<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation L90M
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 24
Isolates 26
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Si-Mohamed (2000)AS_FANAS_FANAF199275IDV I84V, L90ML89VL10I, I13V, L19P, K20I, M36I, N37S, R41K, L63P, H69K, K70R, A71V, I72MCRF02_AG
Yahi (2001)NY_M31M31AY010395NFV L90M I13V, K14R, I15V, K20T, E35D, M36I, R41K, K45KR, H69K, L89IMCRF02_AG
Montes (2004)MB_patALC02_ALC723AJ577727NFV, SQV, RTV91I84V, L90M L10I, I13V, K20I, E35D, M36I, R41K, K43R, L63P, H69K, A71V, L89ICRF02_AG
 MB_patKES01_KES716AJ577920NFV136M46I, L90ML89VL10V, I13V, K14R, G16E, K20I, E35D, M36I, R41K, H69K, K70R, T74S, V75ICRF02_AG
Non-B Workgroup (2005)PL1692558358AY900968NFV M46I, L90ML89VL10V, I13V, K20V, M36I, R41K, L63P, H69K, K70RCRF02_AG
  71340 NFV, UnknownNAM46I, I84V, L90ML33LI, L89VL10V, I13A, K14KR, K20IV, A22AV, E35EG, M36I, R41RK, K55KR, L63P, I66FV, H69K, K70R, P79PACRF02_AG
 PL3560858508AY900971IDV, NFV M46I, I54V, V82A, L90M I13V, K14KR, I15V, L19V, K20I, E35D, M36I, I64M, H69K, L89MCRF02_AG
 PL3515957564AY901074IDV, NFV160M46I, I54V, I84IV, L90ML89VI13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, A71TCRF02_AG
 PL3568567040AY901084NFV21M46ML, I54IV, L90ML89MVI13AV, K14R, K20I, E35D, M36I, N37ND, R41K, I64X, H69K, A71AV, T74TSCRF02_AG
 PL2828567988AY901085IDV, ATV I84V, L90ML33LF, L89VL10V, I13V, K14R, G16E, K20IM, E35EG, M36I, R41K, Q61H, C67Y, G68D, H69K, A71T, I72RCRF02_AG
  65163 IDV, ATV, UnknownNAV82VA, I84IV, L90ML33F, K43KT, L89VL10V, I13V, K14R, G16E, K20IM, E35G, M36I, R41K, Q61H, C67Y, G68GE, H69Q, I72RCRF02_AG
 PL3692269089AY901091NFV87L90M L10V, T12S, I13V, K14R, G16E, K20I, E35G, M36I, P39S, R41K, I62IV, I66F, H69K, K70R, L89MCRF02_AG
 PL3504797181 IDV, NFV337M46I, L90ML89VL10V, I13V, K14KR, L19LP, K20I, E35G, M36I, N37E, R41K, I62V, H69K, K70R, T74SCRF02_AG
 PL3890100322 NFV61L90M I13V, K14R, G16E, K20IV, E35A, M36I, P39PS, R41K, H69K, L89ICRF02_AG
 PL53161101108 NFV52I54V, L90M I13V, G16E, K20I, E35D, M36I, R41K, I66F, H69K, K70R, L89MCRF02_AG
Baxter (2006)48-30363036-30310DQ877947PINAM46L, I54V, I84V, L90ML33I, L89VL10I, T12A, I13A, L19P, K20V, A22V, M36I, R41K, I66F, H69K, K70R, A71V, Q92KCRF02_AG
Seyler (2007)282CS_282 NFV, IDV150L90ML89VL10V, T12TK, I13V, L19P, K20I, E35G, M36I, N37ND, Y59YC, L63P, E65EK, H69K, K70R, A71TCRF02_AG
von Wyl (2007)1205327019EF449829PINAL90M L10V, I13V, K14R, I15V, K20I, E35G, M36I, R41K, L63P, G68E, H69R, A71T, L89ICRF02_AG
 291845355EF449895PINAL90M I13V, K14R, L19P, K20I, M36I, R41K, H69K, L89ICRF02_AG
Rosen-Zvi (2008)4600p46-1 RTV, SQV, NFV, APV141M46MIL, I54V, V82M, I84V, L90ML33F, Q58EL10V, T12V, I13IV, K14KR, I15V, K20R, E35D, M36I, N37E, R41K, R57K, L63P, H69K, L89ICRF02_AG
Kouri (2012)CU1163-09CU1163-09JQ585277PINAM46ML, L90M I13V, G16E, K20I, E35N, M36IR, R41K, H69K, K70KR, L89MCRF02_AG
 CU785-09CU785-09JQ585264PINAI54V, L90M I13V, K14R, G16E, K20I, E35D, M36I, N37K, P39S, R41K, I62V, H69K, A71V, I72V, T74S, L89ICRF02_AG
Nii-Trebi (2013)KF307KF307AB751493NFV L90M I13V, K14R, G16E, K20I, E35N, M36I, P39S, R41K, I64IV, H69K, K70KR, V82I, L89MCRF02_AG
Rawizza (2013)PJ2149PJ2149KF241459LPV M46LV, I54V, L76V, V82M, L90ML89IVT4S, L10IV, I13A, K20IV, A22V, E35D, M36I, N37DE, Q61E, I62V, L63P, C67F, H69K, A71I, I72L, P79A, T91S, Q92QKCRF02_AG
Thiam (2013)495-HALD495-HALDJN673647LPV M46I, I47V, I54V, I84V, L90ML33I, L89VT4S, L10I, T12M, I13A, K14M, L19P, K20I, A22V, E35D, M36I, N37D, R41RK, R57K, Q61QH, I62IV, L63P, I66F, H69K, A71VCRF02_AG
Nerrienet (2014)U0302042U0302042JN675764LPV M46I, I54V, V82A, L90ML10F, L33I, K43T, N88DV11L, I13V, L19LV, K20V, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71V, T74S, L89T, T91ACRF02_AG