<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L63A
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 18
Isolates 19
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Montes (2004)MB_patGON02_GONC704AJ577901RTV, IDV, LPV137  I15V, E35D, M36I, R41K, I62V, L63AD
Non-B Workgroup (2005)TK5006TK5006 SQV, RTV, NFV79L90MQ58EL10I, R41K, L63A, I64V, I72V, V77I, I93LD
  TK5006b SQV, RTV, NFV, LPV160 Q58EL10I, R41K, L63A, I64V, I72V, V77VI, I93ILD
El-Khatib (2010)Pat11211ZA_SAVE2283JF960562LPV   T12S, I15V, L19I, M36I, R41K, L63A, H69K, I93LD
El Annaz (2012)97389738.PRJN185262PINA  I13IV, E35D, M36I, R41K, I62V, L63A, I64VD
Jones (2012)147583147583JN669693PINAI54V, V82T, L90M L10I, K20R, E35D, M36I, N37E, R41K, R57K, Q61N, L63A, E65D, A71V, T74S, I93LD
 169815169815JN670212PINA  L10V, T12S, I15V, E35D, M36I, R41K, R57K, D60E, Q61D, L63AD
 176324176324JN670393PINAD30N K20T, E35D, M36I, N37D, K45Q, R57K, D60E, Q61D, L63A, A71V, I93LD
 178114178114JN670471PINAI54V, V82A, L90M L10V, K20R, M36I, R41K, R57K, Q61N, L63A, A71V, T74S, I93LD
 195199195199JN670968PINAD30NL33F, N88DL10M, I13V, I15IV, E35D, M36L, R41K, R57K, Q61N, L63A, I93LD
 200723200723JN671206PINA  L10V, E35D, M36I, R41K, R57K, D60E, Q61D, L63AD
 205418205418JN671361PINAD30N K20T, E35DN, M36I, N37D, K45Q, R57K, D60E, Q61DN, L63A, A71V, I93IL, F99FSD
Diaz (2015)RenG17266RenG17266KT748294PINAM46MFIL, I54V, V82AL10FK20R, E34EG, E35D, M36I, N37ND, R41K, R57K, Q61N, L63A, H69CY, I72EV, L89MD
 RenG16876RenG16876KT747904PINAI50L, V82AL33FI13V, K20KT, E35D, M36I, R41K, L63A, A71V, T91SD
 RenG14430RenG14430KT745458PINA  L10I, I15V, E35D, M36I, R41K, I62V, L63A, C67D, I72TD
 RenG15051RenG15051KT746079PINA  W6W*, L10V, T12TI, I15V, G16E, E35D, M36I, R41K, R57K, Q61N, L63AD
 RenG13053RenG13053KT744081PINAV32I, M46L, G48GV, I50IL, V82A, L90ML33F, G73GS, L89VL10I, I13V, L19I, L24LF, E34EQ, E35ED, M36I, N37S, R41K, K55HQ, I62IV, L63A, I64L, A71VD
 RenG10317RenG10317KT741345PINAM46MI L10LI, K20R, E35D, M36I, R41K, P44PQ, L63A, I64V, E65D, K70R, N88NY, L89LMD
 RenG11258RenG11258KT742286PINA  L10I, I13IV, I15V, Q18L, E35D, M36I, R41K, R57RK, D60E, Q61D, L63AD