<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation K20M
Rx PI-naive
IncludeMixtures No
References 14
Patients 25
Isolates 25
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG8888_w-21 None   I13V, K14R, K20M, M36I, R41K, L63H, I64V, I72VD
Church (2008)391100H391100HEU380747None   I13V, K20M, E35D, M36I, R41K, I64V, H69QD
Nyombi (2008)TBK080TBK080EU251767None   I13V, K14KR, I15V, G16E, K20M, P39S, G40K, I62IV, L63LF, I64V, V82ID
Eshleman (2009)C10111W307-156980FJ389086None   I13V, K20M, M36I, R41K, I64V, H69YD
Towler (2010)450487-M450487-MHM037881None   I13V, K20M, M36I, P39S, R41K, I62V, L63P, I64VD
Hamers (2011)CP076301769CP076301769HQ993755None   I13V, K20M, E35N, M36I, R41K, R57RKQ, Q61DE, I62IV, L63E, I64V, E65ED, C67CW, K70KRD
 CP076300841CP076300841HQ994957None  L33II13V, K20M, E35D, M36I, R41K, L63Q, I64V, I72VD
 CP076301883CP076301883HQ995011None  L33IT12P, I13V, K20M, M36I, R41K, L63S, I64VD
 CP076302982CP076302982HQ995059None   Q7H, L10I, I13V, I15V, Q18H, K20M, M36I, N37D, R41K, L63T, I64V, E65D, K70RD
Sigaloff (2013)JCR047_0JCR047_0JX181988None   P1L, L10V, I13V, G16A, K20M, M36L, R41K, I64V, V75ID
 JCR022_0JCR022_0JX181985None   I13V, K20M, E35N, M36I, R41K, I64V, H69QD
Lee (2014)AMU043AMU043KJ906663None   I13V, I15V, K20M, M36F, R41K, D60E, I62V, L63P, I64V, V75ID
 MBA1275MBA1275KJ906967None   T12A, I13V, K20M, M36I, R41K, L63Q, I64V, K70R, I72VD
Parczewski (2014)643_1643_1JQ305758None  L33LII13V, K20M, E35ED, M36IT, P39PQ, R41K, L63LP, I64V, K70RD
 A051_1A051_1KM284533None   I13V, K20M, E35D, M36I, R41K, R57K, D60E, L63P, I64V, I72ED
 258_1258_1JQ305751None   I13V, I15V, K20M, E35D, M36I, R41K, D60E, L63P, I72ED
Hora (2015)DEURF10UG007DEURF10UG007KF716489None   I13V, K20M, E35D, M36I, R41K, L63Q, I64V, E65DD
Kityo (2016)JFP115JFP115m0KT348098None   T12Q, I13V, K20M, M36I, N37T, R41K, D60E, Q61E, I64VD
 MBA056MBA056m0KT348153None   I13V, L19Q, K20M, E35S, M36I, N37D, R41K, I64V, I72VD
Otecko (2016)406813406813KX306407None   T12TA, I13IV, K14KR, I15V, K20M, E35D, M36I, R41K, L63T, I64V, H69HYD
Steegen (2016)GFWCB037GFWCB037KU128190None   I13V, K20M, E35N, M36I, N37D, R41K, L63Q, I64VD
Kityo (2017)JCR022JCR022m0KT347903None   I13V, K20M, E35N, M36I, R41K, I64V, H69QD
 JCR037JCR037m0KT347916None   I13V, K20M, E35D, M36I, R41K, D60E, I64VD
 JCR047JCR047m0KT347924None   L10V, I13V, G16A, K20M, M36L, R41K, I64V, V75ID
 JFP023JFP023m0KT348015None  L33IL10V, T12S, I13V, K20M, M36I, R41K, D60E, I64VD