<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L24I
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 13
Isolates 15
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)TK1009TK1009a IDV, NFV, RTV, LPV239M46I, I54V, V82AL24IL10I, M36I, N37D, R41K, L63P, I64V, A71AV, I72VD
 TK1028TK1028 RTV, IDV, NFV207M46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028a RTV, IDV, NFV231M46I, I54V, V82TL24IP1PS, L10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
  TK1028b RTV, IDV, NFV308M46L, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
Baxter (2006)48-12121212-30812DQ877754PINAM46L, I54V, V82AL24I, L33FL10V, I15V, E35D, M36I, N37ND, R41K, I62V, L63PD
 48-14291429-30424DQ877819PINAM46I, I54V, V82TL24IL10I, I13V, E35D, M36I, N37S, R41K, K55R, L63P, I64V, A71V, I72V, V77I, I93LD
 48-41654165-30410DQ878398PINAM46MI, I54V, V82SL24IL10I, I13V, L19I, K20IM, M36I, R41K, L63P, A71VD
 48-92949294-30930DQ877624PINAM46MI, V82AL24IL10I, I15IV, E35D, M36I, N37ND, R41K, I62V, L63P, T74SD
 48-90069006-30923DQ877670PINAI54A, V82AL24I, Q58E, L89VL10Y, I13IMV, I15V, K20I, E34KQ, E35D, M36I, N37NS, R41K, R57K, D60E, I62IV, L63P, A71V, I93LD
von Wyl (2007)1285248038EF449884PINAL90ML24IL10I, I13V, E35G, M36I, R41K, I62V, L63P, A71T, T74A, V75ID
Waleria-Aleixo (2008)08PR06072008PR060720FJ591542PINAI54V, V82TL24I, F53LL10V, I13V, K20R, E35D, M36V, N37T, R41K, R57K, I62V, L63P, I64V, A71V, T74SD
Kouri (2012)CU373-10CU373-10JQ585388PINAM46I, I54V, L76V, V82AL24I, L33FL10I, I13V, K20R, E35D, M36I, N37D, R41K, D60E, I62V, L63P, A71V, I93LD
 CU1209-09CU1209-09JQ585279PINAM46L, I54M, V82AL10F, L24I, L33F, Q58EI13V, K20R, M36I, R41K, K43KR, I62V, L63P, E65ED, A71VD
Diaz (2015)RenG12305RenG12305KT743333PINAM46L, I54V, V82AL24I, L33F, K43TL10V, I15V, K20R, E35D, M36I, R41K, I62V, L63PD
 RenG11659RenG11659KT742687PINAM46L, V82AL24I, Q58EL10V, I15V, L19I, K20R, M36I, R41K, L63P, I64L, H69K, I72V, L89MD