<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation K43T
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 30
Isolates 30
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)113381113381AY365875PINAI54L, V82A, L90ML33F, K43T, F53LT12M, I13V, I15V, Q18H, K20R, E35D, M36I, N37DE, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71I, I72LD
Baxter (2006)48-22442244-30722DQ877883PINAV32I, M46I, I54V, V82A, L90MK43T, G73TL10V, I15V, K20R, M36I, R41N, K55R, D60E, L63P, H69HR, K70R, A71V, I93L, C95VD
Dau (2010)13578A13578AGU582074PINAV32I, M46I, I54V, L76V, I84V, L90ML10F, L33F, K43TI13V, K20R, E35D, M36I, R41RK, K55KR, D60E, L63P, I64V, L89ID
Margot (2010)2424HM116825PINAD30N, V32I, M46I, I47V, I54L, V82A, L90ML33F, K43T, F53L, N88D, L89VL10V, I13V, I15V, K20R, E35D, M36I, I62V, L63P, I66F, A71V, T74S, I93VD
Aulicino (2011)ARL636VSQARL636VSQFJ525813PINAM46I, I47V, I54V, V82AL24I, L33F, K43T, F53L, Q58EL10V, G16A, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71V, I93LD
 ARM522BCEARM522BCEFJ525832PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, K20R, E35N, M36I, K55R, R57K, Q61N, I62V, L63P, L89ID
 ARN397RLRARN397RLRFJ525859PINAM46L, I54L, V82T, I84VL24I, L33F, K43TE35D, M36I, N37E, R41K, R57K, D60N, Q61N, L63T, I64L, A71I, I72T, L89M, I93LD
Jones (2012)187807187807JN670741PINAM46L, I54V, V82A, L90ML33F, K43T, G73SQ7QH, L10V, I13V, K20R, E35D, M36I, L38LS, R41K, I62V, L63P, H69R, A71T, I72T, V77ID
 193544193544JN670904PINAI54LK43T, F53FL, G73ST12K, I13V, I15V, K20T, E35D, M36I, N37S, R41K, R57K, Q61D, I62V, L63P, E65ED, H69HY, A71T, I72R, T74S, V77I, I93IMD
 194025194025JN670920PINAM46L, I54V, V82A, L90ML33F, K43T, G73SL10I, I13L, Q18E, K20R, E34Q, E35D, M36I, K55R, R57K, Q61N, I62V, L63P, A71V, I72T, I93LD
 203943203943JN671324PINAV32I, M46I, I54V, V82AL24I, L33F, K43T, F53LL10I, I13V, G16E, K20R, E35D, M36I, N37D, P39PS, R57K, Q61N, L63S, E65D, K70Q, A71V, T74S, V77I, L89TD
Kouri (2012)CU25-10CU25-10JQ585358PINAM46L, I54V, V82A, L90ML33F, K43T, F53L, G73SL10V, I13V, L19LI, K20R, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71I, I93LD
 CU90-10CU90-10JQ585361PINAI50V, I54L, L90ML10F, L33F, K43T, F53L, L89VQ2P, L5F, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37G, R41K, D60E, L63P, H69HY, A71IV, V77I, V82I, I93ILD
 CU311-10CU311-10JQ585381PINAI50V, I54L, L90ML33F, K43T, F53L, L89VV11L, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37D, R41K, D60E, L63P, H69Y, A71I, V77I, V82ID
Diaz (2015)RenG17129RenG17129KT748157PINAM46I, I54V, V82A, L90ML33F, K43T, F53L, G73SL10V, L19I, K20R, E35D, M36I, R41K, K55R, R57RK, I62V, L63P, C67L, H69Q, A71V, I72LD
 RenG16518RenG16518KT747546PINAM46I, I47V, I54V, V82A, L90MV11I, K43T, F53L, G73C, T74P, L89VL10V, T12K, I13A, I15V, L19I, K20I, E34Q, E35D, M36I, N37E, K55R, I62V, L63T, I72VD
 RenG17021RenG17021KT748049PINAV32I, I47V, I50V, I54L, V82ML33F, K43T, T74PL10I, I13V, I15V, G16E, K20R, E35D, M36I, N37S, R57K, Q61N, L63T, E65D, I72V, L89FD
 RenG16020RenG16020KT747048PINAM46I, I54A, V82AL24I, K43TL10I, I15IV, K20R, E35D, M36I, N37H, R41K, I62V, L63E, I64V, A71V, I72V, V77I, I93LD
 RenG13765RenG13765KT744793PINAM46I, I47V, I54V, V82AL24I, K43T, F53LL10V, L19I, K20R, E35D, M36I, N37H, R41K, R57K, Q61N, I62IV, L63V, I64V, E65D, I72V, T74SD
 RenG14584RenG14584KT745612PINAI54L, V82A, L90MV11I, L33F, K43T, F53L, G73SI13V, I15V, G16GCW, L19V, K20R, E21G, L24F, E35D, M36I, N37T, R41K, K55R, R57K, D60E, Q61H, I62V, L63P, A71V, I72FD
 RenG15039RenG15039KT746067PINAM46I, G48S, I54S, V82ML24I, K43TL10V, L19IV, K20R, E35D, M36I, R41K, F53Y, K55Q, R57K, D60DN, Q61DN, I62V, L63T, I64V, E65D, I72T, T74AD
 RenG13674RenG13674KT744702PINAV82A, L90ML33F, K43T, G73SL10V, I13V, I15V, L19I, K20T, E35D, M36I, R41K, L63P, A71V, T74S, V77I, I93LD
 RenG13639RenG13639KT744667PINAM46ML, I50L, V82AL33F, K43TT12A, I13V, K14R, I15V, E35D, M36I, R41K, R57K, L63P, I64VD
 RenG12426RenG12426KT743454PINAM46I, I54V, V82S, I84VK43T, L89VL10I, I15V, L19IV, K20R, M36I, I62IV, L63P, K70R, A71V, I72M, Q92KD
 RenG12305RenG12305KT743333PINAM46L, I54V, V82AL24I, L33F, K43TL10V, I15V, K20R, E35D, M36I, R41K, I62V, L63PD
 RenG12984RenG12984KT744012PINAM46I, I54V, V82A, I84V, L90ML33F, K43T, G73TL10V, L19V, K20R, E35D, M36I, R41N, D60E, Q61D, I62V, L63P, H69Y, A71T, I72TD
 RenG10098RenG10098KT741126PINAM46L, I54V, V82AV11I, L24I, K43TL10V, I13V, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71T, I72TD
 RenG11287RenG11287KT742315PINAM46I, I54V, V82A, L90ML10F, K43T, G73TQ7DE, P9PL, I13M, I15V, K20I, E21EQ, E35N, M36I, R41RK, K55R, R57RK, I62IV, L63P, I64V, A71V, I72T, I85V, I93LD
 RenG11503RenG11503KT742531PINAM46I, I50V, I54V, V82AK43T, F53LL10V, I15V, K20T, E35D, M36I, N37D, R41K, L63LP, I64V, A71V, V77ID
 RenG10374RenG10374KT741402PINAV32I, M46I, I47V, I54M, V82AL24I, K43T, L89VL10V, I13V, K20R, E35D, M36I, K55R, R57RK, L63P, A71I, I72VD