<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L63C
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 14
Isolates 14
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)9881798817AY365582PINAD30N N37A, R41K, L63C, V77ID
 113575113575AY365879PINAD30N E35D, M36I, N37T, R41RK, L63C, I64V, A71V, I93LD
Baxter (2006)12-22582258-30721DQ876701PINAI54V, V82AL10FI13V, G16E, K20I, E35D, M36I, P39S, R41K, K45A, R57KT, I62V, L63C, I64VD
Aulicino (2011)3005-M993MNY3005-M993MNYHQ158168PINA  G17E, E35D, M36I, R41K, R57K, D60E, Q61D, L63CD
Jones (2012)136940136940JN669556PINA  L10I, T12A, I15V, E35D, M36I, R41K, R57K, Q61N, L63C, C67WD
 147603147603JN669694PINA  L10V, I15IV, G16E, M36I, R41K, K43R, R57K, Q61N, L63C, I93L, T96TAD
 159279159279JN669946PINAI47V, I54V, V82A, L90ML33F, G48W, F53L, Q58EL10V, I13V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, C67E, A71V, I93LD
 201750201750JN671235PINA  I13V, E35D, M36I, R41K, K43R, R57K, D60E, Q61D, I62V, L63C, T91VD
 202722202722JN671287PINA  I15V, E35D, M36I, R41K, R57RK, Q61D, L63C, I72ITD
 207065207065JN671420PINA  I13V, E35D, M36I, R41K, K45R, R57K, D60E, Q61N, L63C, I72T, L89LMD
Diaz (2015)RenG14846RenG14846KT745874PINAM46L, I54V, V82A, L90ML33FL10V, I15V, G16E, K20M, E35N, M36I, L38LF, R41K, K55R, R57K, Q61D, I62V, L63C, I64IL, E65ED, A71V, I72IT, T74S, T91A, I93LD
 RenG12504RenG12504KT743532PINAI50L T12I, G17E, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, I64V, V82I, L89MD
 RenG10962RenG10962KT741990PINA  L10V, E35D, M36I, R41K, R57K, Q61N, L63C, H69Y, I72V, I93LD
 RenG11277RenG11277KT742305PINA  L10I, I15IV, E35D, M36I, R41K, R57K, I62V, L63C, C67X, I72IVD