<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation F53L
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 45
Isolates 45
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)113381113381AY365875PINAI54L, V82A, L90ML33F, K43T, F53LT12M, I13V, I15V, Q18H, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71I, I72LD
Baxter (2006)48-50525052-30515DQ878573PINAM46MI, G48M, I54V, V82A, L90MF53L, L89IVT4S, L10IV, I13V, K14R, G17DE, K20I, L33L_L, M36V, R41K, L63P, H69K, K70R, A71T, T74S, Q92KD
Dau (2010)09705A09705AGU581977PINAM46L, I54V, V82AT, I84V, L90ML33F, F53L, L89VL10I, I13V, I15V, K20T, E35D, M36I, N37D, K55R, D60E, I62V, L63P, I66F, K70E, A71V, Q92KD
Aulicino (2011)ARL636VSQARL636VSQFJ525813PINAM46I, I47V, I54V, V82AL24I, L33F, K43T, F53L, Q58EL10V, G16A, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71V, I93LD
 ARM522BCEARM522BCEFJ525832PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, K20R, E35N, M36I, K55R, R57K, Q61N, I62V, L63P, L89ID
Jones (2012)127508127508JN669438PINAI54V, V82A, L90ML33I, F53L, G73SL10I, I13V, K20R, E35D, M36I, R41K, K43KE, K55R, R57K, D60EK, Q61N, I62IV, L63P, A71IV, I72V, G94GD, C95LD
 159279159279JN669946PINAI47V, I54V, V82A, L90ML33F, G48W, F53L, Q58EL10V, I13V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, C67E, A71V, I93LD
 198096198096JN671100PINAM46L, I54V, V82A, L90MF53L, Q58E, T74PL10I, I15V, G16A, K20R, E35D, M36I, R41K, I62V, L63P, A71V, I85V, I93LD
 201210201210JN671216PINAI54V, V82T, I84VL33F, F53LL10I, I15V, K20R, E35D, M36I, N37D, R41K, Q61N, L63S, I64L, A71V, I72T, T74S, I85V, L89M, I93LD
 201919201919JN671244PINAI84V, L90MF53LL10I, T12I, I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, A71I, I72TD
 203943203943JN671324PINAV32I, M46I, I54V, V82AL24I, L33F, K43T, F53LL10I, I13V, G16E, K20R, E35D, M36I, N37D, P39PS, R57K, Q61N, L63S, E65D, K70Q, A71V, T74S, V77I, L89TD
Kouri (2012)CU25-10CU25-10JQ585358PINAM46L, I54V, V82A, L90ML33F, K43T, F53L, G73SL10V, I13V, L19LI, K20R, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71I, I93LD
 CU2073-09CU2073-09JQ585339PINAM46L, I54V, V82AF53LL10I, I13V, G16E, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, Q61H, L63T, E65D, I72T, T74A, L89MD
 CU90-10CU90-10JQ585361PINAI50V, I54L, L90ML10F, L33F, K43T, F53L, L89VQ2P, L5F, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37G, R41K, D60E, L63P, H69HY, A71IV, V77I, V82I, I93ILD
 CU311-10CU311-10JQ585381PINAI50V, I54L, L90ML33F, K43T, F53L, L89VV11L, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37D, R41K, D60E, L63P, H69Y, A71I, V77I, V82ID
Diaz (2015)RenG16786RenG16786KT747814PINAI54V, L90MF53L, G73SL10I, K14KE, I15V, K20R, E34EAD, E35D, M36I, R41K, L63P, A71VD
 RenG17129RenG17129KT748157PINAM46I, I54V, V82A, L90ML33F, K43T, F53L, G73SL10V, L19I, K20R, E35D, M36I, R41K, K55R, R57RK, I62V, L63P, C67L, H69Q, A71V, I72LD
 RenG15645RenG15645KT746673PINAM46I, I54V, I84V, L90ML10F, F53L, T74PI13V, K20R, E35D, M36I, R41K, K55H, R57K, L63P, H69R, A71V, L89I, T91S, Q92KD
 RenG16303RenG16303KT747331PINAL90ML33I, F53L, G73ST12I, I15V, Q18H, K20V, E35G, M36I, N37D, R41K, L63P, A71I, T74S, I85V, I93LD
 RenG16518RenG16518KT747546PINAM46I, I47V, I54V, V82A, L90MV11I, K43T, F53L, G73C, T74P, L89VL10V, T12K, I13A, I15V, L19I, K20I, E34Q, E35D, M36I, N37E, K55R, I62V, L63T, I72VD
 RenG15993RenG15993KT747021PINAM46L, I47V, L76V, V82TF53L, L89VL10V, I13V, I15V, Q18H, K20I, E34EK, E35EK, M36I, N37E, K55R, I62V, L63P, K70KT, A71V, V77ID
 RenG16880RenG16880KT747908PINAM46L, I54V, V82ML24I, F53LL10V, T12P, K20R, E35D, M36I, N37Q, R41K, L63P, A71V, V77I, I93LD
