<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation K20T
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 53
Isolates 53
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gomez-Carrillo (2004)118423118423AY365949PINAL90M L10V, I13V, K14R, K20T, E35D, M36I, N37D, R41K, Q61N, L63P, A71T, I72T, T74SD
Non-B Workgroup (2005)TK3003TK3003 SQV, NFV247I54V, L90M K20T, E35D, M36I, N37DE, R41K, D60E, I62V, L63S, I64V, V77VI, V82ID
 TK3011TK3011 SQV, NFV231D30NN88DI13V, I15V, K20T, E35D, M36I, N37NY, R41K, I64V, T74SD
Rhee (2005)ASRU017ASRU017 SQV, IDV, RTV91I84V, L90M L10I, T12S, I15V, K20T, E35G, M36I, R41K, I64V, A71T, I85V, I93LD
Baxter (2006)48-80168016-30826DQ879061PINAM46L, I54LL10F, Q58EI13V, K20T, E35ED, M36I, N37ND, R41K, L63Q, I64VD
Dau (2010)07867A07867AGU581877PINAV32I, M46I, I47A, L90ML10F, L89VT4A, I13V, K20T, L33V, I62V, L63P, H69Y, A71V, I93LD
 09705A09705AGU581977PINAM46L, I54V, V82AT, I84V, L90ML33F, F53L, L89VL10I, I13V, I15V, K20T, E35D, M36I, N37D, K55R, D60E, I62V, L63P, I66F, K70E, A71V, Q92KD
Aulicino (2011)ARL411LCOARL411LCOFJ525808PINAD30NN88DL10Y, I13V, I15V, K20T, E35D, M36I, N37D, R41K, K43R, R57K, Q61N, L63H, I72V, V75ID
 ARN571EAEARN571EAEFJ525863PINA  L10V, I13V, K14N, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, E65D, A71T, T74S, Q92KD
 444-O288CCR444-O288CCRHQ158164PINAD30NN88DL10I, I13V, I15V, K20T, E35N, M36I, R41K, Q61N, L63P, I72T, T74M, V77I, I93LD
 321-L82321-L82HQ158268PINAL90M I15V, K20T, E35N, M36I, R41K, I62V, L63P, T74SD
Jones (2012)134612134612JN669531PINAL90M I15V, K20T, E35EDG, M36I, R41K, I64V, T74TS, V75VI, I93ILD
 162069162069JN670025PINAL90M L10V, I13V, I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, L63P, A71V, T74S, I93LD
 163678163678JN670068PINAL90LM L10V, I13V, I15V, K20T, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, I64L, I72T, T74S, I93LD
 176324176324JN670393PINAD30N K20T, E35D, M36I, N37D, K45Q, R57K, D60E, Q61D, L63A, A71V, I93LD
 182041182041JN670597PINAL90M L10V, I13V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, I93LD
 182997182997JN670632PINAL90M L10LV, I13V, L19I, K20T, E35D, M36I, R41K, Q61N, L63P, A71AT, T74S, I93LD
 185997185997JN670710PINAL90M L10I, I13V, K20T, E35D, M36I, R41K, R57RK, D60E, Q61N, I62V, L63T, I64L, C67D, I72T, V82VI, I93LD
 189796189796JN670781PINAI54V, L90ML23LIL10V, I13V, I15V, L19LV, K20T, E35D, M36I, N37D, R41RK, R57K, D60E, Q61D, I62V, L63P, A71I, T74S, I93LD
 193544193544JN670904PINAI54LK43T, F53FL, G73ST12K, I13V, I15V, K20T, E35D, M36I, N37S, R41K, R57K, Q61D, I62V, L63P, E65ED, H69HY, A71T, I72R, T74S, V77I, I93IMD
 201919201919JN671244PINAI84V, L90MF53LL10I, T12I, I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, A71I, I72TD
 202598202598JN671278PINAL90M L10V, I15V, K20T, E35D, M36I, N37ND, R41K, R57K, Q61D, L63P, I72T, I93LD
 202646202646JN671284PINAI54L, L90ML33FL10V, I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, L63H, T74S, Q92QKD
 204389204389JN671339PINAD30N, M46IN88DL10I, I15V, G17E, K20T, M36I, N37K, R41K, R57K, Q61D, L63P, I72R, I93LD
 205418205418JN671361PINAD30N K20T, E35DN, M36I, N37D, K45Q, R57K, D60E, Q61DN, L63A, A71V, I93IL, F99FSD
 207305207305JN671429PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, K20T, E35D, M36I, R41K, D60E, Q61N, I62V, L63T, I64L, C67D, A71V, I72T, I93LD
Kouri (2012)CU90-10CU90-10JQ585361PINAI50V, I54L, L90ML10F, L33F, K43T, F53L, L89VQ2P, L5F, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37G, R41K, D60E, L63P, H69HY, A71IV, V77I, V82I, I93ILD
