<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L63T
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 42
Isolates 42
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)TK2025TK2025a IDV, RTV, SQV, LPV347  L10I, I13V, M36I, R41K, D60E, L63T, I64V, I72VD
Riddler (2008)RG27158RG27158w108 LPV103  K14R, I15V, M36I, R41K, L63T, E65D, I72TD
Rangel (2010)HIV244bHIV244bGU807502PINA  L10I, R41K, L63T, I93LD
Aulicino (2011)ARN397RLRARN397RLRFJ525859PINAM46L, I54L, V82T, I84VL24I, L33F, K43TE35D, M36I, N37E, R41K, R57K, D60N, Q61N, L63T, I64L, A71I, I72T, L89M, I93LD
 476-O345RMS476-O345RMSHQ158190PINA  G16E, E35D, M36I, R41K, R57K, Q61N, I62T, L63T, A71V, I72M, I93LD
Jones (2012)145636145636JN669661PINA  L10I, I13V, E35D, M36I, R41K, Q61D, L63T, K70F, I72TD
 157949157949JN669903PINAM46MI, I54V, L76LV, V82F, L90ML33FL10I, I13V, K20IT, E35D, M36I, R41K, D60E, Q61N, I62V, L63T, I64L, C67D, A71AV, I72IT, I93LD
 162542162542JN670041PINA  L10I, I15V, K20R, M36I, R41K, K43R, R57K, Q61N, L63T, C67S, I93LD
 163239163239JN670057PINAM46I, V82T, I84VL10FT12K, I13V, G16E, L19P, K20R, M36I, L63T, I64V, E65D, I72T, T74SD
 163678163678JN670068PINAL90LM L10V, I13V, I15V, K20T, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, I64L, I72T, T74S, I93LD
 177131177131JN670427PINA  L10V, T12A, I13V, K14R, G16GE, E35D, M36I, R41K, Q61D, L63T, I64V, I72TD
 179481179481JN670511PINA  L10I, Q18E, E35D, M36I, R41K, Q61N, L63T, I72T, I93LD
 183366183366JN670645PINA  L10I, I13V, I15V, M36I, N37D, L63T, I64L, I93LD
 185340185340JN670703PINA  I15V, E35D, M36I, R41K, K43R, R57K, L63TD
 185997185997JN670710PINAL90M L10I, I13V, K20T, E35D, M36I, R41K, R57RK, D60E, Q61N, I62V, L63T, I64L, C67D, I72T, V82VI, I93LD
 195598195598JN670988PINAM46I, V82A L10V, E35D, M36I, R41K, R57K, Q61D, L63T, E65D, I72T, V77ID
 207305207305JN671429PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, K20T, E35D, M36I, R41K, D60E, Q61N, I62V, L63T, I64L, C67D, A71V, I72T, I93LD
Kouri (2012)CU749-09CU749-09JQ585263PINAM46L, I84VN83DL10I, I15V, G16E, K20R, M36I, R41K, D60E, I62IV, L63T, V82I, L89LFD
 CU2073-09CU2073-09JQ585339PINAM46L, I54V, V82AF53LL10I, I13V, G16E, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, Q61H, L63T, E65D, I72T, T74A, L89MD
 CU772-10CU772-10JQ585416PINAM46L, I54AV, V82AL33F, T74AP, N83NDL10I, I13V, I15IV, G16E, K20R, E35D, M36I, N37D, R41K, R57K, L63T, E65D, L89MD
Diaz (2015)RenG16518RenG16518KT747546PINAM46I, I47V, I54V, V82A, L90MV11I, K43T, F53L, G73C, T74P, L89VL10V, T12K, I13A, I15V, L19I, K20I, E34Q, E35D, M36I, N37E, K55R, I62V, L63T, I72VD
