<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation E35N
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 19
Isolates 19
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Koyalta (2009)68TCHAD-68FJ688199IDV26M46I, L76V T12P, I15V, L19V, K20I, E35N, M36I, N37D, R41K, R57K, D60E, I62V, L63P, I64V, K70R, I85VD
Aulicino (2011)ARM522BCEARM522BCEFJ525832PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, K20R, E35N, M36I, K55R, R57K, Q61N, I62V, L63P, L89ID
 444-O288CCR444-O288CCRHQ158164PINAD30NN88DL10I, I13V, I15V, K20T, E35N, M36I, R41K, Q61N, L63P, I72T, T74M, V77I, I93LD
 321-L82321-L82HQ158268PINAL90M I15V, K20T, E35N, M36I, R41K, I62V, L63P, T74SD
Jones (2012)159048159048JN669940PINAV32I, I47V, I54M, L90MV11VIL10I, T12K, I13IV, K20I, E21ED, E35N, M36I, R41K, R57K, Q61N, L63P, I64IV, T74S, V82I, I85VD
Diaz (2015)RenG17296RenG17296KT748324PINAV32I, M46I, I54V, L90ML33I, G73S, N83DL10I, I15IV, Q18E, K20R, E35N, M36I, R41K, R57K, Q61D, L63P, C67Y, G68E, H69Y, A71V, I72RD
 RenG15734RenG15734KT746762PINAM46I, I54V, V82F, I84V L10V, I15V, K20T, E35N, M36I, R41K, I62V, L63P, I64IV, T74AD
 RenG15826RenG15826KT746854PINA  E35N, M36I, N37E, R41K, I62V, L63P, I64V, E65D, V77ID
 RenG15014RenG15014KT746042PINAM46I, I54A, V82AL33I, Q58E, N83DL10V, I13A, K14R, K20R, A22V, E35N, M36I, N37D, I62V, L63P, I64V, H69K, A71V, Q92KD
 RenG14846RenG14846KT745874PINAM46L, I54V, V82A, L90ML33FL10V, I15V, G16E, K20M, E35N, M36I, L38LF, R41K, K55R, R57K, Q61D, I62V, L63C, I64IL, E65ED, A71V, I72IT, T74S, T91A, I93LD
 RenG14682RenG14682KT745710PINAM46I, I54V, V82AN88DL10V, I13V, I15V, G16E, K20I, E35N, M36I, R41K, K45R, K55KR, R57K, Q61N, L63Q, I64V, T74SD
 RenG14833RenG14833KT745861PINAM46ML, I54V, V82F, L90M L10V, I13V, I15V, K20IT, E35N, M36I, N37D, R41K, R57K, D60E, Q61N, L63P, I64IV, T74S, V77I, L89LIM, I93LD
 RenG12217RenG12217KT743245PINAM46I, I54V, V82F, L90M L10I, I15V, K20T, E35N, M36I, R41KT, K43Q, R57K, D60N, Q61D, I62V, L63P, I64L, V77I, L89I, I93LD
 RenG11287RenG11287KT742315PINAM46I, I54V, V82A, L90ML10F, K43T, G73TQ7DE, P9PL, I13M, I15V, K20I, E21EQ, E35N, M36I, R41RK, K55R, R57RK, I62IV, L63P, I64V, A71V, I72T, I85V, I93LD
 RenG11672RenG11672KT742700PINAD30N, M46L, I54V, V82ACGS, L90ML33LF, F53L, N88DI15V, K20T, E35N, M36I, N37NT, R41K, Q61H, I62V, L63P, I64L, A71F, V77IL, I93LD
 RenG11284RenG11284KT742312PINAD30N, M46L, I54V, V82ACGS, L90ML33LF, F53L, N88DI15V, K20T, E35N, M36I, N37NT, R41K, Q61H, I62V, L63P, I64L, A71F, V77IL, I93LD
 RenG10904RenG10904KT741932PINAI54L L10V, I15V, G16E, K20A, E35N, M36I, P39S, R41K, R57K, D60E, I62V, L63T, I64L, E65ED, A71V, I72T, I93LD
 RenG10437RenG10437KT741465PINAI54V, V82A, L90M L10V, T12E, I15V, L19I, K20T, E35N, M36I, R41K, I62V, L63P, I64M, A71V, T74S, I93LD
 RenG11215RenG11215KT742243PINAM46L, I54V, V82F, I84V, L90ML33F, Q58EL10IV, I15V, K20KR, E35N, M36IV, N37E, R41K, R57RK, I62V, I64V, A71V, I93LD