<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation M36L
Rx PI-naive
IncludeMixtures No
References 16
Patients 30
Isolates 31
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Eshleman (2004)ESH_Pat104ESH218AY435246None   I13V, K20KR, M36L, R41K, K43KR, L63P, I64V, K70KR, I72V, V77ID
 ESH_Pat143ESH519AY435299None   I13V, K20R, M36L, N37A, R41K, Q61H, I64VD
Church (2007)218-118871V218EF612016None   I13V, K20KR, M36L, R41K, K43KR, L63P, I64V, K70KR, I72V, V77ID
 452-125040D452EF612032None   I13V, M36L, N37NS, R41K, I64V, H69HYD
 519-128295D519EF612055None   I13V, K20R, M36L, N37A, R41K, Q61H, I64VD
Galluzzo (2007)M20490UG_M20490JQ220111None   I13V, L33V, M36L, R41K, I62V, L63S, I64V, E65DD
Brumme (2009)G3542G3542GQ371895None   T12IKM, G16GE, E35D, M36L, N37E, R41K, R57K, I62V, L63T, I64V, H69YD
Hamers (2011)CP076301544CP076301544HQ993587None   I13V, L19LI, M36L, R41K, L63P, I72M, L89LFD
 CP076301572CP076301572HQ993612None   I13V, L33V, M36L, R41K, R57K, D60E, I62V, I64V, K70KRD
 CP076301623CP076301623HQ993659None   M36L, N37D, R41K, L63Q, I64VD
 CP076304223CP076304223HQ993918None   L10I, I13V, G17E, M36L, P39P*QS, R41K, Q61H, I62V, L63T, I64V, E65DD
 CP076302980CP076302980HQ995057None   I13V, M36L, R41K, I62V, I64VD
 CP076302992CP076302992HQ995064None   I15V, M36L, N37D, R41K, L63P, I64V, H69Y, K70T, I72T, T91TAD
 CP076303041CP076303041HQ995225None   L10V, I13V, M36L, R41K, D60E, Q61E, I62V, L63P, I64VD
 CP076303056CP076303056HQ995237None   L10V, I13V, M36L, N37D, R41K, L63P, I64V, H69Y, K70T, I72TD
 CP076301968CP076301968HQ995432None   I13V, G16E, M36L, R41K, I64VD
 CP076301999CP076301999HQ995451None   I13V, I15V, M36L, R41K, I64VD
Chen (2012)YN10DH0062YN10DH0062JQ658685None   T12TA, K14R, L19I, M36L, R41K, R57K, I62IV, L63P, V82I, I93LD
Mollan (2012)MK157MK157w0 None   K14R, M36L, N37D, D60E, I62V, L63P, I64VD
  MK157w85 None   T12A, K14R, M36L, N37D, D60E, I62V, L63P, I64VD
Sigaloff (2012)KELKN210KELKN210JN628484None   L10V, I13V, I15V, M36L, R41K, L63Q, I64VD
Ssemwanga (2012)RCC_TDR_483540RCC_TDR_483540JQ266071None   L19V, M36L, R41K, L63S, I64V, E65DD
Bila (2013)MZ10-212HIV-1KF927311None   T12S, K14KR, I15V, L19T, M36L, N37Q, R41K, D60E, I62V, L63P, H69K, I72M, L89MD
Brooks (2013)CAN2013-116CAN13-116KF727755None  L89MVL10IV, I13V, I15IV, G16E, E35D, M36L, R41K, R57K, L63TD
Kiptoo (2013)KAP043KAP043KC516905None   I13V, M36L, R41K, I62V, L63A, I64V, K70KR, V75I, V82VID
 SNH024SNH024KC516940None   I13V, K14R, M36L, R41K, Q61H, I64V, K70RD
Sigaloff (2013)JCR047_0JCR047_0JX181988None   P1L, L10V, I13V, G16A, K20M, M36L, R41K, I64V, V75ID
 JCR077_0JCR077_0JX181994None  Q58EI13V, M36L, R41K, R57K, L63P, I64VD
Chung (2014)KTA_42_KA243eKTA_42_KA243eKF544248None   M36L, R41K, R57K, D60E, I62V, L63P, I64V, V77ID
Budambula (2015)MK44MK44KP792038None   K14R, G16E, K20R, T31A, M36L, R41K, D60E, I64VD
Hora (2015)DEURF09KE004DEURF09KE004KP174771None   I13V, K14R, K20R, M36L, N37D, R41K, L63P, I64V, K70Q, I72VD