<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L63Q
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 10
Isolates 10
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)UK062dUK062d NFV L90M L10V, I13V, L19I, K20T, E35D, M36I, R41K, I62V, L63Q, I64V, H69Y, T74S, Q92KD
Weber (2005)F75698F75698AY677379NFV39  I13V, R41K, L63Q, I64VD
 F55140F55140AY677472RTV, NFV197M46I, L90MQ58QEI13V, R41K, I62IV, L63Q, I64V, T74K, V77ID
Baxter (2006)12-30773077-30403DQ877151PINAD30NL10F, N88DI13V, K14R, E35D, M36I, R41K, I62IV, L63Q, I64VD
 48-80168016-30826DQ879061PINAM46L, I54LL10F, Q58EI13V, K20T, E35ED, M36I, N37ND, R41K, L63Q, I64VD
Dau (2010)07059A07059AGU581816PINAM46MI, I54V, V82A, L90LM L10I, I13V, I15V, K20V, M36I, R41K, I62V, L63Q, I64V, E65D, I72V, T74SD
Mollan (2012)MK180MK180w68 RTV, ATV19 Q58EL19V, K20R, E35D, M36I, R41K, R57K, D60E, Q61E, L63Q, C67E, H69K, L89MD
Van Zyl (2013)O17992567KC423747LPV26  L10I, I13V, G16E, M36I, R41K, L63Q, I64V, E65D, H69CD
Diaz (2015)RenG11632RenG11632KT742660PINAG48V, I54S, V82A, L90MQ58EL10I, I13V, L19T, K20I, L33L*, E34Q, E35D, M36I, N37D, D60E, I62V, L63Q, I64V, T74SD
Neogi (2016)61613.ZA.EC689KT592845LPV   I13IV, K14KR, N37S, R41K, R57K, L63Q, I64V, H69HY, V77ID