<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation K20M
Rx PI-naive
IncludeMixtures No
References 10
Patients 15
Isolates 15
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cuevas (2002)CU60CU60AF425441None   I13V, K14R, G16E, K20M, E35D, M36I, R41K, K43R, L63P, H69Q, L89MD
Gibb (2002)DMG8888_w-21 None   I13V, K14R, K20M, M36I, R41K, L63H, I64V, I72VD
Church (2008)391100H391100HEU380747None   I13V, K20M, E35D, M36I, R41K, I64V, H69QD
Nyombi (2008)TBK080TBK080EU251767None   I13V, K14KR, I15V, G16E, K20M, P39S, G40K, I62IV, L63LF, I64V, V82ID
Eshleman (2009)C10111W307-156980FJ389086None   I13V, K20M, M36I, R41K, I64V, H69YD
Towler (2010)450487-M450487-MHM037881None   I13V, K20M, M36I, P39S, R41K, I62V, L63P, I64VD
Hamers (2011)CP076301769CP076301769HQ993755None   I13V, K20M, E35N, M36I, R41K, R57RKQ, Q61DE, I62IV, L63E, I64V, E65ED, C67CW, K70KRD
 CP076300841CP076300841HQ994957None  L33II13V, K20M, E35D, M36I, R41K, L63Q, I64V, I72VD
 CP076301883CP076301883HQ995011None  L33IT12P, I13V, K20M, M36I, R41K, L63S, I64VD
 CP076302982CP076302982HQ995059None   Q7H, L10I, I13V, I15V, Q18H, K20M, M36I, N37D, R41K, L63T, I64V, E65D, K70RD
Sigaloff (2013)JCR047_0JCR047_0JX181988None   L10V, I13V, G16A, K20M, M36L, R41K, I64V, V75ID
 JCR022_0JCR022_0JX181985None   I13V, K20M, E35N, M36I, R41K, I64V, H69QD
Bartolo (2014)09AOHDP5409AOHDP54KF853865None  V11IL10I, I13V, I15V, G16E, K20M, E35D, M36I, R41K, R57K, L63T, G73D, L89FD
Lee (2014)AMU043AMU043KJ906663None   I13V, I15V, K20M, M36F, R41K, D60E, I62V, L63P, I64V, V75ID
 MBA1275MBA1275KJ906967None   T12A, I13V, K20M, M36I, R41K, L63Q, I64V, K70R, I72VD