<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation I84V
Rx >= 1 PI
IncludeMixtures No
References 11
Patients 31
Isolates 32
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Si-Mohamed (2000)AS_FANAS_FANAF199275IDV I84V, L90ML89VL10I, I13V, L19P, K20I, M36I, N37S, R41K, L63P, H69K, K70R, A71V, I72MCRF02_AG
Thomson (2001)MT-X230MT-X230AY017453IDV I84V I13V, K14R, K20I, M36I, N37D, R41K, I66F, H69K, L89MCRF02_AG
Montes (2004)MB_patALC02_ALC723AJ577727NFV, SQV, RTV91I84V, L90M L10I, I13V, K20I, E35D, M36I, R41K, K43R, L63P, H69K, A71V, L89ICRF02_AG
 MB_patFEU02_FEU726AJ577889IDV, SQV, RTV190I84V L10V, I13V, K14R, L19P, K20I, E21D, L33V, M36I, N37D, R41K, F53Y, I64L, H69K, K70R, T74S, L89MCRF02_AG
Non-B Workgroup (2005)PL3508557393AY900720IDV47M46MI, I84VL89VI13AV, K14R, K20I, M36I, R41K, I66F, H69K, A71ATCRF02_AG
 PL1692571340 NFV, UnknownNAM46I, I84V, L90ML33LI, L89VL10V, I13A, K14KR, K20IV, A22AV, E35EG, M36I, R41RK, K55KR, L63P, I66FV, H69K, K70R, P79PACRF02_AG
 PL2828567988AY901085IDV, ATV I84V, L90ML33LF, L89VL10V, I13V, K14R, G16E, K20IM, E35EG, M36I, R41K, Q61H, C67Y, G68D, H69K, A71T, I72RCRF02_AG
Baxter (2006)48-12441244-30527DQ877767PINAM46L, I54V, V82A, I84VV11VI, L33F, K43T, F53LT4A, L10V, I13V, G16A, L19P, K20M, E21A, E35D, M36L, K55R, Q61H, L63P, H69K, T74AS, L89I, T91SCRF02_AG
 48-30363036-30310DQ877947PINAM46L, I54V, I84V, L90ML33I, L89VL10I, T12A, I13A, L19P, K20V, A22V, M36I, R41K, I66F, H69K, K70R, A71V, Q92KCRF02_AG
 48-30903090-30925DQ877999PINAM46I, I47V, I54V, V82C, I84VV11I, L33I, K43T, F53FLL10I, T12M, I13V, K14R, L19P, K20I, A22V, M36I, R41K, K55R, H69K, K70R, I72V, T74S, L89I, T91SCRF02_AG
 48-32243224-30624DQ878131PINAM46I, I47IV, L76V, I84VL33LI, Q58EL10I, I13A, K20I, A22V, M36I, R41K, L63P, I66F, H69K, K70R, L89I, T91SCRF02_AG
 48-32833283-30916DQ878190PINAM46I, I54M, L76V, I84VG73A, L89VL10I, I13A, K14KR, L19LI, K20I, L33V, M36I, R41K, K55R, R57RK, D60E, L63P, I66F, H69KCRF02_AG
 48-40814081-30228DQ878310PINAM46L, I54V, I84V L10V, I13A, K14R, K20I, A22V, E35D, M36I, N37S, R41K, Q61H, I66F, H69K, K70R, P79S, L89I, T91TSCRF02_AG
 48-41674167-30423DQ878400PINAM46L, I54V, I84V L10I, I13A, L19P, K20I, A22V, E35D, M36I, N37S, R41K, D60E, I66F, H69K, A71V, L89I, T91S, Q92KCRF02_AG
  4167-40203DQ878401PI, RTV, TPV>41M46L, I54V, I84V L10I, I13A, A22V, E35D, M36I, N37S, R41K, D60E, I66F, H69K, A71V, L89I, T91S, Q92KCRF02_AG
 48-42214221-30429DQ878456PINAM46I, I84VL10F, L33I, G73SI13V, K14R, K20I, E21ED, A22V, M36I, N37D, R41K, L63LP, H69K, K70R, A71V, L89TCRF02_AG
