<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L63T
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 7
Isolates 8
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Jorgensen (2000)LBJ13LBJ13D_0AJ404412IDV   T4I, L5R, W6G, R8R*G, L10I, I13V, L23P, M36I, R41K, D60E, I62V, L63T, I64V, I72VD
de Sa Filho (2003)BREPM093BREPM093AY182806IDV   K20R, D25DHNY, M36I, R41K, L63T, E65D, I72T, L89M, Q92QHD
Non-B Workgroup (2005)TK2025TK2025 IDV, RTV, SQV151  L10I, V11G, I13V, E21EG, T31TS, M36I, R41K, D60E, I62V, L63T, I64V, I72VD
  TK2025a IDV, RTV, SQV, LPV347  L10I, I13V, M36I, R41K, D60E, L63T, I64V, I72VD
Jones (2012)145636145636JN669661PINA  L10I, I13V, E35D, M36I, R41K, Q61D, L63T, K70F, I72TD
Alcantara (2013)BRGO4151BRGO4151JN662432LPV   L10V, I13V, G16E, M36I, R41K, L63TD
Van Zyl (2013)364111.ZA.GT1597KC423388LPV   L10V, G16E, M36I, N37Q, R41K, D60E, L63T, H69K, I72V, I93LD
Diaz (2015)RenG16432RenG16432KT747460PINAI50L, N88SQ58EL10V, G16E, K20R, E35D, M36I, N37T, L63T, E65ED, H69K, A71V, I72T, L89M, I93LD