<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation K43T
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 12
Isolates 12
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Baxter (2006)12-17561756-30527DQ876870PINAI54V, V82A, L90MK43T, G73SL10I, I15V, K20R, E35D, M36I, I62V, L63P, H69R, A71VD
 48-22442244-30722DQ877883PINAV32I, M46I, I54V, V82A, L90MK43T, G73TL10V, I15V, K20R, M36I, R41N, K55R, D60E, L63P, H69HR, K70R, A71V, I93L, C95VD
 48-30833083-30313DQ877992PINAV32I, M46I, I47V, I54V, V82A, L90MK43T, F53L, G73S, L89VL10V, T12I, I13V, G16A, K20I, M36I, K55R, L63P, A71VD
 48-71347134-30729DQ878972PINAV32I, M46L, V82A, L90MK43T, L89VI13V, K20R, M36I, I62V, L63P, A71VD
Waleria-Aleixo (2008)08PR06075308PR060753FJ591549PINAV32I, M46MI, I54V, L90ML33I, K43T, F53LL10V, I13V, G16E, L19LI, K20M, E35EG, M36I, L63R, I66F, H69R, A71V, I72IVD
 08PR05023208PR050232FJ591261PINAI54L, V82A, L90ML33F, K43T, F53LL10V, I13V, I15IV, K20R, E35D, M36I, R41K, I62V, L63P, H69K, A71I, T74S, I93IMD
Kouri (2012)CU25-10CU25-10JQ585358PINAM46L, I54V, V82A, L90ML33F, K43T, F53L, G73SL10V, I13V, L19LI, K20R, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71I, I93LD
 CU90-10CU90-10JQ585361PINAI50V, I54L, L90ML10F, L33F, K43T, F53L, L89VQ2P, L5F, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37G, R41K, D60E, L63P, H69HY, A71IV, V77I, V82I, I93ILD
 CU311-10CU311-10JQ585381PINAI50V, I54L, L90ML33F, K43T, F53L, L89VV11L, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37D, R41K, D60E, L63P, H69Y, A71I, V77I, V82ID
Diaz (2015)RenG15295RenG15295KT746323PINAV32I, M46I, I47V, I50V, I54L, L90MK43T, L89VT12K, I15V, L19I, K20T, E35D, M36I, N37E, R57K, A71V, I85VD
 RenG12426RenG12426KT743454PINAM46I, I54V, V82S, I84VK43T, L89VL10I, I15V, L19IV, K20R, M36I, I62IV, L63P, K70R, A71V, I72M, Q92KD
 RenG12305RenG12305KT743333PINAM46L, I54V, V82AL24I, L33F, K43TL10V, I15V, K20R, E35D, M36I, R41K, I62V, L63PD