 48-50755075-30807DQ878585PINAM46L, G48T, I54V, V82A, I84VV11VILL10I, T12TS, I13V, K14R, L19P, K20I, E35D, M36I, N37NS, R41K, Q61H, H69K, T74S, L89I, T91SCRF02_AG
 48-71247124-30902DQ878967PINAM46I, I47V, L76V, I84VQ58EL10I, I13A, K14IR, L19P, K20I, M36I, N37D, R41K, K55KR, L63P, H69K, K70R, L89ICRF02_AG
Seyler (2007)545CS_545 IDV170I84VL33I, L89VL10I, I13V, K14R, L19P, K20I, A22V, M36I, N37D, L38I, R41K, L63P, H69K, A71V, T74SCRF02_AG
Rosen-Zvi (2008)105p1-3 LPV, RTV, APV140M46I, V82A, I84VN83DL10V, I13V, K14R, K20R, A22V, M36I, N37D, R41K, Q61H, H69K, K70R, L89ICRF02_AG
 4600p46-1 RTV, SQV, NFV, APV141M46MIL, I54V, V82M, I84V, L90ML33F, Q58EL10V, T12V, I13IV, K14KR, I15V, K20R, E35D, M36I, N37E, R41K, R57K, L63P, H69K, L89ICRF02_AG
Charpentier (2011)CR-34CR-34FJ688240PINAM46I, I54V, I84V L10I, I13A, K14R, K20I, M36I, R41K, K43R, H69K, K70R, A71I, P79S, L89T, Q92K, I93MCRF02_AG
Barber (2012)6078360783JQ361670LPV M46I, I84V L10I, I13V, G16E, Q18QK, L19LP, K20I, E35D, M36I, N37T, P39S, R41K, I62V, H69K, K70R, T74A, L89MCRF02_AG
Kouri (2012)CU294-10CU294-10JQ585376PINAM46L, I54V, I84VQ58E, L89VI13A, L19P, K20I, A22V, L33V, E35D, M36I, N37D, I62IV, L63P, I66F, H69K, A71V, T74A, Q92K, I93IVCRF02_AG
 CU344-10CU344-10JQ585386PINAM46L, I54V, I84VQ58EI13A, K20I, E35N, M36I, Q61QR, L63P, H69K, K70R, A71V, L89TCRF02_AG
 CU1288-10CU1288-10JQ585421PINAM46I, I54L, I84VV11I, L33F, Q58EL10I, I13V, K14R, I15V, G16E, L19P, K20V, E35N, M36I, N37D, K55R, R57RK, Q61H, L63S, H69K, K70R, I72IM, I85V, L89MCRF02_AG
 CU1213-09CU1213-09JQ585280PINAV32I, M46I, I47V, I54L, I84VL33F, F53L, Q58E, L89VL10I, T12E, I13AV, K14R, I15V, G16Q, K20V, E35G, M36I, P39S, R41RK, D60DN, I64V, I66F, H69K, K70E, A71V, I93IVCRF02_AG
Thiam (2013)133-HALD133-HALDJN673604PINAM46I, I47V, I54V, I84VL33I, G73SL10I, V11L, I13V, L19P, K20I, M36I, R41K, Q61H, L63V, H69K, K70R, A71V, I72T, P79A, N83S, L89TCRF02_AG
 1837HALD1837HALDJX187611LPV M46I, I54V, L76V, I84VQ58EL10I, I13V, G16E, K20I, M36I, R41K, L63HR, H69K, K70R, I72V, L89MCRF02_AG
 471-HALD471-HALDJN673637LPV M46I, I47V, I54V, V82A, I84VV11I, F53LL10I, I13V, L19P, K20I, A22V, M36I, N37S, R41K, Q61H, H69K, A71V, L89I, T91SCRF02_AG
 495-HALD495-HALDJN673647LPV M46I, I47V, I54V, I84V, L90ML33I, L89VT4S, L10I, T12M, I13A, K14M, L19P, K20I, A22V, E35D, M36I, N37D, R41RK, R57K, Q61QH, I62IV, L63P, I66F, H69K, A71VCRF02_AG
 6667HALD6667HALDJX187625LPV M46I, L76V, I84VL10F, V11II13V, G16E, L19P, K20I, A22AV, M36I, R41K, L63R, H69K, K70R, L89I, T91ACRF02_AG