<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L63V
Rx PI-naive
IncludeMixtures No
References 17
Patients 23
Isolates 23
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Eshleman (2004)ESH_Pat82ESH783AY435367None   L10I, I13V, R41K, L63V, H69Q, A71T, V77VID
Church (2008)389271-L389271-LEU380745None  L33II13V, M36T, R41K, D60E, L63V, I64V, E65DD
Ndembi (2008)IAEM026IAEM026EU306760None   I13V, I15V, Q18E, R41K, Y59H, L63V, I64VD
Eshleman (2009)F03996W108-101570FJ389123None   I13V, I15V, M36I, R41K, L63V, I64V, E65DD
Ndembi (2010)13765D_P113765GQ409558None   L10V, M36I, L63V, I64V, H69KD
Hamers (2011)CP076303180CP076303180HQ994196None   K14G, I15V, K20R, M36I, R41K, I62V, L63V, E65D, H69K, I72V, T74S, L89MD
 CP076300815CP076300815HQ994947None   I13V, M36I, R41K, L63V, I64VD
 CP076301867CP076301867HQ995002None  Q58EI13V, K20R, M36I, N37D, R41K, R57K, L63V, I64VD
 CP076303012CP076303012HQ995077None   L10I, I13V, L19M, M36I, R41K, L63V, I64V, E65DD
 CP076301840CP076301840HQ995167None   L10I, I13V, L19M, M36I, R41K, L63V, I64V, E65DD
 CP076301995CP076301995HQ995180None   L10V, L19I, M36I, R41K, D60E, I62V, L63V, I64VD
Musyoki (2012)DGM.2DGM.2JN176287None   T12S, I15V, L19I, E35D, M36I, P39T, R41K, L63V, H69K, L89M, I93LD
Ndase (2012)5004148250041482KC900789None   I13V, G16E, M36L, N37K, R41K, L63VD
Reynolds (2012)B0708B0708-1JN652172None   L10I, I13V, G16E, M36I, R41K, L63VD
Ssemwanga (2012)2910HR2910HRJF800222None   K20R, M36I, R41K, L63V, E65D, I72VD
Alencar (2013)RJ2-0026RJ2-0026JQ238085None   I15V, L19I, E35D, M36I, R41K, L63V, I64L, H69KD
Bila (2013)MZNAC60HIV-1KF927425None   G16E, M36I, R41K, L63V, H69K, L89M, I93LD
 MZ10-262HIV-1KF927351None   L19I, M36I, R41K, K43KR, L63V, H69K, T74S, L89M, I93LD
Sigaloff (2013)JCR073_0JCR073_0JX181993None  L33II13V, M36T, R41K, D60E, I62V, L63V, I64V, E65D, K70RD
Lee (2014)MBA1204MBA1204KJ906901None   I13IV, L33V, N37S, R41K, L63V, I64V, E65DD
Novitsky (2015)mpp_022mpp_022KR860812None   T12S, I15V, L19I, E35D, M36I, R41K, L63V, H69K, T74S, L89M, I93LD
Onsongo (2016)11KM463084None   R41K, R57K, L63V, I64V, E65D, K70R, V77ID
Onywera (2017)09522010952201KX791033None   T12S, I15V, L19I, M36I, R41K, R57K, L63V, H69K, T74A, L89MD