<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L33I
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 13
Isolates 13
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Laurent (2006)CK2-8402CM-84AM279448NFV105 L10F, L33I, N88GI13V, E35D, M36I, N37E, R41K, V56A, I62V, L63P, H69Y, A71T, I72TD
Jones (2012)127508127508JN669438PINAI54V, V82A, L90ML33I, F53L, G73SL10I, I13V, K20R, E35D, M36I, R41K, K43KE, K55R, R57K, D60EK, Q61N, I62IV, L63P, A71IV, I72V, G94GD, C95LD
 170719170719JN670232PINAI54V, V82A, L90ML33IL10I, I13V, K14R, K20M, E35D, M36I, N37D, R41K, Q61N, L63P, A71T, I72TD
Reynolds (2012)B0715B0715-2JN652205LPV  L33II13V, M36T, P39S, R41K, L63S, I64VD
Thiam (2013)3259-HALD3259-HALDKC176537LPV I54A, V82FL33IL10V, I13V, E35D, M36I, R41K, K45V, I62V, L63D, I64V, I72TD
Diaz (2015)RenG16303RenG16303KT747331PINAL90ML33I, F53L, G73ST12I, I15V, Q18H, K20V, E35G, M36I, N37D, R41K, L63P, A71I, T74S, I85V, I93LD
 RenG17296RenG17296KT748324PINAV32I, M46I, I54V, L90ML33I, G73S, N83DL10I, I15IV, Q18E, K20R, E35N, M36I, R41K, R57K, Q61D, L63P, C67Y, G68E, H69Y, A71V, I72RD
 RenG15602RenG15602KT746630PINAD30N, M46I, V82AL33I, F53L, N88DL10V, I13IV, G17GDE, K20R, E35D, M36I, N37D, D60E, I62V, L63P, I64IV, A71T, I72IT, V75VID
 RenG17271RenG17271KT748299PINAM46L, G48Q, I54V, L76V, V82AL33I, F53LL10V, I13V, K14KR, L19V, K20M, M36I, D60E, Q61N, I62IV, L63P, T74S, L89I, T91SD
 RenG16451RenG16451KT747479PINAD30NL10F, L33I, N88DQ7E, K20T, E35DN, M36I, R41K, R57K, D60E, Q61E, L63P, I72VD
 RenG15014RenG15014KT746042PINAM46I, I54A, V82AL33I, Q58E, N83DL10V, I13A, K14R, K20R, A22V, E35N, M36I, N37D, I62V, L63P, I64V, H69K, A71V, Q92KD
 RenG12729RenG12729KT743757PINAG48M, I54V, V82VA, L90ML33I, F53L, N83DL10V, T12I, I13A, A22V, E35H, M36I, N37NS, R41K, K43KQ, R57K, Q61N, I62V, L63P, H69Y, A71V, I72T, L89I, I93LD
 RenG11212RenG11212KT742240PINAD30N, I54LL10F, L33I, N83D, N88DI13V, K14R, A22V, E34N, M36I, N37D, L63P, H69K, A71V, I72V, T74SD