<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L10V
Rx >= 1 PI
IncludeMixtures No
References 14
Patients 61
Isolates 61
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Cuevas (2002)CU80CU80AF425461IDV   L10V, E35D, M36I, R41K, K43R, L63P, H69Q, V82ID
Gomez-Carrillo (2004)118423118423AY365949PINAL90M L10V, I13V, K14R, K20T, E35D, M36I, N37D, R41K, Q61N, L63P, A71T, I72T, T74SD
Montes (2004)MB_patESTU01_ESTU702AJ577887SQV, RTV, NFV, IDV309M46I, I84V, L90MV11I, G73SL10V, I13V, K20I, L33V, I62V, L63PD
 MB_patRAM01_RAM707AJ577979Unknown, RTV, IDV>90M46L, G48V, I54V, V82T L10V, I13V, K20I, M36I, R41K, I66F, H69K, K70R, L89MD
Non-B Workgroup (2005)UK1392UK1392AY900799SQV161L90M L10V, I13V, R41K, L63P, I64V, K70R, I72IV, T74SD
 UK1557UK1557AY900679NFV, SQV104D30NN88DL10V, I13V, E35D, M36I, R41K, L63PD
 TK2014TK2014 SQV, RTV, IDV, NFV307M46L, I54V, V82A L10V, R41K, D60E, L63P, I66IF, A71V, T74S, V77ID
 TK3037TK3037 RTV196I54V, V82A L10V, T12TA, I13V, K14R, G16A, R41K, K43R, I62V, L63P, A71TD
Baxter (2006)48-12121212-30812DQ877754PINAM46L, I54V, V82AL24I, L33FL10V, I15V, E35D, M36I, N37ND, R41K, I62V, L63PD
 48-22442244-30722DQ877883PINAV32I, M46I, I54V, V82A, L90MK43T, G73TL10V, I15V, K20R, M36I, R41N, K55R, D60E, L63P, H69HR, K70R, A71V, I93L, C95VD
 48-33733373-30620DQ878231PINAM46L, G48V, I54V, V82A L10V, I15V, L19I, R41K, I62V, L63S, I64L, V77ID
Laurent (2006)CK2-9802CM-98AM279450IDV30  L10V, I15V, E35D, M36I, R41K, L63P, H69QD
von Wyl (2007)2410516511EF449876RTV, PINA  L10V, I13V, E35D, M36I, R41K, I62V, L63H, I64VD
 310371422EF449968RTV, PINAM46I, I54V, L76V, V82ML24I, L33FL10V, I13V, K20R, E35D, M36I, N37DE, K55R, R57K, D60E, I62V, L63P, V75I, L89M, T91SD
Cardoso (2009)3117BRGO3117FJ638454PINAM46I, I54V, L76V, V82A, L90ML33FL10V, I13V, I15V, K20R, E35D, M36I, K55R, R57K, D60E, I62V, L63P, A71V, I72V, I93LD
Dau (2010)07823A07823AGU581871PINAM46I, L90M L10V, I13V, N37A, K55R, R57K, I62V, L63P, I64IV, I72IT, T74S, V77I, L89LM, I93LD
Aulicino (2011)ARL636VSQARL636VSQFJ525813PINAM46I, I47V, I54V, V82AL24I, L33F, K43T, F53L, Q58EL10V, G16A, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61D, I62V, L63P, A71V, I93LD
 ARM856HJMARM856HJMFJ525843PINAD30N, M46L, I54V, L90MN88DL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, I62V, L63P, A71T, I72V, I93LD
 ARN394FGLARN394FGLFJ525858PINAI54V, V82A, L90M L10V, K20R, E35D, M36I, N37D, R41K, R57K, Q61D, I62V, L63V, A71V, I72V, T74SD
 ARN571EAEARN571EAEFJ525863PINA  L10V, I13V, K14N, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, E65D, A71T, T74S, Q92KD
 4624-N636GLL4624-N636GLLHQ158181PINA  L10V, I15V, G17D, Q18H, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, L63V, E65D, I72VD
 4777-O319TTL4777-O319TTLHQ158189PINA  L10V, T12M, I15V, M36I, R41K, Q61N, G73RD
Jones (2012)146099146099JN669672PINAL90LM L10V, I13V, K14R, K20M, E35D, M36I, N37D, R57RK, Q61N, L63P, A71T, I72TD
 147603147603JN669694PINA  L10V, I15IV, G16E, M36I, R41K, K43R, R57K, Q61N, L63C, I93L, T96TAD
 156350156350JN669863PINA  L10V, K20KR, E35D, M36I, R41K, R57K, Q61N, L63Q, P79D, I93LD
 159279159279JN669946PINAI47V, I54V, V82A, L90ML33F, G48W, F53L, Q58EL10V, I13V, G16E, K20R, E35D, M36I, R41K, R57K, Q61N, L63C, C67E, A71V, I93LD
 159280159280JN669947PINA  L10V, T12I, E35D, M36I, R41K, R57K, Q61N, I72M, V77ID
 159575159575JN669956PINAI54V, V82A L10V, I15V, G16GE, K20M, E35D, M36I, R41K, K45R, R57K, L63PS, A71TD