 RenG16697RenG16697KT747725PINAM46I, I47V, I54V, V82AF53LW6WG, L10I, I15V, K20R, E35D, M36I, R41K, I62V, L63P, C67SD
 RenG15602RenG15602KT746630PINAD30N, M46I, V82AL33I, F53L, N88DL10V, I13IV, G17GDE, K20R, E35D, M36I, N37D, D60E, I62V, L63P, I64IV, A71T, I72IT, V75VID
 RenG17271RenG17271KT748299PINAM46L, G48Q, I54V, L76V, V82AL33I, F53LL10V, I13V, K14KR, L19V, K20M, M36I, D60E, Q61N, I62IV, L63P, T74S, L89I, T91SD
 RenG13765RenG13765KT744793PINAM46I, I47V, I54V, V82AL24I, K43T, F53LL10V, L19I, K20R, E35D, M36I, N37H, R41K, R57K, Q61N, I62IV, L63V, I64V, E65D, I72V, T74SD
 RenG14584RenG14584KT745612PINAI54L, V82A, L90MV11I, L33F, K43T, F53L, G73SI13V, I15V, G16GCW, L19V, K20R, E21G, L24F, E35D, M36I, N37T, R41K, K55R, R57K, D60E, Q61H, I62V, L63P, A71V, I72FD
 RenG13694RenG13694KT744722PINAV32I, I47V, G48V, I54V, V82A, L90ML33F, F53L, Q58E, L89VL10I, I13V, K14E, I15V, K20R, E34Q, E35D, M36I, N37D, R41K, K55R, V56I, R57K, D60E, I62V, L63P, A71V, I85V, Q92KD
 RenG13605RenG13605KT744633PINAI50L, V82A, L90ML33F, F53L, Q58E, T74PSL10V, T12E, I13V, K14R, I15V, G16E, K20T, E35D, M36I, P39T, R41K, I62V, L63T, I64V, H69K, A71L, V77VL, I93LD
 RenG14586RenG14586KT745614PINAI54V, V82A, L90ML33F, F53LL10V, I13V, K20R, L24F, E35D, M36I, N37E, R41K, K55R, R57K, D60E, I62V, L63P, A71I, I93LD
 RenG12682RenG12682KT743710PINA F53L, G73SL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57RK, I62IV, L63LP, I64IV, A71AVD
 RenG13532RenG13532KT744560PINAD30N, M46L, I54IV, V82A, L90ML33F, F53L, N88DL10V, T12Q, I13V, I15V, G16GE, K20R, E35D, M36I, R41K, K55KN, Q61N, L63S, I93ILD
 RenG12299RenG12299KT743327PINAM46I, I54V, V82AL24I, L33F, F53L, T74PP9PR, L10I, T12TA, I13V, I15V, K20M, E35D, M36I, N37D, R41K, K45I, K55R, I62V, L63E, I64IV, E65D, L89MD
 RenG12639RenG12639KT743667PINAV32I, M46I, I47V, I54M, V82A, L90ML33F, F53L, T74TPL10I, I13V, G16GE, K20R, E34A, E35D, M36I, R41K, K45KR, K55KR, R57K, Q61N, L63S, C67E, I72V, V77VID
 RenG12915RenG12915KT743943PINAM46I, I50L, V82AL33F, F53LK20R, E34N, E35D, M36I, R41K, K55R, R57K, Q61D, L63P, E65D, A71TD
 RenG12729RenG12729KT743757PINAG48M, I54V, V82VA, L90ML33I, F53L, N83DL10V, T12I, I13A, A22V, E35H, M36I, N37NS, R41K, K43KQ, R57K, Q61N, I62V, L63P, H69Y, A71V, I72T, L89I, I93LD
 RenG12819RenG12819KT743847PINAI54V, V82S, L90ML33F, F53LQ7D, L10I, I13V, K20T, E34N, E35D, M36I, N37NT, R41K, I62V, L63AP, I64L, A71M, I72V, T74S, V77L, I93LD
 RenG13259RenG13259KT744287PINAI54V, V82A, L90ML33F, F53L, G73GAL10V, I13V, K20R, L24F, E35D, M36I, N37E, R41K, K55R, R57K, D60E, I62V, L63P, A71I, I93LD
 RenG11672RenG11672KT742700PINAD30N, M46L, I54V, V82ACGS, L90ML33LF, F53L, N88DI15V, K20T, E35N, M36I, N37NT, R41K, Q61H, I62V, L63P, I64L, A71F, V77IL, I93LD
 RenG11284RenG11284KT742312PINAD30N, M46L, I54V, V82ACGS, L90ML33LF, F53L, N88DI15V, K20T, E35N, M36I, N37NT, R41K, Q61H, I62V, L63P, I64L, A71F, V77IL, I93LD
 RenG11503RenG11503KT742531PINAM46I, I50V, I54V, V82AK43T, F53LL10V, I15V, K20T, E35D, M36I, N37D, R41K, L63LP, I64V, A71V, V77ID
 RenG10591RenG10591KT741619PINAL90ML23I, F53LL10I, T12K, I13L, I15V, L19Q, K20T, E35D, M36I, N37NADT, R41K, K55R, R57K, I62V, L63P, I66IV, A71V, T74S, V75ID
 RenG11414RenG11414KT742442PINAL90ML23I, F53L, G73SL10V, T12S, I15V, K20R, E35D, M36IV, N37NT, R41K, K45R, I62V, L63P, C67F, A71I, I72LD
 RenG10051RenG10051KT741079PINAL90ML23I, F53L, G73SL10LI, K14KN, I15V, K20T, E34EQ, E35D, M36I, R41K, K45R, I62IV, L63P, I66IV, A71IL, I72T, V77I, I93LD
 RenG11573RenG11573KT742601PINAM46I, I50L, V82AL33F, F53LK20R, E34N, E35D, M36I, R41K, K55R, R57K, Q61D, L63P, E65D, A71TD