<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation L89V
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 26
Isolates 29
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Si-Mohamed (2000)AS_FANAS_FANAF199275IDV I84V, L90ML89VL10I, I13V, L19P, K20I, M36I, N37S, R41K, L63P, H69K, K70R, A71V, I72MCRF02_AG
Yahi (2001)NY_M15M15AY010377PINA L89VL10V, I13V, K14R, L19P, K20I, E35N, M36I, N37D, R41K, H69K, T74SCRF02_AG
 NY_M65M65AY010428PINA L89VL10V, I13V, K14R, L19LP, K20I, E35N, M36I, N37D, R41K, H69K, T74SCRF02_AG
Snoeck (2002)BE2BE2AF338979IDV, SQV, RTV, NFV109V32I, I47V, G48V, I54V, V82ATF53FL, L89VL10V, I13V, L19IT, K20I, M36I, R41K, K55H, L63P, C67S, H69R, A71IVCRF02_AG
Vergne (2003)VL98SN65HALD00SN65AJ583751IDV  L89VL10V, I13V, L19P, K20I, M36I, R41K, H69K, K70RCRF02_AG
Montes (2004)MB_patKES01_KES716AJ577920NFV136M46I, L90ML89VL10V, I13V, K14R, G16E, K20I, E35D, M36I, R41K, H69K, K70R, T74S, V75ICRF02_AG
Non-B Workgroup (2005)PL3508557393AY900720IDV47M46MI, I84VL89VI13AV, K14R, K20I, M36I, R41K, I66F, H69K, A71ATCRF02_AG
 PL1692558358AY900968NFV M46I, L90ML89VL10V, I13V, K20V, M36I, R41K, L63P, H69K, K70RCRF02_AG
  71340 NFV, UnknownNAM46I, I84V, L90ML33LI, L89VL10V, I13A, K14KR, K20IV, A22AV, E35EG, M36I, R41RK, K55KR, L63P, I66FV, H69K, K70R, P79PACRF02_AG
 PL3515957564AY901074IDV, NFV160M46I, I54V, I84IV, L90ML89VI13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, A71TCRF02_AG
 PL2828567988AY901085IDV, ATV I84V, L90ML33LF, L89VL10V, I13V, K14R, G16E, K20IM, E35EG, M36I, R41K, Q61H, C67Y, G68D, H69K, A71T, I72RCRF02_AG
  65163 IDV, ATV, UnknownNAV82VA, I84IV, L90ML33F, K43KT, L89VL10V, I13V, K14R, G16E, K20IM, E35G, M36I, R41K, Q61H, C67Y, G68GE, H69Q, I72RCRF02_AG
 PL3504797181 IDV, NFV337M46I, L90ML89VL10V, I13V, K14KR, L19LP, K20I, E35G, M36I, N37E, R41K, I62V, H69K, K70R, T74SCRF02_AG
Baxter (2006)12-31973197-30821DQ876738PINAI54V, V82AL89VL10V, I13A, K14R, K20I, A22V, M36I, R41K, I62V, H69K, G73D, T74S, T91TSCRF02_AG
  3197-40128DQ876116PI, RTV, TPV>23I54V, V82AL89VL10V, I13A, K14R, K20I, A22V, L33L_L, M36I, R41K, I62V, H69K, G73D, T74S, T91TSCRF02_AG
 48-12261226-30417DQ877758PINAM46I, I47V, L76V, I84AV11I, G73S, L89VL10M, I13V, K14R, I15V, Q18I, K20I, M36I, N37D, R41K, H69K, A71V, T74SCRF02_AG
 48-30363036-30310DQ877947PINAM46L, I54V, I84V, L90ML33I, L89VL10I, T12A, I13A, L19P, K20V, A22V, M36I, R41K, I66F, H69K, K70R, A71V, Q92KCRF02_AG
 48-32833283-30916DQ878190PINAM46I, I54M, L76V, I84VG73A, L89VL10I, I13A, K14KR, L19LI, K20I, L33V, M36I, R41K, K55R, R57RK, D60E, L63P, I66F, H69KCRF02_AG
Seyler (2007)282CS_282 NFV, IDV150L90ML89VL10V, T12TK, I13V, L19P, K20I, E35G, M36I, N37ND, Y59YC, L63P, E65EK, H69K, K70R, A71TCRF02_AG
 545CS_545 IDV170I84VL33I, L89VL10I, I13V, K14R, L19P, K20I, A22V, M36I, N37D, L38I, R41K, L63P, H69K, A71V, T74SCRF02_AG
Charpentier (2011)2CP 001-032 Unknown, LPVNA L89VL10V, I13V, I15V, L19KR, K20I, E35G, M36I, N37ND, R41K, I62IV, L63P, H69K, K70N, A71T, T74TSCRF02_AG
Charpentier (2011)CR-24CR-24FJ688230PINAM46I, N88NSL89VI13V, K14R, K20I, M36I, P39S, R41K, I62V, L63P, H69K, A71TCRF02_AG
 CR-17CR-17FJ688223PINAM46LL89VT4TP, L10V, I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63P, I64M, I66F, H69K, K70R, A71T, I72VCRF02_AG
Kouri (2012)CU294-10CU294-10JQ585376PINAM46L, I54V, I84VQ58E, L89VI13A, L19P, K20I, A22V, L33V, E35D, M36I, N37D, I62IV, L63P, I66F, H69K, A71V, T74A, Q92K, I93IVCRF02_AG
 CU1213-09CU1213-09JQ585280PINAV32I, M46I, I47V, I54L, I84VL33F, F53L, Q58E, L89VL10I, T12E, I13AV, K14R, I15V, G16Q, K20V, E35G, M36I, P39S, R41RK, D60DN, I64V, I66F, H69K, K70E, A71V, I93IVCRF02_AG
Rawizza (2013)PJ9681PJ9681KF241511LPV I54V, V82AL89VL10V, I13A, K14R, I15V, K20I, A22V, E35D, M36I, R41K, Q61H, L63P, H69KCRF02_AG
 LN8580LN8580KF241492LPV M46I, I54V, L76V, V82VA, I84IVL89VL10LI, I13V, G16A, K20I, M36I, R41K, H69K, K70R, A71AVCRF02_AG
 LL3779LL3779KF241464LPV G48V, I54V, V82TL89VI13V, K14R, K20I, M36I, R41K, H69K, A71VCRF02_AG
Thiam (2013)495-HALD495-HALDJN673647LPV M46I, I47V, I54V, I84V, L90ML33I, L89VT4S, L10I, T12M, I13A, K14M, L19P, K20I, A22V, E35D, M36I, N37D, R41RK, R57K, Q61QH, I62IV, L63P, I66F, H69K, A71VCRF02_AG