<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L63C
Rx PI-naive
IncludeMixtures No
References 17
Patients 26
Isolates 27
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Eshleman (2001)SE474SE474AF388085None   E35D, M36I, R41K, L63C, I64V, I72IVD
Eshleman (2004)ESH_Pat131ESH512AY425351None   I13V, Q18H, M36I, N37NS, R41K, L63C, I64VD
Eshleman (2004) SE512_7dAY428689None   I13V, Q18H, M36I, N37NS, R41K, L63C, I64VD
Church (2007)512-128108h512EF612051None   I13V, Q18H, M36I, R41K, L63C, I64VD
 770-141405W770EF612139None   T12TA, I13V, K14KR, G16GE, L33V, M36I, R41K, D60DE, I62V, L63C, I64VD
Ndembi (2008)IAEM075IAEM075EU306792None   I15V, M36I, N37D, R41K, L63CD
Aghokeng (2009)CYM078CYM078GU191592None   L10V, G16E, E35D, N37S, R41K, R57K, L63CD
Towler (2010)335694-K335694-KHM037851None   T12TKN, I13V, L19I, M36I, R41K, L63C, I64VD
Hamers (2011)CP076301702CP076301702HQ993697None   P9PILT, L10LV, T12TS, I13V, K14KR, N37T, R41K, R57RK, D60DE, L63C, I64V, E65ED, K70KRD
 CP076300772CP076300772HQ995340None   L10V, I13V, G16E, M36I, R41K, L63CD
 CP076302897CP076302897HQ995469None   L10V, I13V, M36I, R41K, L63C, I64VD
Kasang (2011)1719317193HM572354None   L10V, T12I, I13V, G16E, M36I, N37T, P39S, R41K, L63C, I64VD
 3265032650HM572361None   T12TA, I13V, K14KR, K20R, M36I, N37D, R41K, L63C, I64V, H69YD
Sigaloff (2011)HIV102898HIV102898JN132316None   L10LI, I13V, G16GE, M36I, R41K, L63CD
Karlsson (2012)SE_290SE_290JQ698865None   R41K, L63C, I64IV, H69YD
Ndase (2012)5101849251018492KC900684None   I13V, K14KR, I15V, E35D, M36I, R41K, L63C, I64V, I72VD
Alencar (2013)MG2-0017MG2-0017JQ238023None   L10V, I13V, I15V, Q18M, M36I, N37D, R41K, L63CD
Frentz (2013)EHR-57646EHR-57646JX300501None   E35D, M36I, R41K, R57K, Q61N, L63C, H69QD
Lee (2014)MBA1061MBA1061KJ906762None   T12TP, I13IV, K14KR, G16E, E35ED, N37CS, R41K, D60E, L63C, I64V, E65D, I72IV, V77ID
 MBA1174MBA1174KJ906872None   I13V, K20R, M36I, R41K, L63C, I64V, K70RD
 MBA1328MBA1328KJ907014None   I13V, I15IV, K20KR, M36I, R41K, R57RK, Q61QH, I62IV, L63C, I64IV, E65EDD
 MBA1465MBA1465KJ907143None   I15V, E35D, M36I, R41K, R57K, L63C, I64V, E65D, H69HY, K70KRD
 MBA1478MBA1478KJ907156None   I13V, I15V, R41K, Q61N, L63C, I64V, E65D, I72IV, V77ID
 MBA1411MBA1411KJ907096None   T12AS, I15V, M36I, R41K, L63CD
 MBA1381MBA1381KJ907067None   I13V, M36I, R41K, L63C, I64V, V82ID
Pessoa (2015)10BR_MG017_1MG017_1KJ849792None   L10V, I13V, I15V, Q18M, M36I, N37D, R41K, L63CD
Dow (2017)1690116901KY747375None   R41K, Q61N, L63C, V75ID