 RenG17021RenG17021KT748049PINAV32I, I47V, I50V, I54L, V82ML33F, K43T, T74PL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37S, R57K, Q61N, L63T, E65D, I72V, L89FD
 RenG15900RenG15900KT746928PINA  L10I, T12S, I15V, K20R, E35D, M36I, R41K, L63TD
 RenG16023RenG16023KT747051PINAV32I, M46L, I47V, I50L, V82A, I84VL33F, Q58ET12N, I13V, I15V, K20R, E35D, M36I, N37E, Q61QH, L63T, I64V, A71V, I72V, G78GV, R87RI, L89MD
 RenG16242RenG16242KT747270PINA  L10V, T12P, K14R, I15V, G16E, L19LF, K20R, E35D, M36I, N37D, R41K, L63T, I72T, I93LD
 RenG16026RenG16026KT747054PINA  R8H, I13V, G17E, E35D, M36I, N37D, R41K, R57RK, Q61DGNS, L63T, I64IV, E65DD
 RenG13657RenG13657KT744685PINA  W6R, Q7R, L10*, V11C, I15V, K20R, E35D, M36I, R41K, L63T, I72TD
 RenG14385RenG14385KT745413PINAM46L, G48Q, I54V, L76V, I84VL24IL10I, I15V, G16E, K20R, E35D, M36I, R41K, R57RK, Q61N, L63T, I64L, I72T, V82VI, L89M, Q92QKD
 RenG15039RenG15039KT746067PINAM46I, G48S, I54S, V82ML24I, K43TL10V, L19IV, K20R, E35D, M36I, R41K, F53Y, K55Q, R57K, D60DN, Q61DN, I62V, L63T, I64V, E65D, I72T, T74AD
 RenG14088RenG14088KT745116PINA  I13V, E35D, M36I, R41K, Q61N, L63T, E65D, I72T, L89MD
 RenG13605RenG13605KT744633PINAI50L, V82A, L90ML33F, F53L, Q58E, T74PSL10V, T12E, I13V, K14R, I15V, G16E, K20T, E35D, M36I, P39T, R41K, I62V, L63T, I64V, H69K, A71L, V77VL, I93LD
 RenG15072RenG15072KT746100PINAM46L, I54V, L76V, V82A, L90ML33F, Q58EL10V, I13V, K14R, G16E, K20R, E35D, M36I, N37E, P39S, R41RK, K55R, R57K, D60DE, Q61N, I62V, L63T, I64V, K70KT, V77ID
 RenG14611RenG14611KT745639PINA  L10I, I15IV, G16E, E35D, M36I, R41K, I62V, L63T, E65D, I72IMD
 RenG13801RenG13801KT744829PINA  I15V, M36I, R41K, I62IV, L63TD
 RenG12432RenG12432KT743460PINAM46L, I54V, I84VL24I, G48EL10I, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, I64L, I72T, V82VI, L89M, Q92KD
 RenG13073RenG13073KT744101PINAD30N, I50L, V82AL33F, N88DL10I, I13V, K20R, E35D, M36I, N37E, K45I, I62IV, L63T, I64V, A71AITV, T74S, I93LD
 RenG11579RenG11579KT742607PINA  I15V, E35D, M36I, R41K, L63T, I72TD
 RenG10085RenG10085KT741113PINA  I15V, K20R, E35D, M36I, R41K, L63T, I72TD
 RenG11291RenG11291KT742319PINA V11VIL10V, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63T, I72ITD
 RenG10236RenG10236KT741264PINA  L10V, I13V, I15V, G16E, E35D, M36I, R41K, R57K, L63T, E65D, I72V, L89MD
 RenG10904RenG10904KT741932PINAI54L L10V, I15V, G16E, K20A, E35N, M36I, P39S, R41K, R57K, D60E, I62V, L63T, I64L, E65ED, A71V, I72T, I93LD
 RenG10170RenG10170KT741198PINAM46L, I54V, V82A L10I, I13V, G16E, K20R, M36I, N37ND, R41K, Q61N, L63T, I64IL, E65ED, L89MD