<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation K20I
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 10
Isolates 10
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Montes (2004)MB_patESTU01_ESTU702AJ577887SQV, RTV, NFV, IDV309M46I, I84V, L90MV11I, G73SL10V, I13V, K20I, L33V, I62V, L63PD
 MB_patRAM01_RAM707AJ577979Unknown, RTV, IDV>90M46L, G48V, I54V, V82T L10V, I13V, K20I, M36I, R41K, I66F, H69K, K70R, L89MD
Non-B Workgroup (2005)TK1014TK1014 RTV, SQV, NFV, IDV246M46I, I84IVL24LIL10LV, I13V, K20I, E35D, M36I, R41K, L63P, H69K, T74S, T80TA, V82X, L89IMD
Baxter (2006)12-22582258-30721DQ876701PINAI54V, V82AL10FI13V, G16E, K20I, E35D, M36I, P39S, R41K, K45A, R57KT, I62V, L63C, I64VD
 48-14321432-30818DQ877822PINAM46I, I54V, L76V, V82TL24IL10I, I13A, K20I, E35D, M36I, R41K, Q61H, L63P, H69K, T74S, L89ID
 48-14391439-30929DQ877829PINAM46I, I54V, L76LV, V82A, L90ML10FII13V, K20I, E34EK, M36I, R41K, I62V, L63P, I64IV, A71T, L89LI, I93LD
 48-50145014-30514DQ878549PINAM46I, I54V, V82A, L90LML10F, Q58EI13V, K20I, E35D, M36I, R41K, D60E, I62V, L63P, I64V, N83SD
 48-50525052-30515DQ878573PINAM46MI, G48M, I54V, V82A, L90MF53L, L89IVT4S, L10IV, I13V, K14R, G17DE, K20I, L33L_L, M36V, R41K, L63P, H69K, K70R, A71T, T74S, Q92KD
Koyalta (2009)68TCHAD-68FJ688199IDV26M46I, L76V T12P, I15V, L19V, K20I, E35N, M36I, N37D, R41K, R57K, D60E, I62V, L63P, I64V, K70R, I85VD
Jones (2012)159048159048JN669940PINAV32I, I47V, I54M, L90MV11VIL10I, T12K, I13IV, K20I, E21ED, E35N, M36I, R41K, R57K, Q61N, L63P, I64IV, T74S, V82I, I85VD

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