<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation I50V
Rx >= 1 PI
IncludeMixtures No
References 3
Patients 9
Isolates 9
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Aulicino (2011)ARM522BCEARM522BCEFJ525832PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, K20R, E35N, M36I, K55R, R57K, Q61N, I62V, L63P, L89ID
Kouri (2012)CU90-10CU90-10JQ585361PINAI50V, I54L, L90ML10F, L33F, K43T, F53L, L89VQ2P, L5F, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37G, R41K, D60E, L63P, H69HY, A71IV, V77I, V82I, I93ILD
 CU311-10CU311-10JQ585381PINAI50V, I54L, L90ML33F, K43T, F53L, L89VV11L, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37D, R41K, D60E, L63P, H69Y, A71I, V77I, V82ID
Diaz (2015)RenG17021RenG17021KT748049PINAV32I, I47V, I50V, I54L, V82ML33F, K43T, T74PL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37S, R57K, Q61N, L63T, E65D, I72V, L89FD
 RenG15716RenG15716KT746744PINAI50V, I54V, V82AL33FL10V, I13V, G16A, L19I, K20R, M36I, N37D, L63P, A71T, I72V, L89I, L97F, N98KD
 RenG17358RenG17358KT748386PINAM46L, I50V, I54IV, V82VAL33F, Q58EL10V, I13IV, I15V, L19I, K20R, E35D, M36I, R41K, K55R, R57K, I62V, L63P, T74S, L89MD
 RenG11503RenG11503KT742531PINAM46I, I50V, I54V, V82AK43T, F53LL10V, I15V, K20T, E35D, M36I, N37D, R41K, L63LP, I64V, A71V, V77ID
 RenG10704RenG10704KT741732PINAM46I, I50V, V82AL33FL10V, K14R, I15V, Q18E, L19I, E35D, M36I, R41K, I62V, L63P, L89FD
 RenG10136RenG10136KT741164PINAD30N, I50V, I54V, V82A, L90LML33F, N88DL10V, I13V, K20R, E35D, M36I, N37E, R41Y, K45Q, R57K, Q61N, L63ST, E65D, A71L, L89LM, I93LD