<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation K20M
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 24
Isolates 25
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M39M39AY010402NFV M46I, I54V, V82A G16E, K20M, M36I, P39Q, R41K, L63R, I64VD
Cuevas (2002)CU95CU95AF425476IDV   I13V, I15V, K20M, M36I, R41K, L63P, I64L, H69QD
Monno (2003)ML_Pat89ML_Pat89 PINAI54IV, I84V, L90MG73TL10I, I15V, G16E, L19Q, K20M, I62V, L63N, A71V, I72T, P79D, I93LD
Gomez-Carrillo (2004)101028101028AY365623PINAI54V, L76V, V82A L10I, I13V, I15V, K20M, E35D, M36I, R41K, Q61N, L63P, A71V, I72T, L89I, I93LD
Snoeck (2004)BE40BE40AY900743SQV, IDV, NFV236L90M L10I, I15V, K20M, R41K, D60E, I62V, L63P, A71T, I72V, V75I, L89M, I93LD
Non-B Workgroup (2005)TK1024TK1024 IDV, NFV, RTV, LPV234  I13V, K20M, M36I, R41K, K45KR, L63P, I64V, H69HY, I72E, P79PAD
  TK1024a IDV, NFV, RTV, LPV277  I13V, K20M, M36I, R41K, I62IV, L63P, I64V, H69HY, I72E, P79XD
Baxter (2006)48-30563056-30318DQ877968PINAM46I, I54V, L76V, V82TL10F, L89VI13V, K20M, M36I, R41K, I62V, L63P, A71V, I72V, I93LD
El Annaz (2012)14881488.PRJN185238IDV52  L19Q, K20M, E35D, M36I, R41K, L63S, I64VD
Jones (2012)146099146099JN669672PINAL90LM L10V, I13V, K14R, K20M, E35D, M36I, N37D, R57RK, Q61N, L63P, A71T, I72TD
 159575159575JN669956PINAI54V, V82A L10V, I15V, G16GE, K20M, E35D, M36I, R41K, K45R, R57K, L63PS, A71TD
 170719170719JN670232PINAI54V, V82A, L90ML33IL10I, I13V, K14R, K20M, E35D, M36I, N37D, R41K, Q61N, L63P, A71T, I72TD
 175531175531JN670363PINAM46L, I54IV, V82AL24I, L33LFL10V, I15V, K20M, E35DN, M36I, N37D, R41K, K55KR, R57K, Q61D, A71V, I72TD
 183878183878JN670662PINA  L10V, G17E, K20M, E35D, M36I, R41K, D60E, Q61N, L63V, E65D, I72ITD
 188898188898JN670762PINAD30NN88DL10V, I13V, K14R, G16E, K20M, E35G, M36I, R41K, R57K, Q61N, L63SD
Kouri (2012)CU1270-09CU1270-09JQ585285PINA  I15V, G16E, K20M, P39S, R41K, K43R, Q61N, L63P, V77ID
Diaz (2015)RenG16766RenG16766KT747794PINAV32I, M46I, I54L, I84V, L90ML10F, V11I, L33F, G73T, L89VI13V, K20M, M36I, I62V, L63P, I66V, A71T, I72V, C95ID
 RenG17271RenG17271KT748299PINAM46L, G48Q, I54V, L76V, V82AL33I, F53LL10V, I13V, K14KR, L19V, K20M, M36I, D60E, Q61N, I62IV, L63P, T74S, L89I, T91SD
 RenG14273RenG14273KT745301PINAI50L, V82AL33F, K43KT, G73SL10V, I13V, I15V, K20M, E35G, M36I, R41K, K55KN, R57K, D60E, Q61N, I62V, L63P, A71AITV, I93LD
 RenG15235RenG15235KT746263PINAI54V, V82A, L90M L10V, I15IV, K20M, E35D, M36IV, R41K, R57K, Q61N, L63P, I64V, A71AV, T74S, I93LD
 RenG14846RenG14846KT745874PINAM46L, I54V, V82A, L90ML33FL10V, I15V, G16E, K20M, E35N, M36I, L38LF, R41K, K55R, R57K, Q61D, I62V, L63C, I64IL, E65ED, A71V, I72IT, T74S, T91A, I93LD
 RenG12299RenG12299KT743327PINAM46I, I54V, V82AL24I, L33F, F53L, T74PP9PR, L10I, T12TA, I13V, I15V, K20M, E35D, M36I, N37D, R41K, K45I, K55R, I62V, L63E, I64IV, E65D, L89MD
 RenG12131RenG12131KT743159PINA  L10V, I13V, K20M, E35D, M36I, N37S, P39T, R41K, R57K, Q61D, I64V, E65D, A71AV, I93ILD
 RenG10987RenG10987KT742015PINAL90M I15V, K20M, E35D, M36I, R41K, R57K, Q61N, L63P, V77VI, I93LD
 RenG11242RenG11242KT742270PINA  T12K, I15V, K20M, E35D, M36I, R41K, R57K, L63PD