<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L63H
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 6
Isolates 6
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG7272_w15 NFV15  E35D, M36MI, R41K, R57K, I62V, L63H, I66IM, I93LD
Non-B Workgroup (2005)TK4014TK4014 SQV, RTV, NFV98  T12TP, I13V, I15IV, K20R, M36MI, R41K, L63H, I64V, I72IV, V77ID
von Wyl (2007)2410516511EF449876RTV, PINA  L10V, I13V, E35D, M36I, R41K, I62V, L63H, I64VD
Aulicino (2011)ARL411LCOARL411LCOFJ525808PINAD30NN88DL10Y, I13V, I15V, K20T, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63H, I72V, V75ID
Jones (2012)177852177852JN670462PINA  I13IV, I15V, K20R, M36I, N37E, R57K, Q61N, L63H, I64ILMD
 202646202646JN671284PINAI54L, L90ML33FL10V, I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, L63H, T74S, Q92QKD