<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation L76V
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 22
Isolates 23
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Weber (2005)30239393023939AY677492APV, LPV239M46I, L76V, V82F, I84C L10I, I13V, G16E, K20I, E35D, M36I, N37NK, R41K, L63M, H69K, K70R, T74S, L89MCRF02_AG
Baxter (2006)48-12261226-30417DQ877758PINAM46I, I47V, L76V, I84AV11I, G73S, L89VL10M, I13V, K14R, I15V, Q18I, K20I, M36I, N37D, R41K, H69K, A71V, T74SCRF02_AG
 48-32243224-30624DQ878131PINAM46I, I47IV, L76V, I84VL33LI, Q58EL10I, I13A, K20I, A22V, M36I, R41K, L63P, I66F, H69K, K70R, L89I, T91SCRF02_AG
 48-71247124-30902DQ878967PINAM46I, I47V, L76V, I84VQ58EL10I, I13A, K14IR, L19P, K20I, M36I, N37D, R41K, K55KR, L63P, H69K, K70R, L89ICRF02_AG
Sylla (2008)B202B202_C1EF525647IDV M46I, L76V I13V, K20I, E35N, M36I, R41K, L63P, H69K, L89MCRF02_AG
  B202_C2EF525648IDV M46I, L76V L10V, I13V, K20I, E35N, M36I, R41K, L63P, I66F, H69K, L89MCRF02_AG
Knops (2010)ID0462ID0462-GT2GU271157LPV105M46I, L76V L10V, T12K, I13V, K14R, G16E, L19I, K20I, M36I, R41K, H69K, L89MCRF02_AG
Charpentier (2011)CR-25CR-25FJ688231PINAM46I, L76V, I84IV L10I, I13V, K20I, M36I, R41K, L63P, I66F, H69K, L89MCRF02_AG
 CR-36CR-36FJ688242PINAM46I, L76V L10V, I13V, K14R, G16E, K20I, E35G, M36I, R41K, I62V, I66F, H69K, K70R, L89MCRF02_AG
Rawizza (2013)PJ2562PJ2562KF241497LPV M46I, L76V I13V, K14R, G16E, K20I, E35D, M36I, R41K, Q61QH, I64M, H69K, K70R, L89MCRF02_AG
 LL5309LL5309KF241462LPV M46I, I54V, L76V, V82AL10F, Q58EI13V, I15V, G16E, K20I, E35D, M36I, R41K, L63R, I64M, H69K, K70R, L89M, T91ACRF02_AG
 LN8580LN8580KF241492LPV M46I, I54V, L76V, V82VA, I84IVL89VL10LI, I13V, G16A, K20I, M36I, R41K, H69K, K70R, A71AVCRF02_AG
Thiam (2013)1837HALD1837HALDJX187611LPV M46I, I54V, L76V, I84VQ58EL10I, I13V, G16E, K20I, M36I, R41K, L63HR, H69K, K70R, I72V, L89MCRF02_AG
 674-HALD674-HALDJN673677LPV M46I, L76V I13V, K14R, K20I, M36I, N37E, L63P, I64L, H69K, K70R, L89IMCRF02_AG
 6667HALD6667HALDJX187625LPV M46I, L76V, I84VL10F, V11II13V, G16E, L19P, K20I, A22AV, M36I, R41K, L63R, H69K, K70R, L89I, T91ACRF02_AG
Jenabian (2015)DR25DR25KF735831PINAM46I, L76V I13V, G16E, K20I, E35G, M36I, N37S, R41K, Q61H, L63P, H69K, L89MCRF02_AG
 DR18DR18KF735826PINAM46I, L76V L10LV, I13V, K14R, G17E, K20I, E35ED, M36I, R41K, R57RK, Q61H, L63P, H69K, L89ICRF02_AG
 DR08DR08KF735819PINAM46I, I54V, L76V, I84V L10V, I13A, K20I, M36I, Q61R, I62V, L63S, I66F, H69K, L89I, T91SCRF02_AG
 DR04DR04KF735815PINAM46I, I47V, L76V, I84V L10V, I13A, K20I, E35EG, M36I, I62V, L63P, I66F, H69K, L89I, T91SCRF02_AG
Konou (2015)H534H534KT316160LPV M46I, L76V, I84VL10FI13V, K14R, G16E, K20I, E35D, M36I, N37S, R41K, K55R, R57K, L63R, I64M, H69K, K70R, L89I, T91SCRF02_AG
Abdellaziz (2016)1453014530KT339043PINAM46I, L76V I13V, I15V, K20I, E35EG, M36I, R41K, I64M, H69K, L89MCRF02_AG
 18338MN18338MNKT339001PINAM46I, L76V, I84V L10I, T12S, I13AV, K14R, I15V, K20I, M36I, R41K, I62V, I66F, H69K, L89ICRF02_AG
 1494014940KT339037PINAM46I, I47V, L76V, I84VF53FLL10I, T12S, I13A, K14R, I15V, K20I, M36I, R41K, I62V, I66F, H69K, L89ICRF02_AG