<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L10V
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 39
Isolates 39
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cuevas (2002)CU80CU80AF425461IDV   L10V, E35D, M36I, R41K, K43R, L63P, H69Q, V82ID
Montes (2004)MB_patESTU01_ESTU702AJ577887SQV, RTV, NFV, IDV309M46I, I84V, L90MV11I, G73SL10V, I13V, K20I, L33V, I62V, L63PD
Non-B Workgroup (2005)UK1392UK1392AY900799SQV161L90M L10V, I13V, R41K, L63P, I64V, K70R, I72IV, T74SD
 UK1557UK1557AY900679NFV, SQV104D30NN88DL10V, I13V, E35D, M36I, R41K, L63PD
 TK2014TK2014 SQV, RTV, IDV, NFV307M46L, I54V, V82A L10V, R41K, D60E, L63P, I66IF, A71V, T74S, V77ID
 TK3013TK3013 SQV, NFV205L90MG73SL10V, R41K, L63P, A71I, V77I, L89M, I93LD
 TK3037TK3037 RTV196I54V, V82A L10V, T12TA, I13V, K14R, G16A, R41K, K43R, I62V, L63P, A71TD
Rhee (2005)CA9792CA34173AY797858LPV79M46I, V82F, I84C L10V, I13V, K20T, R41K, L63P, I64VD
Baxter (2006)48-12121212-30812DQ877754PINAM46L, I54V, V82AL24I, L33FL10V, I15V, E35D, M36I, N37ND, R41K, I62V, L63PD
 48-22442244-30722DQ877883PINAV32I, M46I, I54V, V82A, L90MK43T, G73TL10V, I15V, K20R, M36I, R41N, K55R, D60E, L63P, H69HR, K70R, A71V, I93L, C95VD
 48-30833083-30313DQ877992PINAV32I, M46I, I47V, I54V, V82A, L90MK43T, F53L, G73S, L89VL10V, T12I, I13V, G16A, K20I, M36I, K55R, L63P, A71VD
 48-60286028-30409DQ878627PINAI54V, V82F, L90MV11VI, L33LF, F53LL10V, I13IV, R41K, K45V, I62V, L63P, H69K, A71V, I72V, T74A, V77ID
 48-71027102-40225DQ878956PI, RTV, TPV>30M46I, I47A, I84V L10V, I13V, K20T, L33V, M36I, N37C, R57K, L63P, I64VD
Laurent (2006)CK2-9802CM-98AM279450IDV30  L10V, I15V, E35D, M36I, R41K, L63P, H69QD
von Wyl (2007)2410516511EF449876RTV, PINA  L10V, I13V, E35D, M36I, R41K, I62V, L63H, I64VD
Waleria-Aleixo (2008)08PR06072008PR060720FJ591542PINAI54V, V82TL24I, F53LL10V, I13V, K20R, E35D, M36V, N37T, R41K, R57K, I62V, L63P, I64V, A71V, T74SD
 08RJ06047108RJ060471FJ591665PINA  L10V, I13V, E35D, M36I, R41K, L63PD
 08PR06075308PR060753FJ591549PINAV32I, M46MI, I54V, L90ML33I, K43T, F53LL10V, I13V, G16E, L19LI, K20M, E35EG, M36I, L63R, I66F, H69R, A71V, I72IVD
 08PR05023208PR050232FJ591261PINAI54L, V82A, L90ML33F, K43T, F53LL10V, I13V, I15IV, K20R, E35D, M36I, R41K, I62V, L63P, H69K, A71I, T74S, I93IMD
Kouri (2012)CU117-10CU117-10JQ585366PINA  L10V, I15IV, E35D, M36I, R41K, L63P, H69Q, I72VD
 CU25-10CU25-10JQ585358PINAM46L, I54V, V82A, L90ML33F, K43T, F53L, G73SL10V, I13V, L19LI, K20R, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71I, I93LD
 CU163-10CU163-10JQ585454PINA  Q2H, L10V, I13V, E35D, M36I, R41K, K45R, R57K, D60E, L63P, H69Q, V77ID
 CU1708-09CU1708-09JQ585308PINA  L10V, E21K, E35D, M36I, R41K, K43R, I62V, L63P, H69Q, A71T, I72IT, I93LD
Reynolds (2012)G0715G0715-2JN652208LPV   L10V, I13V, R41K, R57K, I64V, T74S, V77ID
Alcantara (2013)BRGO4151BRGO4151JN662432LPV   L10V, I13V, G16E, M36I, R41K, L63TD
Van Zyl (2013)O4782100KC423617LPV156M46I, I54V, L76LV, V82AQ58EL10V, T12P, I13V, G16GE, K20R, M36I, R41K, Q61QR, I64V, P79PHD
 364111.ZA.GT1597KC423388LPV   L10V, G16E, M36I, N37Q, R41K, D60E, L63T, H69K, I72V, I93LD
Diaz (2015)RenG16432RenG16432KT747460PINAI50L, N88SQ58EL10V, G16E, K20R, E35D, M36I, N37T, L63T, E65ED, H69K, A71V, I72T, L89M, I93LD
 RenG16359RenG16359KT747387PINA  L10V, T12I, E35D, M36I, R41K, I62VD
 RenG15230RenG15230KT746258PINA  L10V, I13V, K20KT, M36I, N37D, L63LP, I64IVD
 RenG15170RenG15170KT746198PINA G73STL10V, T12S, I15V, K20T, E35D, M36I, N37DE, R41K, K43KR, I62V, L63P, T74S, I93LD
 RenG12525RenG12525KT743553PINA  L10V, I15V, M36I, R41K, K55KRD
 RenG12305RenG12305KT743333PINAM46L, I54V, V82AL24I, L33F, K43TL10V, I15V, K20R, E35D, M36I, R41K, I62V, L63PD
 RenG13355RenG13355KT744383PINAV32I, M46I, I47V, I50L, I54V, V82AL23IL10V, I15V, K20R, E35D, M36I, N37S, R41RK, K43I, K55R, R57K, L63PD
 RenG13236RenG13236KT744264PINAM46I, V82A, N88GSL33F, Q58EL10V, I13V, I15V, K20T, E35D, M36I, R41K, I62V, L63P, A71T, I72TD
 RenG12091RenG12091KT743119PINAM46I, I54V, V82A, L90MG73S, L89VL10V, I13V, K20T, L33L_L, M36I, R41K, K55R, I62IV, L63P, I64IL, A71V, I93L, N98ID
 RenG11659RenG11659KT742687PINAM46L, V82AL24I, Q58EL10V, I15V, L19I, K20R, M36I, R41K, L63P, I64L, H69K, I72V, L89MD
 RenG11099RenG11099KT742127PINAM46L, I54V, L76V, V82A, L90M L10V, I15V, K20R, M36I, N37D, R41K, I62V, L63P, I64V, H69R, A71V, I72V, I85V, I93LD
 RenG10814RenG10814KT741842PINA  L10V, T12A, I13V, K14R, M36I, R41K, Q61N, L63P, L89MD