<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation T74S
Rx PI-naive
IncludeMixtures No
References 34
Patients 51
Isolates 52
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Vergne (2000)LVMP1027LVMP1027AJ286954None   L10V, I13V, K14R, G16E, K20I, E35D, M36I, R41K, R57K, H69K, K70R, T74S, L89MCRF02_AG
Eshleman (2001)A059AF357660AF357660None   L10V, I13V, G16E, K20IV, M36I, R41K, H69K, K70R, T74S, L89M, I93LCRF02_AG
Yerly (2001)L6479L6479AY998559None   L10V, I13V, L19P, K20I, M36I, N37E, R41K, H69K, K70R, T74S, V75A, N83NY, L89MCRF02_AG
Toni (2003)TTDdp60TTDdp60AY207703None   I13V, K20I, M36I, P39S, R41K, H69K, T74S, L89MCRF02_AG
Eshleman (2004)ABB52ABB52AY444251None   I13V, K14R, K20I, M36I, R41K, I62V, H69K, K70R, T74S, L89MCRF02_AG
Carr (2005)1569MV1569MVAY847385None   L10V, I13V, K20I, E35Q, M36I, N37D, R41K, H69K, T74S, L89MCRF02_AG
Ndongmo (2006)CM76CBN_CM76DQ394121None   I13V, K20I, E35D, M36I, N37D, H69K, T74S, L89M, I93LCRF02_AG
 CM26CBN_CM26DQ394165None   I13V, K20I, E35N, M36I, R41K, D60E, H69K, T74S, L89M, I93LCRF02_AG
Derache (2007)11561156EF064448None   I13V, K14R, G17D, K20I, E35D, M36I, R41K, I62V, H69K, K70R, T74S, L89MCRF02_AG
Holguin (2007)598078598078EF583226None   I13V, K14R, I15V, K20I, E35N, M36I, R41K, K43R, H69K, T74S, L89MCRF02_AG
Seyler (2007)535CS_535 None   I13V, K20I, M36I, N37D, R41K, H69K, T74S, L89MCRF02_AG
Delgado (2008)GH_054GH_054EU177924None  I47MI13V, K20I, M36I, N37D, R41K, K55R, R57K, Q61QH, H69K, K70R, T74S, L89MCRF02_AG
Derache (2008)BKO-953BKO-953EU330682None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, T74S, L89MCRF02_AG
 SGO-22SGO-22EU330766None   I13V, G17E, K20I, E35D, M36I, R41K, H69K, K70R, T74S, L89MCRF02_AG
 SGO-90SGO-90EU330830None   I13V, G16E, K20I, M36I, N37T, P39S, R41K, H69K, I72M, T74S, L89ICRF02_AG
Palacios (2008)1272912729 None   I13V, K20I, E35D, M36I, N37D, R41K, H69K, T74S, L89MCRF02_AG
Sylla (2008)D604D604_C1DQ991653None   T12I, I13V, K14R, G17E, K20I, E35N, M36I, R41K, I62V, L63S, H69K, T74S, L89MCRF02_AG
  D604_C2DQ991654None   T12I, I13V, K14R, G17E, K20I, E35N, M36I, R41K, I62V, L63S, H69K, T74S, L89MCRF02_AG
Aghokeng (2009)CDC0002CDC0002GU191624None   I13V, I15IL, K20I, M36I, R41K, I62V, G68GE, H69K, T74S, L89MCRF02_AG
Hawkins (2009)Q954ZZQ954FJ931277None   I13V, G16E, K20I, M36I, N37E, P39Q, R41K, I62V, H69K, K70R, T74S, L89MCRF02_AG
 Q960ZZQ960FJ931289None   I13V, K20I, M36I, R41K, R57K, H69K, T74S, L89MCRF02_AG
Koyalta (2009)64TCHAD-64FJ688195None   I13V, K14R, L19I, K20I, M36I, R41K, H69K, T74S, L89MCRF02_AG
Tebit (2009)TR99TR99FJ577283None   L10V, I13V, K14R, K20I, M36I, R41K, C67Y, H69K, T74S, L89MCRF02_AG
 TR161TR161FJ577311None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, R57K, H69K, K70R, T74S, L89MCRF02_AG
Vercauteren (2009)pt13914899365714GQ399633None   I13V, L19Q, K20I, M36I, P39S, R41K, H69K, T74S, L89MCRF02_AG
