, I64V, A71T, V77ID
 783-140837P783EF612144None   L10I, I13V, R41K, L63IV, H69Q, A71T, V77VID
Vidal (2007)U192902BU.U1929AM260231None   I13V, R41K, L63P, H69K, A71T, V77ID
Delgado (2008)GH_056GH_056EU177926None   T12A, R41K, Q61N, L63A, A71T, I72IM, V77ID
Holguin (2008)SP27-289350SP27-289350EU255400None   L10V, I13IV, E35D, N37H, R41K, I62V, L63P, A71TD
Nyombi (2008)TBK093TBK093EU251775None   T12S, I13V, I15V, L19I, E35D, R41K, L63T, H69KQ, A71T, V82I, I93LD
 TMS201TMS201EU251838None   L10I, I13V, L19Q, M36MI, R41K, I64V, K70R, A71TD
 TMS220TMS220EU251853None   L10V, I13V, E35D, P39Q, R41K, D60E, L63P, I64V, H69K, A71T, V77ID
Somi (2008)BG-05-896BG-05-896JQ616953None   M36I, P39T, R41K, I62V, L63P, I64L, A71TD
Eshleman (2009)H20818W208-101503FJ389107None   I13V, K14R, K20R, M36I, N37D, R41K, A71TD
Djoko (2010)662CD2996FR666662None   K14KR, R41K, L63P, H69Q, A71T, V77VID
Soares (2010)CM04_050CM04_050GU366145None   L19I, E35D, M36I, R41K, R57K, I62V, L63S, A71T, I72V, V77ID
Towler (2010)8418316-GHM037887None   L10V, G17E, R41K, L63P, A71T, I72V, F99LD
  505503-GHM037899None   L10V, G17DE, R41K, L63P, A71T, I72VD
 378415-M378415-MHM037864None   E35D, R41K, L63P, I64L, A71T, V77ID
Hamers (2011)CP076303053CP076303053HQ995235None   I13V, R41K, L63P, I64L, A71TD
De Gascun (2012)IRL32980IRL32980JN622307None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
 IRL32981IRL32981JN622308None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
Delwart (2012)479-2547-7479-2547-7JN215097None   I15V, E35D, M36I, N37D, R41K, K43R, Q61E, L63P, H69Q, A71T, I72V, I93LD
Karlsson (2012)SE_259SE_259JQ698846None   E35D, N37D, R41K, K43R, L63P, A71T, Q92RD
Machado (2012)CUPL0941CUPL0941HQ655374None   T12P, L19I, K20R, E35D, M36I, R41K, L63P, H69Q, K70E, A71T, I93LD
 CUPL1080CUPL1080JN000052None   E35D, M36I, R41K, K43R, I62V, L63P, H69Q, K70Q, A71T, I93LD
 CUPL1084CUPL1084JN000056None   I13V, L19I, R41K, L63P, H69Q, A71TD
Nazziwa (2012)50691025069102JX499003None   I3L, L10I, I13V, R41K, K45R, L63AD, A71T, I72E, V77ID
Serrano (2012)20106934362010693436JQ616878None   L10I, I13V, I15V, K20I, E35D, M36I, R41K, Q61H, K70R, A71T, I72ED
 20106934532010693453JQ616908None   L10I, I13V, I15V, K20I, E35D, M36I, R41K, H69L, K70R, A71T, I72ED
Bila (2013)MZAng38HIV-1KF927401None   T12A, L19I, R41K, I62V, L63P, I64L, A71T, I72E, V75I, V77ID
Frentz (2013)EHR-25464EHR-25464JX299982None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
 EHR-92753EHR-92753JX301085None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
Hassan (2013)RS11000306RS11000306JQ698391None   I13V, R57K, L63P, A71T, I72V, V77ID
Kiertiburanakul (2013)R51TS021R51TS021KF059666None  L33FT12V, I13IV, E35D, N37D, R41RK, R57K, I62V, L63P, I64IL, A71TD
Chikata (2014)KI-946KI-946AB874232None   T12A, E35D, R41K, I62V, L63A, A71T, I72TD
 KI-818KI-818AB874134None   T12A, E35D, R41K, I62V, L63A, A71T, I72TD
 KI-825KI-825AB874149None   T12A, E35D, R41K, I62V, L63A, A71T, I72TD
Lee (2014)MBA1360MBA1360KJ907046None   I13V, Q18QP, L23LP, R41K, L63P, A71T, I72V, V77ID
 MBA1407MBA1407KJ907092None   L10I, I13V, L19I, K20KR, M36I, R41K, R57K, I62V, I64V, A71T, I72MD
Meixenberger (2014)12-0328312-03283KJ771816None   Q18M, E35D, M36I, R41K, I62IV, L63P, A71T, I72IV, V77I, I93LD
 09-0341209-03412KJ771112None   Q18IM, E35D, M36I, R41K, L63P, A71T, V77VI, I93LD
 11-0396011-03960KJ771630None   Q18M, E35D, M36I, R41K, L63P, A71T, V77I, I93LD