<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype D
Gene PR
Mutation L10F
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 16
Isolates 16
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Baxter (2006)12-11341134-30326DQ876024PINAV32I, M46I, I47V, I54M, I84V, L90ML10F, L33F, L89VI13V, I15V, K20T, M36I, N37S, R41K, L63P, A71V, G73D, I93LD
 12-14811481-30812DQ876616PINAD30N, I54V, L90ML10F, N88DE35D, M36I, N37S, R41K, I62V, L63P, A71T, I72M, I93LD
 12-22582258-30721DQ876701PINAI54V, V82AL10FI13V, G16E, K20I, E35D, M36I, P39S, R41K, K45A, R57KT, I62V, L63C, I64VD
 12-30773077-30403DQ877151PINAD30NL10F, N88DI13V, K14R, E35D, M36I, R41K, I62IV, L63Q, I64VD
 48-30563056-30318DQ877968PINAM46I, I54V, L76V, V82TL10F, L89VI13V, K20M, M36I, R41K, I62V, L63P, A71V, I72V, I93LD
 48-40244024-30630DQ878258PINAV32I, M46I, I47V, I54L, I84V, L90ML10F, V11I, L33F, L89VK14R, I15V, K20V, E35H, M36IL, R41K, L63P, C67CY, A71I, I85V, Q92KD
 48-50145014-30514DQ878549PINAM46I, I54V, V82A, L90LML10F, Q58EI13V, K20I, E35D, M36I, R41K, D60E, I62V, L63P, I64V, N83SD
 48-80168016-30826DQ879061PINAM46L, I54LL10F, Q58EI13V, K20T, E35ED, M36I, N37ND, R41K, L63Q, I64VD
Laurent (2006)CK2-8402CM-84AM279448NFV105 L10F, L33I, N88GI13V, E35D, M36I, N37E, R41K, V56A, I62V, L63P, H69Y, A71T, I72TD
Waleria-Aleixo (2008)08RJ06060708RJ060607FJ591767PINAM46I, I54V, I84V, L90ML10F, L33F, T74PK20I, E35N, M36I, N37DE, I62V, L63P, I64M, C67F, H69K, A71V, I72V, T91TS, Q92KD
Kouri (2012)CU1373-09CU1373-09JQ585294PINAV32I, M46L, L76V, V82AL10F, L33F, L89VI13V, K20R, M36I, N37D, R41K, K43R, Q61N, L63P, A71V, Q92KD
 CU90-10CU90-10JQ585361PINAI50V, I54L, L90ML10F, L33F, K43T, F53L, L89VQ2P, L5F, I13V, I15V, Q18L, L19I, K20T, E35D, M36I, N37G, R41K, D60E, L63P, H69HY, A71IV, V77I, V82I, I93ILD
 CU1209-09CU1209-09JQ585279PINAM46L, I54M, V82AL10F, L24I, L33F, Q58EI13V, K20R, M36I, R41K, K43KR, I62V, L63P, E65ED, A71VD
Diaz (2015)RenG15645RenG15645KT746673PINAM46I, I54V, I84V, L90ML10F, F53L, T74PI13V, K20R, E35D, M36I, R41K, K55H, R57K, L63P, H69R, A71V, L89I, T91S, Q92KD
 RenG10884RenG10884KT741912PINAD30N, I54V, V82A, L90ML10F, L33F, F53L, N88DI13V, I15V, G17D, L19I, K20T, E35N, M36I, N37E, R41T, K45V, D60E, Q61N, L63P, K70R, V77I, L89FD
 RenG11511RenG11511KT742539PINAI54V, V82AL10F, N88DT12K, I15V, L19I, K20T, E35D, M36I, N37EK, R41N, R57RK, D60E, L63P, A71VD