<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation Q58E
Rx PI-naive
IncludeMixtures No
References 19
Patients 25
Isolates 25
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Vergne (2000)LVMP976LVMP976AJ286969None  Q58EI15V, G16E, E35D, M36I, N37E, P39S, R41K, D60E, L63PD
Koulinska (2001)IK_96TZBF07196TZBF071AF289549None  Q58EI13V, L33V, E35D, N37S, R41K, L63P, H69YD
K'Aluoch (2005)OK_TC021304TC021304DQ079836None  Q58EI13V, M36I, R41K, L63PD
Vergne (2006)LV_02CM-CK1_1802CM-18AM181793None  Q58EL10V, E35D, M36IL, N37E, R41K, R57K, D60T, Q61D, L63P, H69QD
Koyalta (2009)74TCHAD-74FJ688204None  Q58ET4S, K14R, I15V, K20R, E35D, M36I, R41K, L89MD
 85TCHAD-85FJ688209None  Q58ET4S, K14R, I15V, K20R, E35D, M36I, R41K, L89MD
Ndembi (2010)DT2412_05_P12412GQ409606None  Q58EI13V, R41K, L63P, I64V, I72VD
 16535D_P116535GQ409634None  Q58EI13V, L19I, M36I, R41K, L63T, I64V, E65DD
Hamers (2011)CP076300894CP076300894HQ994969None  Q58EI13V, L33V, M36I, P39Q, R41K, I62IV, L63Q, I64V, E65D, I72VD
 CP076301867CP076301867HQ995002None  Q58EI13V, K20R, M36I, N37D, R41K, R57K, L63V, I64VD
Hamers (2012)CP076304853CP076304853JQ480241None  Q58EI13V, K20R, M36I, N37D, R41K, G52GS, R57K, L63V, I64VD
Karlsson (2012)SE_82SE_82JQ698720None  Q58EI13V, R41K, D60E, I62V, L63T, I64V, E65D, V77I, V82ID
Machado (2012)CUPL1096CUPL1096JN000068None  Q58ET12E, I15V, L19I, E35D, M36I, N37D, R41K, K43R, R57K, D60E, Q61E, L63P, H69Q, I93LD
Ssemwanga (2012)RCC_TDR-820974RCC_TDR-820974JQ266083None  Q58EI13V, K14R, L33V, R41K, I64V, E65DD
Youngpairoj (2012)cm182bbcm182bbDQ166435None  Q58EE35D, M36I, R41K, L63P, H69K, V77ID
Pircher (2013)A1022A1022JX110270None  Q58EM36I, R41K, L63P, E65EK, R87RKD
Sigaloff (2013)JCR077_0JCR077_0JX181994None  Q58EI13V, M36L, R41K, R57K, L63P, I64VD
Van Zyl (2013)O478174KC423369None  Q58EL10V, T12P, I13V, K20R, M36I, R41K, D60E, L63P, I64V, C67SD
Lee (2014)MBA1296MBA1296KJ906986None  Q58EI13V, L19LQ, L33V, R41K, I64VD
 MBA1158MBA1158KJ906856None  Q58EL10V, I13V, R41K, Q61E, L63P, I64VD
 MBA1364MBA1364KJ907050None  Q58EL10LI, I13V, K20KT, L33V, M36I, P39S, R41K, I62IV, I64V, H69HYD
Parczewski (2014)194_KR13194_KR13KM284025None  Q58EE35D, M36I, R41K, D60E, I64V, I72VD
Zeh (2016)3005470_053005470_05KU248740None  Q58EM36I, R41K, L63LP, T74KD
Kityo (2017)JCR008JCR008m0KT347889None  Q58EI13V, L33V, E35D, M36I, N37D, R41K, I64V, E65DD
 JCR077JCR077m0KT347953None  Q58EI13V, M36L, R41K, R57K, L63P, I64VD