<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation K43R
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 35
Isolates 35
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cuevas (2002)CU105CU105AF425486IDV   G16D, M36I, R41K, K43R, Q61E, L63P, H69K, I93LD
 CU104CU104AF425485IDV   E35D, M36I, R41K, K43R, D60E, L63P, H69QD
 CU80CU80AF425461IDV   L10V, E35D, M36I, R41K, K43R, L63P, H69Q, V82ID
 CU54CU54AF425435SQV, IDV   I13V, E35D, M36I, N37D, R41K, K43R, L63PD
 CU51CU51AF425432IDV   I15V, M36I, N37D, R41K, K43R, L63P, H69QD
Non-B Workgroup (2005)TK3037TK3037 RTV196I54V, V82A L10V, T12TA, I13V, K14R, G16A, R41K, K43R, I62V, L63P, A71TD
Aulicino (2011)ARL411LCOARL411LCOFJ525808PINAD30NN88DL10Y, I13V, I15V, K20T, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63H, I72V, V75ID
Jones (2012)147603147603JN669694PINA  L10V, I15IV, G16E, M36I, R41K, K43R, R57K, Q61N, L63C, I93L, T96TAD
 162542162542JN670041PINA  L10I, I15V, K20R, M36I, R41K, K43R, R57K, Q61N, L63T, C67S, I93LD
 163678163678JN670068PINAL90LM L10V, I13V, I15V, K20T, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, I64L, I72T, T74S, I93LD
 185340185340JN670703PINA  I15V, E35D, M36I, R41K, K43R, R57K, L63TD
 201750201750JN671235PINA  I13V, E35D, M36I, R41K, K43R, R57K, D60E, Q61D, I62V, L63C, T91VD
 205762205762JN671371PINA  E35D, M36I, R41K, K43R, K55KE, R57K, Q61D, L63P, L89LPD
Kouri (2012)CU1373-09CU1373-09JQ585294PINAV32I, M46L, L76V, V82AL10F, L33F, L89VI13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92KD
 CU1484-09CU1484-09JQ585298PINA  W6G, I15V, Q18E, K20R, E35D, M36I, R41K, K43R, I62V, L63P, H69QD
 CU547-11CU547-11JQ585510PINA  I13V, K14R, M36I, N37D, R41K, K43R, Q61E, L63P, H69QD
 CU503-10CU503-10JQ585401PINA  E35D, M36I, R41K, K43R, L63P, H69Q, I72VD
 CU322-11CU322-11JQ585490PINA  E35D, M36I, R41K, K43R, Q61H, I62V, L63P, H69Q, V82ID
 CU1267-09CU1267-09JQ585282PINA  T12A, I15IV, L19I, E35D, M36I, N37D, R41K, K43R, D60E, I62IV, L63P, I64IV, H69QD
 CU1640-09CU1640-09JQ585304PINA  M36I, R41K, K43R, L63P, H69QD
 CU1270-09CU1270-09JQ585285PINA  I15V, G16E, K20M, P39S, R41K, K43R, Q61N, L63P, V77ID
 CU403-10CU403-10JQ585455PINA  K14R, M36I, N37D, R41K, K43R, L63P, H69QD
 CU1998-10CU1998-10JQ585448PINA  M36I, R41K, K43R, I62IV, L63P, H69Q, V82ID
 CU116-10CU116-10JQ585365PINA  E35D, M36I, R41K, K43R, R57K, I62V, L63P, I64V, H69Q, A71T, V77I, I93LD
 CU1264-11CU1264-11JQ585520PINA  M36I, R41K, K43R, I62V, L63P, H69QD
 CU2102-09CU2102-09JQ585349PINA  M36I, R41K, K43R, I62V, L63P, H69Q, V82ID
 CU736-10CU736-10JQ585412PINA  E35D, M36I, R41K, K43R, L63P, H69Q, I72IV, V82I, I93ILD
 CU422-11CU422-11JQ585500PINA  T12P, L19I, E35D, M36I, R41K, K43R, L63P, I93LD
 CU2072-09CU2072-09JQ585348PINA  M36I, R41K, K43R, L63P, H69QD
 CU646-09CU646-09JQ585260PINA  Q7L, K20R, E21EK, E35D, M36I, N37D, R41K, K43R, G52GS, Q61EG, L63P, H69QD
 CU1708-09CU1708-09JQ585308PINA  L10V, E21K, E35D, M36I, R41K, K43R, I62V, L63P, H69Q, A71T, I72IT, I93LD
 CU1959-09CU1959-09JQ585326PINAM46L, I54L, V82T, L90ML33F, T74PL10I, I13V, E35D, M36I, R41K, K43R, K55R, L63P, H69Q, A71V, I93LD
 CU2043-09CU2043-09JQ585337PINA  I15V, K20R, E35D, M36I, R41K, K43R, I62V, L63P, H69Q, K70E, A71T, I93LD
 CU1283-09CU1283-09JQ585286PINA  T12A, I15IV, L19I, E35D, M36I, N37D, R41K, K43R, D60E, I62IV, L63P, I64IV, H69QD
 CU949-09CU949-09JQ585268PINA  E35D, M36I, R41K, K43R, L63P, H69Q, I72VD