<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation K20I
Rx PI-naive
IncludeMixtures No
References 18
Patients 27
Isolates 27
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Holguin (2000)AHHC18HolgHC19AF188350None   I13V, K14R, I15V, K20I, E35Q, M36I, R41K, R57K, I64M, C67E, H69K, V82I, I85M, L89MD
Cuevas (2002)CU57CU57AF425438None   I13V, L19I, K20I, E35D, M36I, R41K, H69K, V82I, L89MD
 CU45CU45AF425426None   L10I, I13V, K20I, E35D, M36I, R41K, K45R, L63P, H69Q, L89MD
Koizumi (2006)YK_04CM063YK_04CM063DQ461854None   I13V, K14R, K20I, M36I, R41K, H69K, L89MD
Delgado (2008)GH_046GH_046EU177919None   T12TA, I13V, K20I, M36I, R41K, Q61N, L63N, I64IMD
Eshleman (2009)A06734R908-102647FJ389138None   I13V, K20I, M36I, R41K, L63P, I64V, E65DD
Hawkins (2009)Q967ZZQ967FJ931372None   I13V, K14KR, K20I, M36I, R41K, L63A, I64LD
Vercauteren (2009)pt2185108155411GQ398839None   Q7R, L10LP, T12A, I13V, I15V, K20I, E35D, M36I, R41K, L63P, I64L, H69HDD
 pt16243615684334GQ399400None   I13V, I15IV, K20I, E35G, M36I, R41K, L63LP, V77ID
 pt13355226438876GQ399689None   I13V, K14R, K20I, E35D, M36I, R41K, L63P, I64LD
 pt7618593258083GQ400263None   T12TAEK, I13V, K14KR, I15V, K20I, E35ED, M36I, R41K, L63P, I64LD
 pt5959420845038GQ400429None   I13V, K14R, K20I, E35D, M36I, N37D, L63PD
Diop-Ndiaye (2010)1898HALD1898HALDFN599801None   T12K, I13V, K14R, K20I, M36I, R41K, Q61D, L63P, I64VD
Yang (2010)20106934362010693436JQ616878None   L10I, I13V, I15V, K20I, E35D, M36I, R41K, Q61H, K70R, A71T, I72ED
 20106934532010693453JQ616908None   L10I, I13V, I15V, K20I, E35D, M36I, R41K, H69L, K70R, A71T, I72ED
El Annaz (2011)76037603HQ393285None   I13V, K14KR, I15V, K20I, E35N, M36I, R41K, K45R, L63AD
Hamers (2011)CP076301798CP076301798HQ994975None  L33FI13V, K20I, M36I, R41K, I64V, E65DD
De Gascun (2012)IRL32980IRL32980JN622307None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
 IRL32981IRL32981JN622308None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
Ssemwanga (2012)6601HR6601HRJF800208None   I13V, K20I, M36I, P39T, R41K, I64V, T91AD
Frentz (2013)EHR-25464EHR-25464JX299982None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
 EHR-60237EHR-60237JX300541None   I13A, K14R, K20I, M36I, R41K, K43R, L63PD
 EHR-92753EHR-92753JX301085None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, H69Q, A71TD
Lunar (2013)13869-0813869-08JX046414None   I13V, K14KR, I15IV, K20I, M36I, R41K, K43R, L63PD
Temereanca (2013)SR6SR6JX966526None   L10I, T12K, I13V, I15V, K20I, E35D, M36I, R41K, R57K, L63T, E65D, I72V, T74S, L89MD
Lee (2014)MBA1294MBA1294KJ906984None   L10I, I13V, K14KR, G16GE, L19P, K20I, M36I, R41K, L63A, E65D, L89MD
Meixenberger (2014)11-0243211-02432KJ771545None   L10V, I13V, I15V, G16E, K20I, M36I, R41K, R57K, D60E, Q61E, I62V, L63S, I64V, A71V, P79D, I93LD