 CU311-10CU311-10JQ585381PINAI50V, I54L, L90ML33F, K43T, F53L, L89VV11L, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37D, R41K, D60E, L63P, H69Y, A71I, V77I, V82ID
Diaz (2015)RenG16031RenG16031KT747059PINAL90MV11IL10I, I15V, L19Q, K20T, E35G, M36I, P39S, R41K, I62V, L63P, H69Y, A71V, I72L, T74SD
 RenG15734RenG15734KT746762PINAM46I, I54V, V82F, I84V L10V, I15V, K20T, E35N, M36I, R41K, I62V, L63P, I64IV, T74AD
 RenG17066RenG17066KT748094PINAI54L, L90MG73SI15IV, K20T, E35D, M36I, R41K, K45KR, L63P, A71VD
 RenG17196RenG17196KT748224PINAD30N, L90LML10F, Q58E, N88DI13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, L63HQ, I64VD
 RenG17468RenG17468KT748496PINAM46I, I54V, V82A, N88SL24I, L33F, Q58EL10I, I13V, I15V, K20T, E35G, M36I, R41K, K55KR, D60E, I62V, L63P, A71TD
 RenG17301RenG17301KT748329PINAI50LV32A, L33F, Q58EL10V, I13V, L19I, K20T, E34N, E35D, M36I, L63P, I64IL, A71V, I72T, V77IL, I93LD
 RenG15911RenG15911KT746939PINAL90MG73GSI13V, I15V, K20T, E35D, M36I, R41K, I62V, L63P, A71AITV, T74SD
 RenG16451RenG16451KT747479PINAD30NL10F, L33I, N88DQ7E, K20T, E35DN, M36I, R41K, R57K, D60E, Q61E, L63P, I72VD
 RenG15415RenG15415KT746443PINAM46I, N88SQ58EL10V, I13IV, I15V, K20T, K55KR, L63P, A71V, V77I, T91SD
 RenG14658RenG14658KT745686PINAL90M L10V, I15V, K20T, E35D, M36I, P39PS, R41K, Q61QH, I62V, L63P, T74S, I93LD
 RenG13605RenG13605KT744633PINAI50L, V82A, L90ML33F, F53L, Q58E, T74PSL10V, T12E, I13V, K14R, I15V, G16E, K20T, E35D, M36I, P39T, R41K, I62V, L63T, I64V, H69K, A71L, V77VL, I93LD
 RenG13674RenG13674KT744702PINAV82A, L90ML33F, K43T, G73SL10V, I13V, I15V, L19I, K20T, E35D, M36I, R41K, L63P, A71V, T74S, V77I, I93LD
 RenG15170RenG15170KT746198PINA G73STL10V, T12S, I15V, K20T, E35D, M36I, N37DE, R41K, K43KR, I62V, L63P, T74S, I93LD
 RenG12217RenG12217KT743245PINAM46I, I54V, V82F, L90M L10I, I15V, K20T, E35N, M36I, R41KT, K43Q, R57K, D60N, Q61D, I62V, L63P, I64L, V77I, L89I, I93LD
 RenG13236RenG13236KT744264PINAM46I, V82A, N88GSL33F, Q58EL10V, I13V, I15V, K20T, E35D, M36I, R41K, I62V, L63P, A71T, I72TD
 RenG12819RenG12819KT743847PINAI54V, V82S, L90ML33F, F53LQ7D, L10I, I13V, K20T, E34N, E35D, M36I, N37NT, R41K, I62V, L63AP, I64L, A71M, I72V, T74S, V77L, I93LD
 RenG12091RenG12091KT743119PINAM46I, I54V, V82A, L90MG73S, L89VL10V, I13V, K20T, L33L_L, M36I, R41K, K55R, I62IV, L63P, I64IL, A71V, I93L, N98ID
 RenG11672RenG11672KT742700PINAD30N, M46L, I54V, V82ACGS, L90ML33LF, F53L, N88DI15V, K20T, E35N, M36I, N37NT, R41K, Q61H, I62V, L63P, I64L, A71F, V77IL, I93LD
 RenG11284RenG11284KT742312PINAD30N, M46L, I54V, V82ACGS, L90ML33LF, F53L, N88DI15V, K20T, E35N, M36I, N37NT, R41K, Q61H, I62V, L63P, I64L, A71F, V77IL, I93LD
 RenG11503RenG11503KT742531PINAM46I, I50V, I54V, V82AK43T, F53LL10V, I15V, K20T, E35D, M36I, N37D, R41K, L63LP, I64V, A71V, V77ID
 RenG10591RenG10591KT741619PINAL90ML23I, F53LL10I, T12K, I13L, I15V, L19Q, K20T, E35D, M36I, N37NADT, R41K, K55R, R57K, I62V, L63P, I66IV, A71V, T74S, V75ID
 RenG11171RenG11171KT742199PINAI54V, L90M L10V, I15V, K20T, E35G, M36I, N37D, R41K, I62V, L63P, A71V, T74S, I85IV, I93LD
 RenG10029RenG10029KT741057PINAI50L I13V, K20T, E35D, M36I, R41K, K45KI, R57K, D60E, Q61D, L63P, E65D, V77I, L89MD
 RenG10437RenG10437KT741465PINAI54V, V82A, L90M L10V, T12E, I15V, L19I, K20T, E35N, M36I, R41K, I62V, L63P, I64M, A71V, T74S, I93LD
 RenG10051RenG10051KT741079PINAL90ML23I, F53L, G73SL10LI, K14KN, I15V, K20T, E34EQ, E35D, M36I, R41K, K45R, I62IV, L63P, I66IV, A71IL, I72T, V77I, I93LD