<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L63S
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 20
Isolates 20
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)TK3003TK3003 SQV, NFV247I54V, L90M K20T, E35D, M36I, N37DE, R41K, D60E, I62V, L63S, I64V, V77VI, V82ID
Baxter (2006)48-33733373-30620DQ878231PINAM46L, G48V, I54V, V82A L10V, I15V, L19I, R41K, I62V, L63S, I64L, V77ID
Aulicino (2011)322-N783QMM322-N783QMMHQ158159PINA  T12I, E35D, M36I, R41K, Q61N, L63SD
 4671-O214HCH4671-O214HCHHQ158192PINA  I15V, K20R, M36I, R41K, R57K, Q61N, L63S, I64LD
El Annaz (2012)14881488.PRJN185238IDV52  L19Q, K20M, E35D, M36I, R41K, L63S, I64VD
Jones (2012)127025127025JN669433PINAL90M L10I, E35D, M36I, R41K, Q61N, L63S, I64L, I93LD
 171988171988JN670278PINA  L10I, E35D, M36I, R41K, R57K, D60E, Q61N, L63S, I72T, I93LD
 188898188898JN670762PINAD30NN88DL10V, I13V, K14R, G16E, K20M, E35G, M36I, R41K, R57K, Q61N, L63SD
 201210201210JN671216PINAI54V, V82T, I84VL33F, F53LL10I, I15V, K20R, E35D, M36I, N37D, R41K, Q61N, L63S, I64L, A71V, I72T, T74S, I85V, L89M, I93LD
 203943203943JN671324PINAV32I, M46I, I54V, V82AL24I, L33F, K43T, F53LL10I, I13V, G16E, K20R, E35D, M36I, N37D, P39PS, R57K, Q61N, L63S, E65D, K70Q, A71V, T74S, V77I, L89TD
Reynolds (2012)B0715B0715-2JN652205LPV  L33II13V, M36T, P39S, R41K, L63S, I64VD
Inzaule (2013)317317JQ914083NFV   I13V, I15V, M36I, R41K, I62V, L63S, I64V, E65DD
Diaz (2015)RenG16090RenG16090KT747118PINA  L10I, T12I, I13V, G16E, K20KR, M36I, R41K, R57K, Q61N, L63S, E65D, I72TD
 RenG15685RenG15685KT746713PINA  T12TI, E35D, M36I, R41K, K45R, R57K, Q61D, L63S, I72VD
 RenG16155RenG16155KT747183PINA  I15V, E35D, M36I, R41K, R57K, Q61N, L63S, V77I, I93LD
 RenG15468RenG15468KT746496PINA  Q7E, L10I, K14R, E35D, M36I, R41K, L63S, I64V, I72V, V77I, I93LD
 RenG13532RenG13532KT744560PINAD30N, M46L, I54IV, V82A, L90ML33F, F53L, N88DL10V, T12Q, I13V, I15V, G16GE, K20R, E35D, M36I, R41K, K55KN, Q61N, L63S, I93ILD
 RenG12639RenG12639KT743667PINAV32I, M46I, I47V, I54M, V82A, L90ML33F, F53L, T74TPL10I, I13V, G16GE, K20R, E34A, E35D, M36I, R41K, K45KR, K55KR, R57K, Q61N, L63S, C67E, I72V, V77VID
 RenG12340RenG12340KT743368PINAM46L, I50L, V82VA, N88SL33FL10V, I13V, I15IV, G16E, K20R, E35D, M36I, N37S, P39P*QS, R41K, K45R, R57K, Q61N, L63S, I64IV, I72TD
 RenG11553RenG11553KT742581PINA  M36I, L63S, H69K, I93LD