<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype CRF02_AG
Gene PR
Mutation T74S
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 16
Isolates 19
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M15M15AY010377PINA L89VL10V, I13V, K14R, L19P, K20I, E35N, M36I, N37D, R41K, H69K, T74SCRF02_AG
 NY_M65M65AY010428PINA L89VL10V, I13V, K14R, L19LP, K20I, E35N, M36I, N37D, R41K, H69K, T74SCRF02_AG
Montes (2004)MB_patKES01_KES716AJ577920NFV136M46I, L90ML89VL10V, I13V, K14R, G16E, K20I, E35D, M36I, R41K, H69K, K70R, T74S, V75ICRF02_AG
 MB_patFEU02_FEU726AJ577889IDV, SQV, RTV190I84V L10V, I13V, K14R, L19P, K20I, E21D, L33V, M36I, N37D, R41K, F53Y, I64L, H69K, K70R, T74S, L89MCRF02_AG
Non-B Workgroup (2005)PL3892365841AY901082SQV, ATV M46I I13V, E35N, M36I, N37D, I64M, H69K, T74S, L89TCRF02_AG
 TK2019TK2019 NFV, SQV, RTV107  I13V, K20I, M36I, N37DE, R41K, H69K, K70R, T74S, L89MCRF02_AG
  TK2019a NFV, SQV, RTV108  I13V, K20I, M36I, N37D, R41K, H69K, K70R, T74S, L89MCRF02_AG
 PL327591552 SQV282I54IV L10IV, I13V, K20I, M36I, R41K, H69K, T74S, V75I, L89MCRF02_AG
  105576 SQV282  L10V, I13V, K20I, M36I, R41K, H69K, T74S, V75I, L89MCRF02_AG
 PL3504797181 IDV, NFV337M46I, L90ML89VL10V, I13V, K14KR, L19LP, K20I, E35G, M36I, N37E, R41K, I62V, H69K, K70R, T74SCRF02_AG
Weber (2005)30239393023939AY677492APV, LPV239M46I, L76V, V82F, I84C L10I, I13V, G16E, K20I, E35D, M36I, N37NK, R41K, L63M, H69K, K70R, T74S, L89MCRF02_AG
Baxter (2006)12-31973197-30821DQ876738PINAI54V, V82AL89VL10V, I13A, K14R, K20I, A22V, M36I, R41K, I62V, H69K, G73D, T74S, T91TSCRF02_AG
  3197-40128DQ876116PI, RTV, TPV>23I54V, V82AL89VL10V, I13A, K14R, K20I, A22V, L33L_L, M36I, R41K, I62V, H69K, G73D, T74S, T91TSCRF02_AG
 48-12261226-30417DQ877758PINAM46I, I47V, L76V, I84AV11I, G73S, L89VL10M, I13V, K14R, I15V, Q18I, K20I, M36I, N37D, R41K, H69K, A71V, T74SCRF02_AG
 48-30903090-30925DQ877999PINAM46I, I47V, I54V, V82C, I84VV11I, L33I, K43T, F53FLL10I, T12M, I13V, K14R, L19P, K20I, A22V, M36I, R41K, K55R, H69K, K70R, I72V, T74S, L89I, T91SCRF02_AG
 48-50755075-30807DQ878585PINAM46L, G48T, I54V, V82A, I84VV11VILL10I, T12TS, I13V, K14R, L19P, K20I, E35D, M36I, N37NS, R41K, Q61H, H69K, T74S, L89I, T91SCRF02_AG
Seyler (2007)027CS_027 NFV165  L10LV, I13V, K20I, M36I, R41K, I64V, H69K, T74S, L89M, I93MCRF02_AG
 545CS_545 IDV170I84VL33I, L89VL10I, I13V, K14R, L19P, K20I, A22V, M36I, N37D, L38I, R41K, L63P, H69K, A71V, T74SCRF02_AG
von Wyl (2007)1105247133EF449805PINAN88S L10I, I13V, K14R, G16E, K20I, E35Q, M36I, R41K, R57K, H69K, T74S, L89MCRF02_AG