<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L63R
Rx PI-naive
IncludeMixtures No
References 5
Patients 6
Isolates 6
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Ndembi (2008)CMYD-304CMYD-3DQ990378None   E35D, M36I, R41K, L63R, K70E, R87KD
Nyombi (2008)TBK022TBK022EU251728None   L10I, I13V, M36I, R41K, L63R, I64V, C67G, K70E, I72VD
Mosha (2010)S2polS2polJQ071451None   I13V, I15V, M36I, R41K, L63R, I64V, K70ED
Hamers (2011)CP076301836CP076301836HQ994987None   T12A, I13V, G16E, R41K, R57K, L63R, I64VD
 CP076302051CP076302051HQ995203None   L10V, I13V, G16E, E35D, R41K, R57K, L63R, I64V, E65D, I72MD
Hassan (2013)RS11000282RS11000282JQ698372None   I13V, L33V, P39T, R41K, L63R, I64V, K70I, I72TD