 159787159787JN669960PINAI54V L10V, I13V, K20R, E35D, M36I, R41K, R57K, Q61N, I64IV, A71V, I72T, T74S, Q92R, I93LD
 162069162069JN670025PINAL90M L10V, I13V, I15V, K20T, E35D, M36I, R41K, R57K, D60E, Q61D, L63P, A71V, T74S, I93LD
 163678163678JN670068PINAL90LM L10V, I13V, I15V, K20T, E35D, M36I, R41K, K43R, R57K, Q61N, L63T, I64L, I72T, T74S, I93LD
 166308166308JN670124PINAM46I, I54V, V82TL33F, L76IL10V, T12Q, I13V, I15V, L19I, K20KR, E35D, M36IL, R41K, K55R, R57K, Q61N, L63P, I64V, A71V, T74SD
 169815169815JN670212PINA  L10V, T12S, I15V, E35D, M36I, R41K, R57K, D60E, Q61D, L63AD
 171752171752JN670267PINAD30NN88DL10V, I13V, I15IV, E35D, M36I, N37D, R41K, K45R, R57K, Q61N, L63P, V75I, I93LD
 171784171784JN670271PINAI54IV, V82A, L90ML33LFL10V, I13V, K20KR, E35D, M36I, R41K, R57K, Q61D, I62V, L63PT, A71V, I72T, T74S, I93LD
 172862172862JN670305PINAM46L, I54V, V82A, L90ML33FL10V, K20R, E35D, M36I, N37D, R41K, R57K, Q61N, I62IV, L63P, I64L, A71V, Q92K, I93LD
 173626173626JN670339PINAI54V, V82T, N88S L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71IV, I93LD
 175531175531JN670363PINAM46L, I54IV, V82AL24I, L33LFL10V, I15V, K20M, E35DN, M36I, N37D, R41K, K55KR, R57K, Q61D, A71V, I72TD
 176581176581JN670402PINA  L10V, M36I, N37S, R41K, L63P, I64V, I93LD
 177131177131JN670427PINA  L10V, T12A, I13V, K14R, G16GE, E35D, M36I, R41K, Q61D, L63T, I64V, I72TD
 177590177590JN670450PINAD30NN88DL10V, I13V, I15V, K20R, E35D, M36I, R41K, Q61D, L63P, V75I, I93LD
 178114178114JN670471PINAI54V, V82A, L90M L10V, K20R, M36I, R41K, R57K, Q61N, L63A, A71V, T74S, I93LD
 179876179876JN670531PINA  L10V, E35D, M36I, R41K, R57K, Q61D, L63P, I93LD
 182041182041JN670597PINAL90M L10V, I13V, K20T, E35D, M36I, R41K, R57K, Q61N, L63P, T74S, I93LD
 183878183878JN670662PINA  L10V, G17E, K20M, E35D, M36I, R41K, D60E, Q61N, L63V, E65D, I72ITD
 183927183927JN670665PINAL90M L10V, I13V, K20R, E35D, M36I, N37D, R41K, R57K, Q61DN, I64V, I72T, I93LD
 187807187807JN670741PINAM46L, I54V, V82A, L90ML33F, K43T, G73SQ7QH, L10V, I13V, K20R, E35D, M36I, L38LS, R41K, I62V, L63P, H69R, A71T, I72T, V77ID
 188898188898JN670762PINAD30NN88DL10V, I13V, K14R, G16E, K20M, E35G, M36I, R41K, R57K, Q61N, L63SD
 189796189796JN670781PINAI54V, L90ML23LIL10V, I13V, I15V, L19LV, K20T, E35D, M36I, N37D, R41RK, R57K, D60E, Q61D, I62V, L63P, A71I, T74S, I93LD
 189993189993JN670786PINA  L10V, I13V, G16GE, K20R, M36I, R41K, R57K, Q61ND
 194683194683JN670947PINAM46I, I54V, L76V, V82A, L90M L10V, I15V, K20R, E35D, M36I, R41K, R57K, Q61N, L63P, A71V, I72T, I93LD
 195598195598JN670988PINAM46I, V82A L10V, E35D, M36I, R41K, R57K, Q61D, L63T, E65D, I72T, V77ID
 195946195946JN671004PINAI54V, V82A L10V, I15V, K20R, E35D, M36I, N37D, R41K, Q61D, L63P, I93LD
 196487196487JN671026PINAM46I, I54V, L76V, V82AQ58EL10V, I15V, L19LI, K20R, M36I, R41K, D60DE, I62V, L63LP, I64IV, L89MD
 197920197920JN671095PINA  L10V, I15V, M36T, N37H, R57K, Q61D, I64VD
 200723200723JN671206PINA  L10V, E35D, M36I, R41K, R57K, D60E, Q61D, L63AD
 202598202598JN671278PINAL90M L10V, I15V, K20T, E35D, M36I, N37ND, R41K, R57K, Q61D, L63P, I72T, I93LD
 202646202646JN671284PINAI54L, L90ML33FL10V, I13V, I15V, K20T, E35D, M36I, R41K, R57K, Q61N, I62V, L63H, T74S, Q92QKD
Reynolds (2012)G0715G0715-2JN652208LPV   L10V, I13V, R41K, R57K, I64V, T74S, V77ID
Van Zyl (2013)4782100KC423617LPV156M46I, I54V, L76LV, V82AQ58EL10V, T12P, I13V, G16GE, K20R, M36I, R41K, Q61QR, I64V, P79PHD
Grossman (2014)13831383KC213556LPV52  L10V, I13V, M36I, D60E, I62V, L63Q, I64V, E65DD