 pt6339242133246GQ400391None   I13V, K14R, K20I, E35D, M36I, N37D, R41K, H69K, T74S, L89MCRF02_AG
 pt116tYaF4lfcPBGQ400908None   I13V, K14R, K20I, M36I, N37D, R41K, I62V, L63H, H69K, I72M, T74S, L89MCRF02_AG
Yaotse (2009)HT15706TG.HT157FM955744None   I13V, K14R, K20I, E35D, M36I, R41K, D60E, L63P, H69K, T74S, V77I, L89MCRF02_AG
Diop-Ndiaye (2010)925hald925haldFN599758None   I13V, K14R, K20I, M36I, R41K, H69K, K70KR, T74S, L89MCRF02_AG
Germanaud (2010)56215621 None   I13V, K20I, M36I, N37D, R41K, I64L, H69K, T74S, L89MCRF02_AG
Aghokeng (2011)HJ1807HJ1807JN639482None   I13V, K20I, E35D, M36I, P39Q, R41K, H69K, T74S, L89MCRF02_AG
 SK8013-PISK8013-PIHQ864389None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, T74S, L89MCRF02_AG
 SK2028-PISK2028-PIHQ864441None   L10LV, I13V, K14KR, I15IV, K20M, E35D, M36I, R41K, I62IV, L63X, I64IM, H69K, T74S, L89MCRF02_AG
Fokam (2011)CIRCB-10273CIRCB-10273JQ796167None   I13V, K14KR, K20IV, E35D, M36I, R41K, H69K, T74S, L89MCRF02_AG
 CIRCB-10950CIRCB-10950JQ796177None   I13V, K20I, M36I, N37D, R41K, H69K, T74S, L89MCRF02_AG
Hamers (2011)CP076303543CP076303543HQ994022None   I13V, K20I, E35N, M36I, N37D, R41K, K43R, R57RK, H69K, T74S, V77I, L89MCRF02_AG
 CP076303591CP076303591HQ994055None   L10V, I13V, K14R, I15IV, K20I, E35D, M36I, R41K, H69K, T74S, L89MCRF02_AG
Afonso (2012)ANG21ANG21JN937036None   M36I, R41K, H69K, K70R, T74S, L89MCRF02_AG
Caron (2012)Gab013058Gab013058HQ541886None   L10V, T12K, I13V, G17E, K20I, M36I, R41K, I62V, C67Y, H69K, T74S, L89MCRF02_AG
Chamberland (2012)D327TD327THQ267624None   I13V, G17E, K20I, E35D, M36I, N37ND, R41K, H69K, K70R, T74S, L89MCRF02_AG
Ugbena (2012)1-1-0221-1-022JX084007None   K20I, E35D, M36I, N37D, R41K, H69K, T74S, L89MCRF02_AG
 1-1-1841-1-184JX084121None   I15V, K20I, E35Q, M36I, R41K, R57K, Q61E, C67E, H69K, T74S, L89MCRF02_AG
 2-1-1082-1-108JX084223None   K20I, M36I, P39S, R41K, K43KR, H69K, T74S, L89MCRF02_AG
 1-1-1861-1-186JX084123None   K20I, M36I, N37ND, R41K, H69K, T74S, R87KPQT, L89MCRF02_AG
Billong (2013)MR130MR130KF192134None   I13V, K20V, E35D, M36I, R41K, H69K, T74S, L89MCRF02_AG
Nii-Trebi (2013)131084131084AB751414None   I13V, K14R, G17E, K20I, E35D, M36I, R41K, H69K, K70R, T74S, L89MCRF02_AG
 KF12KF12AB751466None   I13A, I15V, K20I, E35D, M36I, N37D, R41K, C67Y, H69K, T74S, L89MCRF02_AG
 KF61KF61AB751476None   I13V, K20I, E35D, M36I, R41K, H69K, T74S, L89MCRF02_AG
Telan (2013)1004165110041651AB747451None   I13V, K20I, M36I, R41K, I62V, H69K, T74S, L89MCRF02_AG
 1106349311063493AB747465None   I13V, K14R, K20I, E35K, M36I, N37D, R41K, K43R, H69K, T74S, L89M, T91ACRF02_AG
Thiam (2013)680-HALD680-HALDJN673692None   I13V, K20I, E35D, M36I, N37D, R41K, H69K, T74S, V77I, L89MCRF02_AG
Stanojevic (2014)RS0545RS0545KF157496None   L10I, I13V, K14R, G16E, K20I, E35D, M36I, R41K, H69K, K70R, T74S, L89MCRF02_AG